Research Topics
Species | Yu SunSummaryCountry: Taiwan Publications
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Detail Information
Publications
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretionYu Sun
Division of Molecular Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J Biol Chem 278:27688-94. 2003..LXR and ABCA1-induced changes in membrane lipid organization had favorable effects on processing of APP, suggesting a new approach to the treatment of Alzheimer's disease...
Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patientsYu Sun
Department of Neurology, En Chu Kong Hospital, San Shia, Taipei, Taiwan
Clin Ther 29:2204-14. 2007..5 mg with an active methyl base, and an over-the-counter nutritional supplement that contains folic acid 1 mg and pyridoxine hyperchloride 5 mg may be effective as a homocysteine-lowering vitamin regimen...
Carotid atherosclerosis, intima media thickness and risk factors--an analysis of 1781 asymptomatic subjects in TaiwanYu Sun
Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, Taipei County, San shia Town, Taiwan
Atherosclerosis 164:89-94. 2002..68 mm correlated with obviously increased risk of carotid atherosclerosis. Age, systolic blood pressure and fasting blood sugar were independent risk factors related to both carotid atherosclerosis and thick IMT...
Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trialsYu Sun
Department of Neurology, En Chu Kong Hospital, No 399, Fuhsin Road, San Shia, Taipei, Taiwan
Acta Neurol Taiwan 14:48-54. 2005..However, more high-quality, double-blind randomized controlled trials are needed to confirm the effects of vitamin B12 on diabetic neuropathy...
Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's diseaseHui Chi Cheng
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
J Negat Results Biomed 11:5. 2012..Only one study has investigated the association between NGFR polymorphisms and the risk of AD in an Italian population. Type 2 diabetes mellitus (DM) may modify this association based on previous animal and epidemiologic studies...
Postprocedural complications after angioplasty with stenting of the internal carotid arteryChien-Jung Lu
Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan
Cerebrovasc Dis 16:308-10. 2003
Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's diseaseShih Yuan Chen
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
J Neuroinflammation 9:21. 2012..However, previous studies relating IL-6 genetic polymorphisms to AD included few and unrepresentative single nucleotide polymorphisms (SNPs) and the results were inconsistent...
Sequence variants of toll like receptor 4 and late-onset Alzheimer's diseaseYen Ching Chen
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan Research Center for Genes, Environment and Human Health, College of Public Health, National Taiwan University, Taipei, Taiwan
PLoS ONE 7:e50771. 2012..No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD risk previously and ApoE e4 status alone showed low sensitivity in identifying late-onset AD (LOAD) patients...
Lack of association between total serum homocysteine and extracranial cerebral flowYu Sun
Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
J Formos Med Assoc 109:278-86. 2010..High homocysteine (Hcy) concentration is associated with slow coronary flow. This study examined the association between Hcy and hemodynamic status in the extracranial cerebral arteries in healthy individuals...
Prediction of infarct growth and neurologic deterioration in patients with positive perfusion-diffusion mismatchChien Tai Hong
Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
Clin Neurol Neurosurg 114:376-80. 2012..To assess the value of baseline clinical severity and perfusion-diffusion mismatch as predictors for further infarct growth and clinical outcome...
Fatal intoxication using amantadine and pramipexole in a uremic patientChien Tai Hong
Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
Acta Neurol Taiwan 17:109-11. 2008..Toxic manifestation includes myoclonus, ataxia, confusion and sudden death. This report highlights the fact that using amantadine and pramipexole may be fatal in patients with uremia even undergoing hemodialysis...
Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's diseaseKun Pei Lin
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
PLoS ONE 6:e20573. 2011..This study investigated the association between genetic polymorphisms of a vascular susceptibility gene, Ninjurin2 (NINJ2), and the risk of dementia, which has not been explored previously...
Incidence of Creutzfeldt-Jakob disease in Taiwan: a prospective 10-year surveillanceChien Jung Lu
Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
Eur J Epidemiol 25:341-7. 2010..Our data showed low annual incidence rate and high frequency of methionine homozygous prion protein genotype of sCJD in Taiwan. This report provided important epidemiological data on ethnic Chinese...
Use of serum homocysteine to predict stroke, coronary heart disease and death in ethnic Chinese. 12-year prospective cohort studyYu Sun
Department of Neurology, En Chu Kong Hospital, Taipei, Taiwan
Circ J 73:1423-30. 2009..Prospective data about the association between serum total homocysteine (Hcy) and vascular disease in Asia is limited because few investigations have evaluated the cutpoint of Hcy for predicting the risk of vascular disease and death...
Risk of Parkinson disease onset in patients with diabetes: a 9-year population-based cohort study with age and sex stratificationsYu Sun
Department of Neurology, En Chu Kong Hospital, Sanxia District, New Taipei City, Taiwan
Diabetes Care 35:1047-9. 2012..We retrospectively assessed the age- and sex-specific incidence and relative risk of Parkinson disease (PD) in Taiwan's diabetic population...
The hemodynamic effects of internal carotid artery stenting: a study with color-coded duplex sonographyChien-Jung Lu
Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan, ROC
Cerebrovasc Dis 15:264-9. 2003..The carotid stenting significantly changed the ICA flow pattern, diameter, residual area, peak systolic velocity and ICA to CCA velocity ratio...
[Effects of Yunnan Baiyao on peri-operative bleeding of patients undergoing cervical open-door laminoplasty: a multi-center randomized double-blind placebo-control trial]Sheng-fa Pan
Department of Orthopedics, Third Hospital of Peking University, Beijing 100083, China
Zhonghua Yi Xue Za Zhi 86:1888-90. 2006..CONCLUSION: Yunnan Baiyao is effective and safe in reducing the amount of intra-operative bleeding of cervical open-door laminoplasty...
Risk factors for pre-eclampsia in pregnant Chinese women with abnormal glucose metabolismYu Sun
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
Int J Gynaecol Obstet 101:74-6. 2008..To investigate the incidence and risk factors for pre-eclampsia in pregnant Chinese women with abnormal glucose metabolism...
Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- miceCarrie L Welch
Columbia University, Department of Medicine, P and S 8 401, 630 W 168th St, New York, NY 10032, USA
Circulation 116:2444-52. 2007..However, other species are highly resistant to plaque complications, and the specific processes predisposing to plaque destabilization and thrombosis are poorly understood...
