Jin Ching Lin

Summary

Affiliation: Taichung Veterans General Hospital
Country: Taiwan

Publications

  1. ncbi request reprint Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital Taiwan, No 160, Sec 3, Taichung Kang Road, Taichung, 407 Taiwan
    J Clin Oncol 21:631-7. 2003
  2. pmc Outpatient weekly neoadjuvant chemotherapy followed by radiotherapy for advanced nasopharyngeal carcinoma: high complete response and low toxicity rates
    J C Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taiwan
    Br J Cancer 88:187-94. 2003
  3. ncbi request reprint Outpatient weekly 24-hour infusional adjuvant chemotherapy of cisplatin, 5-fluorouracil, and leucovorin for high-risk nasopharyngeal carcinoma
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, No 160, Sec 3, Taichung Kang Rd, Taichung, 407, Taiwan
    Head Neck 25:438-50. 2003
  4. ncbi request reprint Socio-demographic factors in the prognosis of oral cancer patients
    Yong Kie Wong
    Department of Oral and Maxillofacial Surgery, Taichung Veterans General Hospital, Taichung, Taiwan
    Oral Oncol 42:893-906. 2006
  5. ncbi request reprint Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    N Engl J Med 350:2461-70. 2004
  6. ncbi request reprint Endoscopic sinus surgery for the treatment of chronic rhinosinusitis in patients with postirradiated nasopharyngeal carcinoma
    Mao chang Su
    Department of Otolaryngology, Chung Shan Medical University Hospital, Taichung, Taiwan
    Am J Otolaryngol 27:46-9. 2006
  7. doi request reprint The volume of retropharyngeal nodes predicts distant metastasis in patients with advanced nasopharyngeal carcinoma
    Kuan Wen Chen
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    Oral Oncol 47:1171-5. 2011
  8. doi request reprint Long-term result of management of otitis media with effusion in patients with post-irradiated nasopharyngeal carcinoma
    Kai Li Liang
    Department of Otolaryngology, Taichung Veterans General Hospital, No 160, Chung Kang Road, Section 3, Taichung 407, Taiwan
    Eur Arch Otorhinolaryngol 268:213-7. 2011
  9. doi request reprint Long-term survival analysis of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA levels
    Wen yi Wang
    Section of Basic Medicine, Department of Nursing, Hung Kuang University, Taichung, Taiwan
    Cancer 119:963-70. 2013
  10. ncbi request reprint Consistent sequence variation of Epstein-Barr virus nuclear antigen 1 in primary tumor and peripheral blood cells of patients with nasopharyngeal carcinoma
    Wen yi Wang
    Department of Basic Medicine, Hung Kuang Institute of Technology, Taichung, Taiwan
    Clin Cancer Res 8:2586-90. 2002

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital Taiwan, No 160, Sec 3, Taichung Kang Road, Taichung, 407 Taiwan
    J Clin Oncol 21:631-7. 2003
    ..Nasopharyngeal carcinoma (NPC) is a radiosensitive and chemosensitive tumor. This randomized phase III trial compared concurrent chemoradiotherapy (CCRT) versus radiotherapy (RT) alone in patients with advanced NPC...
  2. pmc Outpatient weekly neoadjuvant chemotherapy followed by radiotherapy for advanced nasopharyngeal carcinoma: high complete response and low toxicity rates
    J C Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taiwan
    Br J Cancer 88:187-94. 2003
    ..0, 92.1, and 77.5%, respectively. Preliminary data of the current study show that P-FL NeoCT plus radiotherapy is a low-toxic regimen with promising results on very advanced NPC patients and merits to be investigated in phase III trials...
  3. ncbi request reprint Outpatient weekly 24-hour infusional adjuvant chemotherapy of cisplatin, 5-fluorouracil, and leucovorin for high-risk nasopharyngeal carcinoma
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, No 160, Sec 3, Taichung Kang Rd, Taichung, 407, Taiwan
    Head Neck 25:438-50. 2003
    ..The aim of this study is to evaluate the toxicity and survival of outpatient weekly 24-hour infusion adjuvant chemotherapy for NPC patients with high-risk of distant failure...
  4. ncbi request reprint Socio-demographic factors in the prognosis of oral cancer patients
    Yong Kie Wong
    Department of Oral and Maxillofacial Surgery, Taichung Veterans General Hospital, Taichung, Taiwan
    Oral Oncol 42:893-906. 2006
    ..Therefore, care providers should take socio-demographic issues into consideration aside from ordinary clinical health care...
