Po Min Chen

Summary

Affiliation: Taipei Veterans General Hospital
Country: Taiwan

Publications

  1. ncbi request reprint Fulminant hepatitis is significantly increased in hepatitis B carriers after allogeneic bone marrow transplantation
    P M Chen
    Department of Medicine, Veterans General Hospital, Taipei, Taiwan, Republic of China
    Transplantation 67:1425-33. 1999
  2. ncbi request reprint Decreased FHIT protein expression correlates with a worse prognosis in patients with diffuse large B-cell lymphoma
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201 Shih Pai Road, Section 2, Taipei 112, Taiwan, R O C
    Oncol Rep 11:349-56. 2004
  3. ncbi request reprint Low incidence of BCL-6 gene alterations for diffuse large B-cell lymphomas in Taiwan Chinese
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Section 2, Shih Pai Road, Taipei 112, Taiwan, Republic of China
    Cancer 94:2635-44. 2002
  4. doi request reprint Patients with diffuse large B cell lymphoma in partial response or stable disease after first-line R-CHOP: the prognostic value of the absolute lymphocyte count and impact of autologous stem cell transplantation
    Man Hsin Hung
    Division of Haematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan 11217, Republic of China
    Ann Hematol 91:1907-15. 2012
  5. doi request reprint High prevalence of occult hepatitis B virus infection in patients with B cell non-Hodgkin's lymphoma
    Ming Huang Chen
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Ann Hematol 87:475-80. 2008
  6. doi request reprint ERCC1 codon 118 C→T polymorphism associated with ERCC1 expression and outcome of FOLFOX-4 treatment in Asian patients with metastatic colorectal carcinoma
    Peter Mu Hsin Chang
    School of Medicine, National Yang Ming University School of Medicine, No 155 Sec 2 Linong Street, Taipei, Taiwan
    Cancer Sci 100:278-83. 2009
  7. doi request reprint Comparison of prognostic models for patients with diffuse large B-cell lymphoma in the rituximab era
    Yu Chung Huang
    Division of Hematology and Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan, Taiwan, Republic of China
    Ann Hematol 92:1513-20. 2013
  8. ncbi request reprint Increased NBS1 expression is a marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation
    Muh Hwa Yang
    Institute of Clinical Medicine, National Yang Ming University, No 155 Li Nong Street Sec 2, Peitou, Taipei 112, Taiwan
    Clin Cancer Res 12:507-15. 2006
  9. doi request reprint Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer
    Peter Mu Hsin Chang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    J Chin Med Assoc 71:336-41. 2008
  10. doi request reprint Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma
    Yen Chung Chen
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer Sci 101:530-5. 2010

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Fulminant hepatitis is significantly increased in hepatitis B carriers after allogeneic bone marrow transplantation
    P M Chen
    Department of Medicine, Veterans General Hospital, Taipei, Taiwan, Republic of China
    Transplantation 67:1425-33. 1999
    ....
  2. ncbi request reprint Decreased FHIT protein expression correlates with a worse prognosis in patients with diffuse large B-cell lymphoma
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201 Shih Pai Road, Section 2, Taipei 112, Taiwan, R O C
    Oncol Rep 11:349-56. 2004
    ..Our result indicates that abnormal FHIT mRNA expression is noted frequently in NHL cell lines and a certain proportion of NHL patients, and decreased FHIT protein expression indicates a significantly worse prognosis in DLBCLs...
  3. ncbi request reprint Low incidence of BCL-6 gene alterations for diffuse large B-cell lymphomas in Taiwan Chinese
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Section 2, Shih Pai Road, Taipei 112, Taiwan, Republic of China
    Cancer 94:2635-44. 2002
    ....
  4. doi request reprint Patients with diffuse large B cell lymphoma in partial response or stable disease after first-line R-CHOP: the prognostic value of the absolute lymphocyte count and impact of autologous stem cell transplantation
    Man Hsin Hung
    Division of Haematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan 11217, Republic of China
    Ann Hematol 91:1907-15. 2012
    ..The results suggest intensive chemotherapy plus ASCT may provide modest disease control in patients with DLBCL who achieve PR or SD to first-line R-CHOP, particularly in those with a higher IPI score and/or low ALC at diagnosis...
  5. doi request reprint High prevalence of occult hepatitis B virus infection in patients with B cell non-Hodgkin's lymphoma
    Ming Huang Chen
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Ann Hematol 87:475-80. 2008
    ..B cell NHL patients, even HBsAg-negative B cell NHL patients, but not T cell NHL patients, have a higher incidence of HBV infection than patients with solid tumors. Our findings support the etiologic role of HBV infection in B cell NHL...
  6. doi request reprint ERCC1 codon 118 C→T polymorphism associated with ERCC1 expression and outcome of FOLFOX-4 treatment in Asian patients with metastatic colorectal carcinoma
    Peter Mu Hsin Chang
    School of Medicine, National Yang Ming University School of Medicine, No 155 Sec 2 Linong Street, Taipei, Taiwan
    Cancer Sci 100:278-83. 2009
    ..02). These data suggest that Asian populations have a significantly higher prevalence of the C/C genotype in ERCC1 codon 118, which could be a key determinant for good responses to oxaliplatin-based treatment and favorable outcomes...
