Estrogens and environmental estrogensH Tapiero
Laboratoire de Pharmacologie Cellulaire and Moléculaire, CNRS UMR 8612, Universite de Paris Sud, Faculte de Pharmacie, Chatenay Malabry, France
Biomed Pharmacother 56:36-44. 2002
..Thus, depending on the natural estrogen levels, environmental estrogens may have different influences (mimicking, blocking or cancelling out estrogen's effects) on estrogen activities...
- Trace elements in human physiology and pathology: zinc and metallothioneins
Haim Tapiero
Université de Paris Faculté de Pharmacie CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200, Chatenay Malabry, France
Biomed Pharmacother 57:399-411. 2003
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- Organosulfur compounds from alliaceae in the prevention of human pathologies
Haim Tapiero
Université de Paris Faculté de Pharmacie CNRS UMR 8612, Chatenay Malabry, France
Biomed Pharmacother 58:183-93. 2004
..Furthermore, OSC bioactivities include antioxidant, antibacterial, anticarcinogenic, antiatherogenic, immunostimulatory, and liver protection potential...
- The role of carotenoids in the prevention of human pathologies
H Tapiero
Université de Paris Faculté de Pharmacie CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200 Chatenay Malabry, France
Biomed Pharmacother 58:100-10. 2004
..Gap junctional communication between cells which may be a basis for protection against cancer development is independent of the antioxidant property...
- Trace elements in human physiology and pathology. Copper
H Tapiero
Université de Paris Faculté de Pharmacie CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200, Chatenay Malabry, France
Biomed Pharmacother 57:386-98. 2003
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- Phytosterols in the prevention of human pathologies
H Tapiero
Faculte de Pharmacie, UNIVERSITE DE PARIS, CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200 Chatenay Malabry, France
Biomed Pharmacother 57:321-5. 2003
..In addition, phytosterols may influence cell growth and apoptosis of tumor cells. However, they can interfere with the absorption of fat soluble vitamins and carotenoids...
- The antioxidant role of selenium and seleno-compounds
H Tapiero
Université de Paris Faculté de Pharmacie, CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200, Chatenay Malabry, France
Biomed Pharmacother 57:134-44. 2003
..In contrast, in cells treated with methylselenocyanate or Se methylselenocysteine, the cell cycle progression was blocked at the G(1) phase and cell death was predominantly induced by apoptosis...
- II. Glutamine and glutamate
H Tapiero
Faculte de Pharmacie, UNIVERSITE DE PARIS, CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200 Chatenay Malabry, France
Biomed Pharmacother 56:446-57. 2002
..Our aim here is to review on some amino acids with high functional priority such as glutamine and to define their effective activity in human health and pathologies...
- I. Arginine
H Tapiero
Faculte de Pharmacie, UNIVERSITE DE PARIS, CNRS UMR 8612, 5, rue Jean Baptiste Clement, 94200 Chatenay Malabry, France
Biomed Pharmacother 56:439-45. 2002
..Our aim here is to review on some amino acids with high functional priority such as Arg and to define their effective activity in human health and pathologies...
- Polyunsaturated fatty acids (PUFA) and eicosanoids in human health and pathologies
H Tapiero
UNIVERSITE DE PARIS, Faculté de Pharmacie CNRS UMR 8612, Chatenay Malabry, France
Biomed Pharmacother 56:215-22. 2002
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- Polyphenols: do they play a role in the prevention of human pathologies?
H Tapiero
Faculte de Pharmacie, UNIVERSITE DE PARIS, CNRS UMR, Chatenay Malabry, France
Biomed Pharmacother 56:200-7. 2002
..It is, therefore, essential to know the nature of the main polyphenols ingested, their dietary origin, the amounts consumed in different diets, their bioavailability and the factors controlling their bioavailability...
- Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements
H Tapiero
Laboratoire de Pharmacologie Cellulaire et Moleculaire, CNRS UMR 8612, Universite de Paris Sud, Faculte de Pharmacie, Chatenay Malabry, France
Biomed Pharmacother 55:381-90. 2001
..The supply of folate depends primarily on the quantity and bioavailability of ingested folate and the rate of loss by urinary and fecal routes and through catabolism...
- Iron: deficiencies and requirements
H Tapiero
Laboratoire de Pharmacologie Cellulaire and Moléculaire, Universite de Paris Sud, Faculte de Pharmacie, Chatenay Malabry, France
Biomed Pharmacother 55:324-32. 2001
..The administration of iron supplements weekly instead of daily in humans has been proposed and is being actively investigated as a viable means of controlling iron deficiency in populations, including pregnant women...
- The antioxidant effects of Crassostrea gigas extract (JCOE) in human volunteers
H Tapiero
Department of Pharmacology, CNRS URA 1218, Faculty of Pharmacy, Chatenay Malabry, France
In Vivo 12:305-9. 1998
..While the extract is known to contain some direct acting antioxidant components, at least a portion of the protective effect is facilitated by enhancement of GSH biosynthesis...
- The importance of glutathione in human disease
Danyelle M Townsend
Department of Pharmacology, Fox Chase Cancer Center, 7701 Burholme Ave, Philadelphia, PA 19111, USA
Biomed Pharmacother 57:145-55. 2003
..Polymorphic expression of enzymes involved in GSH homeostasis influences susceptibility and progression of these conditions. This review provides an overview of the biological importance of GSH at the level of the cell and organism...
- Influence of alcohol consumption and smoking habits on human health
Haim Tapiero
Biomed Pharmacother 58:75-6. 2004
- Sulfur containing amino acids and human disease
Danyelle M Townsend
Department of Pharmacology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Biomed Pharmacother 58:47-55. 2004
..In addition, thiol imbalance has been associated with multiple disorders, including vascular disease, Alzheimer's, HIV and cancer. Possible treatments to restore the thiol balance are also discussed...
- Sulfiredoxin: a potential therapeutic agent?
Victoria J Findlay
Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC 29425, USA
Biomed Pharmacother 59:374-9. 2005
..This review discusses Srx as a novel antioxidant, and focuses on its potential role in the regulation of glutathionylation/deglutathionylation pathways, that have been implicated in a growing number of disease states...
