Jaw Wen Chen

Summary

Affiliation: Taipei Veterans General Hospital
Country: Taiwan

Publications

  1. ncbi Prognostic impact of body mass index in patients undergoing coronary artery bypass surgery
    Shih Hsien Sung
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    Heart 97:648-54. 2011
  2. ncbi Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses
    Cheng Chung Cheng
    Institute of Microbiology and Immunology, National Yang Ming University, Taipei, Taiwan
    BMC Genomics 14:182. 2013
  3. ncbi Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways
    Chun Yao Huang
    Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 32:2405-17. 2012
  4. ncbi Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec 2, Shih Pai Road, Taipei, Taiwan 112, Republic of China
    Arterioscler Thromb Vasc Biol 24:2075-81. 2004
  5. ncbi Clinical characteristics of young-onset hypertension-implications for different genders
    Jaw Wen Chen
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Cardiovascular Research Center, 201 Shih Pai Road, Section 2, Taipei 11217, Taiwan, ROC
    Int J Cardiol 96:65-71. 2004
  6. ncbi Long-term exposure to oxidized low-density lipoprotein enhances tumor necrosis factor-alpha-stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Cardiovascular Research Center, Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China
    Free Radic Biol Med 40:817-26. 2006
  7. ncbi Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China
    Arterioscler Thromb Vasc Biol 23:1559-66. 2003
  8. ncbi Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X
    Jaw Wen Chen
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, and Cardiovascular Research Center, National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Cardiol 90:974-82. 2002
  9. ncbi Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways
    Shing Jong Lin
    Institute of Clinical Medicine, Cardiovascular Research Center, National Yang Ming University, Taiwan, Republic of China
    Arterioscler Thromb Vasc Biol 25:334-40. 2005
  10. ncbi Lipoprotein lipase gene is linked and associated with hypertension in Taiwan young-onset hypertension genetic study
    Pei Chen
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan
    J Biomed Sci 12:651-8. 2005

Collaborators

Detail Information

Publications111 found, 100 shown here

  1. ncbi Prognostic impact of body mass index in patients undergoing coronary artery bypass surgery
    Shih Hsien Sung
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    Heart 97:648-54. 2011
    ..Coronary artery bypass grafting (CABG) surgery is usually the treatment of choice for patients with complex CAD...
  2. ncbi Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses
    Cheng Chung Cheng
    Institute of Microbiology and Immunology, National Yang Ming University, Taipei, Taiwan
    BMC Genomics 14:182. 2013
    ..EPCs are rare and therefore optimizing isolation and culture is required before they can be applied as part of clinical therapies...
  3. ncbi Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways
    Chun Yao Huang
    Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 32:2405-17. 2012
    ..This study aimed to investigate the concentration-related effects of HDL on in vitro and in vivo functions of human endothelial progenitor cells (EPCs) and related angiogenesis...
  4. ncbi Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec 2, Shih Pai Road, Taipei, Taiwan 112, Republic of China
    Arterioscler Thromb Vasc Biol 24:2075-81. 2004
    ....
  5. ncbi Clinical characteristics of young-onset hypertension-implications for different genders
    Jaw Wen Chen
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Cardiovascular Research Center, 201 Shih Pai Road, Section 2, Taipei 11217, Taiwan, ROC
    Int J Cardiol 96:65-71. 2004
    ..Hypertension may develop early, before the age of 40 years, in both genders, so-called young-onset hypertension. The clinical characteristics of young-onset hypertension have not been well defined...
  6. ncbi Long-term exposure to oxidized low-density lipoprotein enhances tumor necrosis factor-alpha-stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Cardiovascular Research Center, Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China
    Free Radic Biol Med 40:817-26. 2006
    ..The findings suggest the pivotal role of oxidized LDL-induced oxidative stress in monocyte activation during atherogenesis...
  7. ncbi Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells
    Jaw Wen Chen
    National Yang Ming University School of Medicine, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China
    Arterioscler Thromb Vasc Biol 23:1559-66. 2003
    ....
  8. ncbi Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X
    Jaw Wen Chen
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, and Cardiovascular Research Center, National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Cardiol 90:974-82. 2002
    ..This may be related to the improvement of endothelial NO bioavailability with the reduction of plasma ADMA levels...
  9. ncbi Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways
    Shing Jong Lin
    Institute of Clinical Medicine, Cardiovascular Research Center, National Yang Ming University, Taiwan, Republic of China
    Arterioscler Thromb Vasc Biol 25:334-40. 2005
    ..We tried to study possible effects of Cu/Zn superoxide dismutase (SOD) on adhesion molecule expression and its underlying mechanism in the prevention and treatment of cardiovascular disorders...
