Jaw Ching Wu

Summary

Affiliation: Taipei Veterans General Hospital
Country: Taiwan

Publications

  1. pmc Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC
    Hsei Wei Wang
    Institute of Clinical Medicine, National Yang Ming University, NO, 201, Sec, 2, Shih Pai Rd, Taipei, Taiwan
    BMC Genomics 14:736. 2013
  2. ncbi request reprint Characterization and phylogenetic analysis of a novel hepatitis D virus strain discovered by restriction fragment length polymorphism analysis
    J C Wu
    Department of Medicine, Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    J Gen Virol 79:1105-13. 1998
  3. ncbi request reprint "Defective" mutations of hepatitis D viruses in chronic hepatitis D patients
    Jaw Ching Wu
    Institute of Clinical Medicine, National Yang Ming University, Taipei 112, Taiwan, China
    World J Gastroenterol 11:1658-62. 2005
  4. ncbi request reprint Functional and clinical significance of hepatitis D virus genotype II infection
    J C Wu
    Department of Medical Research and Education, Institute of Clinical Medicine, Taipei Veterans General Hospital, National Yang Ming University, Taiwan
    Curr Top Microbiol Immunol 307:173-86. 2006
  5. ncbi request reprint Spread of hepatitis E virus among different-aged pigs: two-year survey in Taiwan
    Jaw Ching Wu
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Med Virol 66:488-92. 2002
  6. ncbi request reprint Clinical and epidemiological implications of swine hepatitis E virus infection
    J C Wu
    Institute of Clinical Medicine and Division of Gastroenterology, Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Med Virol 60:166-71. 2000
  7. ncbi request reprint Recombination of hepatitis D virus RNA sequences and its implications
    J C Wu
    Department of Medicine, Veterans General Hospital, Taipei, Taiwan
    Mol Biol Evol 16:1622-32. 1999
  8. ncbi request reprint Mixed genotypes infection with hepatitis D virus
    J C Wu
    Department of Medicine, National Yang Ming University School of Medicine, Veterans General Hospital, Taipei, Taiwan, Republic of China
    J Med Virol 57:64-7. 1999
  9. ncbi request reprint Prevalence, implication, and viral nucleotide sequence analysis of GB virus-C/hepatitis G virus infection in acute fulminant and nonfulminant hepatitis
    J C Wu
    Department of Medicine, Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Med Virol 56:118-22. 1998
  10. doi request reprint Risk factors for early and late recurrence in hepatitis B-related hepatocellular carcinoma
    Jaw Ching Wu
    Department of Medical Research and Education, Taipei Veterans General Hospital, Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Hepatol 51:890-7. 2009

Detail Information

Publications105 found, 100 shown here

  1. pmc Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC
    Hsei Wei Wang
    Institute of Clinical Medicine, National Yang Ming University, NO, 201, Sec, 2, Shih Pai Rd, Taipei, Taiwan
    BMC Genomics 14:736. 2013
    ..We hypothesize that genes and etiological pathways are unique to young HCC (yHCC; ≤40 years old at diagnosis) patients. We therefore compared the gene expression profiles between yHCCs and HCCs from elderly patients...
  2. ncbi request reprint Characterization and phylogenetic analysis of a novel hepatitis D virus strain discovered by restriction fragment length polymorphism analysis
    J C Wu
    Department of Medicine, Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    J Gen Virol 79:1105-13. 1998
    ..3, 77.2 and 63.0%, respectively. Importantly, divergence was mostly seen in various regions related to replication or packaging. The novel isolates formed a monophyletic group (P < 0.05) and were most closely related to genotype II...
  3. ncbi request reprint "Defective" mutations of hepatitis D viruses in chronic hepatitis D patients
    Jaw Ching Wu
    Institute of Clinical Medicine, National Yang Ming University, Taipei 112, Taiwan, China
    World J Gastroenterol 11:1658-62. 2005
    ..To verify whether "defective" mutations existed in hepatitis D virus (HDV)...
  4. ncbi request reprint Functional and clinical significance of hepatitis D virus genotype II infection
    J C Wu
    Department of Medical Research and Education, Institute of Clinical Medicine, Taipei Veterans General Hospital, National Yang Ming University, Taiwan
    Curr Top Microbiol Immunol 307:173-86. 2006
    ..However, most patients with chronic HDV infection have low or undetectable hepatitis B virus DNA levels. During longitudinal follow-up, genotype I HDV is the most important determinant associated with survival...
  5. ncbi request reprint Spread of hepatitis E virus among different-aged pigs: two-year survey in Taiwan
    Jaw Ching Wu
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Med Virol 66:488-92. 2002
    ..S. belonged to the genotype 3 HEV in the U.S. The results suggest that HEV may infect pigs at an early growing stage and spread unnoticed among pigs and possibly across countries through trading...
  6. ncbi request reprint Clinical and epidemiological implications of swine hepatitis E virus infection
    J C Wu
    Institute of Clinical Medicine and Division of Gastroenterology, Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Med Virol 60:166-71. 2000
    ..Swine may be a reservoir of HEV and subclinical swine HEV infection may occur. Cross-reactivity of current anti-HEV assay may account for the high prevalence rate of anti-HEV in the general population in nonendemic areas...