  7. doi request reprint Comparison of prognostic models for patients with diffuse large B-cell lymphoma in the rituximab era
    Yu Chung Huang
    Division of Hematology and Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan, Taiwan, Republic of China
    Ann Hematol 92:1513-20. 2013
    ..Development of a new score is needed for a better risk stratification in the rituximab era and would be helpful in the design of future clinical trials. The proposed three-factor model should be validated in large-scale studies...
  8. ncbi request reprint Increased NBS1 expression is a marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation
    Muh Hwa Yang
    Institute of Clinical Medicine, National Yang Ming University, No 155 Li Nong Street Sec 2, Peitou, Taipei 112, Taiwan
    Clin Cancer Res 12:507-15. 2006
    ..We showed previously that c-MYC directly activates the expression of the DNA double-strand break repair gene NBS1, and NBS1 overexpression contributes to transformation. Here, we investigate the role of NBS1 overexpression in HNSCC...
  9. doi request reprint Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer
    Peter Mu Hsin Chang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    J Chin Med Assoc 71:336-41. 2008
    ..To determine the efficacy and safety profile of the combination of cisplatin and 5-fluorouracil modulated both by methotrexate and leucovorin in metastatic/recurrent squamous cell carcinoma of the head and neck...
  10. doi request reprint Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma
    Yen Chung Chen
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer Sci 101:530-5. 2010
    ..I105V polymorphism in GSTP1, by reducing its enzymatic activity and consequential detoxification to oxaliplatin, could be a key determinant for a better outcome, but more neurotoxicity, to FOLFOX-4 treatment...
  11. ncbi request reprint High prevalence of SV40 infection in patients with nodal non-Hodgkin's lymphoma but not acute leukemia independent of contaminated polio vaccines in Taiwan
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veteran General Hospital, Taipei, Taiwan, Republic of China
    Cancer Invest 24:223-8. 2006
    ..0001). Prospective studies are needed to determine the prevalence of SV40 infections in our and other human populations and to explore the means of transmission of the virus...
  12. ncbi request reprint Copy number changes of target genes in chromosome 3q25.3-qter of esophageal squamous cell carcinoma: TP63 is amplified in early carcinogenesis but down-regulated as disease progressed
    Chueh Chuan Yen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, China
    World J Gastroenterol 11:1267-72. 2005
    ..However, amplification patterns of these genes in EC-SCC have never been reported. The possible association of copy number changes of these genes with pathologic characteristics is still not clear...
  13. ncbi request reprint Tumor marker CEA in monitoring of response to tegafur-uracil and folinic acid in patients with metastatic colorectal cancer
    Wei Shu Wang
    Department of Medicine, Division of Medical Oncology, Veterans General Hospital, Taipei, Taiwan
    Hepatogastroenterology 49:388-92. 2002
    ..This study was carried out in an effort to evaluate the correlation between serial change on imaging and on CEA (carcinoembryonic antigen) levels for assessing chemotherapeutic response of patients with metastatic colorectal cancer...
  14. ncbi request reprint Outcome of colorectal carcinoma in patients under 40 years of age
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, 201 Sec 2 Shi Pai Road, Shi Pai, Taipei 112, Taiwan
    J Gastroenterol Hepatol 20:900-5. 2005
    ..Colorectal carcinoma in patients under 40 years of age usually has a poor prognosis. Controversies still exist regarding the features and the prognosis of colorectal cancer in young patients...
  15. ncbi request reprint Higher fungal infection rate in elderly patients (more than 80 years old) suffering from diffuse large B cell lymphoma and treated with rituximab plus CHOP
    Peng Chan Lin
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Ann Hematol 86:95-100. 2007
    ..Adding rituximab to the standard CHOP regimen in elderly DLBCL patients might increase the incidence of fungal infection especially in those older than 80 years old...
  16. doi request reprint PML protein as a prognostic molecular marker for patients with esophageal squamous cell carcinomas receiving primary surgery
    Chueh Chuan Yen
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Surg Oncol 103:761-7. 2011
    ..We evaluated the clinicopathological associations and prognostic implications of promyelocytic leukemia gene (PML) expressions in patients with esophageal squamous cell carcinomas (ESCC) receiving primary surgery...
  17. ncbi request reprint CA19-9 as the most significant prognostic indicator of metastatic colorectal cancer
    Wei Shu Wang
    Division of Medical Oncology, Department of Medicine, Veterans General Hospital Taipei, Taipei 11217, Taiwan, ROC
    Hepatogastroenterology 49:160-4. 2002
    ..However, these reports are contradictory and lack definite conclusions. This study was carried out in an effort to evaluate the prognostic significance of serum CA19-9 levels in patients with metastatic colorectal cancer in Taiwan...
  18. ncbi request reprint Extended lamivudine therapy against hepatitis B virus infection in hematopoietic stem cell transplant recipients
    Liang Tsai Hsiao
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Biol Blood Marrow Transplant 12:84-94. 2006
    ..016-0.908; P = .040). In conclusion, extended lamivudine therapy is safe and effective for the prevention of HBV reactivation in an HSCT setting and significantly decreases reactivation hepatitis after transplantation...
