John V Terrovitis

Summary

Publications

  1. ncbi request reprint Hemodynamic effects of levosimendan added to dobutamine in patients with decompensated advanced heart failure refractory to dobutamine alone
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Am J Cardiol 94:1329-32. 2004
  2. doi request reprint Elevated left ventricular filling pressures can be estimated with accuracy by a new mathematical model
    John V Terrovitis
    Third Department of Cardiology, University of Athens School of Medicine, Athens, Greece
    J Heart Lung Transplant 32:511-7. 2013
  3. doi request reprint Anemia in heart failure: pathophysiologic insights and treatment options
    John V Terrovitis
    3rd Cardiology Department, University of Athens, School of Medicine, Athens, Greece
    Future Cardiol 5:71-81. 2009
  4. ncbi request reprint Out-patient management of chronic heart failure
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Harefield, UK
    Expert Opin Pharmacother 6:1857-81. 2005
  5. ncbi request reprint Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Imperial College, London, United Kingdom
    Tissue Eng 12:2765-75. 2006
  6. doi request reprint Increase in coronary blood flow by intra-aortic balloon counterpulsation in a porcine model of myocardial reperfusion
    Michael J Bonios
    3rd Department of Cardiology, University of Athens School of Medicine, Athens, Greece
    Int J Cardiol 138:253-60. 2010
  7. ncbi request reprint Efficacy and safety of intermittent, long-term, concomitant dobutamine and levosimendan infusions in severe heart failure refractory to dobutamine alone
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Am J Cardiol 95:768-71. 2005
  8. ncbi request reprint Reverse left ventricular remodeling by intermittent dobutamine infusions and amiodarone in end-stage heart failure due to idiopathic dilated cardiomyopathy
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Int J Cardiol 108:237-43. 2006
  9. doi request reprint Mechanical assistance by intra-aortic balloon pump counterpulsation during reperfusion increases coronary blood flow and mitigates the no-reflow phenomenon: an experimental study
    Charalampos N Pierrakos
    3rd Department of Cardiology, University of Athens School of Medicine, Greece
    Artif Organs 35:867-74. 2011
  10. ncbi request reprint Comparison of pulsatile with nonpulsatile mechanical support in a porcine model of profound cardiogenic shock
    Stavros G Drakos
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    ASAIO J 51:26-9. 2005

Collaborators

  • Stavros G Drakos
  • Maria Anastasiou-Nana
  • Magdi H Yacoub
  • Efstratios I Charitos
  • David N Firmin
  • Eduardo Marban
  • Eleftherios Sachlos
  • Patricia M Taylor
  • Eirini Grapsa
  • Adrian H Chester
  • Lindsey A Crowe
  • Puspa Batten
  • JEFF BULTE
  • John N Nanas
  • Eleftheria P Tsagalou
  • Michael J Bonios
  • Charalampos N Pierrakos
  • Serafim N Nanas
  • John Kanakakis
  • Chris J Kapelios
  • George P Alexopoulos
  • Argirios Ntalianis
  • Christos E Charitos
  • Elias J Tsolakis
  • Elias Tsolakis
  • Argirios Dalianis
  • Elisabet E Kaldara-Papatheodorou
  • Paraskevi Dolou
  • Konstantinos G Malliaras
  • Panagiotis Papazoglou
  • Argyrios S Ntalianis
  • Christos Charitos
  • Savas Toumanidis
  • Panagiotis Siskas
  • Christos Kontogiannis
  • Evangelos Repasos
  • Nikolaos Lazaris
  • Nikolaos Diakos
  • Konstantinos Malliaras
  • Iraklis A Pozios
  • Apostolos Papalois
  • John Venetsanakos
  • George Alexopoulos
  • Chris Pantsios
  • Savvas Toumanidis
  • Fotis Katsaros
  • Elisavet Kaldara
  • Dimitrios Koudoumas
  • Michael Argiriou
  • Elisabeth E Kaldara
  • Fotios T Katsaros
  • Pantelis Gounopoulos
  • Emmanuel Agapitos
  • Apostolia Gika
  • Theodoros Papaioannou
  • Panagiotis D Papazoglou
  • Seraphim N Nanas
  • Ageliki Eleftheriou
  • Costantinos X Siafakas
  • Thomas Moon
  • Emmanuel M Mavrikakis
  • Antonios Doufas
  • Panagiotis P Papazoglou
  • Christos Kassiotis
  • Zafiria Margari
  • Kostantinos Christodoulou
  • Ourania Papazachou
  • Nikolaos Agrios
  • Stamatina Makri
  • Ageliki Ch Rapti
  • Zafiria J Margari
  • Dimitrios Mitsibounas

Detail Information

Publications44

  1. ncbi request reprint Hemodynamic effects of levosimendan added to dobutamine in patients with decompensated advanced heart failure refractory to dobutamine alone
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Am J Cardiol 94:1329-32. 2004
    ..002) mean decrease in pulmonary capillary wedge pressure compared with measurements obtained after 24 hours of dobutamine infusion alone. Symptoms were alleviated in all patients, and all but 3 were discharged from the hospital...
