Research Topics
Species | Wirote TuntiwechapikulSummaryAffiliation: Chiang Mai University Country: Thailand Publications
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Detail Information
Publications
The influence of pH on the G-quadruplex binding selectivity of perylene derivativesWirote Tuntiwechapikul
Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiangmai 50200, Thailand
Bioorg Med Chem Lett 16:4120-6. 2006..The value of pH and consequent charge formation and self-aggregation of these perylene derivatives influences not only the type of G-quadruplex formation, but also the G-quadruplex binding selectivity...
Ginger extract inhibits human telomerase reverse transcriptase and c-Myc expression in A549 lung cancer cellsWirote Tuntiwechapikul
Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
J Med Food 13:1347-54. 2010..As both telomerase inhibition and Myc inhibition are cancer-specific targets for cancer therapy, ginger extract might prove to be beneficial as a complementary agent in cancer prevention and maintenance therapy...
Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cellsThanachai Taka
Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
Bioorg Med Chem 21:883-90. 2013..The results of this study indicate that perylene derivatives warrant further consideration as effective agents for cancer therapy...
Down-regulation of the human VEGF gene expression by perylene monoimide derivativesThanachai Taka
Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
Bioorg Med Chem Lett 22:518-22. 2012..This study might provide the foundation for the rational design and development of new perylene derivatives as effective anti-angiogenesis agents for cancer therapy...
DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicityWirote Tuntiwechapikul
College of Pharmacy, University of Texas at Austin, PHR 4.220, Austin, Texas 78712-1074, USA
Biochemistry 41:5283-90. 2002..In particular, AZB002 is cytotoxic against a wide range of cancer cell lines...
