M J Moshi

Summary

Affiliation: Muhimbili University College of Health Sciences
Country: Tanzania

Publications

  1. ncbi request reprint Antimicrobial and brine shrimp toxicity of some plants used in traditional medicine in Bukoba District, north-western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P O Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 11:23-8. 2009
  2. pmc Experience of initiating collaboration of traditional healers in managing HIV and AIDS in Tanzania
    Edmund J Kayombo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, PO Box 65001, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 3:6. 2007
  3. pmc Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis
    Omar J M Hamza
    Department of Oral Surgery and Oral Pathology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Microbiol 8:135. 2008
  4. pmc Antimicrobial activity and brine shrimp toxicity of extracts of Terminalia brownii roots and stem
    Zakaria H Mbwambo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    BMC Complement Altern Med 7:9. 2007
  5. ncbi request reprint Current and future prospects of integrating traditional and alternative medicine in the management of diseases in Tanzania
    M J Moshi
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Tanzan Health Res Bull 7:159-67. 2005
  6. ncbi request reprint Plants used to treat epilepsy by Tanzanian traditional healers
    Mainen J Moshi
    Department of Pharmacology and Toxicology, Institute of Traditional Medicine, Muhimbili University College of Health Sciences, P O Box 65001, Dar es Salaam, Tanzania
    J Ethnopharmacol 97:327-36. 2005
  7. ncbi request reprint Some pharmacological properties of extracts of Terminalia sericea roots
    M J Moshi
    Department of Pharmacology and Toxicology, Institute of Traditional Medicine, Muhimbili University College of Health Sciences, MUCHS, P O Box 65001, Dar es Salaam, Tanzania
    J Ethnopharmacol 97:43-7. 2005
  8. pmc The ethnomedicine of the Haya people of Bugabo ward, Kagera Region, north western Tanzania
    Mainen J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, MUHAS, P, O, Box 65001, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 5:24. 2009
  9. ncbi request reprint The effect of Phyllanthus amarus aqueous extract on blood glucose in non-insulin dependent diabetic patients
    M J Moshi
    Institute of Traditional Medicine, MUCHS, Box 65001, Dar es Salaam, Tanzania
    Phytother Res 15:577-80. 2001
  10. ncbi request reprint Brine shrimp toxicity of some plants used as traditional medicines in Kagera Region, north western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 12:63-7. 2010