  2. doi request reprint Elevated left ventricular filling pressures can be estimated with accuracy by a new mathematical model
    John V Terrovitis
    Third Department of Cardiology, University of Athens School of Medicine, Athens, Greece
    J Heart Lung Transplant 32:511-7. 2013
    ....
  3. doi request reprint Anemia in heart failure: pathophysiologic insights and treatment options
    John V Terrovitis
    3rd Cardiology Department, University of Athens, School of Medicine, Athens, Greece
    Future Cardiol 5:71-81. 2009
    ..In this review, the recent advances in elucidating the mechanisms leading to anemia in the setting of heart failure are presented and the evidence supporting the use of different treatment approaches are discussed...
  4. ncbi request reprint Out-patient management of chronic heart failure
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Harefield, UK
    Expert Opin Pharmacother 6:1857-81. 2005
    ....
  5. ncbi request reprint Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Imperial College, London, United Kingdom
    Tissue Eng 12:2765-75. 2006
    ..Ferumoxide labeling of human MSCs seeded on collagen scaffolds is an effective, non-toxic technique for visualization of these cells using MRI. This technique appears promising for cell tracking in future tissue-engineering applications...
  6. doi request reprint Increase in coronary blood flow by intra-aortic balloon counterpulsation in a porcine model of myocardial reperfusion
    Michael J Bonios
    3rd Department of Cardiology, University of Athens School of Medicine, Athens, Greece
    Int J Cardiol 138:253-60. 2010
    ..The purpose of the present study was to measure the changes in coronary blood flow induced by intra-aortic balloon pump (IABP) counterpulsation in normal and reperfused porcine myocardium...
  7. ncbi request reprint Efficacy and safety of intermittent, long-term, concomitant dobutamine and levosimendan infusions in severe heart failure refractory to dobutamine alone
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Am J Cardiol 95:768-71. 2005
    ..0002, log-rank test)...
  8. ncbi request reprint Reverse left ventricular remodeling by intermittent dobutamine infusions and amiodarone in end-stage heart failure due to idiopathic dilated cardiomyopathy
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Int J Cardiol 108:237-43. 2006
    ....
  9. doi request reprint Mechanical assistance by intra-aortic balloon pump counterpulsation during reperfusion increases coronary blood flow and mitigates the no-reflow phenomenon: an experimental study
    Charalampos N Pierrakos
    3rd Department of Cardiology, University of Athens School of Medicine, Greece
    Artif Organs 35:867-74. 2011
    ..After prolonged myocardial ischemia, IABP assistance started just 10 min before and throughout reperfusion increased CBF and limited infarct size and extent of NRP...
  10. ncbi request reprint Comparison of pulsatile with nonpulsatile mechanical support in a porcine model of profound cardiogenic shock
    Stavros G Drakos
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    ASAIO J 51:26-9. 2005
    ..003), and left anterior descending artery flow from 26 +/- 10 to 39 +/- 14 ml/min (p = 0.001). In profound CS, mechanical support provided by a continuous flow CP is enhanced by the added pulsatility of the IABP...
  11. ncbi request reprint Prevalence and prognostic significance of anemia in patients with congestive heart failure treated with standard vs high doses of enalapril
    John V Terrovitis
    Heart Science Centre Harefield Hospital, Harefield, Middlesex, UK
    J Heart Lung Transplant 25:333-8. 2006
    ..The purpose of this study was to examine the prognostic significance of a low hematocrit (Hct) in patients with CHF and the possible role of angiotensin-converting enzyme inhibition in anemia development...
