Research Topics

Mariana Teles



  1. Vargas R, Balasch J, Brandts I, Reyes Lopez F, Tort L, Teles M. Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine. Sci Rep. 2018;8:17352 pubmed publisher
    ..Results also indicate that under bath vaccination proactive fish show high immune response and lower metabolism, whereas reactive fish show low immune and higher metabolic responses. ..
  2. Na Phatthalung P, Teles M, Tort L, Oliveira M. Gold nanoparticles exposure modulates antioxidant and innate immune gene expression in the gills of Sparus aurata. Genomics. 2018;110:430-434 pubmed publisher
    ..Results indicate that AuNPs with distinct coatings induced different gene expression profiles in gills, though most of the studied genes remained unaltered for the tested conditions. ..
  3. Brandts I, Teles M, Tvarijonaviciute A, Pereira M, Martins M, Tort L, et al. Effects of polymethylmethacrylate nanoplastics on Dicentrarchus labrax. Genomics. 2018;110:435-441 pubmed publisher
    ..The present results suggest that NPs may represent a hazard to this marine fish, potentially interfering with the metabolism of lipids and the correct function of the immune response. ..
  4. Na Phatthalung P, Teles M, Voravuthikunchai S, Tort L, Fierro Castro C. Immune-related gene expression and physiological responses in rainbow trout (Oncorhynchus mykiss) after intraperitoneal administration of Rhodomyrtus tomentosa leaf extract: A potent phytoimmunostimulant. Fish Shellfish Immunol. 2018;77:429-437 pubmed publisher
    ..Our observations suggest that R. tomentosa induced the expression of genes involved in cytokine and innate immune response and modulated the physiological stress response as indicated by the suppressed cortisol in rainbow trout. ..
  5. Brandts I, Teles M, Goncalves A, Barreto A, Franco Martinez L, Tvarijonaviciute A, et al. Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine. Sci Total Environ. 2018;643:775-784 pubmed publisher
    ..05?mg?L-1 PS exposure, showing that nanoplastics can induce oxidative damage. The present study demonstrated that PS, even at low concentrations, led to alterations on the assessed mussels' endpoints. ..
  6. Teles M, Reyes López F, Fierro Castro C, Tort L, Soares A, Oliveira M. Modulation of immune genes mRNA levels in mucosal tissues and DNA damage in red blood cells of Sparus aurata by gold nanoparticles. Mar Pollut Bull. 2018;133:428-435 pubmed publisher
    ..Genotoxic potential of AuNP was demonstrated by increased DNA strand breaks in red blood cells of fish exposed to AuNP, suggesting that AuNP represent a potential hazard to fish. ..
  7. Albarracín V, Teles M, Meléndez Lazo A, Rodón J, Pastor J. Canine Pancreas-Specific Lipase and C-reactive Protein in Dogs Treated With Anticonvulsants (Phenobarbital and Potassium Bromide). Top Companion Anim Med. 2015;30:57-61 pubmed publisher
    ..It may be induced by the anticonvulsants drugs; however, further studies are advised to rule out other possible causes that increased cPLI. ..
  8. Teles M, Fierro Castro C, Na Phatthalung P, Tvarijonaviciute A, Soares A, Tort L, et al. Evaluation of gemfibrozil effects on a marine fish (Sparus aurata) combining gene expression with conventional endocrine and biochemical endpoints. J Hazard Mater. 2016;318:600-607 pubmed publisher
    ..aurata. Cortisol levels and the mRNA levels of il1β, tnfα and casp3 may be suggested as potential biomarkers of GEM effects in marine fish. ..
  9. Teles M, Boltaña S, Reyes Lopez F, Santos M, MacKenzie S, Tort L. Effects of chronic cortisol administration on global expression of GR and the liver transcriptome in Sparus aurata. Mar Biotechnol (NY). 2013;15:104-14 pubmed publisher
    ..Transcriptional remodeling highlighted a significant activity in carbohydrate metabolism mainly in the gluconeogenic pathway linked to downregulation of inflammatory and immune response processes in implanted fish. ..

More Information


  1. Teles M, Fierro Castro C, Na Phatthalung P, Tvarijonaviciute A, Trindade T, Soares A, et al. Assessment of gold nanoparticle effects in a marine teleost (Sparus aurata) using molecular and biochemical biomarkers. Aquat Toxicol. 2016;177:125-35 pubmed publisher
    ..Another important finding is that effects are mainly induced by the lowest and intermediate concentrations of the PVP coated AuNP revealing the importance of different coatings. ..
  2. Boltaña S, Castellana B, Goetz G, Tort L, Teles M, Mulero V, et al. Extending Immunological Profiling in the Gilthead Sea Bream, Sparus aurata, by Enriched cDNA Library Analysis, Microarray Design and Initial Studies upon the Inflammatory Response to PAMPs. Int J Mol Sci. 2017;18: pubmed publisher
    ..We have developed and validated an oligonucleotide microarray (SAQ) that provides a platform enriched for the study of gene expression in S. aurata with an emphasis upon immunity and the immune response. ..
  3. Teles M, Soares A, Tort L, Guimaraes L, Oliveira M. Linking cortisol response with gene expression in fish exposed to gold nanoparticles. Sci Total Environ. 2017;584-585:1004-1011 pubmed publisher
    ..Unlike AuNP-citrate, AuNP-PVP elicited an inverted U-shaped response. Present findings demonstrated that AuNP were able to activate the fish HPI axis and alter a battery of related molecular markers in the head kidney. ..