Chien Han Lai

Summary

Affiliation: Tri-Service General Hospital
Country: Taiwan

Publications

  1. doi request reprint Frontal-insula gray matter deficits in first-episode medication-naïve patients with major depressive disorder
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, ROC Electronic address
    J Affect Disord 160:74-9. 2014
  2. doi request reprint Changes in regional homogeneity of parieto-temporal regions in panic disorder patients who achieved remission with antidepressant treatment
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, ROC Electronic address
    J Affect Disord 151:709-14. 2013
  3. doi request reprint Improvements in white matter micro-structural integrity of right uncinate fasciculus and left fronto-occipital fasciculus of remitted first-episode medication-naïve panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, No 45, Cheng Hsin St, Pai Tou Destrict, Taipei City, Taiwan, ROC
    J Affect Disord 150:330-6. 2013
  4. doi request reprint Fronto-occipital fasciculus, corpus callosum and superior longitudinal fasciculus tract alterations of first-episode, medication-naïve and late-onset panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    J Affect Disord 146:378-82. 2013
  5. doi request reprint Gray matter volume in major depressive disorder: a meta-analysis of voxel-based morphometry studies
    Chien Han Lai
    Division of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    Psychiatry Res 211:37-46. 2013
  6. doi request reprint Changes in gray matter volume of remitted first-episode, drug-naïve, panic disorder patients after 6-week antidepressant therapy
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    J Psychiatr Res 47:122-7. 2013
  7. doi request reprint Fronto-temporo-insula gray matter alterations of first-episode, drug-naïve and very late-onset panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Affect Disord 140:285-91. 2012
  8. doi request reprint Frontal regional homogeneity increased and temporal regional homogeneity decreased after remission of first-episode drug-naïve major depressive disorder with panic disorder patients under duloxetine therapy for 6 weeks
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Affect Disord 136:453-8. 2012
  9. doi request reprint First episode drug-naïve major depressive disorder with panic disorder: gray matter deficits in limbic and default network structures
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    Eur Neuropsychopharmacol 20:676-82. 2010
  10. doi request reprint Major depressive disorder: gender differences in symptoms, life quality, and sexual function
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Xindian City, Taipei County, Taiwan
    J Clin Psychopharmacol 31:39-44. 2011