  19. doi request reprint Effect of allogeneic hematopoietic stem cell transplantation from matched siblings or unrelated donors during the first complete remission in patients with cytogenetically normal acute myeloid leukemia
    Yao Yu Hsieh
    Division of Haematology and Oncology, Department of Medicine, Taipei Veterans General Hospital Taipei, Taipei, Taiwan
    Eur J Haematol 86:237-45. 2011
    ..We suggest that future studies employ molecular classification of AML to better define the benefits of HSCT during CR1 in patients with CN-AML...
  20. ncbi request reprint Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients
    Wei Shu Wang
    National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Oncologist 12:312-9. 2007
    ..8%), or survival. These data indi-cate that oral glutamine significantly reduces the incidence and severity of peripheral neuropathy of MCRC patients receiving oxaliplatin without affecting response to chemotherapy and survival...
  21. ncbi request reprint N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data
    Peng Chan Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taiwan, Republic of China
    Support Care Cancer 14:484-7. 2006
    ..We concluded that oral N-acetylcysteine reduces the incidence of oxaliplatin-induced neuropathy in colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy...
  22. ncbi request reprint Unusually high incidence of upper urinary tract urothelial carcinoma in Taiwan
    Muh Hwa Yang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Urology 59:681-7. 2002
    ....
  23. ncbi request reprint Oxaliplatin added to simplified bimonthly low-dose leucovorin and 5-FU for pretreated advanced colorectal cancer is effective and not affected by different previous 5-FU regimens
    Ruey Kuen Hsieh
    Division of Hematology Oncology, Mackay Memorial Hospital, Taipei, Taiwan
    Cancer Invest 22:171-9. 2004
    ..With necessary caution, this regimen was effective for 5-FU-pretreated CRC, regardless of ethnic differences, and it had the advantage of LV being administrated at a low dose in a simplified way...
  24. ncbi request reprint Genotypic analysis of esophageal squamous cell carcinoma by molecular cytogenetics and real-time quantitative polymerase chain reaction
    Chueh Chuan Yen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Int J Oncol 23:871-81. 2003
    ..001). Combination of CGH, SKY and FISH could reveal detailed chromosomal changes associated with esophageal cancer cells, and Q-PCR could assess the change of the candidate genes in clinical samples in a high throughput way...
  25. ncbi request reprint Irinotecan (CPT11) plus high-dose 5-fluorouracil (5-FU) and leucovorin (LV) as salvage therapy for metastatic colorectal cancer (MCRC) after failed oxaliplatin plus 5-FU and LV: a pilot study in Taiwan
    Cheng Jeng Tai
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, 201 Shih Pai Road, Sec 2, Pei Tou, 112 Taipei, Taiwan
    Jpn J Clin Oncol 33:136-40. 2003
    ..We conducted this pilot study to evaluate the efficacy and tolerance of combination treatment with irinotecan and 5-fluorouracil (5-FU) for patients in whom combination treatment with oxaliplatin with 5-FU + leucovorin has failed...
  26. doi request reprint A nation-wide analysis of venous thromboembolism in 497,180 cancer patients with the development and validation of a risk-stratification scoring system
    Yuan Bin Yu
    Institutes of Physiology, School of Medicine, National Yang Ming University, Taipei, Taiwan
    Thromb Haemost 108:225-35. 2012
    ..In conclusion, VTE is a distinct burden for cancer patients in Taiwan. The risk scoring system could prove helpful in decision-making concerning thromboprophylaxis in cancer patients...
  27. ncbi request reprint Severe anaphylactic reactions in patients receiving oxaliplatin therapy: a rare but potentially fatal complication
    Ming Yang Lee
    Division of Hemato Oncology, Department of Internal Medicine, Chia Yi Christian Hospital, Chia Yi, Taiwan, Republic of China
    Support Care Cancer 15:89-93. 2007
    ..However, hypersensitivity reaction of oxaliplatin, especially severe anaphylactic reactions (SAR), was less often reported...
  28. doi request reprint Absolute lymphocyte count predicts response to rituximab-containing salvage treatment for relapsed/refractory B-cell non-Hodgkin's lymphoma with prior rituximab exposure
    Man Hsin Hung
    Division of Haematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 76:195-200. 2013
    ....
  29. ncbi request reprint Pegylated liposomal doxorubicin-based combination chemotherapy as salvage treatment in patients with advanced hepatocellular carcinoma
    Say Bee Poh
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, and the National Yang Ming University Taipei, Taiwan
    Am J Clin Oncol 28:540-6. 2005
    ..The authors evaluate its activity in combination with capecitabine or gemcitabine as salvage therapy in these patients...
  30. ncbi request reprint Epidermal growth factor receptor R497K polymorphism is a favorable prognostic factor for patients with colorectal carcinoma
    Wei Shu Wang
    National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Clin Cancer Res 13:3597-604. 2007
    ..Because the activation of EGFR results in an unfavorable prognosis of patients with colorectal carcinoma, a pilot study was conducted to assess the influence of this polymorphism on colorectal carcinoma patients...
  31. ncbi request reprint Sequential therapy with capecitabine followed by vinorelbine/cisplatin in patients with anthracycline/taxane-refractory metastatic breast cancer
    Peng Chan Lin
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    J Chin Med Assoc 69:304-9. 2006
    ..In this study, we analyzed the efficacy and toxicity of sequential therapy with capecitabine followed by biweekly vinorelbine plus cisplatin in 37 patients with anthracycline and taxane-refractory MBC in Taipei Veterans General Hospital...
