Robert V Gibbons

Summary

Affiliation: Armed Forces Research Institute of Medical Sciences
Country: Thailand

Publications

  1. doi request reprint Dengue conundrums
    Robert V Gibbons
    Department of Virology, Armed Forces Research Institute of Medical Research, Bangkok, Thailand
    Int J Antimicrob Agents 36:S36-9. 2010
  2. pmc Dengue and US military operations from the Spanish-American War through today
    Robert V Gibbons
    Armed Forces Research Institute of Medical Science, Bangkok, Thailand
    Emerg Infect Dis 18:623-30. 2012
  3. ncbi request reprint Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequences
    Robert V Gibbons
    Department of Virology, United States Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 77:910-3. 2007
  4. pmc Fine scale spatiotemporal clustering of dengue virus transmission in children and Aedes aegypti in rural Thai villages
    In Kyu Yoon
    Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS Negl Trop Dis 6:e1730. 2012
  5. pmc Underrecognized mildly symptomatic viremic dengue virus infections in rural Thai schools and villages
    In Kyu Yoon
    Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 206:389-98. 2012
  6. doi request reprint Incidence of leptospirosis in a select population in Nepal
    Khin Saw Aye Myint
    Armed Forces Research Institute of Medical Sciences AFRIMS, Bangkok, Thailand
    Trans R Soc Trop Med Hyg 104:551-5. 2010
  7. pmc Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006
    Jessica R Fried
    Mahidol Oxford Tropical Medicine Research Unit MORU, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 4:e617. 2010
  8. pmc Factors influencing dengue virus isolation by C6/36 cell culture and mosquito inoculation of nested PCR-positive clinical samples
    Richard G Jarman
    Department of Virology, United States Army Medical Component, Armed Forces Research, Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 84:218-23. 2011
  9. pmc Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: How alterations in assay conditions impact performance
    Stephen J Thomas
    Department of Virology, United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 81:825-33. 2009
  10. pmc Evaluation of diagnostic assays for hepatitis E virus in outbreak settings
    Khin Saw Aye Myint
    Department of Virology, USAMC AFRIMS, 315 6 Rajvithi Road, Bangkok 1040, Thailand
    J Clin Microbiol 44:1581-3. 2006

Detail Information

Publications46

  1. doi request reprint Dengue conundrums
    Robert V Gibbons
    Department of Virology, Armed Forces Research Institute of Medical Research, Bangkok, Thailand
    Int J Antimicrob Agents 36:S36-9. 2010
    ..The existence of multiple serotypes can result in more severe disease upon a second infection and complicates vaccine development. Nevertheless, a safe and effective vaccine is the greatest prospect for stemming the tide of dengue...
  2. pmc Dengue and US military operations from the Spanish-American War through today
    Robert V Gibbons
    Armed Forces Research Institute of Medical Science, Bangkok, Thailand
    Emerg Infect Dis 18:623-30. 2012
    ..The increase in dengue throughout the world suggests that it will remain a problem for military personnel until an effective vaccine is licensed...
  3. ncbi request reprint Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequences
    Robert V Gibbons
    Department of Virology, United States Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 77:910-3. 2007
    ..We document new dengue serotype infection sequences leading to DHF of 1-4, 2-3, 3-1, and 3-4...
  4. pmc Fine scale spatiotemporal clustering of dengue virus transmission in children and Aedes aegypti in rural Thai villages
    In Kyu Yoon
    Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS Negl Trop Dis 6:e1730. 2012
    ..To define the dimensions of local transmission and quantify the factors that support it, we examined relationships between infected humans and Aedes aegypti in Thai villages...
  5. pmc Underrecognized mildly symptomatic viremic dengue virus infections in rural Thai schools and villages
    In Kyu Yoon
    Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 206:389-98. 2012
    ..Geographic cluster studies can elucidate these features in greater detail than cohort studies alone...
