Research Topics
| Te Sheng ChangSummaryAffiliation: Tri-Service General Hospital Country: Taiwan Publications
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Detail Information
Publications
Identifying 6,7,4'-trihydroxyisoflavone as a potent tyrosinase inhibitorTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, Taiwan
Biosci Biotechnol Biochem 69:1999-2001. 2005..The results suggest that hydroxyl groups at the C-6 and C-7 positions of the isoflavone skeleton might play an important role in the expression of tyrosinase inhibitory activity...
Two potent suicide substrates of mushroom tyrosinase: 7,8,4'-trihydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavoneTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, 33 sec 2 Shu Lin Street, Tainan, Taiwan
J Agric Food Chem 55:2010-5. 2007..The present study demonstrated that 7,8,4'-trihydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavone are potent suicide substrates of mushroom tyrosinase...
An updated review of tyrosinase inhibitorsTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, 33 sec 2 Shu Lin St, Tainan, Taiwan E Mail Tel 886 6 2606283
Int J Mol Sci 10:2440-75. 2009..This article surveys tyrosinase inhibitors newly discovered from natural and synthetic sources. The inhibitory strength is compared with that of a standard inhibitor, kojic acid, and their inhibitory mechanisms are discussed...
Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activityHsiou Yu Ding
Institute of Cosmetics Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan, R O C
Exp Dermatol 20:720-4. 2011..A 2% gel preparation of 2,5-DHAP applied to the skin of mice significantly increased the average skin-whitening index (L value), indicating its potential use as a treatment for skin hyperpigmentation in humans...
Metabolism of the soy isoflavones daidzein and genistein by fungi used in the preparation of various fermented soybean foodsTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, Tainan, Taiwan
Biosci Biotechnol Biochem 71:1330-3. 2007..The metabolites of daidzein and genistein by Aspergillus strains were identified as 8-hydroxydaidzein and 8-hydroxygenistein, respectively, based on their mass, (1)H-, and (13)C-NMR spectra...
Inhibitory effect of a water extract from Pemphis acidula on melanogenesis in mouse B16 melanoma cellsHsiou Yu Ding
Institute of Cosmetics Science, Chia Nan University of Pharmacy and Science, National University of Tainan, Taiwan, ROC
J Cosmet Sci 62:41-8. 2011..From the present study, PAE is proven to be a good candidate as a skin-whitening agent for treatment of skin hyperpigmentation...
Inhibitory effect of homochlorcyclizine on melanogenesis in α-melanocyte stimulating hormone-stimulated mouse B16 melanoma cellsTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, Tainan, Taiwan
Arch Pharm Res 35:119-27. 2012....
Isolation and characterization of Streptomyces hiroshimensis strain TI-C3 with anti-tyrosinase activityTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, 33 sec 2, Shu Lin St, Tainan, Taiwan
J Cosmet Sci 59:33-40. 2008..The anti-tyrosinase activity of the strain was improved to 905 U/ml under cultivation, using glucose and malt extract as the sole carbon and nitrogen sources, respectively...
Identifying 8-hydroxynaringenin as a suicide substrate of mushroom tyrosinaseTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, Tainan, Taiwan
J Cosmet Sci 61:205-10. 2010....
Inhibitory effect of danazol on melanogenesis in mouse B16 melanoma cellsTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, Tainan 700, Taiwan
Arch Pharm Res 33:1959-65. 2010..These results indicate that danazol inhibits melanogenesis in B16 cells via reducing the tyrosinase activity by post-transcriptional regulation...
8-Hydroxydaidzein is unstable in alkaline solutionsTe Sheng Chang
Department of Biological Science and Technology, National University of Tainan, 33 sec 2, Shu Lin St, Tainan, Taiwan
J Cosmet Sci 60:353-7. 2009..All the results demonstrated that 8-hydroxydaidzein is unstable in alkaline solutions. According to the data in the present report, it is recommended that 8-hydroxydaidzein be formulated in an acid solution for its applications...