  32. ncbi request reprint Expression of a soluble decoy receptor 3 in patients with diffuse large B-cell lymphoma predicts clinical outcome
    Peter Mu Hsin Chang
    Faculty of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, R O C
    Int J Oncol 33:549-54. 2008
    ..We suggest that overexpression of DcR3 is associated with a worse prognosis in DLBCL and the possible mechanism may act through the increase of chemo-resistance of lymphoma cells...
  33. ncbi request reprint A dose-escalating pilot study of sterically stabilized, pegylated liposomal doxorubicin (Lipo-Dox) in patients with metastatic breast cancer
    Ta Chung Chao
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University, School of Medicine, Taipei, Taiwan, ROC
    Cancer Invest 21:837-47. 2003
    ....
  34. ncbi request reprint EIA versus RIA in detecting carcinoembryonic antigen level of patients with metastatic colorectal cancer
    Wei Shu Wang
    Division of Medical Oncology, Department of Medicine, Veterans General Hospital, Taipei, Taiwan
    Hepatogastroenterology 51:136-41. 2004
    ..Because EIA has the advantage of avoiding the use of radioisotopes, the potential of using EIA instead of RIA in detecting CEA of patients with colorectal cancer is of interest to us...
  35. ncbi request reprint Pulmonary nocardiosis in a patient with CML relapse undergoing imatinib therapy after bone marrow transplantation
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Shi Pai, Taiwan
    Ann Hematol 83:444-6. 2004
    ..Our case indicated that pulmonary nocardiosis could occur in patients with GVHD undergoing imatinib and corticosteroid therapy and might be treated by single-agent TMP/SMX...
  36. ncbi request reprint Detection of reactivation and genetic mutations of the hepatitis B virus in patients with chronic hepatitis B infections receiving hematopoietic stem cell transplantation
    Po Min Chen
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital Department of Medicine, Taipei, Republic of China
    Transplantation 74:182-8. 2002
    ..This study elucidates the profiles for hepatitis B virus (HBV) reactivation and genetic mutation of the core promoter and precore regions for HBV-carriers receiving hematopoietic stem cell transplantation (HSCT)...
  37. pmc Chronic hepatitis virus infection in patients with multiple myeloma: clinical characteristics and outcomes
    Chung Jen Teng
    National Yang Ming University Hospital, Department of Medicine, Division of Hematology and Oncology, Yilan, Taiwan, Republic of China
    Clinics (Sao Paulo) 66:2055-61. 2011
    ..For patients with multiple myeloma, the impact of preexisting hepatitis virus infection is unclear. The aim of this study is to explore the characteristics and outcomes of myeloma patients with chronic hepatitis virus infection...
  38. doi request reprint Low absolute lymphocyte count and addition of rituximab confer high risk for interstitial pneumonia in patients with diffuse large B-cell lymphoma
    Yu Chung Huang
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201 Sec 2 Shipai Road, Taipei, Taiwan, Republic of China
    Ann Hematol 90:1145-51. 2011
    ..In conclusion, the incidence of IP is increased in patients with DLBCL receiving rituximab-containing chemotherapy. Specific subgroups with lymphopenia at diagnosis may justify close scrutiny to detect pulmonary complications...
  39. doi request reprint Leukocytosis in polycythemia vera and splenomegaly in essential thrombocythemia are independent risk factors for hemorrhage
    Yi Sheng Chou
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan National Yang Ming University School of Medicine, Taipei, Taiwan
    Eur J Haematol 90:228-36. 2013
    ..Long-term outcomes are favorable for patients with polycythemia vera (PV) and for patients with essential thrombocythemia (ET). However, hemorrhage is a significant cause of morbidity and mortality in those patients...
  40. doi request reprint International Staging System predicts prognosis of Chinese patients with multiple myeloma across different calendar periods with application of novel agents
    Sheng Hsiang Yang
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan
    Ann Hematol 91:93-102. 2012
    ..This is the first study to show the applicability of ISS for Chinese patients with MM, especially for those who had received thalidomide...
  41. doi request reprint Cetuximab-based therapy in recurrent/metastatic head and neck squamous cell carcinoma: experience from an area in which betel nut chewing is popular
    Peter Mu Hsin Chang
    Division of Hematology Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 73:292-9. 2010
    ..This study was undertaken to evaluate the efficacy and safety of cetuximab-based therapy in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) in an area in which betel nut chewing is popular...
  42. doi request reprint Direct regulation of TWIST by HIF-1alpha promotes metastasis
    Muh Hwa Yang
    Institutes of Biochemistry and Molecular Biology, National Yang Ming University, No 155, Sec 2, Li Niong Street, Peitou, Taipei 112, Taiwan
    Nat Cell Biol 10:295-305. 2008
    ..These results provide evidence of a key signalling pathway involving HIF-1alpha and TWIST that promotes metastasis in response to intratumoural hypoxia...
  43. ncbi request reprint Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells
    Wei Shu Wang
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei 112, Taiwan, Republic of China
    Oncogene 22:3297-306. 2003
    ....