  6. doi request reprint Incidence of leptospirosis in a select population in Nepal
    Khin Saw Aye Myint
    Armed Forces Research Institute of Medical Sciences AFRIMS, Bangkok, Thailand
    Trans R Soc Trop Med Hyg 104:551-5. 2010
    ..Leptospirosis should be considered in the differential diagnosis of febrile illnesses and icteric syndromes in Nepal. Additional studies are needed to establish the broader distribution and the spectrum of disease in Nepal...
  7. pmc Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006
    Jessica R Fried
    Mahidol Oxford Tropical Medicine Research Unit MORU, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 4:e617. 2010
    ..It is unclear whether dengue serotypes differ in their propensity to cause severe disease. We analyzed differences in serotype-specific disease severity in children presenting for medical attention in Bangkok, Thailand...
  8. pmc Factors influencing dengue virus isolation by C6/36 cell culture and mosquito inoculation of nested PCR-positive clinical samples
    Richard G Jarman
    Department of Virology, United States Army Medical Component, Armed Forces Research, Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 84:218-23. 2011
    ..Dengue serotypes also played a role in the success of viral isolation...
  9. pmc Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: How alterations in assay conditions impact performance
    Stephen J Thomas
    Department of Virology, United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 81:825-33. 2009
    ..Investigators varied cell type, control virus passage, and the use of complement across multiple assay runs of the same sample panel. Our findings indicate wide variation in PRNT titer results in response to varied testing conditions...
  10. pmc Evaluation of diagnostic assays for hepatitis E virus in outbreak settings
    Khin Saw Aye Myint
    Department of Virology, USAMC AFRIMS, 315 6 Rajvithi Road, Bangkok 1040, Thailand
    J Clin Microbiol 44:1581-3. 2006
    ..The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific...
  11. doi request reprint Clinical performance of a rapid influenza test and comparison of nasal versus throat swabs to detect 2009 pandemic influenza A (H1N1) infection in Thai children
    Piyarat Suntarattiwong
    Queen Sirikit National Institute of Child Health Department of Medical Service, Ministry of Public Health, Bangkok, Thailand
    Pediatr Infect Dis J 29:366-7. 2010
    ..2% (95% CI: 98-100). In the 0 to 2 years age group, sensitivity was 76.7% (95% CI: 61.5-91.8). Throat and nasal swabs are equally useful diagnostic specimens for reverse transcription-polymerase chain reaction diagnosis...
  12. pmc Safety and immunogenicity of a tetravalent live-attenuated dengue vaccine in flavivirus-naive infants
    Veerachai Watanaveeradej
    Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand
    Am J Trop Med Hyg 85:341-51. 2011
    ..6% developed tetravalent neutralizing antibodies ≥ 1:10 to DENV (control group = 0%). This vaccine candidate, therefore, warrants continued development in this age group (NCT00322049; clinicaltrials.gov)...
  13. doi request reprint A model international partnership for community-based research on vaccine-preventable diseases: the Kamphaeng Phet-AFRIMS Virology Research Unit (KAVRU)
    Robert V Gibbons
    Armed Forces Research Institute of Medical Science, Department of Virology, Bangkok, Thailand Electronic address
    Vaccine 31:4487-500. 2013
    ..To provide a base for continuing studies, The Kamphaeng Phet-AFRIMS Virology Research Unit (KAVRU) was established. This paper reviews the origins of the collaboration and the scientific observations made between 1982 and 2012. ..
  14. pmc Comparison of seven commercial antigen and antibody enzyme-linked immunosorbent assays for detection of acute dengue infection
    Stuart D Blacksell
    Mahidol University Oxford Tropical Medicine Research Unit MORU, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Vaccine Immunol 19:804-10. 2012
    ..This study provides strong evidence of the value of combining dengue virus antigen- and antibody-based test results in the ELISA format for the diagnosis of acute dengue infection...
  15. ncbi request reprint Clinical intervention and molecular characteristics of a dengue hemorrhagic fever outbreak in Timor Leste, 2005
    Siripen Kalayanarooj
    Queen Sirikit National Institute of Child Health, Bangkok, Thailand
    Am J Trop Med Hyg 77:534-7. 2007
    ..Although cause and effect cannot be definitely attributed, the case fatality rate decreased to 3.6% after the intervention with education about dengue management strategies...