  5. ncbi request reprint Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    N Engl J Med 350:2461-70. 2004
    ..We investigated the clinical significance of plasma concentrations of Epstein-Barr virus (EBV) DNA in patients with advanced nasopharyngeal carcinoma...
  6. ncbi request reprint Endoscopic sinus surgery for the treatment of chronic rhinosinusitis in patients with postirradiated nasopharyngeal carcinoma
    Mao chang Su
    Department of Otolaryngology, Chung Shan Medical University Hospital, Taichung, Taiwan
    Am J Otolaryngol 27:46-9. 2006
    ..Our purpose was to evaluate the efficacy and safety of endoscopic sinus surgery (ESS) in patients with nasopharyngeal carcinoma (NPC) after irradiation...
  7. doi request reprint The volume of retropharyngeal nodes predicts distant metastasis in patients with advanced nasopharyngeal carcinoma
    Kuan Wen Chen
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    Oral Oncol 47:1171-5. 2011
    ..001), gender (P=0.026), and RNV (P=0.088) were important predictors for DMFFS. We conclude that the RNV measured by MRI is a potential predictor of distant metastasis in patients with advanced NPC...
  8. doi request reprint Long-term result of management of otitis media with effusion in patients with post-irradiated nasopharyngeal carcinoma
    Kai Li Liang
    Department of Otolaryngology, Taichung Veterans General Hospital, No 160, Chung Kang Road, Section 3, Taichung 407, Taiwan
    Eur Arch Otorhinolaryngol 268:213-7. 2011
    ..Only 15 (17.6%) were free of OME, and one patient had a dry perforated eardrum. Our results showed current methods did not result in long-term resolution of some recalcitrant post-irradiated OME...
  9. doi request reprint Long-term survival analysis of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA levels
    Wen yi Wang
    Section of Basic Medicine, Department of Nursing, Hung Kuang University, Taichung, Taiwan
    Cancer 119:963-70. 2013
    ..The objective of this study was to confirm the relation between plasma Epstein-Barr virus (EBV) DNA (pEBV DNA) load and treatment outcomes after long-term follow-up in patients with nasopharyngeal carcinoma (NPC)...
  10. ncbi request reprint Consistent sequence variation of Epstein-Barr virus nuclear antigen 1 in primary tumor and peripheral blood cells of patients with nasopharyngeal carcinoma
    Wen yi Wang
    Department of Basic Medicine, Hung Kuang Institute of Technology, Taichung, Taiwan
    Clin Cancer Res 8:2586-90. 2002
    ..This study was performed to examine sequence variations of the EBV nuclear antigen 1 gene (EBNA-1) in primary tumor and peripheral-blood cells of NPC patients from Taiwan...
  11. ncbi request reprint Long-term prognostic effects of plasma epstein-barr virus DNA by minor groove binder-probe real-time quantitative PCR on nasopharyngeal carcinoma patients receiving concurrent chemoradiotherapy
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
    Int J Radiat Oncol Biol Phys 68:1342-8. 2007
    ....
  12. doi request reprint Plasma Epstein-Barr virus DNA screening followed by ¹⁸F-fluoro-2-deoxy-D-glucose positron emission tomography in detecting posttreatment failures of nasopharyngeal carcinoma
    Wen yi Wang
    Section of Basic Medicine, Department of Nursing, Hung Kuang University, Taichung, Taiwan
    Cancer 117:4452-9. 2011
    ..The authors investigated the clinical implication of plasma Epstein-Barr virus (EBV) DNA assay and (18) F-fluoro-2-deoxy-D-glucose ((18) F-FDG) positron emission tomography (PET) in the detection of recurrent nasopharyngeal carcinoma (NPC)...
  13. ncbi request reprint Another way to estimate outcome of advanced nasopharyngeal carcinoma--is concurrent chemoradiotherapy adequate?
    Jin Ching Lin
    Department of Radiation Oncology, Taichung Veterans General Hospital, No 160 Section 3 Taichung Kang Road, Taichung 407, Taiwan
    Int J Radiat Oncol Biol Phys 60:156-64. 2004
    ..To evaluate a simple risk grouping system and determine whether concurrent chemoradiotherapy (CCRT) is adequate for patients with advanced nasopharyngeal carcinoma (NPC)...
