Wanchun Tang

Summary

Publications

  1. doi request reprint Comparison of the durations of mild therapeutic hypothermia on outcome after cardiopulmonary resuscitation in the rat
    Sen Ye
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Dr, Rancho Mirage, CA 92270, USA
    Circulation 125:123-9. 2012
  2. ncbi request reprint One-shock versus three-shock defibrillation protocol significantly improves outcome in a porcine model of prolonged ventricular fibrillation cardiac arrest
    Wanchun Tang
    Weil Institute of Critical Care Medicine, 35 100 Bob Hope Dr, Rancho Mirage, California 92270, USA
    Circulation 113:2683-9. 2006
  3. ncbi request reprint Intravenous infusion of bone marrow mesenchymal stem cells improves myocardial function in a rat model of myocardial ischemia
    Tong Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 35:2587-93. 2007
  4. ncbi request reprint The effects of biphasic waveform design on post-resuscitation myocardial function
    Wanchun Tang
    Insitute of Critical Care Medicine, Palm Springs, California 92262 5309, USA
    J Am Coll Cardiol 43:1228-35. 2004
  5. doi request reprint Preserved cerebral microcirculation during cardiogenic shock
    Zhi Wan
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:2333-7. 2009
  6. ncbi request reprint Fixed-energy biphasic waveform defibrillation in a pediatric model of cardiac arrest and resuscitation
    Wanchun Tang
    The Institute of Critical Care Medicine, 1695 North Sunrise Way, Building 3, Palm Springs, CA 92262 5309, USA
    Crit Care Med 30:2736-41. 2002
  7. doi request reprint Individual effect of components of defibrillation waveform on the contractile function and intracellular calcium dynamics of cardiomyocytes
    Min Shan Tsai
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:2394-401. 2009
  8. pmc Clinical correlates of arterial lactate levels in STEMI patients
    Max Harry Weil
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, USA
    Crit Care 15:113. 2011
  9. doi request reprint Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation
    Shijie Sun
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:2282-6. 2010
  10. ncbi request reprint Levosimendan improves postresuscitation outcomes in a rat model of CPR
    Lei Huang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    J Lab Clin Med 146:256-61. 2005

Collaborators

Detail Information

Publications68

  1. doi request reprint Comparison of the durations of mild therapeutic hypothermia on outcome after cardiopulmonary resuscitation in the rat
    Sen Ye
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Dr, Rancho Mirage, CA 92270, USA
    Circulation 125:123-9. 2012
    ..The present study investigated whether a shorter duration of therapeutic hypothermia induced quickly and early after resuscitation would provide an equal improvement in the outcomes of cardiopulmonary resuscitation...
  2. ncbi request reprint One-shock versus three-shock defibrillation protocol significantly improves outcome in a porcine model of prolonged ventricular fibrillation cardiac arrest
    Wanchun Tang
    Weil Institute of Critical Care Medicine, 35 100 Bob Hope Dr, Rancho Mirage, California 92270, USA
    Circulation 113:2683-9. 2006
    ..The success of resuscitation with a 1-shock versus the conventional 3-shock defibrillation protocol was investigated subject to the range of treatment variation imposed by automated external defibrillators (AEDs)...
  3. ncbi request reprint Intravenous infusion of bone marrow mesenchymal stem cells improves myocardial function in a rat model of myocardial ischemia
    Tong Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 35:2587-93. 2007
    ..We investigated the effects of three different sites for delivery of bone marrow mesenchymal stem cells (MSCs) in a rat model of myocardial ischemia...
  4. ncbi request reprint The effects of biphasic waveform design on post-resuscitation myocardial function
    Wanchun Tang
    Insitute of Critical Care Medicine, Palm Springs, California 92262 5309, USA
    J Am Coll Cardiol 43:1228-35. 2004
    ..This study examined the effects of biphasic truncated exponential waveform design on survival and post-resuscitation myocardial function after prolonged ventricular fibrillation (VF)...
  5. doi request reprint Preserved cerebral microcirculation during cardiogenic shock
    Zhi Wan
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:2333-7. 2009
    ..Decreases in buccal microcirculatory flow are closely associated with the severity and outcomes of circulatory shock...