  16. ncbi request reprint Hepatitis E virus infection in Thai troops deployed with U.N. peacekeeping forces
    Khin Saw Aye Myint
    Department of Virology, U S Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand
    Mil Med 172:1217-9. 2007
    ..N. multinational forces. With an average deployment of 6.4 months, the annualized seroconversion rates after deployments to East Timor, Afghanistan, Burundi, and Iraq were 1.9%, 4.6%, 4.6%, and 3.9%, respectively...
  17. ncbi request reprint Blood group AB is associated with increased risk for severe dengue disease in secondary infections
    Siripen Kalayanarooj
    Queen Sirikit National Institute of Child Health, US Army Medical Corps Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 195:1014-7. 2007
    ..0001; odds ratio, 0.119 [95% confidence interval, 0.04-0.37]). To our knowledge, this is the first report demonstrating an association between ABO blood group and the severity of dengue disease...
  18. doi request reprint Hepatitis antibody profile of Royal Thai Army nursing students
    Chaiyaphruk Pilakasiri
    Analytical Division, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Trop Med Int Health 14:609-11. 2009
    ..8%, 0.5% and 11.5%, respectively. The highest seroprevalence to hepatitis A was observed in cadets from the southern region of Thailand. Seroprevalence rates to hepatitis A and B were less than in other reported studies in Thailand...
  19. pmc Dengue virus detection using whole blood for reverse transcriptase PCR and virus isolation
    Chonticha Klungthong
    Armed Forces Research Institute of Medical Sciences, Department of Virology, Bangkok, Thailand
    J Clin Microbiol 45:2480-5. 2007
    ..Using a selection of these samples, we also found that our ability to detect virus by direct C6/36 cell culture and mosquito inoculation was enhanced by using whole blood but not to the same extent as that seen by the use of RT-PCR...
  20. pmc Characteristics of mild dengue virus infection in thai children
    In Kyu Yoon
    Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand University of Massachusetts Medical School, Worcester, Massachusetts Department of Medicine, University of Toronto, Toronto, Ontario, Canada Department of Entomology, University of California, Davis, Davis, California Department of Geography, University at Buffalo, Buffalo, New York Bureau of Epidemiology, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand Department of Infectious Diseases, State University of New York, Syracuse, Syracuse, New York Institute for Immunology and Informatics, University of Rhode Island, Providence, Rhode Island Fogarty International Center, National Institutes of Health, Bethesda, Maryland
    Am J Trop Med Hyg 89:1081-7. 2013
    ..Mild infections identified by cluster investigations account for a major proportion of all DENV infections. These findings are relevant for disease burden assessments, transmission modeling, and determination of vaccine impact...
  21. doi request reprint The impact of primer and probe-template mismatches on the sensitivity of pandemic influenza A/H1N1/2009 virus detection by real-time RT-PCR
    Chonticha Klungthong
    Department of Virology, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    J Clin Virol 48:91-5. 2010
    ..The results from the WHO swH1 primer and probe set exhibited diverse sensitivities for the 2009 influenza A/H1N1 strains in Southeast Asia (SEA)...
  22. ncbi request reprint Hospital-based surveillance of Japanese encephalitis at a tertiary hospital in Manila
    Ma Theresa P Alera
    Department of Virology, US Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 44:791-8. 2013
    ..Further studies on the nation-wide prevalence and distribution of JE in the Philippines are needed to guide health authorities in disease control and prevention strategies...
  23. pmc Human metapneumovirus reinfection among children in Thailand determined by ELISA using purified soluble fusion protein
    Julie A Pavlin
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, USA
    J Infect Dis 198:836-42. 2008
    ..Human metapneumovirus (hMPV) is a newly discovered paramyxovirus that causes acute respiratory illness. Despite apparent near-universal exposure during early childhood, immunity is transient...