  10. ncbi Lipoprotein lipase gene is linked and associated with hypertension in Taiwan young-onset hypertension genetic study
    Pei Chen
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan
    J Biomed Sci 12:651-8. 2005
    ..02). We conclude that LPL variants may play a causal role in the development of hypertension in Taiwan Han Chinese. The moderate association with SNP haplotype suggests that other regulatory LPL variant may exist...
  11. ncbi Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability
    Po Hsun Huang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 30:869-77. 2010
    ..This study tested the hypothesis that intake of RW may promote the circulating endothelial progenitor cell (EPC) level and function through enhancement of nitric oxide bioavailability...
  12. ncbi Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract
    Jia Shiong Chen
    Institute of Pharmacology, National Yang Ming University School of Medicine, Taipei, Taiwan, ROC
    Atherosclerosis 214:301-9. 2011
    ..GBE was recently suggested as a heme oxygenase (HO)-1 inducer. The role of HO-1 in anti-atherogenesis and related vascular protective effects of GBE awaited further clarification...
  13. ncbi Deletion of FHL2 gene impaired ischemia-induced blood flow recovery by modulating circulating proangiogenic cells
    Po Hsun Huang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 33:709-17. 2013
    ....
  14. ncbi Far infra-red therapy promotes ischemia-induced angiogenesis in diabetic mice and restores high glucose-suppressed endothelial progenitor cell functions
    Po Hsun Huang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Cardiovasc Diabetol 11:99. 2012
    ..We hypothesized that IFR radiation can restore blood flow recovery in ischemic hindlimb in diabetic mice by enhancement of EPCs functions and homing process...
  15. ncbi Globular adiponectin improves high glucose-suppressed endothelial progenitor cell function through endothelial nitric oxide synthase dependent mechanisms
    Po Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Mol Cell Cardiol 51:109-19. 2011
    ..These beneficial effects may provide some novel rational to the vascular protective properties of adiponectin...
  16. ncbi Moderate intake of red wine improves ischemia-induced neovascularization in diabetic mice--roles of endothelial progenitor cells and nitric oxide
    Po Hsun Huang
    Division of Cardiology, Department of Medical Research and Education, Taipei Veterans General Hospital, Institute of Clinical Medicine, Cardiovascular Research Center, National Yang Ming University, Taipei, Taiwan
    Atherosclerosis 212:426-35. 2010
    ..We investigated whether moderate red wine consumption can enhance blood flow recovery in response to tissue ischemia by enhancement of EPC functions in diabetic mice...
  17. ncbi Ginkgo biloba extract reduces high-glucose-induced endothelial adhesion by inhibiting the redox-dependent interleukin-6 pathways
    Jia Shiong Chen
    Institute of Pharmacology, National Yang Ming University, Taipei, Taiwan, Republic of China
    Cardiovasc Diabetol 11:49. 2012
    ..This study aimed to elucidate the detailed mechanisms of high-glucose-induced endothelial inflammation, and to investigate the potential effects of Ginkgo biloba extract (GBE), an antioxidant herbal medicine, on such inflammation...
  18. ncbi Combined use of endothelial function assessed by brachial ultrasound and high-sensitive C-reactive protein in predicting cardiovascular events
    Po Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Clin Cardiol 30:135-40. 2007
    ..Endothelial function plays a key role in determining the clinical manifestations of atherosclerotic lesions. Elevated high-sensitive C-reactive protein (hsCRP) relates to long-term prognosis of cardiovascular disease...
  19. ncbi The association of tooth scaling and decreased cardiovascular disease: a nationwide population-based study
    Zu Yin Chen
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Am J Med 125:568-75. 2012
    ..The aim of this study is to investigate the association between tooth scaling and the risk of cardiovascular events by using a nationwide, population-based study and a prospective cohort design...
  20. ncbi Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways
    Feng Yen Lin
    Graduate Institute of Medical Sciences, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 26:2630-7. 2006
    ..This study was conducted to investigate the mechanisms involved in lipopolysaccharide (LPS)-induced TLR4 expression in VSMCs...
  21. ncbi Vascular endothelial function and circulating endothelial progenitor cells in patients with cardiac syndrome X
    Po Hsun Huang
    Institute of Clinicial Medicine and corrected Cardiovascular Research Center, National Yang Ming University, Taipei, Taiwan
    Heart 93:1064-70. 2007
    ..Recent insights suggest that the injured endothelial monolayer is regenerated by circulating bone marrow-derived endothelial progenitor cells (EPCs)...
  22. ncbi Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study
    Hsin Chou Yang
    Institute of Statistical Science, Academia Sinica, Taipei, Taiwan
    PLoS ONE 7:e32907. 2012
    ..Identification of these genes enriches the collection of hypertension susceptibility genes, thereby shedding light on the etiology of hypertension in Han Chinese populations...
  23. ncbi High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms
    Yung Hsiang Chen
    School of Medicine, National Yang Ming University, Taipei City, Taiwan
    Diabetes 56:1559-68. 2007
    ..Endothelial progenitor cells (EPCs) are impaired in diabetes. This study aimed to investigate the direct effects of high glucose on EPCs...
