Murtaza Tambuwala

Summary

Affiliation: UCD
Location: Dublin, Ireland
URL: www.murtazatambuwala.tk

Publications

  1. pmc PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells
    Kathleen A O'Hagan
    Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    Proc Natl Acad Sci U S A 106:2188-93. 2009
  2. doi request reprint Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function
    Murtaza M Tambuwala
    The Conway Institute, University College Dublin, Ireland
    Gastroenterology 139:2093-101. 2010
  3. doi request reprint An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia
    Susan F Fitzpatrick
    UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    J Immunol 186:1091-6. 2011

Collaborators

Detail Information

Publications4

  1. pmc PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells
    Kathleen A O'Hagan
    Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    Proc Natl Acad Sci U S A 106:2188-93. 2009
    ....
  2. doi request reprint Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function
    Murtaza M Tambuwala
    The Conway Institute, University College Dublin, Ireland
    Gastroenterology 139:2093-101. 2010
    ..Hypoxia inducible factor (HIF) prolyl hydroxylase inhibitors are protective in mouse models of inflammatory bowel disease (IBD). Here, we investigated the therapeutic target(s) and mechanism(s) involved...
  3. doi request reprint An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia
    Susan F Fitzpatrick
    UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    J Immunol 186:1091-6. 2011
    ..These results implicate an essential role for NF-κB signaling in inflammatory gene expression in response to hypoxia both through the regulation of HIF-1 and through direct effects upon target gene expression...