  24. pmc Microevolution of Dengue viruses circulating among primary school children in Kamphaeng Phet, Thailand
    Richard G Jarman
    Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok, Thailand 10400
    J Virol 82:5494-500. 2008
    ..These results suggest that frequent viral migration into Kamphaeng Phet, coupled with population (school) subdivision, shapes the genetic diversity of DENV on a local scale, more so than in situ evolution within school catchment areas...
  25. doi request reprint Serological response to Bartonella species in febrile patients from Nepal
    Khin Saw Aye Myint
    U S Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Trans R Soc Trop Med Hyg 105:740-2. 2011
    ..Our preliminary study, a retrospective serological survey of archived specimens, suggests that Bartonella antibodies are prevalent among febrile patients in the Kathmandu Valley of Nepal...
  26. ncbi request reprint Safety and immunogenicity of a tetravalent live-attenuated dengue vaccine in flavivirus naive children
    Sriluck Simasathien
    Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand
    Am J Trop Med Hyg 78:426-33. 2008
    ..gov NCT00384670)...
  27. ncbi request reprint Hepatitis E: a neglected threat
    Khin Saw Aye Myint
    Department of Virology, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 102:211-2. 2008
    ..In this review, the progress made in hepatitis E research and the recently concluded vaccine trial of the recombinant protein vaccine are briefly discussed...
  28. pmc A prospective assessment of the accuracy of commercial IgM ELISAs in diagnosis of Japanese encephalitis virus infections in patients with suspected central nervous system infections in Laos
    Catrin E Moore
    Wellcome Trust Mahosot Hospital Oxford Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Lao PDR
    Am J Trop Med Hyg 87:171-8. 2012
    ..2% (95% CI = 87-100) with Panbio Ravi criteria. Specificities were 89-100%. For admission sera from AES patients, sensitivities and specificities of the Panbio ELISA were 85.7% (95% CI = 42-100%) and 92.9% (95% CI = 83-98%), respectively...
  29. ncbi request reprint Leptospirosis in Kamphaeng Phet, Thailand
    Khin S A Myint
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 76:135-8. 2007
    ..Leptospirosis was found to be a frequently confirmed cause of morbidity in Kamphaeng Phet Province in those suspected of having the illness...
  30. doi request reprint Evaluation of QuickVue influenza A+B rapid test for detection of pandemic influenza A/H1N1 2009
    John Mark S Velasco
    Department of Virology, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok, 10400 Thailand
    J Clin Virol 48:120-2. 2010
    ..In the Philippines, pandemic influenza A/H1N1 2009 was first detected in May 2009 and by July 2009, 3207 cases and 6 deaths were reported...
  31. ncbi request reprint Unravelling the neuropathogenesis of Japanese encephalitis
    Khin Saw Aye Myint
    Department of Virology, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 101:955-6. 2007
    ..A better understanding of these mechanisms may lead to therapeutic strategies to reduce brain injury and neurological sequelae...
  32. doi request reprint Influenza surveillance from November 2008 to 2011; including pandemic influenza A(H1N1)pdm09 in Bhutan
    Sonam Wangchuk
    Public Health Laboratory, Department of Public Health, Ministry of Health, Thimphu, Bhutan
    Influenza Other Respir Viruses 7:426-30. 2013
    ..Describe the influenza A(H1N1) pandemic in Bhutan...
  33. ncbi request reprint Hepatitis B among pregnant women attending health care facilities in rural Bangladesh
    Md Shamsuzzaman
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 42:1410-3. 2011
    ..Hepatitis B has a low prevalence among pregnant women in rural Bangladesh. Existing hepatitis B vaccination schedule in the Expanded Program on Immunization (EPI) to vaccinate the children in rural Bangladesh is appropriate...
  34. ncbi request reprint Hepatitis E antibody kinetics in Nepalese patients
    Khin Saw Aye Myint
    Department of Virology, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 100:938-41. 2006
    ..Study data contribute to an understanding of the pathophysiology of human hepatitis E and set an antibody response pattern to be targeted as a part of HEV vaccine development...
