Research Topics
Species | Ching Liang LuSummaryAffiliation: Taipei Veterans General Hospital Country: Taiwan Publications
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Detail Information
Publications
Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in ratsChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Gastroenterology 137:1040-50. 2009..We examined the role of sex hormones in a VH model without colonic inflammation...
Gender difference on the symptoms, health-seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II-based survey in an apparent healthy adult Chinese population in TaiwanC L Lu
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Aliment Pharmacol Ther 21:1497-505. 2005..Little is known about the gender effect on irritable bowel syndrome in Asia...
Impaired gastric myoelectricity in patients with chronic pancreatitis: role of maldigestionChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, China
World J Gastroenterol 11:372-6. 2005..To investigate whether gastric myoelectrical activity was impaired in patients with chronic pancreatitis (CP) and to explore the role of pancreatic enzyme in regulating gastric myoelectrical activity...
Increasing trend of the incidence of esophageal squamous cell carcinoma, but not adenocarcinoma, in TaiwanChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Cancer Causes Control 21:269-74. 2010..59% (P = 0.30) in female. In Taiwan, the incidence of ESCC significantly increased from 1979 to 2003, whereas the incidence of EA remained unchanged. Although EA incidence has not recently increased, it could in the future...
Changes of the neuropeptides content and gene expression in spinal cord and dorsal root ganglion after noxious colorectal distensionChing Liang Lu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, 11217, Taiwan
Regul Pept 131:66-73. 2005..In the absence of visceral inflammation, the aforementioned neuropeptides are important mediators in the processing of visceral pain/hypersensitivity...
Estrogen rapidly modulates mustard oil-induced visceral hypersensitivity in conscious female rats: A role of CREB phosphorylation in spinal dorsal horn neuronsChing Liang Lu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Rd, Taipei, Taiwan 11217
Am J Physiol Gastrointest Liver Physiol 292:G438-46. 2007....
Irritable bowel syndrome and negative appendectomy: a prospective multivariable investigationChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine, National Yang Ming University, Taipei, Taiwan 11217
Gut 56:655-60. 2007..To examine prospectively whether irritable bowel syndrome (IBS) or other variables-that is, psychiatric profiles, health-related quality of life (HRQoL) and clinical features-are associated with negative appendectomy (NA)...
Social and medical impact, sleep quality and the pharmaceutical costs of heartburn in TaiwanC L Lu
Division of Gastroenterology, Taipei Veterans General Hospital, and School of Medicine, National Yang Ming University, Taipei, Taiwan
Aliment Pharmacol Ther 22:739-47. 2005..Little is known about the social and medical burdens of heartburn in Asia...
Dexamethasone inhibits epidermal growth factor-stimulated gastric epithelial cell proliferationJiing Chyuan Luo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan 11217
J Pharmacol Exp Ther 320:687-94. 2007....
Incidence and possible risk factors for clinical upper gastrointestinal events in patients taking selective cyclooxygenase-2 inhibitors: A prospective, observational, cohort study in TaiwanKuo Wei Hsiang
Department of Medicine, Taipei Veterans General Hospital, Taiwan, R O C
Clin Ther 32:1294-303. 2010..However, the risk factors for clinical upper GI events (symptomatic ulcers and ulcer complications) in COX-2 inhibitor users have been rarely evaluated in the past...
Electrogastrographic characteristics in subjects with stomach remnantHsing Feng Lee
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan
J Gastroenterol Hepatol 25:339-44. 2010..Slow wave (SW) is an essential component in mediating stomach motility. The purpose of the present study was to investigate the SW characteristics in subjects with stomach remnant...
Undisturbed water gastric emptying in patients of stomach cancerFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine National Yang Ming University, Taipei, Taiwan, Republic of China
Hepatogastroenterology 51:1219-24. 2004..It is of interest whether the stomach motility in gastric cancer patients may be altered. We employed a homemade applied potential tomographic system to study the features of water gastric emptying in gastric cancer patients...
Fasting and postprandial small intestinal slow waves non-invasively measured in subjects with total gastrectomyFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan
J Gastroenterol Hepatol 22:247-52. 2007..The aims of this study were to determine the origin of 3 cycles per min (cpm) slow wave recorded via electrogastrogram (EGG) and the characteristics of putative small intestinal slow waves in TG subjects...
Dexamethasone inhibits tumor necrosis factor-alpha-stimulated gastric epithelial cell migrationJiing Chyuan Luo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
J Chin Med Assoc 72:509-14. 2009..We evaluated whether dexamethasone inhibited TNF-alpha-stimulated gastric epithelial cell migration using a rat normal gastric epithelial cell line (RGM-1)...