  24. ncbi Effect of invasive strategy on different genders of Chinese patients with non-ST-elevation myocardial infarction
    Shao Sung Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Catheter Cardiovasc Interv 79:946-55. 2012
    ....
  25. ncbi Ginkgo biloba extract inhibits endotoxin-induced human aortic smooth muscle cell proliferation via suppression of toll-like receptor 4 expression and NADPH oxidase activation
    Feng Yen Lin
    Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China
    J Agric Food Chem 55:1977-84. 2007
    ..These results suggest that LPS-induced TLR4 expression contributes to HASMC proliferation and that G. biloba inhibits LPS-stimulated proliferation of HASMCs by decreasing TLR4 expression...
  26. ncbi Niacin improves ischemia-induced neovascularization in diabetic mice by enhancement of endothelial progenitor cell functions independent of changes in plasma lipids
    Po Hsun Huang
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan
    Angiogenesis 15:377-89. 2012
    ..Our findings demonstrate that niacin increases blood flow recovery after tissue ischemia in diabetic mice through enhancing EPC mobilization and functions via nitric oxide-related pathways...
  27. ncbi Decreased heparin cofactor II activity is associated with impaired endothelial function determined by brachial ultrasonography and predicts cardiovascular events
    Po Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Int J Cardiol 114:152-8. 2007
    ..However, the relation between plasma HCII activity and peripheral vascular endothelial function remains unclear...
  28. ncbi Multimarker approach to risk stratification among patients with advanced chronic heart failure
    Wei Hsian Yin
    Division of Cardiology, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
    Clin Cardiol 30:397-402. 2007
    ..However, little is known about the utility of these novel biomarkers of CHF in combination...
  29. ncbi Superoxide dismutase and catalase inhibit oxidized low-density lipoprotein-induced human aortic smooth muscle cell proliferation: role of cell-cycle regulation, mitogen-activated protein kinases, and transcription factors
    Shing Jong Lin
    Institute of Clinical Medicine, National Yang Ming University, Taiwan, Republic of China
    Atherosclerosis 190:124-34. 2007
    ..These observations support the feasibility of the increase of Cu, Zn-SOD and/or catalase expression in human smooth muscle cells as a means of protection against oxidant injury...
  30. ncbi Increased circulating CD31+/annexin V+ apoptotic microparticles and decreased circulating endothelial progenitor cell levels in hypertensive patients with microalbuminuria
    Po Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Institute of Clinical Medicine, Cardiovascular Research Center, National Yang Ming University, Taipei, Taiwan
    J Hypertens 28:1655-65. 2010
    ....
  31. ncbi A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes
    Chia Min Chung
    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
    Diabetes 60:2417-23. 2011
    ..Therefore, we aimed not only to identify genetic variants modulating plasma adiponectin levels but also to investigate whether these variants are associated with adiponectin-related metabolic traits and cardiovascular diseases...
  32. ncbi Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis
    Tao Cheng Wu
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Free Radic Biol Med 43:1508-22. 2007
    ..Accordingly, carvedilol, a pharmacological antioxidant, inhibited in vivo and in vitro expression of MMP-2 and MMP-9 properly by modulating the redox-related pathways, suggesting its potential clinical implications...
  33. ncbi Combination of an ACE inhibitor and indapamide improves blood pressure control, but attenuates the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension
    Shao Sung Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Circ J 73:2282-7. 2009
    ....
  34. ncbi Cholestin (Monascus purpureus rice) inhibits homocysteine-induced reactive oxygen species generation, nuclear factor-kappaB activation, and vascular cell adhesion molecule-1 expression in human aortic endothelial cells
    Chih Pei Lin
    Institute of Public Health, National Yang Ming University, No 155, Sec 2, Linong St, Peitou, Taipei, 112, Taiwan
    J Biomed Sci 15:183-96. 2008
    ....
  35. ncbi Association of adiponectin with future cardiovascular events in patients after acute myocardial infarction
    Shao Sung Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Atheroscler Thromb 17:295-303. 2010
    ..The goal of this study was to determine whether plasma adiponectin levels could predict future cardiovascular events in patients after AMI, and to elucidate the role of adiponectin in cardioprotection...
  36. ncbi Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients
    Ying Hwa Chen
    Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
    Hum Genet 111:1-8. 2002
    ..Type 2 diabetics carrying longer (GT) (n) repeats might have higher oxidative stress and increased susceptibility to the development of CAD...
  37. ncbi Zoledronate inhibits ischemia-induced neovascularization by impairing the mobilization and function of endothelial progenitor cells
    Shih Hung Tsai
    Department of Emergency Medicine, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
    PLoS ONE 7:e41065. 2012
    ..Whether the nitrogen-containing bisphosphonate zoledronate inhibits ischemia-induced neovascularization by modulating EPC functions remains unclear...
