Research Topics
| Chuang C ChiuehSummaryAffiliation: Taipei Medical University Country: Taiwan Publications
| Collaborators
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Detail Information
Publications
Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expressionTsugunobu Andoh
Department of Applied Pharmacology, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Japan
Ann N Y Acad Sci 962:1-7. 2002..These results suggest that *NO-cGMP-PKG signaling pathway plays an important role in the preconditioning-induced neuroprotection, and perhaps cardioprotection, against oxidative stress...
Induction of thioredoxin and mitochondrial survival proteins mediates preconditioning-induced cardioprotection and neuroprotectionChuang C Chiueh
School of Pharmacy, Taipei Medical University, 250 Wu Hsing Street, Taipei 100, Taiwan
Ann N Y Acad Sci 1042:403-18. 2005..Preconditioning-induced adaptive tolerance may be signaling through a cGMP-dependent induction of cytosolic redox protein Trx1 and subsequently mitochondrial proteins such as Bcl-2, MnSOD, and perhaps Trx2 or HSP70...
Roles of thioredoxin in nitric oxide-dependent preconditioning-induced tolerance against MPTP neurotoxinChuang C Chiueh
School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan, ROC
Toxicol Appl Pharmacol 207:96-102. 2005..It is concluded that Trx plays a pivotal role in ()NO-dependent preconditioning hormesis against MPTP/MPP(+)...
Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenylTsugunobu Andoh
School of Pharmacy, Taipei Medical University, 250 Wu-Xing Street, Taipei 110, Taiwan
Mol Pharmacol 68:1408-14. 2005..In conclusion, without modifying MAO-B activity, selegiline augments the gene induction of Trx, leading to elevated expression of antioxidative MnSOD and antiapoptotic Bcl-2 proteins for protecting against MPP+-induced neurotoxicity...
Contradictory effects of sodium nitroprusside and S-nitroso-N-acetylpenicillamine on oxidative stress in brain dopamine neurons in vivoPekka Rauhala
Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland
Ann N Y Acad Sci 962:60-72. 2002..g., GSNO and SNAP) can scavenge reactive oxygen species and activate the heme moiety of guanylyl cyclase, resulting in protection of brain dopamine neurons through both antioxidative and antiapoptotic mechanisms...
Nitric oxide: an antioxidant and neuroprotectorKochupurackal P Mohanakumar
Laboratory of Experimental and Clinical Neuroscience, Indian Institute of Chemical Biology, Calcutta, India
Ann N Y Acad Sci 962:389-401. 2002..This evidence suggests that NO renders protection against MPTP-induced OH-mediated nigrostriatal lesions, acting as an antioxidant...
17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotectionSang Y Lee
Department of Neuroscience and Anatomy, Penn State University College of Medicine, M.S. Hershey Medical Center, Hershey, Pennsylvania, USA
FASEB J 17:947-8. 2003..We conclude that cGMP-dependent expression of Trx--the redox protein with potent antioxidative and antiapoptotic properties--may play a pivotal role in estrogen-induced neuroprotection...
Neuroprotective properties of nitric oxide and S-nitrosoglutathionePekka Rauhala
Institute of Biomedicine, Pharmacology, Biomedicum Helsinki, P O Box 63, University of Helsinki 00014, Helsinki, Finland
Toxicol Appl Pharmacol 207:91-5. 2005....
S-nitrosoglutathione (GSNO) mediates brain response to hypoxiaChuang C Chiueh
Pediatr Res 51:414. 2002
Angeli's salt induces neurotoxicity in dopaminergic neurons in vivo and in vitroAntiii J Väänänen
Institute of Biomedicine Pharmacology, P O Box 63, University of Helsinki, 00014 Helsinki, Finland
Free Radic Res 37:381-9. 2003....
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response frameworkEdward J Calabrese
School of Public Health, Morrill I, N344, University of Massachusetts, Amherst, MA 01003, USA
Toxicol Appl Pharmacol 222:122-8. 2007....