Efficacy of dioctahedral smectite in treating patients of diarrhea-predominant irritable bowel syndromeFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine, National Yang Ming University, Taipei, Taiwan
J Gastroenterol Hepatol 22:2266-72. 2007..The aim of this study was to determine DS efficacy on patients with diarrhea-predominant irritable bowel syndrome (D-IBS in a phase III-, 8-week-randomized, double-blind, placebo-controlled trial...
Response of blood endothelin-1 and nitric oxide activity in duodenal ulcer patients undergoing Helicobacter pylori eradicationFull Young Chang
Chief, Division of Gastroenterology, Taipei Veterans General Hospital, 201, Section 2, Shih Pai Road, Taipei 112, Taiwan, China
World J Gastroenterol 11:1048-51. 2005..To investigate the effect of Helicobacter pylori eradication on endothelin-1 (ET-1) and nitric oxide (NO) in duodenal ulcer (DU) patients...
Spinal microglia initiate and maintain hyperalgesia in a rat model of chronic pancreatitisPei Yi Liu
Institute of Brain Science, National Yang Ming University, Taipei, Taiwan
Gastroenterology 142:165-173.e2. 2012..We investigated whether activated microglia in the thoracic spinal cord contribute to chronic pain in a rat model of CP...
Rat small intestinal transit is independent of glucose consumption in the strenuous exerciseFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan, Republic of China
Chin J Physiol 49:169-73. 2006..Glucose utilization and lactate accumulation after the strenuous exercise may not directly mediate small intestinal motility...
Effect of Helicobacter pylori eradicated therapy on water gastric emptying in patients with active duodenal ulcerFull-Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 18:1250-6. 2003..CONCLUSIONS: Water GE of active DU patients ranges from enhanced to delayed, while an effective H. pylori triple therapy is useful not only for healing ulcers, but also for restoring abnormal GE...
Enhanced affect/cognition-related brain responses during visceral placebo analgesia in irritable bowel syndrome patientsHsing Feng Lee
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Pain 153:1301-10. 2012..The visceral placebo analgesia produced heightened activity in affective/cognitive brain regions in IBS patients...
Interaction of carbohydrate metabolism and rat liquid gastric emptying in sustained runningFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 21:831-6. 2006..It is unknown whether the carbohydrate metabolism of runners can influence gastric emptying (GE). Using a running rat model, the present study explored the impact of exercise/carbohydrate metabolism on liquid GE...
The clinical significances of irritable bowel syndrome in TaiwanFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, and Institute of Brain Science, National Yang Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 26:102-5. 2011..According to the Rome III definition, irritable bowel syndrome (IBS) has been a biopsychosocial dysfunction. We tried to know whether the IBS clinical manifestations were comparable to other countries...
Neuronal correlates in the modulation of placebo analgesia in experimentally-induced esophageal pain: a 3T-fMRI studyHsueh Chieh Lu
Department of Internal Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
Pain 148:75-83. 2010..VLPFC activation during the anticipation of placebo analgesia suggests top-down control in the modulation of pain experience...
Growth factors expression in patients with erosive esophagitisJiing Chyuan Luo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Transl Res 152:81-7. 2008..05). The study found that HGF, HGFR, EGF, VEGF, and, COX-2 are activated in the injured mucosa of EE patients; their activation might be involved in mucosal repair and ulcer healing of EE...
Gastric mucosal injury in systemic lupus erythematosus patients receiving pulse methylprednisolone therapyJiing Chyuan Luo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan
Br J Clin Pharmacol 68:252-9. 2009..We investigated whether very high-dose steroids caused gastric mucosal injury in systemic lupus erythematous (SLE) patients and evaluated the possible risk factors for mucosal injury...
Placebo effect in patients with irritable bowel syndromeChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital Institute of Brain Science, National Yang Ming University Taipei, Taiwan
J Gastroenterol Hepatol 26:116-8. 2011..Further promotion and integration of laboratory and clinical research are encouraged to advance the understanding of placebo mechanisms in IBS patients...
Stomach myoelectrical response of patients with gastroesophageal reflux disease receiving omeprazole treatmentFull-Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine National Yang Ming University, and Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
J Gastroenterol Hepatol 18:1399-406. 2003..Effective omeprazole treatment only improves the postprandial myoelectrical regularity, whereas abnormal EGG parameters remain impaired...
Dexamethasone inhibits basic fibroblast growth factor-stimulated gastric epithelial cell proliferationJiing Chyuan Luo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Biochem Pharmacol 76:841-9. 2008....
Irritable bowel syndrome in the 21st century: perspectives from Asia or South-east AsiaFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 22:4-12. 2007..In conclusion, Western recommended criteria clearly diagnose Asian IBS and many factors are mutual leading to IBS. Current IBS treatments remain useful but additional reeducation for medical professionals appears to be needed...