  7. ncbi request reprint Recombination of hepatitis D virus RNA sequences and its implications
    J C Wu
    Department of Medicine, Veterans General Hospital, Taipei, Taiwan
    Mol Biol Evol 16:1622-32. 1999
    ..Therefore, recombination in these two segments may play an important role for HDV in the evasion of immunity...
  8. ncbi request reprint Mixed genotypes infection with hepatitis D virus
    J C Wu
    Department of Medicine, National Yang Ming University School of Medicine, Veterans General Hospital, Taipei, Taiwan, Republic of China
    J Med Virol 57:64-7. 1999
    ..One spouse had mixed infection and the other did not, corresponding to the index cases. In cases with mixed genotypes infections, the prevalence of the minor strain was less than 10% of the total colony population analyzed...
  9. ncbi request reprint Prevalence, implication, and viral nucleotide sequence analysis of GB virus-C/hepatitis G virus infection in acute fulminant and nonfulminant hepatitis
    J C Wu
    Department of Medicine, Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Med Virol 56:118-22. 1998
    ..The GBV-C/HGV clones from 21 patients with or without fulminant hepatitis belonged to group 3. No particular strain of GBV-C/HGV was associated with fulminant hepatitis...
  10. doi request reprint Risk factors for early and late recurrence in hepatitis B-related hepatocellular carcinoma
    Jaw Ching Wu
    Department of Medical Research and Education, Taipei Veterans General Hospital, Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Hepatol 51:890-7. 2009
    ..Herein we aimed to investigate the role of viral load in HCC recurrence following tumor resection...
  11. ncbi request reprint Comparison of recurrence after hepatic resection in patients with hepatitis B vs. hepatitis C-related small hepatocellular carcinoma in hepatitis B virus endemic area
    Yi Hsiang Huang
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
    Liver Int 25:236-41. 2005
    ..The carcinogenic mechanism of HBV and HCV is considered to be different. It is interesting to compare the recurrence after hepatic resection in patients with small HCC who were infected with HBV or HCV...
  12. ncbi request reprint Genotypes and viremia of hepatitis B and D viruses are associated with outcomes of chronic hepatitis D patients
    Chien Wei Su
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Gastroenterology 130:1625-35. 2006
    ..Genotypes and viremia of hepatitis D virus (HDV) and hepatitis B virus (HBV) may be associated with outcomes. This study evaluated the impact of viral genotypes and viremia on outcomes of dual HBV and HDV infection...
  13. ncbi request reprint Deterioration of hepatic functional reserve in patients with hepatocellular carcinoma after resection: incidence, risk factors, and association with intrahepatic tumor recurrence
    Teh Ia Huo
    Division of Gastroenterology, Department of Medicine, National Yang Ming University School of Medicine, Taipei Veterans General Hospital, 201 Sec 2 Shih Pai Road, 11217 Taipei, Taiwan
    World J Surg 28:258-62. 2004
    ..In conclusion, large HCCs are closely associated with hepatic decompensation in patients after resection. Tumor recurrence may predispose to the development of hepatic decompensation in these patients...
  14. ncbi request reprint Diabetes mellitus is a risk factor for hepatic decompensation in patients with hepatocellular carcinoma undergoing resection: a longitudinal study
    Teh Ia Huo
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Gastroenterol 98:2293-8. 2003
    ..The aim of this study was to assess the long-term impact of DM on the hepatic regenerative ability of HCC patients undergoing surgical resection...
  15. ncbi request reprint Survival benefit of cirrhotic patients with hepatocellular carcinoma treated by percutaneous ethanol injection as a salvage therapy
    Teh Ia Huo
    Dept of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taiwan, Republic of China
    Scand J Gastroenterol 37:350-5. 2002
    ..The safety and efficacy of percutaneous ethanol injection (PEI) as a salvage therapy in such patients is not clear...
  16. doi request reprint Risk factors for long-term prognosis in hepatocellular carcinoma after radiofrequency ablation therapy: the clinical implication of aspartate aminotransferase-platelet ratio index
    Wei Yu Kao
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Eur J Gastroenterol Hepatol 23:528-36. 2011
    ..This study aimed to evaluate the prognostic factors associated with the prognosis in patients with HCC undergoing RFA...
  17. ncbi request reprint Determination of the optimal model for end-stage liver disease score in patients with small hepatocellular carcinoma undergoing loco-regional therapy
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Liver Transpl 10:1507-13. 2004
    ..A lower MELD score may be suggested to be equivalent to the risk of short- and mid-term mortality in the cirrhosis group...
  18. ncbi request reprint Comparison of prognosis by viral etiology in patients with hepatocellular carcinoma after radiofrequency ablation
    Ping Hsien Chen
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Ann Hepatol 12:263-73. 2013
    ..However, prognosis of hepatitis B- and hepatitis C-related HCC after RFA remains debatable. This study aimed to assess the impact of viral etiology on the prognosis of HCC patients undergoing RFA...
