Punnee Pitisuttithum

Summary

Affiliation: Center for Infectious Disease and Vaccine Research
Country: Thailand

Publications

  1. doi request reprint Factors associated with incarceration and incident human immunodeficiency virus (HIV) infection among injection drug users participating in an HIV vaccine trial in Bangkok, Thailand, 1999-2003
    Pravan Suntharasamai
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Addiction 104:235-42. 2009
  2. ncbi request reprint Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    Punnee Pitisuttithum
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    J Infect Dis 194:1661-71. 2006
  3. ncbi request reprint Efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-vir) in advanced HIV infection
    Aneley Getahun
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 89:1472-8. 2006
  4. ncbi request reprint Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand
    Nyan Lin Kyaw
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 44:232-43. 2013
  5. ncbi request reprint Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:494-501. 2009
  6. ncbi request reprint 6-month evaluation of JinHuang Chinese herbal medicine study in asymptomatic HIV infected Thais
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:379-84. 2003
  7. ncbi request reprint Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1
    Punnee Pitisuttithum
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Acquir Immune Defic Syndr 37:1160-5. 2004
  8. ncbi request reprint Effectiveness of fixed-dose combination stavudine, lamivudine and nevirapine (GPO-VIR) for treatment of naïve HIV patients in Thailand: a 3-year follow-up
    Varunee Desakorn
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 42:1414-22. 2011
  9. ncbi request reprint Social harms in injecting drug users participating in the first phase III HIV vaccine trial in Thailand
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 90:2442-8. 2007
  10. ncbi request reprint Long term outcomes of nevirapine containing antiretroviral therapy at a center in Thailand
    Wai Lin Htun
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:860-70. 2012

