Research Topics
Genomes and Genes | F Y ChangSummaryAffiliation: Taipei Veterans General Hospital Country: Taiwan Publications
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Publications
Undisturbed water gastric emptying in patients of stomach cancerFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine National Yang Ming University, Taipei, Taiwan, Republic of China
Hepatogastroenterology 51:1219-24. 2004..It is of interest whether the stomach motility in gastric cancer patients may be altered. We employed a homemade applied potential tomographic system to study the features of water gastric emptying in gastric cancer patients...- What is the essential role in the normalized rat intestinal transit? Calcium or calcitoninF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital, 201 Shih Pai Road, Section 2, Taipei, Taiwan 11217, ROC
Hepatogastroenterology 48:143-6. 2001..Both calcium and calcitonin have been involved in mediating gastrointestinal motility. Using a thyroidectomized rat model the present study tried to determine which one of them was essential for normal small intestinal transit... - Vasoactive intestinal polypeptide appears to be one of the mediators in misoprostol-enhanced small intestinal transit in ratsF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital, National Yang Ming University, Taiwan
J Gastroenterol Hepatol 15:1120-4. 2000..It remains unknown whether some gut peptides also mediate this enhancement. We studied the effect of misoprostol on rat SIT and looked at the role of vasoactive intestinal polypeptide (VIP) release during its action... - Acid-inhibitory potency of ranitidine in diabetic ratsFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Pharmacology 66:5-10. 2002..1 vs. 55.1 +/- 4.2%, p < 0.05). In conclusion, short-term diabetes induction in rats enhances their stimulatory acid output ability, but attenuates the pharmacologically inhibitory action of ranitidine on the stimulated acid output... - Calcium rather than calcitonin is dominant to mediate gastric emptying in thyroidectomized ratsF Y Chang
Division of Gastroenterology, Veterans General Hospital Taipei, Taiwan, ROC
Chin J Physiol 42:189-93. 1999..We suggest that calcium rather than calcitonin is dominant to mediate gastric emptying... - Response of blood endothelin-1 and nitric oxide activity in duodenal ulcer patients undergoing Helicobacter pylori eradicationFull Young Chang
Chief, Division of Gastroenterology, Taipei Veterans General Hospital, 201, Section 2, Shih Pai Road, Taipei 112, Taiwan, China
World J Gastroenterol 11:1048-51. 2005..To investigate the effect of Helicobacter pylori eradication on endothelin-1 (ET-1) and nitric oxide (NO) in duodenal ulcer (DU) patients... - Pentagastrin-induced gastric acid secretion in the diabetic rats: role of insulinFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Chin J Physiol 47:175-81. 2004..This effect appears to be responsible for the excessive acid output of diabetic rats undergoing pentagastrin stimulation... - Electrogastrography: basic knowledge, recording, processing and its clinical applicationsFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 20:502-16. 2005..Understanding basic SW physiology, recording methodology and indications may open EGG as a new domain to approach the stomach motor dysfunction... - Variation of capsaicin-sensitive motor activities along the rat gastrointestinal tractF Y Chang
Division of Gastroenterology, Veterans General Hospital, Taipei, Taiwan, ROC
Chin J Physiol 42:41-5. 1999..We confirm the notion of variation in capsaicin-sensitive motor responses along the rat upper digestive organ... - Rat small intestinal transit is independent of glucose consumption in the strenuous exerciseFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan, Republic of China
Chin J Physiol 49:169-73. 2006..Glucose utilization and lactate accumulation after the strenuous exercise may not directly mediate small intestinal motility... - Rat gastrointestinal motor responses mediated via activation of neurokinin receptorsF Y Chang
Division of Gastroenterology, Veterans General Hospital Taipei, Taiwan, Republic of China
J Gastroenterol Hepatol 14:39-45. 1999..This selective activation of stomach NK1 and NK2 receptors delays gastric emptying, whereas activation of intestinal NK1 and NK3 receptors enhances intestinal transit... - Interaction of carbohydrate metabolism and rat liquid gastric emptying in sustained runningFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 21:831-6. 2006..It is unknown whether the carbohydrate metabolism of runners can influence gastric emptying (GE). Using a running rat model, the present study explored the impact of exercise/carbohydrate metabolism on liquid GE... - Irritable bowel syndrome in the 21st century: perspectives from Asia or South-east AsiaFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 22:4-12. 2007..In conclusion, Western recommended criteria clearly diagnose Asian IBS and many factors are mutual leading to IBS. Current IBS treatments remain useful but additional reeducation for medical professionals appears to be needed... - The pharmacological effect of omeprazole on water gastric emptying: A study based on an impedance measureF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
Pharmacology 63:50-7. 2001..The interpretation of impedance-obtained GE should consider the acid-inhibitory effect... - An improved electrogastrographic system in measuring myoelectrical parametersF Y Chang
Division of Gastroenterology, Veterans General Hospital Taipei and National Yang Ming University, Taiwan, China
J Gastroenterol Hepatol 13:1027-32. 1998..3+/-88.8% (16-478%, median 88%). This new EGG system is, indeed, reliable for measuring myoelectrical frequency and power, whereas the interassay of recorded amplitudes appears markedly variable... - Fasting and postprandial small intestinal slow waves non-invasively measured in subjects with total gastrectomyFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan
J Gastroenterol Hepatol 22:247-52. 2007..The aims of this study were to determine the origin of 3 cycles per min (cpm) slow wave recorded via electrogastrogram (EGG) and the characteristics of putative small intestinal slow waves in TG subjects... - Efficacy of dioctahedral smectite in treating patients of diarrhea-predominant irritable bowel syndromeFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine, National Yang Ming University, Taipei, Taiwan
J Gastroenterol Hepatol 22:2266-72. 2007..The aim of this study was to determine DS efficacy on patients with diarrhea-predominant irritable bowel syndrome (D-IBS in a phase III-, 8-week-randomized, double-blind, placebo-controlled trial... 