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Antimicrobial and brine shrimp toxicity of some plants used in traditional medicine in Bukoba District, north-western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P O Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 11:23-8. 2009
    ..The seemingly innocuous nature and relatively good antibacterial activity against skin infections and gastrointestinal pathogenic bacteria support the traditional uses of the plants and deserve more detailed studies...
  2. pmc Experience of initiating collaboration of traditional healers in managing HIV and AIDS in Tanzania
    Edmund J Kayombo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, PO Box 65001, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 3:6. 2007
    ....
  3. pmc Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis
    Omar J M Hamza
    Department of Oral Surgery and Oral Pathology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Microbiol 8:135. 2008
    ..In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis...
  4. pmc Antimicrobial activity and brine shrimp toxicity of extracts of Terminalia brownii roots and stem
    Zakaria H Mbwambo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    BMC Complement Altern Med 7:9. 2007
    ..There is a need to evaluate extracts of this plant in order to provide scientific proof for it's wide application in traditional medicine system...
  5. ncbi request reprint Current and future prospects of integrating traditional and alternative medicine in the management of diseases in Tanzania
    M J Moshi
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Tanzan Health Res Bull 7:159-67. 2005
    ....
  6. ncbi request reprint Plants used to treat epilepsy by Tanzanian traditional healers
    Mainen J Moshi
    Department of Pharmacology and Toxicology, Institute of Traditional Medicine, Muhimbili University College of Health Sciences, P O Box 65001, Dar es Salaam, Tanzania
    J Ethnopharmacol 97:327-36. 2005
    ..Biological testing of these plants, using different models of convulsions is, suggested...
  7. ncbi request reprint Some pharmacological properties of extracts of Terminalia sericea roots
    M J Moshi
    Department of Pharmacology and Toxicology, Institute of Traditional Medicine, Muhimbili University College of Health Sciences, MUCHS, P O Box 65001, Dar es Salaam, Tanzania
    J Ethnopharmacol 97:43-7. 2005
    ..4 (3.5-8.4) to 17.4 (11.4-26.5) microg/ml, while that of cyclophosphamide, a standard anticancer drug, was 16.3 (10.6-25.2) microg/ml. Further work is in progress to isolate and identify active compounds in the extracts...
  8. pmc The ethnomedicine of the Haya people of Bugabo ward, Kagera Region, north western Tanzania
    Mainen J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, MUHAS, P, O, Box 65001, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 5:24. 2009
    ..As an initiative in that direction, this study documented the knowledge on medicinal plant use by traditional healers of Bugabo Ward in Bukoba District...
  9. ncbi request reprint The effect of Phyllanthus amarus aqueous extract on blood glucose in non-insulin dependent diabetic patients
    M J Moshi
    Institute of Traditional Medicine, MUCHS, Box 65001, Dar es Salaam, Tanzania
    Phytother Res 15:577-80. 2001
    ..We conclude that 1 week treatment with the aqueous extract of Phyllanthus amarus was incapable of lowering both FBG and postprandial blood glucose in untreated NIDDM patients...
  10. ncbi request reprint Brine shrimp toxicity of some plants used as traditional medicines in Kagera Region, north western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 12:63-7. 2010
    ..Picralima nitida and Rubus rigidus extracts are mildly toxic, but by comparison have a remote possibility to yield active anticancer compounds...
  11. ncbi request reprint Antiparasitic activity of some xanthones and biflavonoids from the root bark of Garcinia livingstonei
    Zakaria H Mbwambo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    J Nat Prod 69:369-72. 2006
    ..The dimeric xanthone garcilivin A (4) showed a higher and nonselective antiparasitic activity and cytotoxicity (IC(50) 2.0 microM against MRC-5 cells) than its diastereoisomer garcilivin C (5) (IC(50) 52.3 microM)...
  12. ncbi request reprint Medicinal plants used by Tanzanian traditional healers in the management of Candida infections
    D K B Runyoro
    Department of Pharmacognosy, School of Pharmacy, Muhimbili University College of Health Sciences, P O Box 65013, Dar es Salaam, Tanzania
    J Ethnopharmacol 106:158-65. 2006
    ..The task that remains is to screen extracts prepared from these plants and perform a bioassay-guided fractionation of the active extracts so as to isolate the active compounds from these plants...
  13. ncbi request reprint Evaluation of the quality of amodiaquine and sulphadoxine/pyrimethamine tablets sold by private wholesale pharmacies in Dar Es Salaam Tanzania
    O M S Minzi
    Clinical Pharmacology Department, Faculty of Medicine, Muhimbili University College of Health Sciences MUCHS, Dar es Salaam, Tanzania
    J Clin Pharm Ther 28:117-22. 2003
    ..The aim of this work was to assess the quality of SP and AQ tablets marketed by wholesale pharmacies in Dar Es Salaam, Tanzania...
  14. ncbi request reprint A novel isoflavonoid from Millettia puguensis
    Modest C Kapingu
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Planta Med 72:1341-3. 2006
    ....
  15. ncbi request reprint Anthranoid compounds with antiprotozoal activity from Vismia orientalis
    Zakaria H Mbwambo
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Planta Med 70:706-10. 2004
    ..b. rhodesiense, L. donovani and P. falciparum were in the range of 10 to 50 micrograms/mL. None of the compounds showed antibacterial or antiviral (including also HIV) activity...
  16. ncbi request reprint Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections
    Omar J M Hamza
    Department of Oral Surgery and Oral Pathology, Muhimbili University College of Health Sciences, P O Box 65014, Dar es Salaam, Tanzania
    J Ethnopharmacol 108:124-32. 2006
    ..Usambarensis (Taub) Brenan, Cyphosterma hildebrandti (Gilg), Desc, Elaeodendron buchannanii (Lows), Acacia nilotica (L.) Wild ex Del, Jatropha multifida L., and Pteridium aquilinum (L.) Kuhn...
  17. ncbi request reprint Diterpenoids from the roots of Croton macrostachys
    M C Kapingu
    Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Phytochemistry 54:767-70. 2000
    ....
  18. pmc Ethnomedicine of the Kagera Region, north western Tanzania. Part 2: The medicinal plants used in Katoro Ward, Bukoba District
    Mainen J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 6:19. 2010
    ..This study, the second in an ongoing series, reports on the medicinal plant species used in Katoro ward, Bukoba District, and tries to use the literature to establish proof of the therapeutic claims...
  19. ncbi request reprint Comparative bioavailability of oral sugar-coated and plain formulation of chloroquine phosphate marketed in Tanzania
    G H Rimoy
    Department of Clinical Pharmacology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Trop Doct 32:15-7. 2002
    ..Failure of chloroquine phosphate in this country has already been declared by the Ministry of Health, and the potential contribution of poorly formulated products remains a subject of debate...
  20. pmc Screening of traditionally used plants for in vivo antimalarial activity in mice
    Esther Innocent
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    Afr J Tradit Complement Altern Med 6:163-7. 2009
    ..glomerata and M. floribunda were above 2400 mg/kg body wt, above which point solubility was a problem. All the tested extracts were innocuous to the mice, up to 2400 mg/kg body wt, suggesting they may be safe for short-term use...
  21. ncbi request reprint Mosquito larvicidal constituents from Lantana viburnoides sp viburnoides var kisi (A. rich) Verdc (Verbenaceae)
    Ester Innocent
    Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    J Vector Borne Dis 45:240-4. 2008
    ..Bioassay-guided fractionation and subtraction bioassays of the dichloromethane extract of the root barks were carried out in order to identify the bioactive components for controlling Anopheles gambiae s.s. mosquito larvae...
  22. doi request reprint Single-dose fluconazole versus standard 2-week therapy for oropharyngeal candidiasis in HIV-infected patients: a randomized, double-blind, double-dummy trial
    Omar J M Hamza
    Department of Oral Surgery and Oral Pathology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    Clin Infect Dis 47:1270-6. 2008
    ..We conducted a prospective, randomized, double-blind, placebo-controlled trial to compare the clinical and mycological responses, relapse rates, and safety of a single 750-mg dose and a 14-day course of treatment with fluconazole...
  23. doi request reprint Evaluation of cytotoxic, genotoxic and CYP450 enzymatic competition effects of Tanzanian plant extracts traditionally used for treatment of fungal infections
    Carolien J P van den Bout-van den Beukel
    Department of General Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Basic Clin Pharmacol Toxicol 102:515-26. 2008
    ..africana significantly induced CYP3A4 mRNA levels. These results indicate the possibility of potential medicinal plant-antiretroviral interactions...