  44. ncbi request reprint Non-Hodgkin lymphoma in elderly patients: experience at Taipei Veterans General Hospital
    Li Yuan Bai
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Cancer 98:1188-95. 2003
    ..The annual incidence of non-Hodgkin lymphoma (NHL) has increased over the past two decades in all age groups, including the elderly. Establishing guidelines for proper care for this segment of the population requires further information...
  45. doi request reprint UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma
    Chun Yu Liu
    National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    Cancer 112:1932-40. 2008
    ..This study was conducted to assess the influence of this polymorphism on the efficacy and toxicity of irinotecan treatment in Chinese patients with metastatic colorectal carcinoma (CRC)...
  46. ncbi request reprint Chryseobacterium indologenes bacteremia in a bone marrow transplant recipient with chronic graft-versus-host disease
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan
    Scand J Infect Dis 35:882-3. 2003
    ..Our case indicates that C. indologenes infection can occur in patients with GVHD after allogeneic BMT and might be treated with a single agent, piperacillin/tazobactam without the removal of intravascular catheter...
  47. ncbi request reprint Prognostic significance of clonal diversity of immunoglobulin gene rearrangements in patients with diffuse large B-cell lymphoma
    Muh Hwa Yang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201 Sec 2 Shih Pai Rd, Taipei 112, Taiwan
    Oncol Rep 13:503-8. 2005
    ..It is also a factor of poor prognosis in DLBCL, especially for high-intermediate risk category...
  48. doi request reprint Large pericardial effusion as a life-threatening complication after hematopoietic stem cell transplantation-association with chronic GVHD in late-onset adult patients
    Yao Chung Liu
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, 112, Taiwan, Republic of China
    Ann Hematol 91:1953-8. 2012
    ..The etiology is probably related to chronic GVHD in cases of late onset. Emergent pericardiocentesis and enhanced immunosuppression can effectively control this life-threatening complication...
  49. doi request reprint Pre-existing diabetes mellitus in patients with multiple myeloma
    Yi Sheng Chou
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Eur J Haematol 89:320-7. 2012
    ..However, the impact of type 2 diabetes on the survival of patients with MM has not been studied...
  50. doi request reprint Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy
    Yao Yu Hsieh
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer Sci 103:791-6. 2012
    ....
  51. doi request reprint Chronic kidney disease stage 5 as the prognostic complement of International Staging System for multiple myeloma
    Liang Tsai Hsiao
    Division of Hematology and Oncology, Department of Medicine, Taipei, Taiwan
    Eur J Haematol 88:159-66. 2012
    ..However, the prognostic impact of eGFR(MDRD) at diagnosis of MM is not well studied, particularly its use in conjunction with the International Staging System (ISS)...
  52. ncbi request reprint Down-regulation of Notch-1 expression decreases PU.1-mediated myeloid differentiation signaling in acute myeloid leukemia
    Po Min Chen
    Division of Hematology Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan R O C
    Int J Oncol 32:1335-41. 2008
    ..These results suggest that down-regulation of Notch-1 expression decreases PU.1/MCSFR expression and disrupts the Notch-1/PU.1 complex, which may impede the PU.1-mediated myeloid signaling and contribute to the leukemogenesis of AML...
  53. doi request reprint Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study
    Peter Mu Hsin Chang
    Department of Medicine, Division of Hematology Oncology, Taipei Veterans General Hospital, Taipei, Taiwan
    Cancer Chemother Pharmacol 63:9-17. 2008
    ....
  54. doi request reprint Diffusion capacity predicts long-term survival after allogeneic bone marrow transplantation for acute lymphoblastic leukemia
    Peter Mu Hsin Chang
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 71:234-40. 2008
    ..The aim of this study was to evaluate changes in pulmonary function measures as predictors of outcome in acute lymphoblastic leukemia (ALL) patients after myeloablative allogeneic bone marrow transplantation (BMT)...
  55. ncbi request reprint Comparison of myeloablative and nonmyeloablative hematopoietic stem cell transplantation for treatment of chronic myeloid leukemia
    Ming Huang Chen
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Int J Hematol 86:275-81. 2007
    ..Further larger-scale randomized clinical trials are warranted to clarify the efficacy of this treatment regimen...
  56. ncbi request reprint Plasma von Willebrand factor level as a prognostic indicator of patients with metastatic colorectal carcinoma
    Wei Shu Wang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan, China
    World J Gastroenterol 11:2166-70. 2005
    ..To evaluate the correlations of plasma von Willebrand factor (vWF) level with the distant metastasis and prognosis of patients with colorectal cancer...
  57. ncbi request reprint Stevens-Johnson syndrome after treatment with STI571: a case report
    Liang Tsai Hsiao
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei 112, Taiwan
    Br J Haematol 117:620-2. 2002
    ..This report may serve to remind the clinician about the possible severe cutaneous side-effects of STI571 before instituting more extensive clinical application of this agent in the future...
  58. ncbi request reprint Rituximab therapy increased post-transplant cytomegalovirus complications in Non-Hodgkin's lymphoma patients receiving autologous hematopoietic stem cell transplantation
    Ming Yang Lee
    Division of Hemato Oncology, Department of Medicine, Chia Yi Christian Hospital, Chia Yi, Taiwan, ROC
    Ann Hematol 87:285-9. 2008
    ..7% vs 0%, p = 0.131, Fisher exact test, two-sided). The NHL patients receiving rituximab therapy had higher risk to develop CMV infectious complications after autologous HSCT...
