Yu Sun

Summary

Country: Taiwan

Publications

  1. ncbi request reprint Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion
    Yu Sun
    Division of Molecular Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Biol Chem 278:27688-94. 2003
  2. ncbi request reprint Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, San Shia, Taipei, Taiwan
    Clin Ther 29:2204-14. 2007
  3. ncbi request reprint Carotid atherosclerosis, intima media thickness and risk factors--an analysis of 1781 asymptomatic subjects in Taiwan
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, Taipei County, San shia Town, Taiwan
    Atherosclerosis 164:89-94. 2002
  4. ncbi request reprint Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trials
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, San Shia, Taipei, Taiwan
    Acta Neurol Taiwan 14:48-54. 2005
  5. pmc Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease
    Hui Chi Cheng
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    J Negat Results Biomed 11:5. 2012
  6. ncbi request reprint Postprocedural complications after angioplasty with stenting of the internal carotid artery
    Chien Jung Lu
    Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan
    Cerebrovasc Dis 16:308-10. 2003
  7. pmc Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease
    Yen Ching Chen
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    PLoS ONE 7:e50771. 2012
  8. pmc Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease
    Shih Yuan Chen
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    J Neuroinflammation 9:21. 2012
  9. pmc CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease
    Pei Hsuan Weng
    Department of Family Medicine, Taiwan Adventist Hospital, Taipei, Taiwan Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    PLoS ONE 8:e84059. 2013
  10. doi request reprint Lack of association between total serum homocysteine and extracranial cerebral flow
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    J Formos Med Assoc 109:278-86. 2010