Treatment of irritable bowel syndrome using complementary and alternative medicineFull Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan, R O C
J Chin Med Assoc 72:294-300. 2009..Apart from conventional medications, CAM may be considered individually as a supplement or alternative to treat IBS patients that is at least equal in effect to placebo if patients do not exhibit any intolerable or serious side effects...- Sequential transarterial chemoembolization and percutaneous acetic acid injection therapy versus repeated percutaneous acetic acid injection for unresectable hepatocellular carcinoma: a prospective studyT I Huo
Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
Ann Oncol 14:1648-53. 2003..We have conducted a prospective study to compare the efficacy of sequential TACE and PAI (TACE-PAI) versus repeated PAI therapy for HCC... - Comparison of recurrence after hepatic resection in patients with hepatitis B vs. hepatitis C-related small hepatocellular carcinoma in hepatitis B virus endemic areaYi-Hsiang Huang
Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
Liver Int 25:236-41. 2005..CONCLUSIONS: HCV infection, as compared with HBV infection, had a higher cumulated recurrence after hepatic resection in patients with small HCC. Low serum albumin level was significantly associated with recurrence among these patients... - Inhibition of prostacyclin by indomethacin ameliorates the splanchnic hyposensitivity to glypressin in haemorrhage-transfused common bile duct-ligated ratsF Y Lee
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Road, Taipei, Taiwan 11217, Republic of China
Eur J Clin Invest 31:145-53. 2001..001) in bleeding BDL rats. Splanchnic hyposensitivity to glypressin observed in haemorrhage-transfused BDL rats could be ameliorated by the addition of indomethacin, suggesting a role of endogenous PGI2 in its pathophysiology... - Gender difference on the symptoms, health-seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II-based survey in an apparent healthy adult Chinese population in TaiwanC L Lu
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan
Aliment Pharmacol Ther 21:1497-505. 2005..Little is known about the gender effect on irritable bowel syndrome in Asia... - Hepatic steatosis in chronic hepatitis C virus infection: prevalence and clinical correlationS J Hwang
Department of Medicine, Veterans General Hospital Taipei, National Yang Ming University School of Medicine, Taiwan, Republic of China
J Gastroenterol Hepatol 16:190-5. 2001.... - Impaired postprandial gastric myoelectrical activity in Chinese patients with nonulcer dyspepsiaC L Lu
Department of Medicine and Surgery, Taipei Veterans General Hospital and School of Medicine, National Yang-Ming University, Taiwan
Dig Dis Sci 46:242-9. 2001.... - Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive ratsC C Chan
Divisions of Gastroenterology and General Medicine, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine, Taipei, Taiwan, Republic of China
Hepatology 33:816-20. 2001..This effect is mediated by ET(A,) but not ET(B), receptors. Both nitric oxide and prostaglandin modulate the collateral vascular response to ET-1 and may therefore participate in the development and maintenance of portal hypertension... - Induction of complete tumor necrosis may reduce intrahepatic metastasis and prolong survival in patients with hepatocellular carcinoma undergoing locoregional therapy: a prospective studyT I Huo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Ann Oncol 15:775-80. 2004..This study aimed to investigate whether HCC patients who had initial complete response to these treatments had a subsequent lower risk of intrahepatic metastasis... - Adaptive vasodilatory response after octreotide treatmentY Y Yang
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taiwan
Am J Physiol Gastrointest Liver Physiol 281:G117-23. 2001..The enhanced endothelium-related vasodilatory activity was noted after octreotide treatment that overcame the octreotide-induced hemodynamic effects in portal hypertension... - Cirrhotic patients at increased risk of peptic ulcer bleeding: a nationwide population-based cohort studyJ C Luo
Department of Medicine, National Yang Ming University, School of Medicine, Taipei City, Taiwan
Aliment Pharmacol Ther 36:542-50. 2012..Few large population-based studies have compared the occurrence of peptic ulcer bleeding (PUB) in cirrhotic and noncirrhotic patients... - Comparison of clinical, virologic and pathologic features in patients with acute hepatitis B and CC W Chu
Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taiwan, Republic of China
J Gastroenterol Hepatol 16:209-14. 2001.... - Acute renal failure after transarterial chemoembolization for hepatocellular carcinoma: a retrospective study of the incidence, risk factors, clinical course and long-term outcomeT I Huo
Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
Aliment Pharmacol Ther 19:999-1007. 2004..Transarterial chemoembolization is effective for hepatocellular carcinoma. Acute renal failure may occur after transarterial chemoembolization because of radiocontrast agent, but its clinical aspects are unknown... - Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two casesC C Lin
Department of Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China
J Gastroenterol Hepatol 16:481-3. 2001..Ranitidine was the most likely drug responsible for causing Stevens-Johnson syndrome in these two patients... - Factors predictive of liver cirrhosis in patients with chronic hepatitis B: a multivariate analysis in a longitudinal studyT Huo
Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taiwan, Republic of China
Eur J Gastroenterol Hepatol 12:687-93. 2000..A total of 516 patients with chronic hepatitis B were followed up longitudinally to determine their outcome... - Misoprostol-inhibited rat gastric emptying is independent of gastric inhibitory polypeptide releaseF Y Chang
Division of Gastroenterology, Veterans General Hospital Taipei, Taiwan, Republic of
Pharmacology 58:265-9. 1999..We conclude that liquid gastric emptying is disturbed after various routes of misoprostol treatment; GIP appears less important in the misoprostol-mediated gastric emptying... - Diabetes mellitus is a risk factor for hepatic decompensation in patients with hepatocellular carcinoma undergoing resection: a longitudinal studyTeh-Ia Huo
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
Am J Gastroenterol 98:2293-8. 2003..CONCLUSION: HCC patients with DM or large tumor size are at a cumulative increased risk for postoperative hepatic decompensation... - Hepatitis B vaccination in patients with chronic hepatitis CS D Lee
Division of Gastroenterology, Department of Medicine, Veterans General Hospital Taipei, and National Yang Ming University School of Medicine, Taipei, Taiwan
J Med Virol 59:463-8. 1999..Hepatitis B vaccination is safe and immunogenic in patients with chronic hepatitis C. It did not significantly affect their levels of HCV RNA, but tended to lower ALT levels... - A 3-day anti-Helicobacter pylori therapy is a good alternative for bleeding peptic ulcer patients with Helicobacter pylori infectionY H Hsieh
Division of Gastroenterology, Department of Medicine, VGH-TAIPEI, Shih-Pai Rd, Sec 2, Taipei, Taiwan, 11217, ROC
Hepatogastroenterology 48:1078-81. 2001..1). CONCLUSIONS: In patients with peptic ulcer bleeding a 3-day anti-Helicobacter pylori therapy is a good alternative for eradicating Helicobacter pylori infection... - The motor actions of natural neurokinins and their specific agonists on the gastrointestinal tract of the ratF Y Chang
Department of Medicine, Veterans General Hospital Taipei, Taiwan, Republic of China
Chin J Physiol 35:337-48. 1992..We suggest the probable presence of NK1, NK2 and NK3 receptors in the small intestine and stomach including pylorus of the rat... - Feasibility and potential benefit of maintenance endoscopic variceal ligation in patients with unresectable hepatocellular carcinoma and acute esophageal variceal hemorrhage: a controlled trialW C Chen
Division of Gastroenterology Department of Medicine, Taipei Veterans General Hospital, and School of Medicine, National Yang-Ming University Taipei, Taiwan
Gastrointest Endosc 54:18-23. 2001..Maintenance ligation might lower the rate of recurrent bleeding in this subgroup of patients... - Real-time display of the stomach slow wave and its parameters in a newly designed electrogastrographic systemF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan
J Gastroenterol 36:10-7. 2001..This newly designed EGG system is acceptable for clinically measuring gastric myoelectrical activity; the real-time display of many EGG parameters is an advantage with this new system... - Insulin resistance is a major determinant of sustained virological response in genotype 1 chronic hepatitis C patients receiving peginterferon alpha-2b plus ribavirinC J Chu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Aliment Pharmacol Ther 29:46-54. 2009..Aim To investigate retrospectively the impact of insulin resistance on treatment response in Chinese genotype 1 CHC patients receiving a 24-week course therapy with peginterferon alpha-2b/ribavirin... - A new "sandwich" method of combined endoscopic variceal ligation and sclerotherapy versus ligation alone in the treatment of esophageal variceal bleeding: a randomized trialM C Hou