  19. ncbi request reprint Proposal of a modified Child-Turcotte-Pugh scoring system and comparison with the model for end-stage liver disease for outcome prediction in patients with cirrhosis
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Liver Transpl 12:65-71. 2006
    ..By extending the score range according to the influence of the laboratory-derived variables, the modified CTP system has a better performance than the original system and is as efficient as the MELD for outcome prediction...
  20. ncbi request reprint Diabetes mellitus is a recurrence-independent risk factor in patients with hepatitis B virus-related hepatocellular carcinoma undergoing resection
    Teh Ia Huo
    Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Eur J Gastroenterol Hepatol 15:1203-8. 2003
    ..This study aimed to investigate the outcome in HCC patients undergoing resection with and without diabetes mellitus and the interaction with hepatitis B virus (HBV) and hepatitis C virus (HCV)...
  21. doi request reprint Predictive value of aspartate aminotransferase to alanine aminotransferase ratio for hepatic fibrosis and clinical adverse outcomes in patients with primary biliary cirrhosis
    Chien Wei Su
    Division of Gastroenterology, Department of Medicine, Taipei Veterans Genera Hospital, Taipei, Taiwan
    J Clin Gastroenterol 43:876-83. 2009
    ..043).Conclusions: AAR is a simple and reliable marker to assess liver function and hepatic fibrosis as well as to predict outcomes in PBC patients...
  22. ncbi request reprint Occurrence of cirrhosis-related complications is a time-dependent prognostic predictor independent of baseline model for end-stage liver disease score
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei, Taiwan, China
    Liver Int 26:55-61. 2006
    ..Many cirrhosis-related complications are indications for transplantation but are not included in MELD. This study investigated the impact of these complications on survival and association with MELD...
  23. doi request reprint Younger hepatocellular carcinoma patients have better prognosis after percutaneous radiofrequency ablation therapy
    Wei Yu Kao
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Clin Gastroenterol 46:62-70. 2012
    ..To evaluate the impact of age on the prognosis of patients with hepatocellular carcinoma (HCC) undergoing percutaneous radiofrequency ablation (RFA)...
  24. doi request reprint Impact of body mass index and viral load on liver histology in hepatitis B e antigen-negative chronic hepatitis B
    I Cheng Lee
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    Clin Nutr 30:647-52. 2011
    ..The impact of overweight and obesity on chronic hepatitis B (CHB) is unclear. This study was to examine the relationship among body mass index, viral load and liver histology in HBeAg-negative CHB...
  25. ncbi request reprint Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis
    Yi Shin Huang
    Division of Gastroenterology, Department of Medicine, and Chest Department, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Hepatology 35:883-9. 2002
    ..Regular monitoring of serum aminotransferase levels is mandatory in patients receiving antituberculosis treatment, especially in slow acetylators...
  26. ncbi request reprint Differential mechanism and prognostic impact of diabetes mellitus on patients with hepatocellular carcinoma undergoing surgical and nonsurgical treatment
    Teh Ia Huo
    Departments of Medicine, Surgery and Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Am J Gastroenterol 99:1479-87. 2004
    ..Diabetes mellitus (DM) is prevalent in patients with hepatocellular carcinoma (HCC) due to coexisting cirrhosis. This study aimed to investigate the long-term impact of DM on HCC patients and its underlying mechanism...
  27. ncbi request reprint The model for end-stage liver disease-based Japan Integrated Scoring system may have a better predictive ability for patients with hepatocellular carcinoma undergoing locoregional therapy
    Teh Ia Huo
    Faculty of Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer 107:141-8. 2006
    ..The objective of the current study was to investigate the performance of the modified MELD-based JIS system...
  28. doi request reprint Second primary cancers in patients with hepatocellular carcinoma: a nationwide cohort study in Taiwan
    Wen Chieh Wu
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Liver Int 33:616-23. 2013
    ..There has been no large-scale population-based study on the incidence and clinical manifestations of second primary cancer (SPC) after diagnosis of hepatocellular carcinoma (HCC)...
  29. doi request reprint Comparative analysis of noninvasive models to predict early liver fibrosis in hepatitis B e Antigen-negative Chronic Hepatitis B
    I Cheng Lee
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201 Shih Pai Road, Section 2, Taipei 112, Taiwan
    J Clin Gastroenterol 45:278-85. 2011
    ..An early marker predictive of liver fibrosis in hepatitis B e antigen (HBeAg)-negative CHB patients can alert clinicians to plan for treatment before disease progression...
  30. ncbi request reprint Evaluation of predictive value of CLIP, Okuda, TNM and JIS staging systems for hepatocellular carcinoma patients undergoing surgery
    Yi Hsiang Huang
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 20:765-71. 2005
    ..The purpose of the present paper was to compare the CLIP, Okuda, TNM and JIS staging systems for HCC patients undergoing surgery...
  31. ncbi request reprint Hepatitis C virus infection is a risk factor for tumor recurrence after resection of small hepatocellular carcinomas
    Teh Ia Huo
    Department of Medicine, Liver Unit, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, 112, Taipei, Taiwan, Republic of China
    World J Surg 28:787-91. 2004
    ..1 for all parameters). In conclusion, patients with small HCCs and concurrent HCV infection are at a high risk of tumor recurrence after resection...