  14. doi request reprint Nasal irrigation reduces postirradiation rhinosinusitis in patients with nasopharyngeal carcinoma
    Kai Li Liang
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Am J Rhinol 22:258-62. 2008
    ..The purpose of this study was to determine the IMRT effect on the paranasal sinuses and evaluate the efficacy of nasal irrigation on the management of RT-induced rhinosinusitis...
  15. doi request reprint Effects of KRAS mutation and polymorphism on the risk and prognosis of oral squamous cell carcinoma
    Wen yi Wang
    Section of Basic Medicine, Department of Nursing, Hung Kuang University, Taichung, Taiwan
    Head Neck 34:663-6. 2012
    ..The purpose of this study was to analyze whether the KRAS polymorphisms and mutations can be useful prognostic or risk markers in oral squamous cell carcinoma (OSCC)...
  16. doi request reprint Definitive intensity-modulated radiation therapy with concurrent chemotherapy for patients with locally advanced cervical cancer
    Chien Chih Chen
    Department of Radiation Oncology, Taichung Veterans General Hospital, Taiwan, ROC
    Gynecol Oncol 122:9-13. 2011
    ....
  17. doi request reprint Surgical site infection after preoperative neoadjuvant chemotherapy in patients with locally advanced oral squamous cell carcinoma
    Shih An Liu
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Head Neck 33:954-8. 2011
    ..We investigated whether preoperative neoadjuvant chemotherapy is associated with increased surgical site infection (SSI) rate in patients with locally advanced oral cancer...
  18. ncbi request reprint Nutritional factors and survival of patients with oral cancer
    Shih An Liu
    Department of Otolaryngology, Taichung Veterans General Hospital, No 160, Section 3, Taichung Harbor Road, Taichung 40705, Taiwan
    Head Neck 28:998-1007. 2006
    ..Our objective was to determine the survival rate of patients with oral cancer who were treated at a medical center in central Taiwan. Furthermore, we attempted to investigate whether nutritional factors influence the survival...
  19. ncbi request reprint Experience in fractionated stereotactic body radiation therapy boost for newly diagnosed nasopharyngeal carcinoma
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 66:1408-14. 2006
    ..Radiotherapy is the most effective treatment for nasopharyngeal carcinoma (NPC). The aim of this study is to evaluate the efficacy and toxicity of fractionated stereotactic body radiation therapy (SBRT) boost for NPC...
  20. doi request reprint A preliminary study on the role of inherited prothrombotic risk factors in Taiwanese patients with sudden sensorineural hearing loss
    Ming Ying Lan
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC
    Eur Arch Otorhinolaryngol 268:817-22. 2011
    ..Further studies with a large series of patients are needed to identify other possible candidate genes in order to elucidate the pathogenesis of SSHL...
  21. ncbi request reprint Impact of recurrence interval on survival of oral cavity squamous cell carcinoma patients after local relapse
    Shih An Liu
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Otolaryngol Head Neck Surg 136:112-8. 2007
    ..The aim of this study was to investigate whether the recurrence interval influenced the survival of oral cavity squamous cell carcinoma patients after relapse...
  22. doi request reprint Central nervous system infection in patients with postirradiated nasopharyngeal carcinoma: a case-controlled study
    Kai Li Liang
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Am J Rhinol Allergy 23:417-21. 2009
    ..It has been assumed that postirradiated nasopharyngeal carcinoma (NPC) patients are prone to central nervous system (CNS) infection...
  23. doi request reprint Somatic mutations in the D-loop of mitochondrial DNA in oral squamous cell carcinoma
    Shih An Liu
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Eur Arch Otorhinolaryngol 269:1665-70. 2012
    ..4 vs. 45.0%, P = 0.0374). A high rate of somatic mutations in the D-loop region of mtDNA was found in betel quid-related oral squamous cell carcinoma patients. Somatic mutation of D-loop of mtDNA was associated with better survival...
  24. ncbi request reprint PCR detection of circulating tumor cells in nasopharyngeal carcinoma patients with distant metastasis: effect of enzyme and sampling
    Jin Ching Lin
    Institute of Clinical Medicine, College of Medicine, National Yang Ming University, Taipei, Taiwan
    Head Neck 24:591-6. 2002
    ..This study was performed to evaluate the effect of blood sampling and different Taq DNA polymerase on the results of nested reverse transcriptase-polymerase chain reaction (RT-PCR) assay...