Division of Gastroenterology, Department of Medicine, Taipei-Veterans General Hospital, and National Yang-Ming University School of Medicine, Taipei, Taiwan, Republic of China
Gastrointest Endosc 53:572-8. 2001..This method is superior to ligation alone in terms of lower variceal recurrence rate and comparable to ligation with respect to hemostasis. However, it is unknown whether the lower recurrence rate of varices will persist long-term... - The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese populationWei Ping Lee
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taiwan
Clin Cancer Res 11:6431-41. 2005..Particularly, the -251A is associated with decreased risk of colorectal cancer. We aimed to determine whether the -251 allele resulting in high IL-8 expression was associated with increased risk of gastric carcinoma... - Rapid urease test from non-ulcer part of stomach is superior to histology from ulcer in detection of Helicobacter pylori infection in patients with gastric ulcerChiu-Yung Ho
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
Hepatogastroenterology 51:1877-80. 2004..pylori infection, we strongly recommend the rapid urease test from the antrum and body specimens rather than from the ulcer margins for detection of the bacteria in patients with gastric ulcer disease... - Successful initial treatment with weekly etoposide, epirubicin, cisplatin, 5-fluorouracil and leucovorin chemotherapy in advanced gastric cancer patients with disseminated intravascular coagulationY Chao
Division of Gastroenterology, Veterans General Hospital, Taipei, Taiwan
Jpn J Clin Oncol 30:122-5. 2000..The only way to correct this fatal condition is to control the underlying cancer promptly by effective chemotherapy. Here the successful initial control of acute DIC in gastric cancer patients with weekly EEPFL chemotherapy is reported... - Persistent retention of acetic acid is associated with complete tumour necrosis in patients with hepatocellular carcinoma undergoing percutaneous acetic acid injectionT I Huo
Division of Gastroenterology, Dept of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Scand J Gastroenterol 39:168-73. 2004..This study aimed to determine the occurrence and predictive value of persistent intra-tumoral retention of acetic acid after PAIT... - Comparison of transarterial chemoembolization and percutaneous acetic acid injection as the primary loco-regional therapy for unresectable hepatocellular carcinoma: a prospective surveyT Huo
Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
Aliment Pharmacol Ther 19:1301-8. 2004..Transarterial chemoembolization (TACE) and percutaneous acetic acid injection (PAI) are effective loco-regional therapies for hepatocellular carcinoma (HCC)... - Effects of sustained-release lanreotide on hemodynamics in rats with portal vein stenosisH C Lin
Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taiwan
J Hepatol 31:482-8. 1999..The current study was undertaken to evaluate the effects of lanreotide, a sustained-release somatostatin analogue, on hemodynamics in rats with portal hypertension... - Hemodynamic effects of a combination of prazosin and terlipressin in patients with viral cirrhosisW C Lee
Department of Medicine, Taipei Veterans General Hospital, Taiwan
Am J Gastroenterol 96:1210-6. 2001..However, the combined therapy did not modify the systemic hemodynamic effects exerted by terlipressin... - Portopulmonary hypertension: distinctive hemodynamic and clinical manifestationsY Y Yang
Department of Medicine, Taipei Veterans General Hospital, Taiwan
J Gastroenterol 36:181-6. 2001..This study suggested that portopulmonary hypertension was not a frequent complication in cirrhotic patients and was not associated with an adverse outcome... - A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligationPen-Chung Tan
Division of Gastroenterology, Department of Medicine, Veterans General Hospital-Taipei and National Yang-Ming University School of Medicine, Taipei, Taiwan
Hepatology 43:690-7. 2006..Severe complications attributable to these two treatments were rare. In conclusion, the efficacy of GVL to control active GVH appears not different to GVO, but GVO is associated with a lower GV rebleeding rate... 