  32. ncbi request reprint The predictive ability of serum alpha-fetoprotein for hepatocellular carcinoma is linked with the characteristics of the target population at surveillance
    Teh Ia Huo
    Institute of Pharmacology, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Surg Oncol 95:645-51. 2007
    ..The reported predictive accuracy of AFP for HCC widely varied. This study investigated the factors contributory to the heterogeneity of the ability of AFP to detect HCC...
  33. ncbi request reprint Incidence and risk factors for acute renal failure in patients with hepatocellular carcinoma undergoing transarterial chemoembolization: a prospective study
    Teh Ia Huo
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Liver Int 24:210-5. 2004
    ..Transarterial chemoembolization (TACE) is effective for hepatocellular carcinoma (HCC). Considerable amounts of radiocontrast agent are used for TACE and may induce renal dysfunction...
  34. ncbi request reprint Selective prognostic impact of serum alpha-fetoprotein level in patients with hepatocellular carcinoma: analysis of 543 patients in a single center
    Teh Ia Huo
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan, R O C
    Oncol Rep 11:543-50. 2004
    ..Its predictive ability is highly selective and dependent on treatment strategy and tumor size. Incorporation of serum AFP level into any prognostic prediction model should be based on its distinctive selective prognostic power...
  35. pmc Varied immunity generated in mice by DNA vaccines with large and small hepatitis delta antigens
    Yi Hsiang Huang
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Virol 77:12980-5. 2003
    ..These findings are important for the choice of a candidate HDV DNA vaccine in the future...
  36. ncbi request reprint Clinical characteristics and prognosis of hepatocellular carcinoma patients with paraneoplastic syndromes
    Jiing Chyuan Luo
    Division of Gastroenterology, Department of Medicine, Veterans General Hospital Taipei, National Yang Ming University School of Medicine, Taipei, Taiwan
    Hepatogastroenterology 49:1315-9. 2002
    ....
  37. doi request reprint Milan criteria, multi-nodularity, and microvascular invasion predict the recurrence patterns of hepatocellular carcinoma after resection
    Hung Hsu Hung
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201, Shih Pai Road, Sec 2, Taipei, 112, Taiwan
    J Gastrointest Surg 17:702-11. 2013
    ....
  38. ncbi request reprint Evaluation of the increase in model for end-stage liver disease (DeltaMELD) score over time as a prognostic predictor in patients with advanced cirrhosis: risk factor analysis and comparison with initial MELD and Child-Turcotte-Pugh score
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Hepatol 42:826-32. 2005
    ..We investigated the ability of DeltaMELD to predict the outcome of advanced cirrhosis and prospectively assessed the factors associated with increasing DeltaMELD...
  39. ncbi request reprint The sequential changes of the model for end-stage liver disease score correlate with the severity of liver cirrhosis in patients with hepatocellular carcinoma undergoing locoregional therapy
    Teh Ia Huo
    National Yang Ming University, School of Medicine, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    J Clin Gastroenterol 40:543-50. 2006
    ..This study investigated the correlation of sequential changes between MELD and Child-Turcotte-Pugh (CTP) scores in patients with hepatocellular carcinoma (HCC)...
  40. pmc Positive selection of hepatitis delta antigen in chronic hepatitis D patients
    Shen Yung Wang
    Department of Medical Research and Education, Taipei Veterans General Hospital, 201 Shih Pai Road, Sec 2, Taipei 11217, Taiwan
    J Virol 81:4438-44. 2007
    ..The discovery of immunogenic epitopes, especially cytotoxic-T-lymphocyte ligands, associated with chronic HDV infection may be crucial for further development of novel treatments or designs in vaccine for HDV superinfection...
  41. pmc Hepatitis B surface antigen levels and sequences of natural hepatitis B virus variants influence the assembly and secretion of hepatitis d virus
    Hsuan Hui Shih
    Department of Medical Research and Education, Taipei Veterans General Hospital, Institute of Clinical Medicine, National Yang Ming University, 201, Shih Pai Road, Sec 2, Taipei 11217, Taiwan
    J Virol 82:2250-64. 2008
    ..For an effective treatment of CHD, reduction of HBsAg production in addition to the suppression of HBV and HDV replication might be crucial...
  42. doi request reprint Pro-205 of large hepatitis delta antigen and Pro-62 of major hepatitis B surface antigen influence the assembly of different genotypes of hepatitis D virus
    Hsuan Hui Shih
    Department of Medical Research and Education, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Gen Virol 91:1004-12. 2010
    ..The presence of Pro-205 in genotype 1 HDV may account for its higher assembly efficiencies and wider distribution...
  43. ncbi request reprint Fever and infectious complications after percutaneous acetic acid injection therapy for hepatocellular carcinoma: incidence and risk factor analysis
    Teh Ia Huo
    Institute of Pharmacology and Faculty of Medicine, National Yang Ming University School of Medicine Departments of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    J Clin Gastroenterol 40:639-42. 2006
    ..Posttreatment fever (>37.5 degrees C) may occur owing to acetic acid-induced tumor necrosis, but its incidence and clinical significance are not clear...