  38. ncbi Systemic sclerosis and risk of ischaemic stroke: a nationwide cohort study
    Chia Hung Chiang
    Healthcare and Management Center, Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan, No 201, Sec 2, Shi Pai Road, Taipei, Taiwan, R O C
    Rheumatology (Oxford) 52:161-5. 2013
    ..To investigate whether SSc increases the risk of ischaemic stroke in a large, nationwide cohort study...
  39. ncbi A two-stage matched case-control study on multiple hypertensive candidate genes in Han Chinese
    Tai Yue Kuo
    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
    Am J Hypertens 25:804-11. 2012
    ..It is a major risk factor leading to stroke, cardiovascular disease, and end-stage renal disease. In each year, more than 13.5 million deaths are due to hypertension-related diseases worldwide...
  40. ncbi Assessment of first-year post-graduate residents: usefulness of multiple tools
    Ying Ying Yang
    Division of General Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 74:531-8. 2011
    ....
  41. ncbi The role of human antigen R, an RNA-binding protein, in mediating the stabilization of toll-like receptor 4 mRNA induced by endotoxin: a novel mechanism involved in vascular inflammation
    Feng Yen Lin
    Graduate Institute of Medical Sciences, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
    Arterioscler Thromb Vasc Biol 26:2622-9. 2006
    ..It is not know whether the RNA-binding protein, human antigen R (HuR), regulates TLR4 expression in human aortic smooth muscle cells (HASMCs)...
  42. ncbi Serum bilirubin predicts long-term clinical outcomes in patients with cardiac syndrome X
    Shao Sung Huang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Heart 96:1227-32. 2010
    ..This study was conducted to evaluate the prognostic role of serum bilirubin in disease progression and clinical outcome in patients with CSX...
  43. ncbi Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells
    Shing Jong Lin
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
    J Cell Biochem 100:372-84. 2007
    ..This novel mechanism of action of Sal B, in addition to its previously reported inhibition of LDL oxidation, may help explain its efficacy in the treatment of atherosclerosis...
  44. ncbi Decreased circulating endothelial progenitor cell levels and function in patients with nonalcoholic fatty liver disease
    Chia Hung Chiang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    PLoS ONE 7:e31799. 2012
    ..Here, we tested the hypothesis that patients with nonalcoholic fatty liver disease (NAFLD) might have decreased endothelial progenitor cell (EPC) levels and attenuated EPC function...
  45. ncbi Oral alendronate use and risk of cancer in postmenopausal women with osteoporosis: A nationwide study
    Chia Hung Chiang
    Division of Cardiology, Department of Medicine, Zhudong Veterans Hospital, Hsinchu, Taiwan
    J Bone Miner Res 27:1951-8. 2012
    ..05; 95% confidence interval [CI], 0.97-1.13; p = 0.237). However, due to the limited study size and underpowered results, further larger prospective studies or meta-analysis are suggested to further confirm our findings...
  46. ncbi Association of serum bilirubin with contrast-induced nephropathy and future cardiovascular events in patients undergoing coronary intervention
    Shao Sung Huang
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    PLoS ONE 7:e42594. 2012
    ..Bilirubin has emerged as an important endogenous antioxidant molecule. This study was undertaken to determine whether bilirubin is associated with CIN and future cardiovascular events in patients undergoing coronary intervention...
  47. ncbi Baseline plasma glycemic profiles but not inflammatory biomarkers predict symptomatic restenosis after angioplasty of arteriovenous fistulas in patients with hemodialysis
    Chih Cheng Wu
    Department of Medicine, Hsinchu General Hospital, Hsinchu, Taiwan, ROC
    Atherosclerosis 209:598-600. 2010
    ....
  48. ncbi Decreased circulating endothelial progenitor cell levels and function in essential hypertensive patients with electrocardiographic left ventricular hypertrophy
    Ching Wei Lee
    Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Hypertens Res 34:999-1003. 2011
    ..These findings may explain the pathogenetic processes that link hypertensive LVH and endothelial injury in cardiovascular disease...
  49. ncbi Usefulness of combined high-sensitive C-reactive protein and N-terminal-probrain natriuretic peptide for predicting cardiovascular events in patients with suspected coronary artery disease
    Po Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Coron Artery Dis 19:187-93. 2008
    ..We examined whether the combined use of high-sensitive C-reactive protein (hsCRP) and N-terminal-probrain natriuretic peptide (NT-proBNP) could increase the predictive value for future cardiovascular events...
  50. ncbi Usefulness of plasma matrix metalloproteinase-9 level in predicting future coronary revascularization in patients after acute myocardial infarction
    Ko Fan Wang
    Division of Cardiology, Taipei Veterans General Hospital, Taiwan
    Coron Artery Dis 24:23-8. 2013
    ..This study aims to determine whether plasma levels of matrix metalloproteinases (MMPs) and inflammatory markers can predict the long-term prognosis of coronary revascularization in patients after acute myocardial infarction (AMI)...