  6. ncbi request reprint Fixed-energy biphasic waveform defibrillation in a pediatric model of cardiac arrest and resuscitation
    Wanchun Tang
    The Institute of Critical Care Medicine, 1695 North Sunrise Way, Building 3, Palm Springs, CA 92262 5309, USA
    Crit Care Med 30:2736-41. 2002
    ..Accordingly, we investigated a method by which adult automated defibrillators may be adapted to deliver a 50-J ICBTE shock for pediatric defibrillation...
  7. doi request reprint Individual effect of components of defibrillation waveform on the contractile function and intracellular calcium dynamics of cardiomyocytes
    Min Shan Tsai
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:2394-401. 2009
    ..We hypothesized that peak current may play a more important role than energy in determining postshock dysfunction. Prolongation of the duration may reduce contractile impairment...
  8. pmc Clinical correlates of arterial lactate levels in STEMI patients
    Max Harry Weil
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, USA
    Crit Care 15:113. 2011
    ..That lactate value therefore identified high-risk patients as a complication, often with clinical signs of cardiogenic shock of corresponding severities...
  9. doi request reprint Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation
    Shijie Sun
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:2282-6. 2010
    ..To investigate whether hypothermia could be induced pharmacologically after resuscitation with the cannabinoid CB1/CB2 receptor agonist in a rat model and its effects on outcomes of cardiopulmonary resuscitation...
  10. ncbi request reprint Levosimendan improves postresuscitation outcomes in a rat model of CPR
    Lei Huang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    J Lab Clin Med 146:256-61. 2005
    ..Levosimendan and dobutamine both improved postresuscitation myocardial function. However, levosimendan produced more favorable postresuscitation myocardial function and increased the duration of postresuscitation survival...
  11. ncbi request reprint Intra-arrest rapid head cooling improves postresuscitation myocardial function in comparison with delayed postresuscitation surface cooling
    Min Shan Tsai
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:S434-9. 2008
    ..To compare resuscitation outcomes and myocardial function among intra-arrest head cooling, delayed surface cooling, and uncooled controls...
  12. doi request reprint Preserved heart rate variability during therapeutic hypothermia correlated to 96 hrs neurological outcomes and survival in a pig model of cardiac arrest
    Yongqin Li
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 40:580-6. 2012
    ..In the current study, we investigated the effect of rapid head cooling on 96-hr neurologic outcomes and survival by heart rate variability analysis in a pig model of prolonged cardiac arrest...
  13. ncbi request reprint Transthoracic application of electrical cardiopulmonary resuscitation for treatment of cardiac arrest
    Hao Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:S458-66. 2008
    ..This study examined electrical cardiopulmonary resuscitation for coronary perfusion pressures during ventricular fibrillation in a porcine model of cardiac arrest...
  14. ncbi request reprint Miniaturized mechanical chest compressor: a new option for cardiopulmonary resuscitation
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, United States
    Resuscitation 76:191-7. 2008
    ..We hypothesized that the 2 kg, low profile, portable device will be as effective as the standard pneumatic Thumper for restoring circulation during CPR...
  15. ncbi request reprint Levosimendan improves postresuscitation myocardial dysfunction after beta-adrenergic blockade
    Jinglan Wang
    Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, USA
    J Lab Clin Med 146:179-83. 2005
    ..When levosimendan was added, postresuscitation myocardial contractile function was improved even more...
  16. ncbi request reprint Evidence favoring the use of an alpha2-selective vasopressor agent for cardiopulmonary resuscitation
    Tommaso Pellis
    The Institute of Critical Care Medicine, Palm Springs, Calif 92262, USA
    Circulation 108:2716-21. 2003
    ..We further hypothesized that the resulting alpha2-actions of relatively brief duration would favor improved functions compared with the more prolonged effect of nonadrenergic vasopressin...
  17. ncbi request reprint The amplitude spectrum area correctly predicts improved resuscitation and facilitated defibrillation with head cooling
    Min Shan Tsai
    Well Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:S413-7. 2008
    ..We hypothesized that rapid head cooling initiated coincident with cardiopulmonary resuscitation improves amplitude spectrum area, and therefore is predictive of successful defibrillation...