  44. ncbi request reprint Limitation of the model for end-stage liver disease for outcome prediction in patients with cirrhosis-related complications
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Clin Transplant 20:188-94. 2006
    ..While early transplantation referral is recommended, these patients do not necessarily have a higher MELD score and could be down-staged in the MELD era...
  45. ncbi request reprint Proposal of a modified Cancer of the Liver Italian Program staging system based on the model for end-stage liver disease for patients with hepatocellular carcinoma undergoing loco-regional therapy
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Gastroenterol 101:975-82. 2006
    ..The model for end-stage liver disease (MELD) is a better prognostic predictor for cirrhotic patients compared to Child-Turcotte-Pugh (CTP) system, which is a parameter used in the CLIP model...
  46. ncbi request reprint Percutaneous injection therapy for hepatocellular carcinoma in patients with chronic renal insufficiency
    Teh Ia Huo
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Eur J Gastroenterol Hepatol 16:325-31. 2004
    ..5 mg/dl or above, is not known. This study compared the survival in HCC patients with and without CRI undergoing percutaneous injection therapy...
  47. ncbi request reprint Comparison of clinical manifestations and epidemiology between acute hepatitis A and acute hepatitis E in Taiwan
    Chien Wei Su
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taiwan
    J Gastroenterol Hepatol 17:1187-91. 2002
    ....
  48. doi request reprint Correlation between clinical indication for treatment and liver histology in HBeAg-negative chronic hepatitis B: a novel role of alpha-fetoprotein
    I Cheng Lee
    Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
    Liver Int 30:1161-8. 2010
    ..This study aimed to clarify this relationship and identify factors associated with liver histology...
  49. ncbi request reprint Prognostic significance of computed tomography scan-derived splenic volume in hepatocellular carcinoma treated with radiofrequency ablation
    Wen Chieh Wu
    Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
    J Clin Gastroenterol 46:789-95. 2012
    ..To evaluate the clinical implication of splenic volume measured by computed tomography (CT) scan in hepatocellular carcinoma (HCC) patients undergoing percutaneous radiofrequency ablation (RFA)...
  50. doi request reprint The effect of age on the long-term prognosis of patients with hepatocellular carcinoma after resection surgery: a propensity score matching analysis
    Chien Wei Su
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Arch Surg 147:137-44. 2012
    ..We aim to compare the clinicopathological features and prognoses between younger and older patients with HCC undergoing resection...
  51. doi request reprint A comparison of prognosis between patients with hepatitis B and C virus-related hepatocellular carcinoma undergoing resection surgery
    Wei Yu Kao
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    World J Surg 35:858-67. 2011
    ..This study aims to compare clinicopathologic features and prognoses between patients with hepatitis B- and hepatitis C-related HCC who underwent resection surgery...
  52. ncbi request reprint Different model for end-stage liver disease score block distributions may have a variable ability for outcome prediction
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Transplantation 80:1414-8. 2005
    ..However, it is not clear if the predictive accuracy of MELD is equally homogeneous in different distribution of MELD score blocks...
  53. ncbi request reprint Risk of hepatic failure after transcatheter arterial chemoembolization for hepatocellular carcinoma: predictive value of the monoethylglycinexylidide test
    Yi Shin Huang
    Department of Medicine, Taipei Veterans General Hospital, Taiwan
    Am J Gastroenterol 97:1223-7. 2002
    ..The purpose of this study was to evaluate whether the monoethylglycinexylidide test and other parameters might predict hepatic failure after TACE in HCC patients...
  54. ncbi request reprint Varied assembly and RNA editing efficiencies between genotypes I and II hepatitis D virus and their implications
    Sheng Chieh Hsu
    Institute of Microbiology and Immunology, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Hepatology 35:665-72. 2002
    ..094). In conclusion, genotype II HDV secretes fewer viral particles than genotype I HDV does, which in turn may reduce the extent of infection of hepatocytes and result in less severe hepatic inflammation...
  55. ncbi request reprint Characteristics of autoimmune hepatitis in Taiwan: the 11 years' experiences of a medical center
    Hui Chun Huang
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    Zhonghua Yi Xue Za Zhi (Taipei) 65:563-9. 2002
    ..Unlike in Western countries, autoimmune hepatitis (AIH) is an infrequent diagnosis in Taiwan. The clinical characteristics of AIH in this area are unclear. The aim of this study was to elucidate the clinical features of AIH in Taiwan...
  56. ncbi request reprint Changing seroepidemiology of hepatitis B, C, and D virus infections in high-risk populations
    Teh Ia Huo
    Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital and Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taiwan
    J Med Virol 72:41-5. 2004
    ..Male prostitutes and immigrant prostitutes are new "high-risk" populations and may become a reservoir for disease transmission...