  51. ncbi Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis
    Vin Cent Wu
    Department of Internal Medicine, Taipei Veterans General Hospital and Cardiovascular Research Center, National Yang Ming University, Taipei 100, Taiwan
    J Clin Endocrinol Metab 96:3175-83. 2011
    ..Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)...
  52. ncbi Angiotensin II receptor blockers and risk of cancer in patients with systemic hypertension
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    Am J Cardiol 107:1028-33. 2011
    ..66, 95% confidence interval 0.63 to 0.68, p <0.001). In conclusion, long-term use of ARBs is associated with a lower incidence of cancer occurrence, thereby suggesting that ARBs may prevent cancer development...
  53. ncbi Plasma heparin cofactor II activity is an independent predictor of future cardiovascular events in patients after acute myocardial infarction
    Shao Sung Huang
    Department of Internal Medicine, Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan
    Coron Artery Dis 19:597-602. 2008
    ....
  54. ncbi Genetic variation in renin predicts the effects of thiazide diuretics
    Chin Chou Huang
    Department of Medical Research and Education Division of Cardiology, Department of Medicine, Taipei, Taiwan
    Eur J Clin Invest 41:828-35. 2011
    ..This study aimed to address the potential effects of genetic variations of RAAS on the response to initial treatment of hydrochlorothiazide (HCTZ)...
  55. ncbi Genome-wide scan for quantitative ACE activity in Taiwan young-onset hypertension study
    Ruey Yun Wang
    Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan, ROC
    Hum Hered 65:85-90. 2008
    ..The purpose of this study was to map quantitative trait loci (QTL) for serum ACE activity, a heritable endophenotype of cardiovascular diseases (estimated heritability = 0.58)...
  56. ncbi Nonpeptic ulcer, nonvariceal gastrointestinal bleeding in hemodialysis patients
    Jiing Chyuan Luo
    Department of Medicine, National Yang Ming University, School of Medicine, Taipei City, Taiwan
    Am J Med 126:264.e25-32. 2013
    ..Hemodialysis patients carry a higher risk of peptic ulcer bleeding. Whether hemodialysis patients also have a higher occurrence of nonpeptic ulcer, nonvariceal gastrointestinal bleeding needs further evaluation...
  57. ncbi Gastroesophageal reflux disease and atrial fibrillation: a nationwide population-based study
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    PLoS ONE 7:e47575. 2012
    ..The association between gastroesophageal reflux disease (GERD), the most common gastroesophageal disorder, and AF remains undetermined. We therefore aimed to investigate the association between GERD and later development of AF...
  58. ncbi Genetic variation in C-reactive protein in ethnic Chinese population in Taiwan
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan Cardiovascular Research Center, National Yang Ming University, Taipei, Taiwan Institute of Pharmacology, National Yang Ming University, Taipei, Taiwan
    Eur J Clin Invest 43:449-56. 2013
    ..This study aimed to assess the potential genetic determinants for serum hs-CRP levels in a cohort with well-controlled nondiabetic hypertension...
  59. ncbi Angiotensin-receptor blockers and risk of Alzheimer's disease in hypertension population
    Chien Yi Hsu
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital
    Circ J 77:405-10. 2013
    ..222) were independently associated with AD development. Conclusions: The use of ARB was not significantly associated with a reduction of risk of AD in Asian patients with essential hypertension.  (Circ J 2013; 77: 405-410)...
  60. ncbi Effects of annual influenza vaccination on mortality and hospitalization in elderly patients with ischemic heart disease: a nationwide population-based study
    I Fan Liu
    Department of Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan, Taiwan
    Prev Med 54:431-3. 2012
    ..The purpose of this study was to evaluate the effects of influenza vaccination on all-cause mortality and hospitalization for cardiovascular disease in elderly IHD patients...
  61. ncbi Association between Mycoplasma pneumonia and increased risk of ischemic stroke: a nationwide study
    Chia Hung Chiang
    Department of Medicine, Healthcare and Management Center, Taipei Veterans General Hospital, and National Yang Ming University, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan
    Stroke 42:2940-3. 2011
    ..Infections have been hypothesized to play a role in vascular disease. The association between Mycoplasma pneumoniae (MP) infection and ischemic stroke remained undetermined...
  62. ncbi Statin use and hospitalization in patients with chronic obstructive pulmonary disease: a nationwide population-based cohort study in Taiwan
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    Clin Ther 33:1365-70. 2011
    ..There is new evidence suggesting that statins have beneficial effects on patients with chronic obstructive pulmonary disease (COPD), which is characterized by a persistent inflammatory response...