Detail Information

Publications15

  1. doi request reprint Frontal-insula gray matter deficits in first-episode medication-naïve patients with major depressive disorder
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, ROC Electronic address
    J Affect Disord 160:74-9. 2014
    ..This study is designed to investigate the gray matter volume (GMV) deficits in patients with first-episode medication-naïve major depressive disorder (MDD)...
  2. doi request reprint Changes in regional homogeneity of parieto-temporal regions in panic disorder patients who achieved remission with antidepressant treatment
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, ROC Electronic address
    J Affect Disord 151:709-14. 2013
    ..This study was aimed to study the treatment effects of antidepressant for regional homogeneity (ReHo), an indicator of synchronization of brain function, in panic disorder (PD) patients...
  3. doi request reprint Improvements in white matter micro-structural integrity of right uncinate fasciculus and left fronto-occipital fasciculus of remitted first-episode medication-naïve panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, No 45, Cheng Hsin St, Pai Tou Destrict, Taipei City, Taiwan, ROC
    J Affect Disord 150:330-6. 2013
    ..We designed this study to investigate neural correlates of white matter micro-structural integrity of remitted patients with first-episode, medication-naïve and very late-onset panic disorder...
  4. doi request reprint Fronto-occipital fasciculus, corpus callosum and superior longitudinal fasciculus tract alterations of first-episode, medication-naïve and late-onset panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    J Affect Disord 146:378-82. 2013
    ..Because of limited knowledge about white matter (WM) tract in panic disorder, we designed this study to investigate alterations of WM tracts in first-episode medication-naïve panic disorder patients...
  5. doi request reprint Gray matter volume in major depressive disorder: a meta-analysis of voxel-based morphometry studies
    Chien Han Lai
    Division of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    Psychiatry Res 211:37-46. 2013
    ..The potential confounding factors had little impact on the results. This meta-analysis suggested GM deficits of the anterior cingulate cortex might be important in the etiology of MDD...
  6. doi request reprint Changes in gray matter volume of remitted first-episode, drug-naïve, panic disorder patients after 6-week antidepressant therapy
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    J Psychiatr Res 47:122-7. 2013
    ..We also determined any persistent GMV deficits after remission to assess for "state-dependent brain changes" and "trait-like brain changes" for PD...
  7. doi request reprint Fronto-temporo-insula gray matter alterations of first-episode, drug-naïve and very late-onset panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Affect Disord 140:285-91. 2012
    ..Besides, differences of onset age might represent different clinical subgroups. Therefore we designed this study to investigate gray matter deficits in this subgroup of patients...
  8. doi request reprint Frontal regional homogeneity increased and temporal regional homogeneity decreased after remission of first-episode drug-naïve major depressive disorder with panic disorder patients under duloxetine therapy for 6 weeks
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Affect Disord 136:453-8. 2012
    ..We designed this study to investigate the changes of regional homogeneity (ReHo) after a 6-week duloxetine therapy in first-episode drug-naïve major depressive disorder with panic disorder (FEMDDPD) patients...
  9. doi request reprint First episode drug-naïve major depressive disorder with panic disorder: gray matter deficits in limbic and default network structures
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    Eur Neuropsychopharmacol 20:676-82. 2010
    ..The decline of gray matter volumes might have started since the first episode...
  10. doi request reprint Major depressive disorder: gender differences in symptoms, life quality, and sexual function
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Xindian City, Taipei County, Taiwan
    J Clin Psychopharmacol 31:39-44. 2011
    ..To investigate the gender differences of symptoms, life quality, functional impairment, and sexual function of patients with moderately severe major depressive disorder (MDD)...
  11. doi request reprint A subtle grey-matter increase in first-episode, drug-naive major depressive disorder with panic disorder after 6 weeks' duloxetine therapy
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    Int J Neuropsychopharmacol 14:225-35. 2011
    ..These improvements might be related to a modest increase of grey matter in state marker regions of the brain. The deficits of trait marker regions were more evident and are likely to be important for pathogenesis...
  12. doi request reprint Duloxetine's modest short-term influences in subcortical structures of first episode drug-naïve patients with major depressive disorder and panic disorder
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    Psychiatry Res 194:157-62. 2011
    ..The volumetric increases were correlated with responses of clinical symptoms. The results suggested that duloxetine possibly contributed to modest increases in several subcortical areas of these patients with remission...
  13. doi request reprint Patterns of fractional amplitude of low-frequency oscillations in occipito-striato-thalamic regions of first-episode drug-naïve panic disorder
    Chien Han Lai
    Division of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
    J Affect Disord 142:180-5. 2012
    ....
  14. doi request reprint Decreased regional homogeneity in lingual gyrus, increased regional homogeneity in cuneus and correlations with panic symptom severity of first-episode, medication-naïve and late-onset panic disorder patients
    Chien Han Lai
    Department of Psychiatry, Cheng Hsin General Hospital, No 45, Cheng Hsin Street, Pai Tou District, Taipei City, Taiwan, ROC
    Psychiatry Res 211:127-31. 2013
    ..ReHo differences found in the left lingual gyrus and the right cuneus might suggest sensory and inhibitory dysfunction in first-episode, medication-naïve, late-onset patients with PD...
  15. doi request reprint Gray matter deficits in panic disorder: a pilot study of meta-analysis
    Chien Han Lai
    Department of Psychiatry, Buddhist Tzu Chi General Hospital, Taipei Branch, National Yang Ming University, Taipei, Taiwan
    J Clin Psychopharmacol 31:287-93. 2011
    ..This study aimed to conduct a meta-analysis of published voxel-based morphometry studies in panic disorder (PD)...