Research Topics
Species | H M HuangSummaryAffiliation: Taichung Veterans General Hospital Country: Taiwan Publications
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Detail Information
Publications
Amyloid beta peptide enhanced bradykinin-mediated inositol (1,4,5)trisphosphate formation and cytosolic free calciumH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taiwan, ROC
Life Sci 63:195-203. 1998..Changes in the balance of these receptor-mediated signals prior to cell injury could be an important underlying mechanism for A beta peptide-induced degenerative alteration in AD...
Selective subcellular redistributions of protein kinase C isoforms by chemical hypoxiaH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taiwan, Republic of China
J Neurosci Res 56:668-78. 1999..Taking the results together, differential activation/translocation of PKC isozymes by KCN and TPA is important in the regulation of chemical hypoxia-induced cell injury in PC12 cells...
Amyloid beta peptide impaired carbachol but not glutamate-mediated phosphoinositide pathways in cultured rat cortical neuronsH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taiwan, ROC
Neurochem Res 25:303-12. 2000..Because functional loss of cholinergic pathways is an important aspect of AD, the differences in susceptibility of these two types of receptors prior to other signs of A(beta) action is important and requires further investigation...
Blockage of amyloid beta peptide-induced cytosolic free calcium by fullerenol-1, carboxylate C60 in PC12 cellsH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taiwan, ROC
Life Sci 66:1525-33. 2000..Furthermore, fullerenol-1, a novel antioxidant, may provide therapeutic benefits in neurodegenerative diseases such as AD...
Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neuronsH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taiwan, ROC
Life Sci 66:1879-92. 2000..In addition, antioxidants such as B27 were effective in protecting cultured cortical neurons against (A)beta, and correlated with (A)beta attenuation of early calcium response...
Anti-inflammatory and neuroprotective effects of magnolol in chemical hypoxia in rat cultured cortical cells in hypoglycemic mediaM M Lee
Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
Chin J Physiol 43:61-7. 2000..These findings suggest that the protective effects of magnolol against brain damage by KCN or KCN plus LPS in hypoglycemic media may involve inhibition of PGE2 production, but inhibition of NO generation may not be important...
Determination of catecholamines in pheochromocytoma cell (PC-12) culture medium by microdialysis-microbore liquid chromatographyF C Cheng
Department of Medical Research, Taichung Veterans General Hospital, Taiwan
J Chromatogr A 870:405-11. 2000..5 mM potassium cyanide. In conclusion, the present microassay provides for the sensitive, direct measurement of catecholamines in culture medium while minimizing pretreatment procedures for sample preparation...
Apolipoprotein E polymorphism in various dementias in Taiwan Chinese populationH M Huang
Department of Education and Medical Research, Taichung Veterans General Hospital, Taichung
J Neural Transm 109:1415-21. 2002..The lack of association between VD and APOE4 allele frequency suggests that APOE4 allele does not associate with cerebrovascular pathology related dementia in Taiwan Chinese...