  57. ncbi request reprint The model for end-stage liver disease based cancer staging systems are better prognostic models for hepatocellular carcinoma: a prospective sequential survey
    Teh Ia Huo
    Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Am J Gastroenterol 102:1920-30. 2007
    ....
  58. ncbi request reprint Percutaneous ablation therapy for hepatocellular carcinoma: current practice and future perspectives
    Teh Ia Huo
    National Yang Ming University School of Medicine, Taiwan, ROC
    J Chin Med Assoc 68:155-9. 2005
    ..While newer anti-tumor therapies with improved efficacy are needed, information about a more rational approach to the use of existing therapeutic options may help to enhance treatment strategies for HCC...
  59. ncbi request reprint Survival impact of delayed treatment in patients with hepatocellular carcinoma undergoing locoregional therapy: is there a lead-time bias?
    Teh Ia Huo
    Institute of Pharmacology, National Yang Ming University School of Medicine, Taipei, Taiwan
    Scand J Gastroenterol 42:485-92. 2007
    ..The objective of this study was to investigate whether patients with delayed locoregional therapy for HCC truly have a shortened survival from the time of diagnosis...
  60. doi request reprint Hepatic resection can provide long-term survival of patients with non-early-stage hepatocellular carcinoma: extending the indication for resection?
    Wen Tsan Chang
    Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Surgery 152:809-20. 2012
    ..This study aimed to identify factors that affect outcome of patients with Barcelona Clinical Liver Cancer Classification (BCLC) stage B or stage C HCC after hepatic resection...
  61. doi request reprint Generation of cytotoxicity against hepatitis delta virus genotypes and quasispecies by epitope modification
    Yi Hsiang Huang
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201 Shih Pai Road, Sec 2, Taipei 112, Taiwan
    J Hepatol 50:779-88. 2009
    ..The aim of this study was to enhance the immune response against varied sequences within the HDV quasispecies in an attempt to control chronic delta hepatitis...
  62. pmc Interaction and replication activation of genotype I and II hepatitis delta antigens
    Sheng Chieh Hsu
    Institutes of Microbiology and Immunology, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Virol 78:2693-700. 2004
    ..In conclusion, genotype has no effect on HDAg interaction and genotype per se only partly predicts how much the HDAg-S of an HDV isolate affects the replication of a second HDV isolate...
  63. doi request reprint Risk of hepato-biliary cancer after cholecystectomy: a nationwide cohort study
    Wei Yu Kao
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201 Shih Pai Road, Sec 2, Taipei, 112, Taiwan
    J Gastrointest Surg 17:345-51. 2013
    ..Epidemiologic studies have identified cholecystectomy as a possible risk factor for cancers in Western countries. The aim of this study was to estimate the risk of hepato-biliary cancer after cholecystectomy in Taiwan...
  64. doi request reprint Survival rates are comparable after radiofrequency ablation or surgery in patients with small hepatocellular carcinomas
    Hung Hsu Hung
    Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Clin Gastroenterol Hepatol 9:79-86. 2011
    ..Differences in efficacy of radiofrequency ablation (RFA) and surgical resection (SR) are not clear for patients with hepatocellular carcinoma (HCC)...
  65. ncbi request reprint The role of transcatheter arterial embolization in patients with resectable hepatocellular carcinoma: a nation-wide, multicenter study
    Yi Hsiang Huang
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
    Liver Int 24:419-24. 2004
    ..The role of transcatheter arterial embolization (TAE) for patients with resectable hepatocellular carcinoma (HCC) is controversial. Analyzing a cohort of nation-wide data can delineate the beneficial effect of TAE for those patients...
  66. doi request reprint Natural history and prognostic factors of primary biliary cirrhosis in Taiwan: a follow-up study up to 18 years
    Chien Wei Su
    Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
    Liver Int 28:1305-13. 2008
    ..The natural history of primary biliary cirrhosis (PBC) has been little studied in Asia. We conducted a Taiwanese cohort study on the natural history of PBC and analysed the prognostic factors...
  67. ncbi request reprint Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis
    Yi Shin Huang
    Division of Gastroenterology, Department of Medicine, and the Chest Department, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Hepatology 37:924-30. 2003
    ..In conclusion, CYP 2E1 genetic polymorphism may be associated with susceptibility to antituberculosis drug-induced hepatitis...
  68. ncbi request reprint Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma
    Yi Shin Huang
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Gastroenterol 98:1417-22. 2003
    ..The aim of this study was to evaluate the relationship of NAT2 genetic polymorphisms with hepatocellular carcinoma (HCC), with special reference to the interaction of dietary habits...
  69. doi request reprint Successful radiofrequency ablation therapy for hepatocellular carcinoma in a male patient with early stage primary biliary cirrhosis and positive serum hepatitis B core antibody
    Chien Wei Su
    Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    J Chin Med Assoc 71:40-4. 2008
    ..This case report demonstrates that HCC can arise from precirrhotic PBC and can be successfully treated by RFA. Regular surveillance for HCC is warranted for all patients with PBC, irrespective of stage...