  18. doi request reprint The effects of epinephrine on outcomes of normothermic and therapeutic hypothermic cardiopulmonary resuscitation
    Shijie Sun
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:2175-80. 2010
    ..To investigate the effects of epinephrine when administered during either normothermic or therapeutic hypothermic cardiopulmonary resuscitation on postresuscitation myocardial and cerebral function and survival...
  19. ncbi request reprint Exclusion of a patient assessment interval and extension of the CPR interval both mitigate post-resuscitation myocardial dysfunction in a swine model of cardiac arrest
    Yun Te Chang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270 1761, USA
    Resuscitation 76:285-90. 2008
    ..Interruptions of CPR may be reduced by eliminating repetition of shocks between periods of CPR, elimination of the interval for patient assessment before CPR, and extension of the periods of CPR...
  20. ncbi request reprint Microcirculation during cardiac arrest and resuscitation
    Michael Fries
    Weil Institute of Critical Care Medicine, Rancho Mirage, California, USA
    Crit Care Med 34:S454-7. 2006
    ..We evaluated serial changes and the effects of epinephrine on microcirculatory blood flow in the most severe form of circulatory failure, namely, cardiac arrest...
  21. ncbi request reprint A comparison between head cooling begun during cardiopulmonary resuscitation and surface cooling after resuscitation in a pig model of cardiac arrest
    Jun Guan
    Well Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:S428-33. 2008
    ....
  22. doi request reprint Survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest
    Tao Yu
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:916-21. 2010
    ..We hypothesized that nasopharyngeal cooling initiated during cardiopulmonary resuscitation would yield better resuscitation outcome when compared with cold saline infusion...
  23. ncbi request reprint Intravenous infusion of bone marrow mesenchymal stem cells improves brain function after resuscitation from cardiac arrest
    Tong Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:S486-91. 2008
    ..Coincidental evidence of improved brain function prompted the present study...
  24. ncbi request reprint Spontaneous gasping generates cardiac output during cardiac arrest
    Jing Xie
    Institute of Critical Care Medicine, Palm Springs, CA, USA
    Crit Care Med 32:238-40. 2004
    ..To measure stroke volumes coincident with spontaneous gasping during untreated ventricular fibrillation and to evaluate the effects of gasping...
  25. doi request reprint Delayed high-quality CPR does not improve outcomes
    Fengqing Song
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 82:S52-5. 2011
    ..Our objective was to compare outcomes following either immediate low-quality (LQ) CPR or delayed high-quality (HQ) CPR. We hypothesized that delayed HQ CPR will improve the outcomes of CPR in comparison to immediately performing LQ CPR...
  26. doi request reprint Intra-arrest selective brain cooling improves success of resuscitation in a porcine model of prolonged cardiac arrest
    Hao Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Resuscitation 81:617-21. 2010
    ..Our hypothesis was that rapid nasal cooling initiated during "low-flow" improves return of spontaneous resuscitation (ROSC)...
  27. doi request reprint Defibrillation delivered during the upstroke phase of manual chest compression improves shock success
    Yongqin Li
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:910-5. 2010
    ....
  28. doi request reprint A comparison of defibrillation efficacy between different impedance compensation techniques in high impedance porcine model
    Yongqin Li
    The Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 80:1312-7. 2009
    ..The first defibrillator (A) compensates high impedance by controlling current with fixed shock duration, while the second defibrillator (B) by prolonging the shock duration...
  29. ncbi request reprint Microvascular blood flow during cardiopulmonary resuscitation is predictive of outcome
    Michael Fries
    The Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, United States
    Resuscitation 71:248-53. 2006
    ..82, p<0.01). Microvascular blood flow in the sublingual mucosa is therefore closely related to coronary perfusion pressure during cardiopulmonary resuscitation and both are predictive of outcome...
  30. doi request reprint The optimal phasic relationship between synchronized shock and mechanical chest compressions
    Yongqin Li
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Resuscitation 81:724-9. 2010
    ..We therefore undertook a study to assess the effects of timing of defibrillation in the mechanical chest compression cycle on the defibrillation threshold (DFT) using a porcine model of cardiac arrest...
