Jui I Chao

Summary

Affiliation: Tzu Chi University
Country: Taiwan

Publications

  1. ncbi Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells
    Jui I Chao
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701 Section 3 Chung Yang Road, Hualien 970, Taiwan
    J Biol Chem 279:20267-76. 2004
  2. ncbi Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT
    Jui I Chao
    Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien 970, Taiwan
    Mol Cancer Ther 6:3039-48. 2007
  3. ncbi The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells
    Jui I Chao
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Mol Pharmacol 69:154-64. 2006
  4. ncbi Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway
    Jui I Chao
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, Hualien, Taiwan
    Toxicol Sci 90:73-86. 2006
  5. ncbi Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells
    Pao Chen Kuo
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, No 7 Section 3 Chung Yang Road, Hualien 970, Taiwan
    J Biol Chem 279:55875-85. 2004
  6. ncbi Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells
    Po Wen Hsiao
    Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Toxicol Appl Pharmacol 222:97-104. 2007
  7. doi 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway
    Tzu Sheng Hsu
    Institute of Pharmacology and Toxicology, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Cancer Chemother Pharmacol 62:799-808. 2008
  8. doi Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells
    Shu Jun Chiu
    Department of Life Science, Tzu Chi University, Hualien 970, Taiwan
    Toxicol Lett 179:63-70. 2008
  9. ncbi Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells
    Shih Hsin Hsu
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701 Section 3, Hualien 970, Taiwan
    Toxicol Lett 159:47-59. 2005
  10. ncbi Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells
    Shu Jun Chiu
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Toxicol Lett 167:122-30. 2006

Collaborators

  • Shu Jun Chiu
  • Tsui Chun Tsou
  • Chih Chien Tsai
  • Yi Jang Lee
  • Kuang Kai Liu
  • Huei Fang Liu
  • Po Wen Hsiao
  • Ren Huei Jiang
  • Chia Liang Cheng
  • Tzu Sheng Hsu
  • Chia Ching Chang
  • Ted H Chiu
  • Shih Hsin Hsu
  • Johnson Lin
  • Pao Chen Kuo
  • Wen Chi Su
  • Hou Syun Huang
  • Chi Ching Wang
  • Yen Peng Ho
  • Po Yi Chen
  • Chinpiao Chen
  • Mei Fang Chen
  • Pei Ting Lee
  • Tony J F Lee

Detail Information

Publications16

  1. ncbi Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells
    Jui I Chao
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701 Section 3 Chung Yang Road, Hualien 970, Taiwan
    J Biol Chem 279:20267-76. 2004
    ..Our results indicated for the first time that NO inhibited the expression of survivin, which was down-regulated by the p38 MAP kinase pathway...
  2. ncbi Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT
    Jui I Chao
    Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien 970, Taiwan
    Mol Cancer Ther 6:3039-48. 2007
    ....
  3. ncbi The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells
    Jui I Chao
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Mol Pharmacol 69:154-64. 2006
    ..As a whole, our results indicate that the inhibition of survivin and securin protein expression may increase the cell death and growth inhibition after cytochalasin B treatment in human cancer cells...
  4. ncbi Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway
    Jui I Chao
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, Hualien, Taiwan
    Toxicol Sci 90:73-86. 2006
    ..Together, it is the first time to demonstrate that the inhibition of securin expression induced by arsenite increases the chromosomal instability and apoptosis via a p53-independent pathway...
  5. ncbi Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells
    Pao Chen Kuo
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, No 7 Section 3 Chung Yang Road, Hualien 970, Taiwan
    J Biol Chem 279:55875-85. 2004
    ..Together, our results suggest that survivin can reduce the cell growth inhibition and apoptosis, and p53 elevates the p21 level, which may attenuate the cell death in the quercetin-treated human lung carcinoma cells...
  6. ncbi Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells
    Po Wen Hsiao
    Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Toxicol Appl Pharmacol 222:97-104. 2007
    ....
  7. doi 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway
    Tzu Sheng Hsu
    Institute of Pharmacology and Toxicology, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Cancer Chemother Pharmacol 62:799-808. 2008
    ..A new synthetic compound 7-chloro-6-piperidin-1-yl-quinoline-5,8-dione (designed as PT-262) derived from 6,7-dichloroquinoline-5,8-dione on its anticancer activity was investigated in this study...
  8. doi Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells
    Shu Jun Chiu
    Department of Life Science, Tzu Chi University, Hualien 970, Taiwan
    Toxicol Lett 179:63-70. 2008
    ..Our findings suggest that p38 MAPK may oppositely regulate securin protein expression and gamma-H2AX formation in the oxaliplatin-induced apoptosis of human colorectal cancer cells...
  9. ncbi Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells
    Shih Hsin Hsu
    Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701 Section 3, Hualien 970, Taiwan
    Toxicol Lett 159:47-59. 2005
    ..Together, our results indicate that arsenite can inhibit the alpha7-nAChR protein expression and cause the cell injury in the vascular endothelial cells...
  10. ncbi Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells
    Shu Jun Chiu
    Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 970, Taiwan
    Toxicol Lett 167:122-30. 2006
    ..As a whole, it is the first time to demonstrate that oxaliplatin inhibits the securin protein expression via a p53-dependent pathway, and p53 and securin may modulate the oxaliplatin-induced cytotoxicity in human colorectal cancer cells...
  11. doi Opposite expression of securin and γ-H2AX regulates baicalein-induced cancer cell death
    Ren Huei Jiang
    Molecular Anticancer Laboratory, Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30068, Taiwan
    J Cell Biochem 111:274-83. 2010
    ..Taken together, our findings suggest that the opposing effects of baicalein on securin and γ-H2AX levels may be involved in the regulation of cell viability and genomic stability by this compound...
  12. ncbi Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation
    Shu Jun Chiu
    Department of Life Science, College of Life Sciences, Tzu Chi University, Hualien 970, Taiwan
    Chem Biol Interact 170:153-61. 2007
    ..As a whole, these findings suggest that the existence of securin promotes apoptosis via a p53-indpendent pathway after radiation in human colorectal cancer cells...
  13. pmc Nanometer-sized diamond particle as a probe for biolabeling
    Jui I Chao
    Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien, 970 Taiwan
    Biophys J 93:2199-208. 2007
    ..The easily detected natural fluorescent and Raman intrinsic signals, penetration ability, and low cytotoxicity of cNDs render them promising agents in multiple medical applications...
  14. doi Endocytic carboxylated nanodiamond for the labeling and tracking of cell division and differentiation in cancer and stem cells
    Kuang Kai Liu
    Molecular Anticancer Laboratory, Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30068, Taiwan
    Biomaterials 30:4249-59. 2009
    ..Together, these findings provide that endocytic ND particles are non-cytotoxic in cell division and differentiation, which can be applied for the labeling and tracking of cancer and stem cells...
  15. ncbi Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond
    Kuang Kai Liu
    Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien 970, Taiwan Biomedical Nanotechnology Laboratory, Tzu Chi University, Hualien 970, Taiwan Department of Biological Science and Technology, National Chiao Tung University, Hsin Chu 300, Taiwan
    Nanotechnology 19:205102. 2008
    ..These results indicate that cND-conjugated α-BTX still preserves its biological activity in blocking the function of α7-nAChR, and provide a visual system showing the binding of α-BTX to α7-nAChR...
  16. ncbi Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells
    Johnson Lin
    Hemato Oncology Section, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    Biochem Pharmacol 70:658-67. 2005
    ..Together, this is the first report that combination of COX-2 inhibitors and oxaliplatin can increase the reduction of survivin protein expression, growth inhibition, and death in human colon cancer cells...