  70. ncbi request reprint Thrombocytosis: a paraneoplastic syndrome in patients with hepatocellular carcinoma
    Shinn Jang Hwang
    Departmetn of Family Medicine, Taipei Veterans General Hospital and National Yang Ming Univerity School of Medicine, Taiwan, China
    World J Gastroenterol 10:2472-7. 2004
    ..Thrombocytosis was reported in children with hepatoblastoma. The aims of this study were to evaluate the prevalence and clinical significance of thrombocytosis in HCC patients and its relationships with serum thrombopoietin (TPO)...
  71. pmc Hepatitis D virus isolates with low replication and epithelial-mesenchymal transition-inducing activity are associated with disease remission
    Hsuan Hui Shih
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan
    J Virol 86:9044-54. 2012
    ..It is concluded that in chronically infected patients, HDV quasispecies with a low replication capacity and low EMT activity are associated with disease remission...
  72. doi request reprint Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma
    Muh Hwa Yang
    Institutes of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
    Hepatology 50:1464-74. 2009
    ..Twist and Snail were independently regulated, but exerted an additive inhibitory effect to suppress E-cadherin transcription...
  73. pmc Inverse association between hepatitis B virus infection and fatty liver disease: a large-scale study in populations seeking for check-up
    Yuan Lung Cheng
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    PLoS ONE 8:e72049. 2013
    ....
  74. ncbi request reprint HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis
    Keng Hsin Lan
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei 11217, Taiwan, Republic of China
    Oncogene 21:4801-11. 2002
    ....
  75. doi request reprint Hepatocellular carcinoma with presentation of budd-Chiari syndrome
    Wei Yu Kao
    Division of Gastroenterology, Department of Medicine, Taipei, Taiwan, ROC
    J Chin Med Assoc 73:93-6. 2010
    ..Regular follow-up of chronic hepatitis B, including biochemical and sonography surveillance, should be performed...
  76. ncbi request reprint Severe bone marrow depression induced by an anticancer herb Cantharanthus roseus
    Ming Ling Wu
    Division of Clinical Toxicology, Department of Medicine, Taipei Veterans General Hospital and School of Medicine, National Yang Ming University, No 201 Sec 2, Shih Pai Rd 11217, Taipei, Taiwan
    J Toxicol Clin Toxicol 42:667-71. 2004
    ..This case report demonstrated possible effect of oral dose of vinca alkaloids and also hinted that all the substrates and inhibitors of CYP 3A4 have propensity to interfere with metabolism of vinca alkaloids...
  77. ncbi request reprint Seroprevalence of hepatitis E virus infection among institutionalized psychiatric patients in Taiwan
    Pin Nan Cheng
    Department of Internal Medicine, National Cheng Kung University Hospital, Taipei, Taiwan, ROC
    J Clin Virol 38:44-8. 2007
    ..Hepatitis E virus infection (HEV) remains unclear in institutionalized psychiatric patients...
  78. doi request reprint Clinical correlates and diagnostic utility of osmophobia in migraine
    Yen Feng Wang
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    Cephalalgia 32:1180-8. 2012
    ..Osmophobia is an under-investigated associated symptom in migraine...
  79. doi request reprint Systemic amyloidosis manifesting as a rare cause of hepatic failure
    Hung Hsu Hung
    Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan, R O C
    J Chin Med Assoc 73:161-5. 2010
    ..Clinicians should be aware of this rare but potentially lethal presentation and arrange appropriate treatment promptly...
  80. doi request reprint Chronological changes in renal vascular reactivity in portal hypertensive rats
    Chiao Lin Chuang
    Division of General Medicine, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Eur J Clin Invest 43:267-76. 2013
    ..However, the sequences of altered renal haemodynamics have never been described. This study aimed to explore the evolution of renal vascular hyporeactivity and associated mechanisms during portal hypertension...
  81. pmc Queckenstedt's test affects more than jugular venous congestion in rat
    Chi Hsiang Chou
    Department of Neurology, Taichung Veterans General Hospital, Taichung, Taiwan
    PLoS ONE 8:e59409. 2013
    ..Since this model revealed significant differences between the manual Q-test and bilateral CJV clipping, the finding should be taken into account in future studies on the Q-test in SD rats...
  82. doi request reprint Queckenstedt's test headache response is associated with increased jugular venous flow volume during migraine attack
    Chi Hsiang Chou
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    Ultrasound Med Biol 37:23-8. 2011
    ..422). Thus, the IJV flow volume was increased during migraine attacks and was directly related to the Q-test response. It may be used as a research tool for peripheral sensitization during acute migraine attacks...
  83. ncbi request reprint The lifetime cost of hepatocellular carcinoma : a claims data analysis from a medical centre in Taiwan
    Hui Chu Lang
    Institute of Hospital and Health Care Administration, National Yang Ming University, Taipei, Taiwan
    Appl Health Econ Health Policy 6:55-65. 2008
    ..Hepatocellular carcinoma (HCC) is the second most common cancer in Taiwan. For males in Taiwan, it is the most dangerous cancer, with both the highest incidence and mortality rate...