  12. ncbi request reprint Myocardial ischaemic preconditioning in the pig has no effect on the ventricular fibrillation and defibrillation thresholds
    Maria I Anastasiou-Nana
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Makedonias 24, 104 33 Athens, Greece
    Resuscitation 64:373-6. 2005
    ..This study examined the time course of changes in ventricular fibrillation (VFT) and defibrillation (DFT) thresholds during transient myocardial ischaemia after a 45 min preconditioning period...
  13. doi request reprint Intra-aortic balloon counterpulsation and delayed revascularization for myocardial infarction and shock in the absence of primary angioplasty: a treatment strategy with or without thrombolysis?
    Stavros G Drakos
    University of Athens School of Medicine, 3rd Cardiology Department, Alexandra Hospital, Athens, Greece
    Coron Artery Dis 19:521-6. 2008
    ..The use of TT in this setting, however, remains controversial...
  14. doi request reprint Effects of L-NAME on coronary blood flow, infarct size and the extent of the no-reflow phenomenon
    Charalampos N Pierrakos
    3rd Department of Cardiology, University of Athens, Laiko Hospital, Athens, Greece
    Int J Cardiol 167:3000-5. 2013
    ..Despite hemodynamic efficacy, their effects on the extent of myocardial infarction (MI) and the no-reflow phenomenon (NRP) have not been clarified...
  15. ncbi request reprint Effects of transient myocardial ischemia on the ventricular defibrillation threshold
    Maria I Anastasiou-Nana
    Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
    Pacing Clin Electrophysiol 28:97-101. 2005
    ..Acute myocardial ischemia and the mode of ventricular fibrillation (VF) induction influence the ventricular defibrillation threshold (DFT)...
  16. ncbi request reprint Amiodarone attenuates the proarrhythmic effects of dobutamine in patients with advanced congestive heart failure
    Eleftheria P Tsagalou
    3rd Cardiology Department, University of Athens School of Medicine, Athens, Greece
    Hellenic J Cardiol 50:193-8. 2009
    ..This study evaluated the effects of oral amiodarone on the arrhythmias caused by dobutamine in patients with advanced CHF...
  17. doi request reprint Depressed coronary flow reserve is associated with decreased myocardial capillary density in patients with heart failure due to idiopathic dilated cardiomyopathy
    Eleftheria P Tsagalou
    Third Cardiology Department, University of Athens School of Medicine, Athens, Greece
    J Am Coll Cardiol 52:1391-8. 2008
    ..We sought to examine the relationship between coronary flow reserve (CFR) and myocardial capillary density (MCD) in patients with idiopathic dilated cardiomyopathy, heart failure, and normal coronary arteries...
  18. doi request reprint Effects of intra-aortic balloon pump versus centrifugal pump on myocardial energetics and systemic circulation in a porcine model of rapidly worsening acute heart failure
    Argyrios S Ntalianis
    3rd Cardiology Department of University of Athens School of Medicine, Athens, Greece
    ASAIO J 54:600-5. 2008
    ..However, afterload reduction offered principally by the IABP seems preferable for the recovery of the acutely failing heart...
  19. doi request reprint Myocardial sympathetic innervation and long-term left ventricular mechanical unloading
    Stavros G Drakos
    3rd Cardiology Department, University of Athens, and Division of Nuclear Medicine, Alexandra Hospital, Athens, Greece
    JACC Cardiovasc Imaging 3:64-70. 2010
    ..The purpose of this study was to analyze the effects of left ventricular assist devices (LVADs) on myocardial sympathetic innervation of the failing heart...
  20. doi request reprint Long-term survival and outcomes after hospitalization for acute myocardial infarction complicated by cardiogenic shock
    Stavros G Drakos
    Third Cardiology Department, University of Athens School of Medicine, Athens, Greece
    Clin Cardiol 32:E4-8. 2009
    ..However, little data exist regarding the long-term outcomes of patients who survived the acute phase of MI and were discharged from the hospital...