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion
    Yu Sun
    Division of Molecular Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Biol Chem 278:27688-94. 2003
    ..LXR and ABCA1-induced changes in membrane lipid organization had favorable effects on processing of APP, suggesting a new approach to the treatment of Alzheimer's disease...
  2. ncbi request reprint Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, San Shia, Taipei, Taiwan
    Clin Ther 29:2204-14. 2007
    ..5 mg with an active methyl base, and an over-the-counter nutritional supplement that contains folic acid 1 mg and pyridoxine hyperchloride 5 mg may be effective as a homocysteine-lowering vitamin regimen...
  3. ncbi request reprint Carotid atherosclerosis, intima media thickness and risk factors--an analysis of 1781 asymptomatic subjects in Taiwan
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, Taipei County, San shia Town, Taiwan
    Atherosclerosis 164:89-94. 2002
    ..68 mm correlated with obviously increased risk of carotid atherosclerosis. Age, systolic blood pressure and fasting blood sugar were independent risk factors related to both carotid atherosclerosis and thick IMT...
  4. ncbi request reprint Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trials
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, San Shia, Taipei, Taiwan
    Acta Neurol Taiwan 14:48-54. 2005
    ..However, more high-quality, double-blind randomized controlled trials are needed to confirm the effects of vitamin B12 on diabetic neuropathy...
  5. pmc Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease
    Hui Chi Cheng
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    J Negat Results Biomed 11:5. 2012
    ..Only one study has investigated the association between NGFR polymorphisms and the risk of AD in an Italian population. Type 2 diabetes mellitus (DM) may modify this association based on previous animal and epidemiologic studies...
  6. ncbi request reprint Postprocedural complications after angioplasty with stenting of the internal carotid artery
    Chien Jung Lu
    Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan
    Cerebrovasc Dis 16:308-10. 2003
  7. pmc Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease
    Yen Ching Chen
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    PLoS ONE 7:e50771. 2012
    ..No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD risk previously and ApoE e4 status alone showed low sensitivity in identifying late-onset AD (LOAD) patients...
  8. pmc Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease
    Shih Yuan Chen
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    J Neuroinflammation 9:21. 2012
    ..However, previous studies relating IL-6 genetic polymorphisms to AD included few and unrepresentative single nucleotide polymorphisms (SNPs) and the results were inconsistent...
  9. pmc CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease
    Pei Hsuan Weng
    Department of Family Medicine, Taiwan Adventist Hospital, Taipei, Taiwan Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    PLoS ONE 8:e84059. 2013
    ..Previously, CHRNA7 polymorphisms have not been related to cholinesterase inhibitors (ChEI) response...
  10. doi request reprint Lack of association between total serum homocysteine and extracranial cerebral flow
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    J Formos Med Assoc 109:278-86. 2010
    ..High homocysteine (Hcy) concentration is associated with slow coronary flow. This study examined the association between Hcy and hemodynamic status in the extracranial cerebral arteries in healthy individuals...
  11. doi request reprint Prediction of infarct growth and neurologic deterioration in patients with positive perfusion-diffusion mismatch
    Chien Tai Hong
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    Clin Neurol Neurosurg 114:376-80. 2012
    ..To assess the value of baseline clinical severity and perfusion-diffusion mismatch as predictors for further infarct growth and clinical outcome...
  12. doi request reprint Risk of stroke with thiazolidinediones: a ten-year nationwide population-based cohort study
    Chien Jung Lu
    Department of Neurology, En Chu Kong Hospital, National Taiwan University, New Taipei City, Taiwan
    Cerebrovasc Dis 36:145-51. 2013
    ..Most of the studies on cardiovascular effects of TZDs were based on studies in the USA and Europe. The present study aimed to compare the stroke risk among diabetic patients on TZD to those on non-TZD medications in an Asian population...
  13. ncbi request reprint Use of serum homocysteine to predict stroke, coronary heart disease and death in ethnic Chinese. 12-year prospective cohort study
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    Circ J 73:1423-30. 2009
    ..Prospective data about the association between serum total homocysteine (Hcy) and vascular disease in Asia is limited because few investigations have evaluated the cutpoint of Hcy for predicting the risk of vascular disease and death...
  14. doi request reprint Madelung's disease associated with polyneuropathy and symptomatic hypokalemia
    Hoi Fong Chan
    Department of Neurology, En Chu Kong Hospital, Taipei County, Taiwan
    J Formos Med Assoc 112:283-6. 2013
    ..Proximal weakness improved with potassium supplement. Our observation may extend the phenotype of Madelung's disease to hypokalemic periodic paralysis...
  15. doi request reprint Incidence of Creutzfeldt-Jakob disease in Taiwan: a prospective 10-year surveillance
    Chien Jung Lu
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    Eur J Epidemiol 25:341-7. 2010
    ..Our data showed low annual incidence rate and high frequency of methionine homozygous prion protein genotype of sCJD in Taiwan. This report provided important epidemiological data on ethnic Chinese...
  16. pmc Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's disease
    Kun Pei Lin
    Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    PLoS ONE 6:e20573. 2011
    ..This study investigated the association between genetic polymorphisms of a vascular susceptibility gene, Ninjurin2 (NINJ2), and the risk of dementia, which has not been explored previously...
  17. pmc A nationwide survey of mild cognitive impairment and dementia, including very mild dementia, in taiwan
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, New Taipei City, Taiwan Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    PLoS ONE 9:e100303. 2014
    ..The inclusion of VMD yields dementia prevalence rates higher than those previously reported from Taiwan. Old age, female gender, and a low educational level are significant associated factors. ..
  18. ncbi request reprint Fatal intoxication using amantadine and pramipexole in a uremic patient
    Chien Tai Hong
    Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
    Acta Neurol Taiwan 17:109-11. 2008
    ..Toxic manifestation includes myoclonus, ataxia, confusion and sudden death. This report highlights the fact that using amantadine and pramipexole may be fatal in patients with uremia even undergoing hemodialysis...
  19. doi request reprint Get With the Guidelines-Stroke performance indicators: surveillance of stroke care in the Taiwan Stroke Registry: Get With the Guidelines-Stroke in Taiwan
    Fang I Hsieh
    School of Public Health, Taipei Medical University, Taipei, Taiwan
    Circulation 122:1116-23. 2010
    ....
  20. pmc Risk of Parkinson disease onset in patients with diabetes: a 9-year population-based cohort study with age and sex stratifications
    Yu Sun
    Department of Neurology, En Chu Kong Hospital, Sanxia District, New Taipei City, Taiwan
    Diabetes Care 35:1047-9. 2012
    ..We retrospectively assessed the age- and sex-specific incidence and relative risk of Parkinson disease (PD) in Taiwan's diabetic population...
  21. ncbi request reprint The hemodynamic effects of internal carotid artery stenting: a study with color-coded duplex sonography
    Chien Jung Lu
    Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan, ROC
    Cerebrovasc Dis 15:264-9. 2003
    ..Color-coded duplex sonography (CDS) is able to measure not only the prestenting stenosis but also the poststenting hemodynamic changes. The purpose of this study was to quantify, using CDS, the hemodynamic changes after ICA stenting...
  22. ncbi request reprint [Effects of Yunnan Baiyao on peri-operative bleeding of patients undergoing cervical open-door laminoplasty: a multi-center randomized double-blind placebo-control trial]
    Sheng Fa Pan
    Department of Orthopedics, Third Hospital of Peking University, Beijing 100083, China
    Zhonghua Yi Xue Za Zhi 86:1888-90. 2006
    ..To investigate the effects of Yunnan Baiyao on peri-operative bleeding of the patients undergoing cervical open-door laminoplasty...
  23. ncbi request reprint Risk factors for pre-eclampsia in pregnant Chinese women with abnormal glucose metabolism
    Yu Sun
    Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
    Int J Gynaecol Obstet 101:74-6. 2008
    ..To investigate the incidence and risk factors for pre-eclampsia in pregnant Chinese women with abnormal glucose metabolism...
  24. ncbi request reprint Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice
    Carrie L Welch
    Columbia University, Department of Medicine, P and S 8 401, 630 W 168th St, New York, NY 10032, USA
    Circulation 116:2444-52. 2007
    ..However, other species are highly resistant to plaque complications, and the specific processes predisposing to plaque destabilization and thrombosis are poorly understood...