  59. doi request reprint Prolonged facial edema is an indicator of poor prognosis in patients with head and neck squamous cell carcinoma
    Ming Huang Chen
    School of Medicine, National Yang Ming University, Taipei, Taiwan
    Support Care Cancer 18:1313-9. 2010
    ..Facial edema sometimes is observed in patients with head and neck squamous cell carcinoma (HNSCC), but its prevalence and association with other factors is unclear...
  60. doi request reprint Promising overall survival of patients with recurrent/metastatic squamous cell carcinoma of head and neck receiving gemcitabine plus cisplatin treatment: report of a multi-center phase II study
    Muh Hwa Yang
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
    Cancer Chemother Pharmacol 65:259-65. 2010
    ..The efficacy and safety of gemcitabine in combination with cisplatin (GC) as the first-line treatment in patients with recurrent/metastatic (R/M) squamous cell carcinoma of head and neck (SCCHN) was examined...
  61. ncbi request reprint All-trans retinoid acid increases Notch1 transcript expression in acute promyelocytic leukemia
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University, School of Medicine, Taipei, Taiwan
    Adv Ther 20:337-43. 2003
    ..As Notch1 gene is involved in the differentiation and leukemogenesis in lymphoid neoplasm, observations suggest that Notch1 is involved in ATRA-modulated differentiation process in APL...
  62. ncbi request reprint High serum hepatocyte growth factor level in patients with non-Hodgkin's lymphoma
    Liang Tsai Hsiao
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taiwan
    Eur J Haematol 70:282-9. 2003
    ..The pathogenic role of HGF in NHL patients was further highlighted by a modest expression of HGF in most of the diffuse large B cell lymphoma...
  63. ncbi request reprint Prognostic-factors-based risk-stratification model for invasive urothelial carcinoma of the urinary bladder in Taiwan
    Muh Hwa Yang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, People s Republic of China, Taipei, Taiwan
    Urology 59:232-8; discussion 238-9. 2002
    ..The incidence of recurrent disease is significantly higher for patients with poor renal function before treatment or advanced T stage and those undergoing transurethral tumor resection instead of radical cystectomy...
  64. ncbi request reprint Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma
    Wei Shu Wang
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Oncogene 23:6666-71. 2004
    ....
  65. ncbi request reprint Intravenous busulfan as preparative regimen in pediatric patients receiving hematopoietic stem cell transplantation: the preliminary experience in Taiwan
    Ming Yang Lee
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
    J Chin Med Assoc 67:117-22. 2004
    ..In this study, we aimed to evaluate the efficacy and complications of IV busulfan in pediatric patients...
  66. ncbi request reprint Pulmonary function changes in long-term survivors of chronic myelogenous leukemia after allogeneic bone marrow transplantation: a Taiwan experience
    Tzeon Jye Chiou
    Section of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, No 201, Sec 2, Shih Pai Road, Taipei 112, Taiwan, ROC
    Cancer Invest 20:880-8. 2002
    ..The primary negative presentation with the development of oxygenation defect had no clinical significance in most patients. The influences on the impairment of pulmonary function were multifactorial...
  67. ncbi request reprint Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma
    Wei Shu Wang
    Division of Medical Oncology, Department of Medicine Division of Colorectal Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Carcinogenesis 27:1113-20. 2006
    ....
  68. ncbi request reprint An intron promotes the anti-bcr-abl activities of a retrovirally expressed ribozyme in chronic myeloid leukemia cells
    Jin Hwang Liu
    Division of Medical Oncology, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan, ROC
    Biochem Biophys Res Commun 318:764-72. 2004
    ..Noticeably, the improvement is contributed in part by subcellular co-localization...
  69. ncbi request reprint Stage IV thymic carcinoma: a study of 20 patients
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Med Sci 330:172-5. 2005
    ..This study was performed to investigate the clinical factors, tumor characteristics, treatment approach, and prognosis of patients with Stage IV thymic carcinoma (WHO type C)...
  70. ncbi request reprint A new model for predicting the timing of leukapheresis on the basis of CD34+ cell and hematopoietic progenitor cell levels
    Hao Wei Teng
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Clin Apher 22:195-203. 2007
    ..Patients with borderline marrow potential may benefit from delaying leukapheresis until the WBC level is >10,000/microl and leukapheresis extended more than 3 days...
  71. ncbi request reprint Randomized Phase II trial of thalidomide alone versus thalidomide plus interferon alpha in patients with refractory multiple myeloma
    Tzeon Jye Chiou
    Section of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer Invest 25:140-7. 2007
    ..It may be concluded that the combined regimen is not well tolerated in our patients and needed to be further evaluated in the future...
  72. doi request reprint Prognostic significance of a pretreatment hematologic profile in patients with head and neck cancer
    Ming Huang Chen
    Division of Hematology Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Cancer Res Clin Oncol 135:1783-90. 2009
    ..The purpose of this retrospective study was to test whether the pretreatment hematologic profile can predict the prognosis of patients with head and neck cancer...
  73. ncbi request reprint 2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer
    Heng Liang Lin
    Department of Medical Research and Education, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan
    Int J Cancer 121:2547-55. 2007
    ..We conclude that the activation of PI3K/Akt pathway is involved in the late-stage progression and metastasis of gastric cancer, and attenuation of p-Akt by 2-ME suppresses metastasis...
