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..In this review, we highlight novel pharmacological agents that hold promise for targeting wound repair and fibrosis. We also focus on drug-delivery systems that may enhance current and future therapies. ..
Kyrousi C, Arbi M, Pilz G, Pefani D, Lalioti M, Ninkovic J, et al
. Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 2015;142:3661-74 pubmed publisher
..Our results suggest that Mcidas and GemC1 are key players in the generation of multiciliated ependymal cells of the adult neurogenic niche. ..
Stathopoulou A, Natarajan D, Nikolopoulou P, Patmanidi A, Lygerou Z, Pachnis V, et al
. Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. Dev Biol. 2016;409:392-405 pubmed publisher
..Our results suggest that Geminin is an important regulator of self-renewal and survival of enteric nervous system progenitor cells. ..
Konstantinidou C, Taraviras S, Pachnis V. Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis. BMC Biol. 2016;14:94 pubmed
..These studies suggest that the microenvironment of the embryonic gut protects ENS progenitors and their progeny from genotoxic stress. ..