A global emerging disease of Klebsiella pneumoniae liver abscess: is serotype K1 an important factor for complicated endophthalmitis?C P Fung
Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan
Gut 50:420-4. 2002..However, the relationship between the clinical presentation and bacterial factors remains unclear. The aim of this study was to investigate the clinical features of patients and the serotype and ribotype of K pneumoniae liver abscess...- Comparison of the nucleic acid-based crosslinking hybridization assay and the branched DNA signal amplification assay in the quantitative measurement of serum hepatitis B virus DNAS J Hwang
Department of Family Medicine, Veterans General Hospital Taipei, Taiwan
J Clin Lab Anal 13:296-300. 1999..Less time-consuming procedures and better sensitivity in the detection of HBeAg-negative samples with elevated serum alanine transaminase levels may favor the clinical use of the crosslinking assay... - Gastric inhibitory polypeptide and gastric acid secretion in pregnant ratsT S Chen
Department of Physiology, National Yang Ming University, Taipei, Taiwan, Republic of China
Placenta 16:85-92. 1995..These results suggest that the normalization of gastric acid secretion in late pregnant rats is at least in part due to the production of GIP-like substance from placenta... - Effects of long-term octreotide treatment on the response of portal-systemic collaterals to vasopressin in portal hypertensive ratsS S Wang
Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
Eur J Clin Invest 32:316-21. 2002..This study investigated the effects of long-term octreotide treatment on the response of portal-systemic collaterals to vasopressin in portal hypertensive rats... - Long-term follow-up of hepatitis A vaccination in childrenC Y Chan
Department of Medicine, Veterans General Hospital Taipei, Taiwan, ROC
Vaccine 17:369-72. 1999..05). Natural booster was noted in one vaccinee during the follow-up period. In conclusion, inactivated hepatitis A vaccine is safe and immunogenic in children, the duration of protection against HAV infection is longer than five years... - Genetic predispositions for the presence of cryoglobulinemia and serum autoantibodies in Chinese patients with chronic hepatitis CS J Hwang
Department of Family Medicine, Veterans General Hospital Taipei, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
Tissue Antigens 59:31-7. 2002..Our results suggest the existence of HLA-linked susceptibility genes (DR3 or DR4) for the development of cryoglobulinemia or serum autoantibodies in Chinese patients with chronic hepatitis C... - Effect of Helicobacter pylori eradicated therapy on water gastric emptying in patients with active duodenal ulcerFull-Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 18:1250-6. 2003..CONCLUSIONS: Water GE of active DU patients ranges from enhanced to delayed, while an effective H. pylori triple therapy is useful not only for healing ulcers, but also for restoring abnormal GE... - The prevalence and risk factors of reflux esophagitis among adult Chinese population in TaiwanTseng Shing Chen
Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang Ming University, Taipei, Taiwan, Republic of China
J Clin Gastroenterol 41:819-22. 2007..Risk factors of reflux esophagitis among Chinese in Taiwan are at present not clear and the role of Helicobacter pylori infection in the development of reflux esophagitis is still controversial... - Differential mechanism and prognostic impact of diabetes mellitus on patients with hepatocellular carcinoma undergoing surgical and nonsurgical treatmentTeh-Ia Huo
Departments of Medicine, Surgery and Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Am J Gastroenterol 99:1479-87. 2004..DM may affect the long-term survival through diabetes-related complications or inducing liver failure depending on treatment strategy and under the influence of tumoral and cirrhosis factors... - Bacteremia after endoscopic injection of N-butyl-2-cyanoacrylate for gastric variceal bleedingW C Chen
Division of Gastroenterology, Department of Medicine, and Department of Pathology and Laboratory Medicine, Taipei-Veterans General Hospital, and from National Yang-Ming University School of Medicine, Taipei, Taiwan
Gastrointest Endosc 54:214-8. 2001..CONCLUSIONS: Endoscopic cyanoacrylate injection for gastric varices does not limit the spread of bacteria. The endoscope accessory channel was the major source of bacteria. Most episodes of bacteremia were transient and uneventful... - Applied potential tomography in liquid gastric emptying measurement: design, assembling, calibration, and clinical applicationF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan, Republic of China
Dig Dis Sci 46:1839-45. 2001..9 +/- 6.3 min (r = 0.67, P < 0.01). In conclusion, our APT apparatus is a simple, noninvasive, and inexpensive way to assess liquid GE. Its clinical usefulness is confirmed using both phantom and human models... - A two dose combined hepatitis A and B vaccine in Chinese youngstersS D Lee
Department of Medicine, Veterans General Hospital Taipei, Taiwan, ROC
J Med Virol 59:1-4. 1999..It is concluded that this combined vaccine against hepatitis A and B, administered according to a two-dose schedule, is well-tolerated and highly immunogenic... - Correlation of esophageal manometry and radionuclide esophageal transit in normal subjectsF Y Chang