  84. ncbi request reprint Genetic distinctions and clinical characteristics of type 1 autoimmune hepatitis in Taiwan
    Hui Chun Huang
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Hepatogastroenterology 55:605-8. 2008
    ..This study aims to evaluate the HLA characteristics of Taiwanese AIH patients...
  85. doi request reprint Comparison of four model for end-stage liver disease-based prognostic systems for cirrhosis
    Teh Ia Huo
    Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Liver Transpl 14:837-44. 2008
    ..Patients with SBP have a higher MELD-derived score. Future studies are warranted to define the optimal MELD-based prognostic model for cirrhosis...
  86. doi request reprint Magnetic resonance angiography in reversible cerebral vasoconstriction syndromes
    Shih Pin Chen
    Institute of Clinical Medicine, Fu Jen Catholic University, Taipei, Taiwan
    Ann Neurol 67:648-56. 2010
    ..To investigate the evolution and clinical significance of vasoconstriction on magnetic resonance angiography (MRA) in patients with reversible cerebral vasoconstriction syndromes (RCVS)...
  87. ncbi request reprint Identification of novel HLA-A*0201-restricted CD8+ T-cell epitopes on hepatitis delta virus
    Yi Hsiang Huang
    Institute of Clinical Medicine, National Yang Ming University, Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201 Shih Pai Road, Sec 2, Taipei 112, Taiwan, Republic of China
    J Gen Virol 85:3089-98. 2004
    ..Evoking CTL responses to HDV may be an alternative approach to controlling HDV viraemia in patients with chronic hepatitis delta...
  88. ncbi request reprint Analysis of humoral immunity of hepatitis D virus DNA vaccine generated in mice by using different dosage, gene gun immunization, and in vivo electroporation
    Yih Tsong Shiau
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
    J Chin Med Assoc 69:7-13. 2006
    ..Whether the low humoral immunity of L-HDAg DNA vaccine is due to inadequate dosage or can be ameliorated by other modes of immunization needs further evaluation...
  89. ncbi request reprint Zafirlukast-induced acute hepatitis
    Chien Wei Su
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan ROC
    Zhonghua Yi Xue Za Zhi (Taipei) 65:553-6. 2002
    ..If drug-induced hepatitis is suspected, medication should be discontinued immediately to prevent further liver injury...
  90. ncbi request reprint Comparison of staging systems for HCC: one more positive answer or mission impossible?
    Teh Ia Huo
    Hepatology 42:238-9. 2005
  91. ncbi request reprint Effects of multiple virus coinfections on disease progression in HIV-positive patients
    Biehuoy Shieh
    Department of Biochemistry, Chung Shan Medical University, Taichung, Taiwan, ROC
    Intervirology 46:105-13. 2003
    ....
  92. ncbi request reprint Screening for hepatocellular carcinoma in high-risk patients: Western versus Eastern virus
    Teh Ia Huo
    Hepatology 38:269; author reply 270. 2003
  93. ncbi request reprint Role of locoregional therapy for hepatocellular carcinoma before liver transplantation: answer or myth?
    Teh Ia Huo
    Liver Transpl 12:1560; author reply 1561. 2006
  94. ncbi request reprint Outcomes of patients with seroclearance of HBsAg: different facets of the truth
    Teh Ia Huo
    Gastroenterology 125:274-5; author reply 275. 2003
  95. ncbi request reprint Does hepatitis B viral load determine the outcome of patients with hepatocellular carcinoma undergoing chemotherapy?
    Teh Ia Huo
    Hepatology 46:1665-6; author reply 1666. 2007
  96. ncbi request reprint Staging for hepatocellular carcinoma: look for a perfect classification system
    Teh Ia Huo
    J Hepatol 40:1041-2; author reply 1042-3. 2004
  97. ncbi request reprint Secular trends and geographic variations of hepatitis B virus and hepatitis C virus-associated hepatocellular carcinoma in Taiwan
    Sheng Nan Lu
    Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Int J Cancer 119:1946-52. 2006
    ..Prevention of new HCV infection and the treatment of chronic hepatitis C should be the primary goals, which will result in better control of HCC in the future, even in an HBV-endemic area like Taiwan...
  98. ncbi request reprint Hepatitis after arterial embolization for hepatocellular carcinoma: Viral reactivation or ischemia?
    Teh Ia Huo
    Hepatology 43:1400-1. 2006
  99. ncbi request reprint Ethanol injection versus radiofrequency ablation for hepatocellular carcinoma: which is better?
    Teh Ia Huo
    Gastroenterology 128:806-7. 2005
  100. ncbi request reprint MELD in liver transplantation: the da Vinci code for the Holy Grail?
    Teh Ia Huo
    J Hepatol 42:477-8; author reply 478-9. 2005
  101. ncbi request reprint Molecular epidemiological and clinical aspects of hepatitis D virus in a unique triple hepatitis viruses (B, C, D) endemic community in Taiwan
    Sheng Nan Lu
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    J Med Virol 70:74-80. 2003
    ..HBV and HDV lapsed into a remission or nonreplicative phase in most cases, and HCV acted as a dominant factor in triple viral-infected individuals. Only the presence of HCV RNA was associated with elevated ALT values, but not HBV or HDV...