Delia Bethell

Summary

Affiliation: Armed Forces Research Institute of Medical Sciences
Country: Thailand

Publications

  1. pmc Evaluation of parasite subpopulations and genetic diversity of the msp1, msp2 and glurp genes during and following artesunate monotherapy treatment of Plasmodium falciparum malaria in Western Cambodia
    Panita Gosi
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science AFRIMS, Bangkok, Thailand
    Malar J 12:403. 2013
  2. pmc Evaluation of in vitro cross-reactivity to avian H5N1 and pandemic H1N1 2009 influenza following prime boost regimens of seasonal influenza vaccination in healthy human subjects: a randomised trial
    Delia Bethell
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 8:e59674. 2013
  3. pmc Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments
    Mark M Fukuda
    Armed Forces Health Surveillance Center, 2900 Linden Lane, Silver Spring, MD 20910, USA
    BMC Public Health 11:S9. 2011
  4. doi request reprint Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria
    Delia Bethell
    Dept of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bagkok, Thailand
    Clin Infect Dis 51:e105-14. 2010
  5. pmc Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial
    Delia Bethell
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 6:e19283. 2011
  6. pmc Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates
    Wiriya Rutvisuttinunt
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok, Thailand
    Malar J 11:325. 2012
  7. pmc Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia
    David Saunders
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences AFRIMS, Bangkok, Thailand
    Antimicrob Agents Chemother 56:5484-93. 2012
  8. pmc Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay
    Stuart D Tyner
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Malar J 11:198. 2012
  9. pmc Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open-label randomized trial
    Chanthap Lon
    US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Department of Immunology and Medicine, Bangkok, Thailand US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Phnom Penh, Cambodia
    PLoS ONE 9:e93138. 2014
  10. pmc Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006-2009
    Chanthap Lon
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    Malar J 12:217. 2013

Collaborators

Detail Information

Publications12

  1. pmc Evaluation of parasite subpopulations and genetic diversity of the msp1, msp2 and glurp genes during and following artesunate monotherapy treatment of Plasmodium falciparum malaria in Western Cambodia
    Panita Gosi
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Science AFRIMS, Bangkok, Thailand
    Malar J 12:403. 2013
    ..An additional objective was to investigate whether the classification of clinical outcomes remained valid when additional genotyping was performed...
  2. pmc Evaluation of in vitro cross-reactivity to avian H5N1 and pandemic H1N1 2009 influenza following prime boost regimens of seasonal influenza vaccination in healthy human subjects: a randomised trial
    Delia Bethell
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 8:e59674. 2013
    ....
  3. pmc Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments
    Mark M Fukuda
    Armed Forces Health Surveillance Center, 2900 Linden Lane, Silver Spring, MD 20910, USA
    BMC Public Health 11:S9. 2011
    ..This review describes recent VBI-related epidemiological studies conducted by AFHSC-GEIS partner laboratories within the OCONUS DoD laboratory network emphasizing their impact on human populations...
  4. doi request reprint Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria
    Delia Bethell
    Dept of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bagkok, Thailand
    Clin Infect Dis 51:e105-14. 2010
    ..Fears of emerging artemisinin resistance in western Cambodia have prompted a series of clinical trials investigating whether slow responses to antimalarial treatment can be overcome by increasing doses of drug...
  5. pmc Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial
    Delia Bethell
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 6:e19283. 2011
    ..This study investigated the impact of different AS doses on clinical and parasitological responses in malaria patients from an area of known artemisinin resistance in western Cambodia...
  6. pmc Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates
    Wiriya Rutvisuttinunt
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok, Thailand
    Malar J 11:325. 2012
    ..Although in vitro anti-malarial susceptibility tests are widely used, uncertainties remain regarding interpretation of P. falciparum field isolate values...
  7. pmc Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia
    David Saunders
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences AFRIMS, Bangkok, Thailand
    Antimicrob Agents Chemother 56:5484-93. 2012
    ..While direct concentration-effect relationships were not found, it remains possible that a population PK modeling approach that allows modeling of greater dose separation might discern more-subtle relationships...
  8. pmc Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay
    Stuart D Tyner
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Malar J 11:198. 2012
    ....
  9. pmc Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open-label randomized trial
    Chanthap Lon
    US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Department of Immunology and Medicine, Bangkok, Thailand US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Phnom Penh, Cambodia
    PLoS ONE 9:e93138. 2014
    ..We compared two regimens of dihydroartemisinin-piperaquine in military and civilians on the Thai-Cambodian border to evaluate national treatment policy...
  10. pmc Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006-2009
    Chanthap Lon
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, 315 6 Rajvithi Road, Bangkok 10400, Thailand
    Malar J 12:217. 2013
    ..Little has been reported in the peer-reviewed literature regarding the burden of severe malaria (SM) in Cambodia...
  11. pmc Plasmodium falciparum gametocyte carriage is associated with subsequent Plasmodium vivax relapse after treatment
    Jessica T Lin
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 6:e18716. 2011
    ..vivax coinfection and subsequent relapse. These patients may benefit from empiric treatment with an 8-aminoquinolone such as primaquine...
  12. pmc Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
    Arjen M Dondorp
    Mahidol Oxford Tropical Medicine Research Unit MORU, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Lancet 376:1647-57. 2010
    ..We compared parenteral treatment with either artesunate or quinine in African children with severe malaria...