  21. ncbi request reprint Ventilatory response to exercise and kinetics of oxygen recovery are similar in cardiac transplant recipients and patients with mild chronic heart failure
    Serafim N Nanas
    Pulmonary and Critical Care Medicine Department, National and Kapodestrian University, Athens, Greece
    J Heart Lung Transplant 23:1154-9. 2004
    ..This study evaluated the ventilatory response to exercise and the kinetics of oxygen (O(2)) recovery in heart transplant recipients (HTR) compared to healthy volunteers (HV) and heart failure patients...
  22. doi request reprint Reverse electrophysiologic remodeling after cardiac mechanical unloading for end-stage nonischemic cardiomyopathy
    Stavros G Drakos
    Third Cardiology Department, University of Athens, Athens, Greece
    Ann Thorac Surg 91:764-9. 2011
    ..However, its effect on arrhythmogenicity is a controversial issue, and prospective data are lacking. We sought to investigate the impact of LVAD-induced unloading on the electrical properties of the failing heart...
  23. ncbi request reprint Lowering of furosemide dosage after clinical stabilization in patients with congestive heart failure
    George P Alexopoulos
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Acta Cardiol 58:513-7. 2003
    ..This study was performed to examine the safety of reducing the long-term doses of furosemide administered to patients with congestive heart failure (CHF) stabilized on a standard medical treatment...
  24. ncbi request reprint Time course of fibrillation and defibrillation thresholds after an intravenous bolus of amiodarone--an experimental study
    Eleftheria P Tsagalou
    Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, Makedonias 24, 104 33 Athens, Greece
    Resuscitation 61:83-9. 2004
    ..The aim of this study was to examine the early time course of changes in VFT and defibrillation thresholds (DFT) after an intravenous bolus of amiodarone in an experimental pig model of transient myocardial ischemia...
  25. doi request reprint Reverse cardiac remodeling enabled by mechanical unloading of the left ventricle
    Konstantinos G Malliaras
    Third Cardiology Department, University of Athens, Athens, Greece
    J Cardiovasc Transl Res 2:114-25. 2009
    ....
  26. ncbi request reprint Prognostic value of iodine-123-metaiodobenzylguanidine myocardial uptake and heart rate variability in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    Maria I Anastasiou-Nana
    Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
    Am J Cardiol 96:427-31. 2005
    ..310, 95% CI 0.101 to 0.954, p = 0.041) but not with all-cause mortality. In conclusion, cardiac I-123-MIBG imaging identifies patients with CHF at high risk of dying and may be a more reliable predictor of overall mortality than HRV...
  27. ncbi request reprint Long-term intermittent dobutamine infusion, combined with oral amiodarone for end-stage heart failure: a randomized double-blind study
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Chest 125:1198-204. 2004
    ..To examine the effects of long-term intermittent dobutamine infusion, combined with oral amiodarone in patients with congestive heart failure (CHF) refractory to standard medical treatment...
  28. ncbi request reprint Reverse remodeling during long-term mechanical unloading of the left ventricle
    Stavros G Drakos
    3rd Cardiology Department, University of Athens School of Medicine, 24 Makedonias, 104 33, Athens, Greece
    J Mol Cell Cardiol 43:231-42. 2007
    ..In addition, this kind of information will enable changes in the strategy of myocardial recovery by modifying the duration and scale of the unloading regimen or by combining it with other treatments that promote reverse remodeling...
  29. doi request reprint Comparison of three different regimens of intermittent inotrope infusions for end stage heart failure
    Michael J Bonios
    3rd Cardiology Department, University of Athens Medical School, Athens, Greece
    Int J Cardiol 159:225-9. 2012
    ..The aim of the study was to compare the effect of levosimendan versus dobutamine, alone or in combination with levosimendan, on the outcome of end-stage heart failure patients, requiring inotropic therapy...
  30. doi request reprint The challenge of treating congestion in advanced heart failure
    Michael J Bonios
    The Third Cardiology Department, University of Athens, Medical School, 67 M Asias Street, Athens, Greece
    Expert Rev Cardiovasc Ther 9:1181-91. 2011
    ....
  31. ncbi request reprint Ultrafiltration in the treatment of severe congestive heart failure
    Eirini Grapsa
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Int Urol Nephrol 36:269-72. 2004
    ..Vacuum ultrafiltration, hemodialysis, or a combination of both was used in patients with severe CHF (NYHA class IV), severe edema, and insensitivity to pharmacological treatment with diuretics...