  74. doi request reprint Clinical features and prognostic factors of angioimmunoblastic T-cell lymphoma in Taiwan: a single-institution experience
    Han Nan Lin
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Leuk Lymphoma 51:2208-14. 2010
    ..Taiwanese patients with AITL were usually elderly. Despite the prognosis being generally poor, patients with AITL should be treated with the goal of achieving CR, regardless of anthracycline- or non-anthracycline-based chemotherapy...
  75. doi request reprint Prognostic factors of Chinese patients with primary pulmonary non-Hodgkin's lymphoma: the single-institute experience in Taiwan
    Yu Hui Hu
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Ann Hematol 88:839-46. 2009
    ..The two prognostic factors provided additional information in managing these patients...
  76. ncbi request reprint Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma
    Fen Hwa Wong
    Faculty of Life Sciences and Institute of Genome Sciences, National Yang Ming University, No 155, Sec 2, Taipei 112, Taiwan, R O C
    Int J Oncol 34:117-28. 2009
    ..Our study not only reveals how novel insights can be obtained from gene expression profiling, but also highlights a group of highly interacting genes associated with metastasis in ESCC...
  77. doi request reprint Virus reactivation in high-risk non-Hodgkin's lymphoma patients after autologous CD34+ -selected peripheral blood progenitor cell transplantation
    Peng Chan Lin
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei 112, Taiwan
    Int J Hematol 87:434-9. 2008
    ..Administering prophylactic antivirus therapy and closely following patient's clinical viral complications should be considered...
  78. ncbi request reprint The prolonged activated partial thromboplastin time at diagnosis indicates less favorable prognosis in IgA myeloma
    Hao Wei Teng
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Jpn J Clin Oncol 37:609-14. 2007
    ..We aimed to assess the correlation between activated partial thromboplastin time/prothrombin time at diagnosis and overall survival in myeloma patients...
  79. doi request reprint Subcutaneous panniculitis-like T cell lymphoma: familial aggregation while different response to chemotherapy
    Jyh Pyng Gau
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, No 201, Section 2, Shih Pai Road, Taipei, Taiwan
    Int J Hematol 89:63-5. 2009
    ..Both of them had hemophagocytic syndrome preceding the full-blown manifestations of the lymphoma. However, severity of the disease and the response to chemotherapy is quite different between the two siblings...
  80. ncbi request reprint Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma
    Chueh Chuan Yen
    Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Oncol 35:775-88. 2009
    ..The study also demonstrated that CN and LOH analyses were able to detect distinct subsets of genetic abnormalities in OS...
  81. ncbi request reprint Overexpression of cyclin D1 in accelerated-phase chronic myeloid leukemia
    Jin Hwang Liu
    Division of Medical Oncology and Hematology Taipei Veterans General Hospital and National Yang Ming University School of Medicine Taipei Taiwan
    Leuk Lymphoma 45:2419-25. 2004
    ..These results suggest that the expression level of cyclin D1 RNA in bone marrow cells is predictive of the phase evolution in CML and may be helpful in treatment decision-making...
  82. ncbi request reprint Acute graft-versus-host disease of the lung with atypical presentation
    Peng Chan Lin
    Department of Medical Oncology, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    Int J Hematol 84:1. 2006
  83. ncbi request reprint Superior vena cava syndrome and hypercalcaemia in a patient with a primary mediastinal B-cell lymphoma secreting parathyroid hormone-related protein
    Liang Tsai Hsiao
    Department of Pathology, Taipei Veterans General Hospital, Taiwan
    Br J Haematol 119:1. 2002
  84. ncbi request reprint Graft-versus-T-cell non-Hodgkin's lymphoma effect
    Liang Tsai Hsiao
    Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan
    Int J Hematol 83:193. 2006
  85. ncbi request reprint Acute polymyositis after donor lymphocyte infusion
    Peng Chan Lin
    Department of Medical Oncology, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
    Eur J Haematol 74:166-8. 2005
    ..Acute polymyositis developed following DLI 22 d later. The clinical presentation of polymyositis is compatible with a manifestation of acute GVHD following DLI. It also responds to the treatment of steroid and CsA...
  86. ncbi request reprint Thalidomide for the treatment of myelodysplastic syndrome in Taiwan: results of a phase II trial
    Chih Yuan Chung
    Department of Internal Medicine, Changhua Christian Hospital, Taiwan, R O C
    Anticancer Res 32:3415-9. 2012
    ..Thalidomide inhibits angiogenesis and exerts complex immunomodulatory activities. This phase II study aimed to examine the efficacy of thalidomide in Taiwanese patients with myelodysplastic syndrome (MDS)...
  87. doi request reprint Activation of phosphoinositide 3-kinase by the NBS1 DNA repair protein through a novel activation motif
    Yen Chung Chen
    Institute of Biochemistry and Molecular Biology, National Yang Ming University, No 155, Li Nong St, Sec 2, Peitou, Taipei 112, Taiwan
    J Mol Med (Berl) 86:401-12. 2008
    ..These results demonstrate that NBS1 can function as an adaptor/activator of p110alpha PI 3-kinase through a novel activation motif, consistent with its possible role in cell transformation and tumorigenesis...
