Research Topics
Genomes and GenesSpecies | Jen Ping HwangSummaryAffiliation: Taipei Veterans General Hospital Country: Taiwan Publications
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Detail Information
Publications
Cortical and subcortical abnormalities in late-onset depression with history of suicide attempts investigated with MRI and voxel-based morphometryJen Ping Hwang
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
J Geriatr Psychiatry Neurol 23:171-84. 2010....
The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depressionJen Ping Hwang
Department of Psychiatry, Taipei Veterans General Hospital, No 201, Shih Pai Road, Sec 2, 11217 Taipei, Taiwan
Neurobiol Aging 27:1834-7. 2006..001). The BDNF polymorphism did not affect age-of-onset, depression severity, cognitive function or suicidal attempt history. The results suggest that the BDNF Val66Met polymorphism is a relevant risk factor for geriatric depression...
Association of APOE genetic polymorphism with cognitive function and suicide history in geriatric depressionJen Ping Hwang
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
Dement Geriatr Cogn Disord 22:334-8. 2006..021) and an increased suicide attempt history (p = 0.012). The APOE genotype may contribute to cognitive performance and suicidality in geriatric depression, rather than being a specific risk factor for the disorder...
Association of MTHFR C677T polymorphism with loneliness but not depression in cognitively normal elderly malesWen Hsuan Lan
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
Neurosci Lett 521:88-91. 2012..Our findings suggest that MTHFR C677T polymorphism may be linked more to loneliness than depression in the cognitively normal elderly males, and may be implicated in the pathophysiology of late-life depression in relation to MTHFR genes...
Gene-gene interactions of the brain-derived neurotrophic-factor and neurotrophic tyrosine kinase receptor 2 genes in geriatric depressionEugene Lin
Vita Genomics, Inc, Taipei, Taiwan
Rejuvenation Res 12:387-93. 2009..Analyses using logistic regression models confirmed the gene-gene interactions. The results suggest that the BDNF and NTRK2 genes may contribute to the risk of geriatric depression independently and in an interactive manner...
Heterozygote advantage of the MTHFR C677T polymorphism on specific cognitive performance in elderly Chinese males without dementiaShih Jen Tsai
Department of Psychiatry, Taipei Veterans General Hospital, Taiwan, ROC
Dement Geriatr Cogn Disord 32:159-63. 2011..We designed the present study to investigate whether this functional polymorphism may affect global and specific cognitive functions in older Chinese males without dementia...
Interleukin-1 beta -511C/T genetic polymorphism is associated with age of onset of geriatric depressionJen Ping Hwang
Department of Psychiatry, Taipei Veterans General Hospital, No 201, Shih Pai Road, Sec 2, Taipei, 11217, Taiwan
Neuromolecular Med 11:322-7. 2009..Further study is warranted to confirm this finding and to assess its generalization to other ethnic groups...
Severe cardiovascular side effects of olanzapine in an elderly patient: case reportTien Wen Lee
Department of Psychiatry, Tzu Chi General Hospital, Hualien, Taiwan, Republic of China
Int J Psychiatry Med 33:399-401. 2003..We hereby report an aged case that presented with conscious depression, bradycardia, hypotension, miosis and hypothermia. Olanzapine was thought to be the offending agent. His condition improved with supportive therapy...
Chinese demented inpatients admitted following a suicide attempt: a case seriesChia Fen Tsai
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
Int J Geriatr Psychiatry 22:1106-9. 2007..Suicide attempt is rarely reported in dementia. This study explores the clinical and phenomenological aspects as well as the treatment of Chinese demented patients who have attempted suicide...
Clinical and phenomenological comparisons of delusional and non-delusional major depression in the Chinese elderlyTien-Wen Lee
Department of Psychiatry, Veterans General Hospital-Taipei, Taipei, Taiwan, ROC
Int J Geriatr Psychiatry 18:486-90. 2003..CONCLUSION: Our findings were grossly concordant with previous Western reports, and highlight the importance of identifying the delusional subgroup of depressive patients because of the higher risk of suicide attempt...