Division of Gastroenterology, Veterans General Hospital Taipei, Taiwan, Republic of China
Chin J Physiol 38:43-6. 1995..05). In conclusion, either manometry or scintigraphy manifests their specific benefits to diagnose esophageal motility disorders. Some correlations of measured variables can be obtained if they are simultaneously employed... - The influence of body size to the parameters of gastric slow wave: studied with an assembled electrogastrographyF Y Chang
Div of Gastroenterology, Veterans General Hospital Taipei, National Yang Ming University, Taiwan
Chin J Physiol 37:219-23. 1994..39, p < 0.005). We conclude that a different EGG power value exists between the male and female subjects, body size is probable an important factor to elicit this difference... - Silent peptic ulcer disease: frequency, factors leading to "silence," and implications regarding the pathogenesis of visceral symptomsChing-Liang Lu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
Gastrointest Endosc 60:34-8. 2004..These findings may contribute to the understanding of the pathogenesis in the visceral symptoms of peptic ulcer disease... - Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitisYi Shin Huang
Division of Gastroenterology, Department of Medicine, and Chest Department, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
Hepatology 35:883-9. 2002..Regular monitoring of serum aminotransferase levels is mandatory in patients receiving antituberculosis treatment, especially in slow acetylators... - Long-term evaluation of recombinant interferon alpha2b in the treatment of patients with hepatitis B e antigen-negative chronic hepatitis B in TaiwanC C Lin
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC
J Viral Hepat 8:438-46. 2001..Younger age and higher baseline alanine transaminase values (> or = 120 Ul(-1)) were related to 'sustained' biochemical response... - An unusual cutaneous metastasis from hepatocellular carcinomaY R Fang
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan
Zhonghua Yi Xue Za Zhi (Taipei) 64:253-7. 2001..The patient died of respiratory failure secondary to lung metastasis two months after the first appearance of the skin lesions... - Resection of triple synchronous tumors--gastric adenocarcinoma, gallbladder adenocarcinoma and stromal tumor of the stomachJ H Chen
Department of Medicine, Taipei Veterans General Hospital, Taiwan, ROC
Zhonghua Yi Xue Za Zhi (Taipei) 64:655-60. 2001..Pathological findings revealed gastric adenocarcinoma, gallbladder adenocarcinoma and stromal cell tumor of the stomach. The postoperative course was smooth... - Reliability of contemporary radiology to measure tumour size of hepatocellular carcinoma in patients undergoing resection: limitations and clinical implicationsT I Huo
Dept of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
Scand J Gastroenterol 39:46-52. 2004..However, its accuracy and reliability are unclear. This study aimed to assess the ability of current radiology to measure tumour size in patients undergoing resection... - Altered intestinal transit is independent of gastroparesis in the early diabetic ratsF Y Chang
Department of Medicine, Veterans General Hospital Taipei, Taiwan, ROC
Chin J Physiol 40:31-5. 1997..Dysmotility is probable one of factors enabled to impair the body weight gain... - Clinical, virologic, and pathologic significance of elevated serum alpha-fetoprotein levels in patients with chronic hepatitis CC W Chu
Department of Medicine, Veterans General Hospital-Taipei and National Yang-Ming University School of Medicine, Taiwan, Republic of China
J Clin Gastroenterol 32:240-4. 2001..In conclusion, elevated serum AFP levels were significantly correlated with lower serum albumin levels, advanced fibrosis/cirrhosis, and genotype 1b infection in patients with chronic hepatitis C... - Electrogastrographic characteristics in patients of stomach cancerF Y Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine, National Yang Ming University, Taiwan
Dig Dis Sci 46:1458-65. 2001..We conclude that apparent arrhythmia is not encountered in GC patients, although they mainly exhibit obvious postprandial power response. Advanced GC is likely responsible for this power enhancement on EGG recording... - Kidney transplantation in patients with chronic hepatitis B virus infection: is the prognosis worse?T I Huo
Department of Medicine, Taipei Veterans General Hospital, Taiwan
Dig Dis Sci 46:469-75. 2001..In conclusion, HBV infection is not a contraindication to kidney transplantation. However, pretransplant candidates should be warned of potentially serious liver-related complications... - Unchanging trend of adenocarcinoma of the esophagus and gastric cardia in Taiwan: a 15-year experience in a single centerShen-Shong Chang
Division of Gastroenterology, Cancer Center, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taiwan
Dig Dis Sci 47:735-40. 2002..Although gastroesophageal reflux disease is common here, its definite pathogenesis leading to esophageal adenocarcinoma or gastric cardia carcinoma remains unresolved... - Rapid urinary trypsinogen-2 test strip in the diagnosis of acute pancreatitisYen-Ting Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