  63. ncbi Adiponectin gene polymorphism is selectively associated with the concomitant presence of metabolic syndrome and essential hypertension
    Hsin Bang Leu
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, ROC
    PLoS ONE 6:e19999. 2011
    ..Although the adiponectin (ADIPOQ) gene has been reported to be involved in MetS, its association with HTN remained undetermined. This study aimed to investigate the association of ADIPOQ gene with the phenotypes of HTN and MetS...
  64. ncbi Baseline serum matrix metalloproteinase-9 level predicts long-term prognosis after coronary revascularizations in stable coronary artery disease
    Zhong Xuan Ye
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
    Clin Biochem 41:292-8. 2008
    ..This study aimed to investigate whether baseline serum levels of matrix metalloproteinases (MMPs) could predict long-term prognosis of coronary revascularizations...
  65. ncbi Increased endothelial monocyte adhesiveness is related to clinical outcomes in chronic heart failure
    Wei Hsian Yin
    Division of Cardiology, Department of Internal Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei Veterans General Hospital, Taiwan
    Int J Cardiol 121:276-83. 2007
    ..In the present study, we investigated the clinical significance of the activity of PBMCs in patients with CHF...
  66. ncbi Heme oxygenase-1 gene promotor microsatellite polymorphism is associated with angiographic restenosis after coronary stenting
    Ying Hwa Chen
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, 201 Sec 2 Shih Pai Road, Taipei 112, Taiwan, ROC
    Eur Heart J 25:39-47. 2004
    ..This study aimed to assess the association of the length of (GT)(n)repeats in HO-1 gene promotor with restenosis and adverse cardiac events after coronary stenting...
  67. ncbi Magnolol attenuates VCAM-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in the aorta of cholesterol-fed rabbits
    Yung-Hsiang Chen
    Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan
    Br J Pharmacol 135:37-47. 2002
    ..These results suggest that magnolol has anti-inflammatory properties and may play important roles in the prevention of atherosclerosis and inflammatory responses in vivo...
  68. ncbi Prognostic value of circulating adipokine levels and expressions of adipokines in the myocardium of patients with chronic heart failure
    Wei Hsian Yin
    Heart Center, Cheng Hsin General Hospital, Taipei, Taiwan
    Circ J 76:2139-47. 2012
    ..The aim of this study was to ascertain whether expressions of adipokines in the myocardium or their circulating levels can provide prognostic information concerning patients with chronic heart failure (HF)...
  69. ncbi Hip fracture and risk of acute myocardial infarction: a nationwide study
    Chia Hung Chiang
    Division of Cardiology, Department of Medicine, Zhudong Veterans Hospital, Hsinchu, Taiwan
    J Bone Miner Res 28:404-11. 2013
    ..29; 95% confidence interval [CI] 1.12-1.48; p < 0.001). We conclude that hip fracture is independently associated with a higher risk of subsequent AMI...
  70. ncbi Predictors of inexplicable coronary artery spasm during coronary angiography in patients with stable angina--the role of intravascular oxidative stress
    Hsin Bang Leu
    National Yang Ming University School of Medicine, Cardiovascular Research Center and Institute of Clinical Medicine, Taipei, Taiwan, ROC
    Clin Biochem 42:570-7. 2009
    ..This study was conducted to investigate the potential role of intravascular oxidative stress in inexplicable episodes of coronary artery spasm (CAS) during coronary angiography (CAG)...
  71. ncbi Efficacy of a very-low-dose combination of perindopril and indapamide--preterax compared with cilazapril monotherapy in patients with inadequate blood pressure control--a randomized, double-blind, add-on study
    Shih Hsien Sung
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 71:247-53. 2008
    ....
  72. ncbi Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides
    Pei Chen
    Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, Taiwan, R O C
    Hum Mutat 30:49-55. 2009
    ..In conclusion, this study strongly suggests that two LPL intronic variants may be associated with development of the hypertension endophenotype with elevated TG...
  73. ncbi Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity
    Shing Jong Lin
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
    J Cell Biochem 101:642-53. 2007
    ....
  74. ncbi Estimation of central systolic blood pressure using an oscillometric blood pressure monitor
    Hao Min Cheng
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan
    Hypertens Res 33:592-9. 2010
    ..8) mm Hg for the noninvasive model. Thus, our results indicate that central aortic systolic blood pressure could be estimated by analysis of the noninvasive brachial pressure wave alone from an oscillometric blood pressure monitor...
  75. ncbi Genetic variants of connexin37 are associated with carotid intima-medial thickness and future onset of ischemic stroke
    Hsin Bang Leu
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Atherosclerosis 214:101-6. 2011
    ..This study aimed to investigate the impacts of genetic variants on IMT and future development of ischemic stroke in a cohort, followed by an independent replication study...