  31. doi request reprint Minimal interruption of cardiopulmonary resuscitation for a single shock as mandated by automated external defibrillations does not compromise outcomes in a porcine model of cardiac arrest and resuscitation
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:3048-53. 2008
    ..We hypothesized that an 8-sec interruption of chest compressions for a single shock, as mandated by automated external defibrillations, would not impair initial resuscitation and outcomes of cardiopulmonary resuscitation...
  32. ncbi request reprint The quality of chest compressions during cardiopulmonary resuscitation overrides importance of timing of defibrillation
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Dr, Rancho Mirage, CA 92270, USA
    Chest 132:70-5. 2007
    ..We address the quality of chest compressions and the impact on initial defibrillation or initial chest compressions after sudden death...
  33. ncbi request reprint Stroke volumes generated by precordial compression during cardiac resuscitation
    Kada Klouche
    Institute of Critical Care Medicine, Palm Springs, CA, USA
    Crit Care Med 30:2626-31. 2002
    ..To quantitate stroke volumes generated by precordial compression during cardiopulmonary resuscitation and to determine their relationship to coronary perfusion pressure and the success of resuscitation...
  34. ncbi request reprint Evolution of the stone heart after prolonged cardiac arrest
    Kada Klouche
    Institute of Critical Care Medicine, Palm Springs, CA, USA
    Chest 122:1006-11. 2002
    ..We therefore measured sequential changes in left ventricular (LV) volumes and free-wall thickness of the heart during CPR in an experimental model...
  35. doi request reprint Epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:1408-15. 2009
    ..On the basis of coincidental observations on changes in microvascular flow in the cerebral cortex, we hypothesized that epinephrine selectively decreases microvascular flow...
  36. doi request reprint Comparison of efficacy of pulsed biphasic waveform and rectilinear biphasic waveform in a short ventricular fibrillation pig model
    Yongqin Li
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, United States
    Resuscitation 80:1047-51. 2009
    ..In this study, we compared pulsed biphasic waveform (PBW) with rectilinear biphasic waveform (RBW) and their effects on terminating ventricular fibrillation (VF)...
  37. ncbi request reprint A comparison of alpha-methylnorepinephrine, vasopressin and epinephrine for cardiac resuscitation
    Kada Klouche
    The Institute of Critical Care Medicine, 1695 North Sunrise Way, Bldg 3, 92262 5309, Palm Springs, CA, USA
    Resuscitation 57:93-100. 2003
    ..Both post-resuscitation myocardial function and survival were most improved after administration of the selective alpha(2)-adrenergic agonist, intermediate after vasopressin and least after epinephrine and saline placebo...
  38. ncbi request reprint Mechanism by which activation of delta-opioid receptor reduces the severity of postresuscitation myocardial dysfunction
    Xiangshao Fang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 34:2607-12. 2006
    ..In the present study, we investigated the potential mechanism of myocardial protection following delta-opioid receptor activation in a rat model of cardiac arrest and cardiopulmonary resuscitation...
  39. ncbi request reprint Effects of epinephrine and vasopressin on cerebral microcirculatory flows during and after cardiopulmonary resuscitation
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 35:2145-9. 2007
    ..Accordingly, we compared the effects of nonadrenergic vasopressin with those of epinephrine on cerebral cortical microvascular flow together with cortical tissue Po2 and Pco2 as indicators of cortical tissue ischemia...
  40. doi request reprint Cerebral cortical microvascular flow during and following cardiopulmonary resuscitation after short duration of cardiac arrest
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 77:229-34. 2008
    ..To examine changes in cerebral cortical macro- and microcirculation and their relationship to the severity of brain ischaemia during and following resuscitation from a short duration of cardiac arrest...
  41. doi request reprint The cerebral microcirculation is protected during experimental hemorrhagic shock
    Zhi Wan
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:928-32. 2010
    ..We propose to relate changes in the macrocirculation to the buccal and cerebral microcirculations during hemorrhage and after fluid resuscitation...
  42. doi request reprint Opioid receptor agonist reduces myocardial ischemic injury when administered during early phase of myocardial ischemia
    Yi Shan
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 81:761-5. 2010
    ..We proposed to investigate the separate effects of ischemia and reperfusion injury on postresuscitation myocardial dysfunction...