Pancreas 30:243-7. 2005..A positive test identifies patients in need of further diagnostic measures. The urinary trypsinogen-2 test can be performed in health care units where laboratory testing facilities are not immediately available... - Simvastatin for rats with thioacetamide-induced liver failure and encephalopathyHui Chun Huang
Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 23:e236-42. 2008..The aim of this study was to assess the effects of simvastatin on rats with TAA-induced acute liver damage and hepatic encephalopathy... - Hepatitis C viral genotype influences the clinical outcome of patients with acute posttransfusion hepatitis CS J Hwang
Department of Family Medicine, Veterans General Hospital-Taipei, National Yang-Ming University School of Medicine, 201 Shih-Pai Road, Section 2, Taipei, 11217, Taiwan, Republic of China
J Med Virol 65:505-9. 2001..Therefore, the HCV genotype can influence the outcome of patients with acute HCV infection... - Plasma erythropoietin level in patients with cirrhosis and its relationship to the severity of cirrhosis and renal functionYing Ying Yang
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, and Institute of Traditional Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
J Gastroenterol Hepatol 18:1156-61. 2003..In contrast, the EPO levels had no correlation to the nitrate/nitrite levels and systemic vascular resistance in patients with cirrhosis... - Risk of hepatic failure after transcatheter arterial chemoembolization for hepatocellular carcinoma: predictive value of the monoethylglycinexylidide testYi-Shin Huang
Department of Medicine, Taipei Veterans General Hospital, Taiwan
Am J Gastroenterol 97:1223-7. 2002..The monoethylglycinexylidide test may be used to select patients with relatively good liver reserves for safe TACE treatment... - Stomach myoelectrical response of patients with gastroesophageal reflux disease receiving omeprazole treatmentFull-Young Chang
Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine National Yang Ming University, and Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
J Gastroenterol Hepatol 18:1399-406. 2003..Effective omeprazole treatment only improves the postprandial myoelectrical regularity, whereas abnormal EGG parameters remain impaired... - Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinomaYi Shin Huang
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang Ming University School of Medicine, Taipei, Taiwan
Am J Gastroenterol 98:1417-22. 2003..The aim of this study was to evaluate the relationship of NAT2 genetic polymorphisms with hepatocellular carcinoma (HCC), with special reference to the interaction of dietary habits... - The effect of H2-receptor antagonist and proton pump inhibitor on microbial proliferation in the stomachKun Wang
Division of Gastroenterology, Department of Medicine, Cardinal Tien Hospital and School of Medicine Fu-Jen Catholic University, Taipei, Taiwan, ROC
Hepatogastroenterology 51:1540-3. 2004..The intra-gastric candidal infection was not related to intra-gastric pH or anti-secretory medication in this study... - Social and medical impact, sleep quality and the pharmaceutical costs of heartburn in TaiwanC L Lu
Division of Gastroenterology, Taipei Veterans General Hospital, and School of Medicine, National Yang Ming University, Taipei, Taiwan
Aliment Pharmacol Ther 22:739-47. 2005..Little is known about the social and medical burdens of heartburn in Asia... - Hemodynamic effects of a combination of octreotide and terlipressin in patients with viral hepatitis related cirrhosisH C Lin
Dept of Medicine, Taipei Veterans General Hospital and School of Medicine and Tih Wu Liver Research Center, National Yang Ming University, Taiwan
Scand J Gastroenterol 37:482-7. 2002..The current study was aimed at evaluating such a combination treatment in patients with cirrhosis and portal hypertension... - Correlation of interleukin-10 gene haplotype with hepatocellular carcinoma in TaiwanL H Tseng
Department of Medical Genetics and Internal Medicine, National Taiwan University Hospital, and Graduate Institutes of Clinical Medicine, National Taiwan University, Taipei, Taiwan
Tissue Antigens 67:127-33. 2006..6, 95% CI: 1.3-4.9). The results demonstrate that IL-10 gene polymorphism can affect the outcome of chronic HBV infection. Further studies are necessary to clarify how variation in the IL-10 gene affects IL-10 function and risk of HCC... - Impacts of peripheral obestatin on colonic motility and secretion in conscious fed ratsC Y Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Peptides 29:1603-8. 2008..In conclusion, peripheral obestatin administration has no impact on colonic motility and secretion in conscious fed rats... - Extending the reading time increases the accuracy of rapid whole blood test for diagnosis of Helicobacter pylori infectionT S Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, and National Yang Ming University, Taipei, Taiwan, Republic of China
J Gastroenterol Hepatol 16:1341-5. 2001..To evaluate the accuracy of two rapid whole blood tests (the BM-Test Helicobacter pylori and the QuikPac IV One Step H. pylori Whole Blood Test), and compare this to a conventional quantitative ELISA test (HEL-p TEST II)... - Long-term outcome of kidney transplantation in patients with hepatitis C virus infectionT I Huo