Collaborators

Detail Information

Publications44

  1. doi request reprint Factors associated with incarceration and incident human immunodeficiency virus (HIV) infection among injection drug users participating in an HIV vaccine trial in Bangkok, Thailand, 1999-2003
    Pravan Suntharasamai
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Addiction 104:235-42. 2009
    ..To determine if incarceration was associated with human immunodeficiency virus (HIV) infection and identify risk factors for incarceration among injection drug users (IDUs) participating in an HIV vaccine trial in Bangkok...
  2. ncbi request reprint Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    Punnee Pitisuttithum
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    J Infect Dis 194:1661-71. 2006
    ....
  3. ncbi request reprint Efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-vir) in advanced HIV infection
    Aneley Getahun
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 89:1472-8. 2006
    ..To assess the efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine; GPO-vir in advanced HIV infection...
  4. ncbi request reprint Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand
    Nyan Lin Kyaw
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 44:232-43. 2013
    ..401) and virologic rebound (p=0.562) were not significantly associated with the baseline CD4 count. This study shows the outcome after onset of ART did not vary by baseline CD4 cell count...
  5. ncbi request reprint Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:494-501. 2009
    ..019). CKBM-A01 appeared to be safe but gave no significant improvement in QoL in asymptomatic HIV patients, and gave no significant improvement in the treatment of HIV based on CD4 cell counts and viral loads...
  6. ncbi request reprint 6-month evaluation of JinHuang Chinese herbal medicine study in asymptomatic HIV infected Thais
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:379-84. 2003
    ..Most of the patients felt that the quality of life was better in terms of better appetite, good sleep and healthy during study participation, however, these were subjective...
  7. ncbi request reprint Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1
    Punnee Pitisuttithum
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Acquir Immune Defic Syndr 37:1160-5. 2004
    ..Using the B/E combination did not interfere with the response to either clade. Antibodies to AIDSVAX B/E were able to bind to oligomeric gp120 on the surface of cells infected with primary isolates of HIV-1...
  8. ncbi request reprint Effectiveness of fixed-dose combination stavudine, lamivudine and nevirapine (GPO-VIR) for treatment of naïve HIV patients in Thailand: a 3-year follow-up
    Varunee Desakorn
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 42:1414-22. 2011
    ..3%). Thirty-six patients (27%) switched from GPO-VIR to other anti-retroviral drugs regimens due to lipodystrophy. This study showed GPO-VIR had clinical and immunological benefits, but one-third of patients had adverse effects...
  9. ncbi request reprint Social harms in injecting drug users participating in the first phase III HIV vaccine trial in Thailand
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 90:2442-8. 2007
    ..To study related social harms due to identification with a group of participants in an HIV-1 vaccine trial who are potentially high risk for HIV/AIDS...
  10. ncbi request reprint Long term outcomes of nevirapine containing antiretroviral therapy at a center in Thailand
    Wai Lin Htun
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:860-70. 2012
    ..Elevated liver enzymes occurred in 5 patients after 5 years. NVP-containing ART yielded high virological-success rates. Long-term immunological response, safety and durability were also high...
  11. ncbi request reprint Immune reconstitution inflammatory syndrome in adult human immunodeficiency virus-infected patients in Thailand
    Maie Aramaki
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok Thailand
    Southeast Asian J Trop Med Public Health 41:138-45. 2010
    ..001). The incidence of IRIS in advanced adult HIV-infected patients in Thailand was lower than that reported from Europe and the United States, which may be attributable to deferment of HAART after diagnosing opportunistic infections...
  12. pmc Safety and reactogenicity of canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E vaccination in an efficacy trial in Thailand
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 6:e27837. 2011
    ..2% for prevention of HIV acquisition in HIV-uninfected adults participating in a community-based efficacy trial in Thailand...
  13. pmc The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope
    Mark S de Souza
    U S Military HIV Research Program U S Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand
    J Immunol 188:5166-76. 2012
    ..Although the RV144 T cell responses were modest in frequency compared with humoral immune responses, the CD4(+) T cell response was directed to HIV-1 Env and more particularly the V2 region...
  14. pmc Clinical Factors for Severity of Plasmodium falciparum Malaria in Hospitalized Adults in Thailand
    Patrick Sagaki
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Amudat Hospital, Amudat, Uganda
    PLoS ONE 8:e71503. 2013
    ..Early identification and the timely initiation of appropriate treatments may well improve the outcomes and reduce the mortality of these patients. ..
  15. ncbi request reprint Comparison of clinical outcomes between HIV-infected patients with and without HCV co-infection in a resource-limited setting
    Nan Nitra Than
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:646-51. 2012
    ..Further studies are needed to assess the long-term impact of HCV co-infection on clinical outcomes in HIV-infected patients without HCV treatment...