  43. ncbi request reprint Comparison of rectilinear biphasic waveform with biphasic truncated exponential waveform in a pediatric defibrillation model
    Jinglan Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 35:1961-5. 2007
    ..To compare the rectilinear biphasic waveform with a biphasic truncated exponential waveform for pediatric defibrillation...
  44. ncbi request reprint A comparison of electrically induced cardiac arrest with cardiac arrest produced by coronary occlusion
    Jinglan Wang
    The Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, United States
    Resuscitation 72:477-83. 2007
    ..Accordingly, a potentially more clinically relevant model was investigated in which spontaneous VF followed acute myocardial ischemia...
  45. doi request reprint The effects of a newly developed miniaturized mechanical chest compressor on outcomes of cardiopulmonary resuscitation in a porcine model*
    Wei Chen
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 40:3007-12. 2012
    ..We investigated the effects of a newly developed miniaturized chest compressor on the outcomes of cardiopulmonary resuscitation...
  46. doi request reprint Optimizing the duration of CPR prior to defibrillation improves the outcome of CPR in a rat model of prolonged cardiac arrest
    Shijie Sun
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 82:S3-7. 2011
    ..This study was to investigate whether optimal duration of CPR prior to defibrillation could be guided by Amplitude Spectrum Analysis (AMSA) in the setting of prolonged VF on outcome of CPR...
  47. ncbi request reprint Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction
    Lei Huang
    Institute of Critical Care Medicine, Palm Springs, CA, USA
    Crit Care Med 33:487-91. 2005
    ....
  48. doi request reprint Hypothermia improves ventricular myocyte contractility under conditions of normal perfusion and after an interval of ischemia
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 81:898-903. 2010
    ..The effects of hypothermia on myocyte contractility were investigated under conditions of normal perfusion and after a 10min interval of ischemia...
  49. doi request reprint Apoptosis is not involved in the mechanism of myocardial dysfunction after resuscitation in a rat model of cardiac arrest and cardiopulmonary resuscitation
    Fengqing Song
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 38:1329-34. 2010
    ....
  50. ncbi request reprint Effects of biphasic waveforms on outcomes of cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest
    Yun Te Chang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 34:3024-8. 2006
    ..Defibrillation via sequential pulses and encircling, overlapping multiple pathway may depolarize a larger myocardial mass and facilitate transthoracic defibrillation...
  51. ncbi request reprint Postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation
    Tingyan Xu
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:188-92. 2008
    ..We therefore investigated the postresuscitation left ventricular diastolic function following prolonged cardiac arrest and subsequent cardiopulmonary resuscitation...
  52. doi request reprint Buccal capnometry for quantitating the severity of hemorrhagic shock
    Gianluca A A M Cammarata
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Shock 31:207-11. 2009
    ..This measurement is therefore likely to serve as a useful guide for the immediate management of hemorrhagic shock...
  53. ncbi request reprint Adverse outcomes of interrupted precordial compression during automated defibrillation
    Ting Yu
    Institute of Critical Care Medicine, Palm Springs, Calif 92262 5309, USA
    Circulation 106:368-72. 2002
    ..The present study was undertaken to evaluate the effects of these interruptions during the operation of AEDs...
  54. ncbi request reprint The characteristics of postcountershock pulseless electrical activity may indicate the outcome of CPR
    Xiangshao Fang
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA, USA
    Resuscitation 69:303-9. 2006
    ..We therefore investigated outcomes after postcountershock PEA, and aimed to develop a scoring system for outcome classification at the onset of initial postcountershock PEA...
  55. doi request reprint Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model
    Yinlun Weng
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA
    Resuscitation 83:1145-51. 2012
    ..The present study was to explore the potential mechanisms of WIN55, 212-2 on thermoregulation following resuscitation and to investigate which class of CB receptors was involved in WIN55, 212-2-induced hypothermia...
  56. ncbi request reprint Increases in tissue Pco2 during circulatory shock reflect selective decreases in capillary blood flow
    Michael Fries
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 34:446-52. 2006
    ..This study addresses simultaneous changes in gastric and buccal tissue Pco2 with changes in microcirculatory blood flow in a rat model of circulatory shock induced by cecal ligation and puncture...