  76. ncbi Association between panic disorder and risk of atrial fibrillation:a nationwide study
    Ya Fen Cheng
    Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
    Psychosom Med 75:30-5. 2013
    ..The aim of the present study was to investigate the association between panic disorder (PD) and atrial fibrillation (AF)...
  77. ncbi Increased risk of ischemic stroke in patients with systemic lupus erythematosus: a nationwide population-based study
    Chun Chih Chiu
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
    Intern Med 51:17-21. 2012
    ..Our study investigated the relationship of SLE and the subsequent development of ischemic stroke using a nationwide, population-based database in an Asian population...
  78. ncbi Statin use in patients with asthma: a nationwide population-based study
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taiwan
    Eur J Clin Invest 41:507-12. 2011
    ..We hypothesized that statins could inhibit airway inflammation. The aim of our study was to determine whether statin use may reduce hospitalization in patients with asthma...
  79. ncbi Clinical instructors' perception of a faculty development programme promoting postgraduate year-1 (PGY1) residents' ACGME six core competencies: a 2-year study
    Fa Yauh Lee
    Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    BMJ Open 1:e000200. 2011
    ....
  80. ncbi Association of serum bilirubin levels with albuminuria in patients with essential hypertension
    Shao Sung Huang
    Department of Internal Medicine, Taoyuan Veterans Hospital, Taipei, Taiwan
    Clin Biochem 44:859-63. 2011
    ..This study was undertaken to evaluate the relationship between serum bilirubin concentrations and the degree of urinary albumin excretion in hypertensive patients...
  81. ncbi Glucose and non-glucose predictors of future onset of type 2 diabetes in newly diagnosed essential hypertensives
    Man Cai Fong
    Division of Cardiology, Department of Medicine, Taipei Hospital, Department of Health, Taipei, Taiwan, R O C
    J Chin Med Assoc 72:564-72. 2009
    ..Other predictors have been less investigated. This study aimed to investigate non-glucose predictors together with FPG for future onset of type 2 DM in fresh essential hypertensives...
  82. ncbi Predictive value of predischarge spectral tissue doppler echocardiography and n-terminal pro-B-type natriuretic peptide in patients hospitalized with acute heart failure
    Shuenn Jiin Ho
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital Division of Cardiology, Department of Internal Medicine, Cheng Hsin General Hospital Institute of Emergency and Critical Care Medicine, National Yang Ming University, School of Medicine, Taipei, Taiwan
    Echocardiography 28:303-10. 2011
    ....
  83. ncbi Risk of adverse outcomes in Taiwan associated with concomitant use of clopidogrel and proton pump inhibitors in patients who received percutaneous coronary intervention
    Chin Chou Huang
    Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Am J Cardiol 105:1705-9. 2010
    ..35 to 2.01, p <0.001). In conclusion, the concomitant use of clopidogrel and PPIs should be done with care to avoid adverse outcome in East Asians patients who have undergone percutaneous coronary intervention...
  84. ncbi Anti-inflammatory strategies for homocysteine-related cardiovascular disease
    Chih Pei Lin
    Faculty of Biotechnology and Laboratory Science in Medicine, Institute of Biotechnology in Medicine, National Yang Ming University, Taipei, Taiwan
    Front Biosci 14:3836-45. 2009
    ....
  85. ncbi Circulating mononuclear superoxide production and inflammatory markers for long-term prognosis in patients with cardiac syndrome X
    Hsin-Bang Leu
    Cardiovascular Research Center and Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei 112, Taiwan, Republic of China
    Free Radic Biol Med 40:983-91. 2006
    ..Basal superoxide production of MNCs independently predicts future cardiovascular events, suggesting its potential role in measuring disease progression and risk stratification in these patients...
  86. ncbi Application of the Sequential Organ Failure Assessment score for predicting mortality in patients with acute myocardial infarction
    Shao Sung Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Resuscitation 83:591-5. 2012
    ..This study was undertaken to determine whether the Sequential Organ Failure Assessment (SOFA) score had good accuracy for predicting mortality in AMI patients, and to compare the discriminatory performance of the 3 risk scores (RSs)...
  87. ncbi Differential mononuclear cell activity and endothelial inflammation in coronary artery disease and cardiac syndrome X
    Chih-Pei Lin
    Department of Pathology, Taipei Veterans General Hospital, 201 Shih-Pai Road Section 2, Taipei, Taiwan 11217, ROC
    Int J Cardiol 89:53-62. 2003
    ..The relatively preserved lipid and metabolic profiles might contribute to less vascular inflammation in syndrome X patients...
  88. ncbi L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery disease
    Wei-Hsian Yin
    Division of Cardiology, Cheng-Hsin General Hospital, and Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
    Clin Nutr 24:988-97. 2005
    ..1% (P=0.045) after consumption of L-arginine for 4 weeks. CONCLUSIONS: Oral L-arginine supplement improved endothelial function and reduced LDL oxidation in stable CAD patients...