  35. pmc Evidence for subclinical avian influenza virus infections among rural Thai villagers
    Benjawan P Khuntirat
    Department of Virology, US Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Clin Infect Dis 53:e107-16. 2011
    ..Kamphaeng Phet Province, in north-central Thailand had over 50 HPAI poultry outbreaks in 2004 alone, and 1 confirmed and 2 likely other human HPAI infections between 2004 and 2006...
  36. ncbi request reprint Evaluation of three immunoglobulin M antibody capture enzyme-linked immunosorbent assays for diagnosis of Japanese encephalitis
    Julie A Jacobson
    Japanese Encephalitis Project, PATH, Seattle, Washington 98107, USA
    Am J Trop Med Hyg 77:164-8. 2007
    ..This information is helpful in considering options for strengthening the laboratory component of JE surveillance...
  37. pmc Identification of all dengue serotypes in Nepal
    Sarala Malla
    Emerg Infect Dis 14:1669-70. 2008
  38. pmc Prospective study to determine accuracy of rapid serological assays for diagnosis of acute dengue virus infection in Laos
    Stuart D Blacksell
    Wellcome Trust Mahosot Hospital Oxford Tropical Medicine Research Collaboration, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR
    Clin Vaccine Immunol 14:1458-64. 2007
    ..The findings of this study suggest that currently available RDTs based on the detection of IgM antibodies for the diagnosis of acute dengue virus infections are unlikely to be useful for patient management...
  39. ncbi request reprint Evaluation of the Panbio dengue virus nonstructural 1 antigen detection and immunoglobulin M antibody enzyme-linked immunosorbent assays for the diagnosis of acute dengue infections in Laos
    Stuart D Blacksell
    Wellcome Trust Mahosot Hospital Oxford Tropical Medicine Research Collaboration, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR
    Diagn Microbiol Infect Dis 60:43-9. 2008
    ....
  40. pmc Global distribution of novel rhinovirus genotype
    Thomas Briese
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 14:944-7. 2008
    ..Molecular dating indicates that these viruses have been circulating for at least 250 years...
  41. doi request reprint A new quantitative RT-PCR method for sensitive detection of dengue virus in serum samples
    Nadine Sadon
    GlaxoSmithKline Biologicals, Research and Development, Viral Vaccines, Rixensart, Belgium
    J Virol Methods 153:1-6. 2008
    ..It is shown that the Q-PCR is a rapid, sensitive and reproducible tool for the detection and quantitation of the four dengue serotypes in clinical samples, and therefore of great interest for diagnostic use or for large cohort studies...
  42. ncbi request reprint Natural history of plasma leakage in dengue hemorrhagic fever: a serial ultrasonographic study
    Anon Srikiatkhachorn
    Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Pediatr Infect Dis J 26:283-90; discussion 291-2. 2007
    ..We employed serial ultrasound examination to delineate the locations and the timing of plasma leakage and to evaluate the usefulness of ultrasound in detecting plasma leakage in DHF...
  43. ncbi request reprint Laboratory-based Japanese encephalitis surveillance in Nepal and the implications for a national immunization strategy
    Thomas F Wierzba
    Naval Medical Research Unit No 2, Phnom Penh, Cambodia
    Am J Trop Med Hyg 78:1002-6. 2008
    ....
  44. ncbi request reprint Clinical practice. Prophylaxis against rabies
    Charles E Rupprecht
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 351:2626-35. 2004
  45. pmc Dengue: an escalating problem
    Robert V Gibbons
    Department of Virus Diseases, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    BMJ 324:1563-6. 2002
  46. ncbi request reprint An evaluation of hospitalizations for Kawasaki syndrome in Georgia
    Robert V Gibbons
    Division for Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Mail Stop A 39, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    Arch Pediatr Adolesc Med 156:492-6. 2002
    ..To evaluate and describe the epidemiologic characteristics of Kawasaki syndrome (KS) hospitalizations in Georgia...