Organ Transplant Unit, Department of Medicine, Taipei Veterans General Hospital, Taiwan Republic of China
Hepatogastroenterology 48:169-73. 2001..The impact of HCV (hepatitis C virus) infection on the long-term outcome of kidney transplant patients is controversial... - Comparison of percutaneous acetic acid injection and percutaneous ethanol injection for hepatocellular carcinoma in cirrhotic patients: a prospective studyT I Huo
Division of Gastroenterology, Dept of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Scand J Gastroenterol 38:770-8. 2003..We conducted a prospective study to compare the therapeutic efficacy of both these methods... - The clinical significance of hyperamylasemia in organophosphate poisoningW C Lee
Veterans General Hospital Taipei and School of Medicine, National Yang Ming University, Taiwan
J Toxicol Clin Toxicol 36:673-81. 1998..Hyperamylasemia with a presumptive diagnosis of acute pancreatitis has been reported following organophosphate poisoning but there are no large-scale studies incorporating more specific diagnostic criteria... - Plasma levels of interleukin-6 and interleukin-8 in Chinese patients with non-alcoholic fatty liver diseaseChi Jen Chu
Division of Gastroenterology, Department of Medicine Taipei Veterans General Hospital, Taipei, Taiwan 11217, Republic of China
Hepatogastroenterology 54:2045-8. 2007..There has been no report regarding plasma levels of IL-6 and Il-8 in Chinese patients with NAFLD... - Smoking and hyperpepsinogenemia are associated with increased risk for duodenal ulcer in Helicobacter pylori-infected patientsTseng Shing Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, and National Yang Ming University, Taipei, Taiwan, R O C
J Clin Gastroenterol 39:699-703. 2005..pylori causes different gastroduodenal diseases in different people is at present not clear... - Health-related quality of life and impact of antiviral treatment in Chinese patients with chronic hepatitis C in TaiwanShih-Chao Kang
Division of Family Medicine, I-Lan Hospital, Taiwan, China
World J Gastroenterol 11:7494-8. 2005..Antiviral treatment impaired HRQOL of CH-C subjects during early treatment, mainly in non-sustained virological responders, and improved at mo 6 after stopping the treatment, mainly in sustained virological responders... - HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell linesKeng Hsin Lan
Division of Gastroenterology, Department of Medicine, National Yang Ming University, Taipei, Taiwan
J Hepatol 46:759-67. 2007..Most studies regarding the involvement of signal transducer and activator of transcription 1 (STAT1) in inhibition of IFN-alpha signaling by NS5A were performed in non-hepatic cell lines and their relevance may be debatable... - Irritable bowel syndrome and negative appendectomy: a prospective multivariable investigationChing Liang Lu
Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine, National Yang Ming University, Taipei, Taiwan 11217
Gut 56:655-60. 2007..To examine prospectively whether irritable bowel syndrome (IBS) or other variables-that is, psychiatric profiles, health-related quality of life (HRQoL) and clinical features-are associated with negative appendectomy (NA)... - Different model for end-stage liver disease score block distributions may have a variable ability for outcome predictionTeh Ia Huo
National Yang Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Transplantation 80:1414-8. 2005..However, it is not clear if the predictive accuracy of MELD is equally homogeneous in different distribution of MELD score blocks... - Proposal of a modified Child-Turcotte-Pugh scoring system and comparison with the model for end-stage liver disease for outcome prediction in patients with cirrhosisTeh Ia Huo
National Yang Ming University School of Medicine, Taipei, Taiwan, Republic of China
Liver Transpl 12:65-71. 2006..By extending the score range according to the influence of the laboratory-derived variables, the modified CTP system has a better performance than the original system and is as efficient as the MELD for outcome prediction... - Psychosocial distress is associated with abnormal gastric myoelectrical activity in patients with functional dyspepsiaTseng Shing Chen
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201 Section 2 Shih Pai Road, Taipei, Taiwan 11217
Scand J Gastroenterol 41:791-6. 2006.... - Estrogen rapidly modulates mustard oil-induced visceral hypersensitivity in conscious female rats: A role of CREB phosphorylation in spinal dorsal horn neuronsChing Liang Lu
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201, Sec 2, Shih Pai Rd, Taipei, Taiwan 11217
Am J Physiol Gastrointest Liver Physiol 292:G438-46. 2007.... - Fever and infectious complications after percutaneous acetic acid injection therapy for hepatocellular carcinoma: incidence and risk factor analysisTeh Ia Huo
Institute of Pharmacology and Faculty of Medicine, National Yang Ming University School of Medicine Departments of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
J Clin Gastroenterol 40:639-42. 2006..Posttreatment fever (>37.5 degrees C) may occur owing to acetic acid-induced tumor necrosis, but its incidence and clinical significance are not clear...