Reduced hippocampal glutamate-glutamine levels in irritable bowel syndrome: preliminary findings using magnetic resonance spectroscopyDavid M Niddam
Brain Research Center, National Yang Ming University, Taipei, Taiwan, ROC
Am J Gastroenterol 106:1503-11. 2011....
The role of cholecystokinin 1 receptor in prolactin inhibited gastric emptying of male ratFull Young Chang
Environmental Heath and Safety Office and Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
J Neurogastroenterol Motil 18:385-90. 2012..Present study attempted to determine whether both peptides interacted on the male rat GE, particularly the role of putative CCK1 receptor...
The evaluation of otilonium bromide treatment in asian patients with irritable bowel syndromeFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
J Neurogastroenterol Motil 17:402-10. 2011..However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients...
Eosinophilic esophagitis in an asymptomatic ChineseHsueh Chieh Lu
Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
J Chin Med Assoc 71:362-4. 2008..The unusual feature of the current case was the lack of symptoms. This case confirms that a dense infiltration of esophageal eosinophils can occur asymptomatically...
The current prevalence of irritable bowel syndrome in AsiaFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
J Neurogastroenterol Motil 16:389-400. 2010..In conclusions, current Asia IBS prevalence is at least equal to the Western countries. Female predominant prevalence in Asia is common but not uniquely existed, while the proportions of IBS subtypes are too variable to find a rule...
Treatment of irritable bowel syndrome using complementary and alternative medicineFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan, R O C
J Chin Med Assoc 72:294-300. 2009..Apart from conventional medications, CAM may be considered individually as a supplement or alternative to treat IBS patients that is at least equal in effect to placebo if patients do not exhibit any intolerable or serious side effects...
Silent peptic ulcer disease: frequency, factors leading to "silence," and implications regarding the pathogenesis of visceral symptomsChing-Liang Lu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
Gastrointest Endosc 60:34-8. 2004..These findings may contribute to the understanding of the pathogenesis in the visceral symptoms of peptic ulcer disease...
Impaired gastric myoelectrical activity in patients with Parkinson's disease and effect of levodopa treatmentChing-Liang Lu
Division of Gastroenterology and Neurology Department, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan
Dig Dis Sci 49:744-9. 2004..These abnormalities may be partially corrected with levodopa treatment in the fed state...
Hiccup: mystery, nature and treatmentFull Young Chang
Environmental Health and Safety Office, Division of Gastroenterology, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan
J Neurogastroenterol Motil 18:123-30. 2012..The lesion may need to be localized correctly for ablative treatment in patients with intractable hiccup. Apart from lesion ablation, drugs acting on reflex arc may be effective, while some other conventional measures may also be tried...
Acute urinary retention in the elderly: an unusual presentation of appendicitis with a high perforation riskChun-Chu Liu
Department of Internal Medicine, Koo Foundation, Sun Yat-Sen Cancer Center, Taipei, Taiwan
Gerontology 48:387-91. 2002..When confronted with a geriatric patient presenting with AUR, one should entertain an alternative diagnosis and a reexamination of the patient is mandatory...
Prevalence and health/social impacts of functional dyspepsia in Taiwan: a study based on the Rome criteria questionnaire survey assisted by endoscopic exclusion among a physical check-up populationChing-Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Scand J Gastroenterol 40:402-11. 2005..The newly defined Rome II criteria diminish the chance of co-existence of FD and IBS. Further FD classification by the main symptoms appears of limited clinical usefulness...
Esomeprazole tablet vs omeprazole capsule in treating erosive esophagitisChih-Yen Chen
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine, National Yang-Ming University, No. 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan, China
World J Gastroenterol 11:3112-7. 2005..CONCLUSION: Esomeprazole 40 mg is an effective and safe drug at least comparable to omeprazole in treating Chinese EE patients...
Infrared spectrometry based 13C-octanoic acid breath test in measuring human solid gastric emptyingChih-Ping Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 18:41-6. 2003..CONCLUSIONS: 13C-octanoic acid breath test determined by NDIRS is a simple, non-invasive and reliable measurement, which may provide an 'office-based' tool to detect solid GE...
Unchanging trend of adenocarcinoma of the esophagus and gastric cardia in Taiwan: a 15-year experience in a single centerShen-Shong Chang
Division of Gastroenterology, Cancer Center, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taiwan
Dig Dis Sci 47:735-40. 2002..Although gastroesophageal reflux disease is common here, its definite pathogenesis leading to esophageal adenocarcinoma or gastric cardia carcinoma remains unresolved...
Is somatosensory cortex activated during proximal stomach stimulation and the role of insula in visceral painChing-Liang Lu
Gastroenterology 128:1529-30; author reply 1530-1. 2005
Spontaneous cholecystocutaneous fistula presenting with a cellulitis and portal vein thrombosisShen-Shong Chang
J Clin Gastroenterol 34:99-100. 2002