  32. ncbi request reprint Moderate systemic hypotension during reperfusion reduces the coronary blood flow and increases the size of myocardial infarction in pigs
    John N Nanas
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Chest 125:1492-9. 2004
    ..s: To examine the effects of low arterial BP (ABP) during reperfusion on the extent of myocardial infarction and on coronary blood flow (CBF) in an occlusion/reperfusion experimental model...
  33. ncbi request reprint Spontaneous coronary artery dissection as a cause of acute myocardial infarction in the postpartum period
    John V Terrovitis
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Cardiol Rev 13:211-3. 2005
    ..The patient's in-hospital and long-term clinical course and prognosis are described and the potential pathogenetic mechanisms are discussed. Finally, the treatment options for this rare entity are presented...
  34. pmc Assessment and optimization of cell engraftment after transplantation into the heart
    John V Terrovitis
    Third Department of Cardiology, University of Athens, Greece
    Circ Res 106:479-94. 2010
    ....
  35. ncbi request reprint Counterpulsation: a concept with a remarkable past, an established present and a challenging future
    Chris J Kapelios
    3rd Department of Cardiology, University of Athens School of Medicine, Greece
    Int J Cardiol 172:318-25. 2014
    ..Despite the fact that several other counterpulsation devices have been developed and tested overtime none has managed to substitute the IABP, which continues to be most frequently used mechanical assist device. ..
  36. ncbi request reprint Current and future applications of the intra-aortic balloon pump
    Chris J Kapelios
    The 3rd Department of Cardiology, University of Athens School of Medicine, Athens, Greece
    Curr Opin Cardiol 29:258-65. 2014
    ..This review focuses on studies challenging these traditional indications and evaluates potentially new applications of intra-aortic counterpulsation...
  37. ncbi request reprint Effectiveness of amiodarone therapy in patients with severe congestive heart failure and intolerance to metoprolol
    Maria I Anastasiou-Nana
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Am J Cardiol 90:1017-9. 2002
  38. ncbi request reprint Delayed complete recovery of graft dysfunction after cardiac transplantation
    John V Terrovitis
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    J Card Surg 18:29-31. 2003
    ..In addition to the case presented, potential contributing factors to this syndrome, together with appropriate treatment options, are discussed...
  39. ncbi request reprint Anemia in heart failure: should we supplement iron in patients with chronic heart failure?
    Elisabet E Kaldara-Papatheodorou
    3rd Cardiology Department, University of Athens, School of Medicine, Greece
    Pol Arch Med Wewn 120:354-60. 2010
    ..The superiority of any of these approaches has not been established yet. This review will discuss different treatment options for anemic patients with CHF, with emphasis on the correction of iron deficiency...
  40. ncbi request reprint Hemophagocytic lymphohistiocytosis after chemotherapy for multiple myeloma
    John V Terrovitis
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, Greece
    Clin Lymphoma 5:194-6. 2004
    ..We report a case of secondary hemophagocytic syndrome after chemotherapy for multiple myeloma, which responded dramatically to dexamethasone, etoposide, and cyclosporin A...
  41. ncbi request reprint Superior performance of a paraaortic counterpulsation device compared to the intraaortic balloon pump
    John V Terrovitis
    University of Athens School of Medicine, Department of Clinical Therapeutics, Alexandra Hospital, 80 Vas Sofias Av and K Lourou, 115 28, Athens, Greece
    World J Surg 27:1311-6. 2003
    ..The simplicity of its implantation, together with the ability of the standard IABP consoles to control its function, make it a promising device for mechanical assistance of the failing heart...
  42. ncbi request reprint The long-term survival benefit conferred by intermittent dobutamine infusions and oral amiodarone is greater in patients with idiopathic dilated cardiomyopathy than with ischemic heart disease
    Eleftheria P Tsagalou
    University Vita Salute San Raffaele, Milano, Italy
    Int J Cardiol 108:244-50. 2006
    ..The purpose of the present study was to evaluate whether the response to long-term treatment with IDI+amiodarone is different in patients with ischemic heart disease (IHD) versus idiopathic dilated cardiomyopathy (IDC)...