  16. ncbi request reprint Safety and immunogenicity of combinations of recombinant subtype E and B human immunodeficiency virus type 1 envelope glycoprotein 120 vaccines in healthy Thai adults
    Punnee Pitisuttithum
    Vaccine Trial Centre, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Siriraj Hospital, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Infect Dis 188:219-27. 2003
    ..There was no evidence of antigenic interference in HIV-specific humoral or cellular responses. The gp120 Thai E and SF2 vaccines were safe and immunogenic in combination and could be advanced into phase 3 testing...
  17. doi request reprint Safety and immune responses following administration of H1N1 live attenuated influenza vaccine in Thais
    Benjaluck Phonrat
    Department of Clinical Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Ratchathewi, Bangkok 10400, Thailand
    Vaccine 31:1503-9. 2013
    ..The Thai Government Pharmaceutical Organization (GPO) with technical support from Russia through WHO had prepared a pandemic live attenuated vaccine (PLAIV) using ca-ts attenuated candidate strain A/17/CA/2009/38 (H1N1) for Thais...
  18. ncbi request reprint Knowledge, attitudes, and acceptability of a human papilloma virus vaccine among students, parents and teachers in Thailand
    Archin Songthap
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:340-53. 2012
    ..Greater effort may be needed to educate people regarding the cost and benefits of HPV vaccination before it would be more acceptable to parents, teachers and students in Thailand...
  19. doi request reprint HIV vaccine research in Thailand: lessons learned
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, 40 6 Ratchavithi Road, Ratchathewi, Bangkok 10400, Thailand
    Expert Rev Vaccines 7:311-7. 2008
    ..However, many lessons learned can be utilized or modified for other vaccine trials, particularly vaccines against other infectious diseases prevalent in developing countries...
  20. ncbi request reprint Psychosocial burden of women with abnormal Pap smears
    Benjaluck Phonrat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:593-601. 2009
    ....
  21. pmc The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120
    Nicos Karasavvas
    Department of Retrovirology, U S Army Medical Component, Armed Forces Research Institute of Medical Sciences, USAMC AFRIMS, Bangkok 10400, Thailand
    AIDS Res Hum Retroviruses 28:1444-57. 2012
    ..Early HIV-1 transmission events involve V2 loop interactions, raising the possibility that anti-V2 antibodies in RV144 may have contributed to viral inhibition...
  22. ncbi request reprint HIV-1 prophylactic vaccine trials in Thailand
    Punnee Pitisuttithum
    Clinical Infectious Diseases Research Unit, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Curr HIV Res 3:17-30. 2005
    ..With committed parties in medical science, government, industry and the community, we hope that we can achieve success in developing a safe and effective HIV vaccine in the near future...
  23. doi request reprint HIV-vaccine research and development in Thailand: evolution and challenges
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University 420 6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand
    Vaccine 28:B45-9. 2010
    ..However, there were different issues in recruitment process, follow up, social impact events and community involvement since the target participants were different...
  24. ncbi request reprint Seroprevalence of latent cytomegalovirus infection among elderly Thais
    Viravarn Luvira
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:1419-25. 2012
    ..Further studies with large number of patients are needed to explore these findings...
  25. ncbi request reprint Knowledge, attitudes, and acceptability of a human papillomavirus vaccine among healthcare providers
    Archin Songthap
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:1048-56. 2009
    ..Almost all the nurses and doctors suggested that adolescent aged < or = 18-years-old should be the target group for HPV vaccination. Furthermore, 73% of nurses and 76% of doctors would recommend clients to receive HPV vaccine...
  26. ncbi request reprint Evaluation of attitude, risk behavior and expectations among Thai participants in Phase I/II HIV/AIDS vaccine trials
    Wirach Maek-A-Nantawat
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 86:299-307. 2003
    ..0001). All of the volunteers expressed the beneficial expectations as knowledge gain, social contribution, feelings of having gained merit and self-benefits from health check-ups...
  27. pmc Pregnancy Outcomes Among HIV-Infected Women Undergoing Antiretroviral Therapy
    Darin Areechokchai
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Open AIDS J 3:8-13. 2009
    ..004). CONCLUSION: Adverse ARV events were more numerous among the pregnant women who needed ART than PMTCT. ANC is beneficial and strongly recommended for all pregnant HIV-infected women for better pregnancy outcomes...
  28. ncbi request reprint Clinical features, aetiology and short-term outcome of interstitial pneumonitis in HIV/AIDS patients at Bamrasnaradura Hospital, Nonthaburi, Thailand
    Ariane Knauer
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Wien Klin Wochenschr 117:49-55. 2005
    ..6% had clinically improved. The cumulative survival after 28 days was highest among PCP patients, followed by bacterial pneumonia, TB and fungal pneumonia, but these differences were statistically not significant (p = 0.453)...
  29. ncbi request reprint The efficacy and adverse effects of GPO-VIR (stavudine+lamivudine+nevirapine) in treatment-naïve adult HIV patients
    Ei Ei Tin
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:362-9. 2005
    ..043). GPO-VIR is an inexpensive and effective antiretroviral drug regimen for initiating treatment of naïve patients, but careful assessment for lipodystrophy is necessary, especially after one year of treatment...