  57. ncbi request reprint Carvedilol mitigates adverse effects of epinephrine during cardiopulmonary resuscitation
    Lei Huang
    The Institute of Critical Care Medicine, Palm Springs, CA, USA
    J Cardiovasc Pharmacol Ther 10:113-20. 2005
    ..Because carvedilol is both a nonselective beta- and alpha1-selective adrenergic receptor-blocking agent, we hypothesized that pretreatment with carvedilol would convert the actions of epinephrine to that of a selective alpha2-agonist...
  58. ncbi request reprint Cardiopulmonary resuscitation in a rat model of chronic myocardial ischemia
    Xiangshao Fang
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Dr, Rancho Mirage, CA 92270, USA
    J Appl Physiol 101:1091-6. 2006
    ..This model would suggest further clinically relevant investigation on cardiac arrest and CPR...
  59. ncbi request reprint Increases in both buccal and sublingual partial pressure of carbon dioxide reflect decreases of tissue blood flows in a porcine model during hemorrhagic shock
    Tommaso Pellis
    Institute of Critical Care Medicine, Rancho Mirage, California, USA
    J Trauma 58:817-24. 2005
    ..Because hypercarbia is a general phenomenon of perfusion failure, this study investigated whether sublingual and buccal mucosal tissue PCO2 also serve as a sensitive indicator of systemic blood flow during hemorrhagic shock...
  60. ncbi request reprint Comparison of buccal microcirculation between septic and hemorrhagic shock
    Xiangshao Fang
    Weil Institute of Critical Care Medicine, Rancho Mirage, California, USA
    Crit Care Med 34:S447-53. 2006
    ..In this study, we investigated the effect of the same level of mean arterial pressure (MAP) or cardiac index on the changes in buccal microcirculation between septic and hemorrhagic shock...
  61. ncbi request reprint Outcomes of CPR in the presence of partial occlusion of left anterior descending coronary artery
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, United States
    Resuscitation 75:357-65. 2007
    ....
  62. ncbi request reprint Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation
    Yongqin Li
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:211-5. 2008
    ..We therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram...
  63. doi request reprint Free radicals mediate postshock contractile impairment in cardiomyocytes
    Min Shan Tsai
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 36:3213-9. 2008
    ....
  64. doi request reprint Mesenchymal stem cells improve outcomes of cardiopulmonary resuscitation in myocardial infarcted rats
    Tong Wang
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, USA
    J Mol Cell Cardiol 46:378-84. 2009
    ....
  65. doi request reprint Coronary blood flow produced by muscle contractions induced by intracardiac electrical CPR during ventricular fibrillation
    Hao Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, California, USA
    Pacing Clin Electrophysiol 32:S223-7. 2009
    ..It has been reported that transthoracic electrical cardiopulmonary resuscitation (ECPR) generates coronary perfusion pressures (CPP) similar to manual chest compressions (MCC). We hypothesized that intracardiac ECPR produces similar CPP...
  66. doi request reprint Cardiopulmonary resuscitation: from the beginning to the present day
    Giuseppe Ristagno
    Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, USA
    Crit Care Clin 25:133-51, ix. 2009
    ..This article summarizes the major events that encompass the history of cardiopulmonary resuscitation, beginning with ancient history and evolving into the current American Heart Association's commitment to save hearts...
  67. doi request reprint The potential mechanisms of reduced incidence of ventricular fibrillation as the presenting rhythm in sudden cardiac arrest
    Hao Wang
    Weil Institute of Critical Care Medicine, Rancho Mirage, CA, USA
    Crit Care Med 37:26-31. 2009
    ....
  68. ncbi request reprint Myocardial performance index following electrically induced or ischemically induced cardiac arrest
    Tingyan Xu
    The Weil Institute of Critical Care Medicine, 35100 Bob Hope Drive, Rancho Mirage, CA 92270, United States
    Resuscitation 76:103-7. 2008
    ..We sought to investigate the echocardiographic myocardial performance index (MPI) to assess post-resuscitation myocardial function following electrically and ischemically induced ventricular fibrillation (VF)...