  89. ncbi Indicators associated with coronary atherosclerosis in metabolic syndrome
    Ting Yu Chiu
    Cardiovascular Research Center, and School of Medicine, National Yang Ming University, Taipei, Taiwan, ROC
    Clin Chim Acta 413:226-31. 2012
    ..Metabolic factors associated with coronary atherosclerosis (CA) in metabolic syndrome (MetS) remain unclear...
  90. ncbi Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients
    Ying Hwa Chen
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Diabetes Care 31:1615-20. 2008
    ..The aim of this study was to assess the association of the length of (GT)(n) repeats in the HO-1 gene promoter with serum bilirubin, markers of iron status, and the development of coronary artery disease (CAD)...
  91. ncbi Plasma levels of soluble receptor for advanced glycation end products are associated with endothelial function and predict cardiovascular events in nondiabetic patients
    Kuang Hsing Chiang
    Department of Internal Medicine, Division of Cardiology, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, Republic of China
    Coron Artery Dis 20:267-73. 2009
    ..We sought to test the hypothesis that decreased plasma soluble receptor for advanced glycation end products (sRAGE) levels were associated with endothelial dysfunction in nondiabetic patients...
  92. ncbi A core competence-based objective structured clinical examination (OSCE) in evaluation of clinical performance of postgraduate year-1 (PGY₁) residents
    Ying Ying Yang
    Division of General Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
    J Chin Med Assoc 74:198-204. 2011
    ....
  93. ncbi The severity of non-alcoholic fatty liver disease correlates with high sensitivity C-reactive protein value and is independently associated with increased cardiovascular risk in healthy population
    Chia Hung Chiang
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Clin Biochem 43:1399-404. 2010
    ..We aimed to investigate the correlation between non-alcoholic fatty liver disease (NAFLD) and risk of cardiovascular disease (CVD)...
  94. ncbi Effects of Ginkgo biloba extract on the proliferation of vascular smooth muscle cells in vitro and on intimal thickening and interleukin-1beta expression after balloon injury in cholesterol-fed rabbits in vivo
    Shing-Jong Lin
    Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
    J Cell Biochem 85:572-82. 2002
    ..The inhibitory effects of EGb on the intimal response might be attributed to its antioxidant capacity. EGb may have therapeutic potential for the prevention of restenosis after angioplasty...
  95. ncbi Plasma ADMA predicts restenosis of arteriovenous fistula
    Chih Cheng Wu
    Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan, Republic of China
    J Am Soc Nephrol 20:213-22. 2009
    ....
  96. ncbi Impairment of coronary microvascular function in patients with neurally mediated syncope
    Jaw-Wen Chen
    Div. of Cardiology, Dept. of Medicine, Taipei Veterans General Hospital 201, Shih-Pai Rd, Section 2, Taipei, Taiwan 11217, Republic of China
    Pacing Clin Electrophysiol 26:605-12. 2003
    ....
  97. ncbi Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules
    Yung-Hsiang Chen
    Institute of Clinical Medicine, National Yang-Ming University, Taiwan, Republic of China
    Cardiovasc Hematol Disord Drug Targets 6:279-304. 2006
    ..The inhibition of endothelial adhesion molecule expression by drugs/agents with antioxidant activity may serve as a potential therapeutic strategy for clinical atherosclerosis...
  98. ncbi The prognostic value of circulating soluble cell adhesion molecules in patients with chronic congestive heart failure
    Wei-Hsian Yin
    Division of Cardiology, Cheng-Hsin General Hospital, 45, Cheng-Hsin Street, Pei-Tou, Taipei, Taiwan, ROC
    Eur J Heart Fail 5:507-16. 2003
    ..Among them, high levels of sP-selectin can provide prognostic information independently in patients with CHF...
  99. ncbi Usefulness of attenuated heart rate recovery immediately after exercise to predict endothelial dysfunction in patients with suspected coronary artery disease
    Po-Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Am J Cardiol 93:10-3. 2004
    ..7%, p = 0.006), but responses to sublingual nitroglycerin showed no difference among the 3 groups (p = 0.332). According to multivariate analysis, heart rate recovery after exercise was an independent predictor of endothelial function...
  100. ncbi Heart rate recovery after exercise and endothelial function--two important factors to predict cardiovascular events
    Po-Hsun Huang
    Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    Prev Cardiol 8:167-70; quiz 171. 2005
    ..This review focuses on the roles of heart rate recovery and endothelial function in predicting future mortality and their interaction...
  101. ncbi Fluvastatin reduces oxidative stress, decreases serum monocyte chemotactic protein-1 level and improves endothelial function in patients with hypercholesterolemia
    Hsin-Bang Leu
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Formos Med Assoc 103:914-20. 2004
    ..These observations provide a clinical rationale for the co-existence of complex and multiple vascular protective mechanisms of statins...