Hsiou Yu Ding
Affiliation: Tri-Service General Hospital
Chiang C, Ding H, Tsai Y, Chang T. Production of Two Novel Methoxy-Isoflavones from Biotransformation of 8-Hydroxydaidzein by Recombinant Escherichia coli Expressing O-Methyltransferase SpOMT2884 from Streptomyces peucetius. Int J Mol Sci. 2015;16:27816-23 pubmed publisher
..5% of the control at 25 Î¼M. This is the first report on the 8-O-methylation activity of OMT toward isoflavones. In addition, the present study also first identified compound (1) with potent melanogenesis inhibitory activity. ..
Wang S, Liang C, Liang F, Ding H, Lin S, Huang G, et al
. The Inhibitory Mechanisms Study of 5,6,4'-Trihydroxy-7,3'-Dimethoxyflavone against the LPS-Induced Macrophage Inflammatory Responses through the Antioxidant Ability. Molecules. 2016;21:136 pubmed publisher
..These results identify 5-TDMF as an anti-oxidant and anti-inflammatory compound, explain the pharmacologic function of Anisomeles ovata and suggest its great potential as a new anti-inflammatory remedy. ..
Ding H, Wu P, Wu M. Cleome rutidosperma and Euphorbia thymifolia Suppress Inflammatory Response via Upregulation of Phase II Enzymes and Modulation of NF-?B and JNK Activation in LPS-Stimulated BV2 Microglia. Int J Mol Sci. 2016;17: pubmed publisher
..They may offer therapeutic potential for suppressing overactivated microglia and alleviating neurodegeneration. ..
Lin R, Yen C, Chou T, Chiang F, Wang G, Tseng Y, et al
. Antioxidant, anti-adipocyte differentiation, antitumor activity and anthelmintic activities against Anisakis simplex and Hymenolepis nana of yakuchinone A from Alpinia oxyphylla. BMC Complement Altern Med. 2013;13:237 pubmed publisher
..Alpinia oxyphylla is a common remedy in traditional Chinese medicine. Yakuchinone A is a major constituent of A. oxyphylla and exhibits anti-inflammatory, antitumor, antibacterial, and gastric protective activities...