  88. doi request reprint Interaction between HSP60 and beta-catenin promotes metastasis
    Ya Ping Tsai
    Institute of Biochemistry and Molecular Biology, National Yang Ming University, Taipei, Taiwan
    Carcinogenesis 30:1049-57. 2009
    ..Coexpression of HSP60 and nuclear beta-catenin predicts a worse prognosis of metastatic head and neck cancer patients. These results implicate a novel role of HSP60 in metastasis...
  89. doi request reprint Very low prevalence of XPD K751Q polymorphism and its association with XPD expression and outcomes of FOLFOX-4 treatment in Asian patients with colorectal carcinoma
    Jiun I Lai
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Cancer Sci 100:1261-6. 2009
    ..03). These data suggest that Asian populations have a significantly lower prevalence of codon 751 Lys/Gln polymorphism in XPD, which could be a key determinant for good response to oxaliplatin-based treatment and favorable outcomes...
  90. ncbi request reprint Metastasis-induced acute pancreatitis in lung cancer
    Jen Tsun Lin
    Department of Medicine, Division of Hematology and Oncology, Changhua Christian Medical Center, Changhua, Taiwan
    Adv Ther 22:225-33. 2005
    ..These results may help to design a therapeutic approach in patients with MIAP complicated by lung cancer...
  91. ncbi request reprint Lymphoma presenting as Sister Mary Joseph's nodule sparing intra-abdominal involvement
    Ying Ih Shih
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Int J Hematol 83:194. 2006
  92. ncbi request reprint Fatal fulminant hepatitis B after withdrawal of prophylactic lamivudine in hematopoietic stem cell transplantation patients
    Peng Chan Lin
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University, School of Medicine, Taipei 112, Taiwan
    Int J Hematol 81:349-51. 2005
    ..We suggest that the duration of prophylactic use of lamivudine in chronic HBV carriers receiving HSCT be prolonged until the patient's immune system has been reconstituted...
  93. ncbi request reprint Acute pancreatitis during all-trans-retinoic acid treatment for acute promyelocytic leukemia in a patient without overt hypertriglyceridemia
    Hao Wei Teng
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec 2, Shih Pai Road, Taipei 112, Taiwan
    Jpn J Clin Oncol 35:94-6. 2005
    ....
  94. ncbi request reprint Prurigo nodularis as initial presentation of metastatic transitional cell carcinoma of the bladder
    Jen Tsun Lin
    Division of Medical Oncology, Department of Medicine and Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan
    J Urol 168:631-2. 2002
  95. ncbi request reprint Transplantation of related histocompatible marrow and peripheral blood stem cells in a patient with severe combined immunodeficiency and disseminated BCG infection
    Giun Yi Hung
    Department of Pediatrics, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    J Chin Med Assoc 66:72-5. 2003
    ..The patient finally expired because of failure to achieve a functioning immune system after BMT and septic shock...
  96. ncbi request reprint Delayed rejection after initial engraftment in non-myeloablative bone marrow transplantation
    Muh Hwa Yang
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 66:682-8. 2003
    ..The patient expired on day +151. We recommend that the suitability of NM-BMT for high-risk patients such as unrelated-donor BMT and elder recipients needs further studies to confirm...
  97. ncbi request reprint Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia
    Giun Yi Hung
    Department of Pediatrics, Taipei Veterans General Hospital, Taiwan
    Int J Hematol 82:159-61. 2005
    ..4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan...
  98. ncbi request reprint Punched-out lesions of the skull in elderly patients with inherited anemia
    Liang Tsai Hsiao
    Division of Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, No 201 Sec 2 Shi Pai Road, Taipei 11217, Taiwan
    Eur J Haematol 75:359. 2005
  99. ncbi request reprint Phase II study of oxaliplatin in combination with continuous infusion of 5-fluorouracil/leucovorin as first-line chemotherapy in patients with advanced gastric cancer
    Wei Shou Hwang
    Chi Mei Medical Center, Tainan, Taiwan
    Anticancer Drugs 19:283-8. 2008
    ..3%). Our study confirmed that the combination of oxaliplatin and continuous infusion of 5-FU/leucoverin without bolus 5-FU as first-line chemotherapy is active for patients with AGC and relatively safe with lower haematological toxicity...
  100. ncbi request reprint Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively
    Hung Liang Hsiao
    Institute of Pharmacology, College of Medicine, National Yang Ming University, Shih Pai, Taipei 11221, Taiwan, R O China
    Carcinogenesis 27:936-44. 2006
    ..Thus, advantages such as immune evasion and resistance to anticancer drug-induced apoptosis acquired by colon cancer cells through Tbeta4 overexpression might facilitate their survival during metastasis and chemotherapy...
  101. pmc Oral bioavailability of a novel paclitaxel formulation (Genetaxyl) administered with cyclosporin A in cancer patients
    Zyting Chu
    Department of Medical Research, China Medical University Hospital, Taichung, Taiwan
    Anticancer Drugs 19:275-81. 2008
    ..The corresponding median values for the apparent bioavailability of oral Genetaxyl were similar when compared with i.v. Genetaxyl, when calculated either on the basis of data for total paclitaxel (30.1%) or unbound paclitaxel (30.6%)...