  25. ncbi request reprint Evaluation of cytokeratin-19 mRNA as a tumor marker in the peripheral blood of nasopharyngeal carcinoma patients receiving concurrent chemoradiotherapy
    Jin Ching Lin
    Institute of Clinical Medicine, College of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Int J Cancer 97:548-53. 2002
    ..9% for patients with detectable CK-19 and 85.9% for those with undetectable CK-19 (p = 0.0089, log-rank test). Our data suggest that the presence of CK-19 mRNA in the peripheral blood may be a potential marker of micrometastasis for NPC...
  26. ncbi request reprint Nasopharyngeal carcinoma during pregnancy
    Tsung I Lin
    Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, Taiwan
    Taiwan J Obstet Gynecol 46:423-6. 2007
    ..Nasopharyngeal carcinoma, particularly during pregnancy, rarely comes to medical attention before it spreads to the regional lymph nodes...
  27. ncbi request reprint Assessment of salivary function change in nasopharyngeal carcinoma treated by parotid-sparing radiotherapy
    Wen Shan Liu
    Department of Radiation Oncology, Chung Shan Medical University, Taichung Veterans General Hospital, Taiwan
    Cancer J 12:494-500. 2006
    ..The purpose of this study was to evaluate function of major salivary glands, subjective xerostomia, and correlation between subjective and objective xerostomia scoring after precision-oriented radiotherapy for nasopharyngeal carcinoma...
  28. doi request reprint Induction of apoptosis by high-dose gold nanoparticles in nasopharyngeal carcinoma cells
    Ming Ying Lan
    Department of Otolaryngology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, ROC
    Auris Nasus Larynx 40:563-8. 2013
    ..However, their role on nasopharyngeal cancer remains unknown. The object of this study is to investigate if AuNPs can be used as a new therapeutic agent for NPC by evaluating their anti-tumor effect in vitro...
  29. ncbi request reprint A novel p53 mutant retained functional activity in lung carcinomas
    Jiunn Liang Ko
    Institute of Toxicology, Chung Shan Medical University, Taichung, Taiwan, ROC
    DNA Repair (Amst) 1:755-62. 2002
    ..Therefore, mutant p53 alone is an insufficient indicator of poor prognosis. Instead, functional p53 may affect lung cancer prognosis...
  30. doi request reprint From NPC therapeutic target identification to potential treatment strategy
    Ming Ying Lan
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Mol Cancer Ther 9:2511-23. 2010
    ..109.23.188:8080/NPC) was established to facilitate future NPC research. This in silico approach, from target prioritization to potential drugs identification, might be an effective method for various cancer researches...
  31. ncbi request reprint Comparison of the prognostic impact of serum anti-EBV antibody and plasma EBV DNA assays in nasopharyngeal carcinoma
    Chih Wen Twu
    Institute of Clinical Medicine, School of Medicine, National Yang Ming University, Taipei
    Int J Radiat Oncol Biol Phys 67:130-7. 2007
    ..Serum anti-EBV antibodies and plasma EBV DNA have been investigated as surrogate markers for NPC. A comparison of the prognostic impacts of both assays has never been reported...
  32. ncbi request reprint Association of p53 codon 72 polymorphism with risk of hypopharyngeal squamous cell carcinoma in Taiwan
    Chih Wen Twu
    Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, ROC
    J Formos Med Assoc 105:99-104. 2006
    ..This study investigated the genotype distribution of p53 codon 72 polymorphism in hypopharyngeal cancer patients and non-cancer controls matched for age, gender, alcohol consumption and smoking habit...
  33. ncbi request reprint Mitochondrial genome instability and mtDNA depletion in human cancers
    Hsin Chen Lee
    Department of Pharmacology, School of Medicine, National Yang Ming University, Taipei, Taiwan 112, Republic of China
    Ann N Y Acad Sci 1042:109-22. 2005
    ..Taken together, our findings suggest that instability in the D-loop region of mtDNA, together with the decrease in mtDNA copy number, is involved in the carcinogenesis of human cancers...
  34. ncbi request reprint Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
    Hsin Chen Lee
    Institute of Biochemistry, Chung Shan Medical University, Taichung 402, Taiwan, ROC
    Mutat Res 547:71-8. 2004
    ..The results obtained in this study strongly suggest that somatic mutations in the D-loop together with the decrease in the copy number of mtDNA may be an important event during the early phase of liver carcinogenesis...
  35. doi request reprint Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region
    Wen Yi Hung
    Department and Institute of Pharmacology, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Mutagenesis 23:137-42. 2008
    ..These observations suggest that the occurrence of the tandem duplication/triplication in mtDNA D-loop is not specific for cancer tissues, but highly associated with the poly-C length variations around np 568...