  30. pmc Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2
    Arjen M Dondorp
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Med 2:e204. 2005
    ..P. falciparum releases a specific histidine-rich protein (PfHRP2) into plasma. Quantitative measurement of plasma PfHRP2 concentrations may reflect the total parasite biomass in falciparum malaria...
  31. ncbi request reprint Clinical and mycological responses to fluconazole and fluconazole MIC in oropharyngeal candidiasis in HIV-infected patients
    Valai Bussaratid
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:757-64. 2002
    ..Although some patients are asymptomatic, progression of the disease may occur leading to esophageal candidiasis. Fluconazole resistant candidiasis has been reported in several international studies...
  32. ncbi request reprint Mycobacterium tuberculosis infection among HIV/AIDS patients in Thailand: clinical manifestations and outcomes
    Nimfa M Putong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:346-51. 2002
    ..Among those who survived, only 11.4% had been successfully treated; the rest had not improved due to relapse (2.9%), therapeutic failure (8.8%), treatment in progress (5.9%), and failure to complete treatment (10.7%)...
  33. ncbi request reprint A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis
    Paul N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 35:769-72. 2002
    ....
  34. ncbi request reprint Recruiting volunteers for a multisite phase I/II HIV preventive vaccine trial in Thailand
    Darawan Thapinta
    Faculty of Nursing and Research Institute of Health Sciences, Chiang Mai University, Chiang Mai, Thailand
    J Acquir Immune Defic Syndr 30:503-13. 2002
    ..The frequent presence of mixed (altruistic and nonaltruistic) motives at initial contact suggests that motivation for trials is more complex than has been previously acknowledged...
  35. ncbi request reprint Specific antibody responses to vaccination with bivalent CM235/SF2 gp120: detection of homologous and heterologous neutralizing antibody to subtype E (CRF01.AE) HIV type 1
    Jerome H Kim
    U S Military HIV Research Program, Rockville, Maryland 20850, USA
    AIDS Res Hum Retroviruses 19:807-16. 2003
    ..Whether the NAb detected by the CM235M4-C4.6/A3R5 system is qualitatively different from those in more traditional NP03/H9 assays will require further study...
  36. ncbi request reprint Lack of increased HIV risk behavior among injection drug users participating in the AIDSVAX B/E HIV vaccine trial in Bangkok, Thailand
    Frits van Griensvan
    Thailand Ministry of Public Health US Centers for Disease Control and Prevention Collaboration, Nonthaburi
    AIDS 18:295-301. 2004
    ..To determine whether HIV vaccine trial participation leads to increased risk behavior through beliefs about vaccine protection against infection...
  37. ncbi request reprint Recruitment, screening and characteristics of injection drug users participating in the AIDSVAX B/E HIV vaccine trial, Bangkok, Thailand
    Suphak Vanichseni
    Thailand Ministry of Public Health US Centers for Disease Control and Prevention Collaboration, Nonthaburi
    AIDS 18:311-6. 2004
    ....
  38. ncbi request reprint Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults
    Sorachai Nitayaphan
    Royal Thai Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 190:702-6. 2004
    ..This vaccine combination was well tolerated and was immunogenic, meeting milestones for advancement to phase 3 evaluation...
  39. ncbi request reprint Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand
    Chitraporn Karnasuta
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Vaccine 23:2522-9. 2005
    ..The results demonstrate that this HIV vaccine is a potent inducer of ADCC activity and may be an additional protection of this prime-boost vaccine in preventing HIV disease...
  40. ncbi request reprint Behavioral and social issues among volunteers in a preventive HIV vaccine trial in Thailand
    Richard A Jenkins
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Acquir Immune Defic Syndr 40:592-9. 2005
    ..Findings add to the evidence that preventive HIV vaccine trials are feasible in Thailand...
  41. ncbi request reprint Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents
    Paul M Coplan
    Merck Research Laboratories, West Point, Pennsylvania, USA
    J Infect Dis 191:1427-34. 2005
    ..Therefore, we quantified the cross-clade reactivity, among unvaccinated individuals, of anti-HIV-1 T cell responses to the infecting HIV-1 clade relative to other major circulating clades...
  42. ncbi request reprint Clinical features, etiology and short term outcomes of interstitial pneumonitis in HIV/AIDS patients
    Somsit Tansuphasawadikul
    Bamrasnaradura Hospital, Ministry of Public Health, Nonthaburi, Thailand
    Southeast Asian J Trop Med Public Health 36:1469-78. 2005
    ..The cumulative survival after 28 days was highest among PCP patients, followed by bacterial pneumonia, tuberculosis and fungal pneumonia, but this difference was not statistically significant (p = 0.0453)...
  43. ncbi request reprint Predisposing factors for nevirapine toxicity among AIDS patients with low baseline CD4 count
    Somsit Tansuphaswadikul
    Bamrasnaradura Institute, Ministry of Public Health, Nonthaburi, Thailand
    Asian Pac J Allergy Immunol 25:147-54. 2007
    ....
  44. ncbi request reprint Comparison of one week with two week regimens of amphotericin B both followed by fluconazole in the treatment of cryptococcal meningitis among AIDS patients
    Somsit Tansuphaswadikul
    Bamrasnaradura Infectious Disease Institute, Department of Disease Control, Nonthaburi
    J Med Assoc Thai 89:1677-85. 2006
    ..Amphotericin B treatment in cryptococcosis requires daily hospital visits or admission. Its toxicities and hospital costs have been concerned. Short course amphotericin B regimen warrants to be evaluated...