Steven S S Wang

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. ncbi Kinetic studies of the oxidation of glutathione in protein refolding buffer
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Bioprocess Biosyst Eng 33:277-86. 2010
  2. ncbi Amyloid fibrillation of hen egg-white lysozyme is inhibited by TCEP
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biochem Biophys Res Commun 381:639-42. 2009
  3. ncbi Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    Biophys Chem 144:78-87. 2009
  4. ncbi Diseases of protein aggregation and the hunt for potential pharmacological agents
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biotechnol J 3:165-92. 2008
  5. ncbi Investigating the influences of redox buffer compositions on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Biochim Biophys Acta 1794:1663-72. 2009
  6. ncbi Effects of glutathione on amyloid fibrillation of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Int J Biol Macromol 45:321-9. 2009
  7. ncbi Effects of dithiothreitol on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, 10617, Taiwan
    Eur Biophys J 39:1229-42. 2010
  8. ncbi Inhibition of amyloid fibril formation of beta-amyloid peptides via the amphiphilic surfactants
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei 10617, Taiwan
    Biochim Biophys Acta 1741:307-13. 2005
  9. ncbi The influence of phospholipid membranes on bovine calcitonin peptide's secondary structure and induced neurotoxic effects
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1 Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Int J Biochem Cell Biol 37:1656-69. 2005
  10. ncbi The influence of phospholipid membranes on bovine calcitonin secondary structure and amyloid formation
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, Taiwan 10617
    Protein Sci 14:1419-28. 2005

Collaborators

  • Shuichi Yamamoto
  • Hsuan Liang Liu
  • Wen Yih Chen
  • Yung Chang
  • Akon Higuchi
  • Kuan Nan Liu
  • Ming Shen Lin
  • Wen Sing Wen
  • Jeng Shiung Jan
  • Chia Min Lai
  • Rita P Y Chen
  • Po Ting Chen
  • Hui-Ting Tsai
  • Hui Ting Tsai
  • Ming-Shen Lin
  • Valerie H Lieu
  • Kristy M Hawkins
  • Yu Jiun Lin
  • Yi Ting Lee
  • Yun Chiao Huang
  • Jun Kun Lai
  • Chaur Jong Hu
  • Chih Yuan Chen
  • Tai Yan Liao
  • Hsiang Yun Wang
  • Shu Ting Wu
  • Liang-Yu Chen
  • Liang Yu Chen
  • Josephine W Wu
  • Chia Hung Wu
  • Fu-Jung Fan
  • Chia-Hung Wu
  • Hsiu Mei Chiu
  • Hsiu-Mei Chiu
  • Fu Jung Fan
  • Daniel F Shantz
  • David M Ford

Detail Information

Publications28

  1. ncbi Kinetic studies of the oxidation of glutathione in protein refolding buffer
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Bioprocess Biosyst Eng 33:277-86. 2010
    ..Moreover, the temperature dependence of the rate of GSH oxidation was modeled by Arrhenius and Eyring equations and resultant activation parameters were also presented...
  2. ncbi Amyloid fibrillation of hen egg-white lysozyme is inhibited by TCEP
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biochem Biophys Res Commun 381:639-42. 2009
    ..Moreover, our findings suggested that the TCEP-induced attenuated fibrillation is associated with disulfide disruption and structural unfolding of HEWL...
  3. ncbi Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    Biophys Chem 144:78-87. 2009
    ....
  4. ncbi Diseases of protein aggregation and the hunt for potential pharmacological agents
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biotechnol J 3:165-92. 2008
    ....
  5. ncbi Investigating the influences of redox buffer compositions on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Biochim Biophys Acta 1794:1663-72. 2009
    ..The results from this work may aid in comprehending the molecular mechanism(s) of amyloid fibrillogenesis for disulfide bonded proteins and the development of effective therapeutics for amyloidogenic diseases...
  6. ncbi Effects of glutathione on amyloid fibrillation of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Int J Biol Macromol 45:321-9. 2009
    ..We conclude that the attenuation of lysozyme fibrillation is strongly dependent upon the redox environment. Our data may contribute to decipher the molecular mechanism of amyloid fibrillation...
  7. ncbi Effects of dithiothreitol on the amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, 10617, Taiwan
    Eur Biophys J 39:1229-42. 2010
    ..Our data may contribute to rational design of effective therapeutic strategies for amyloid diseases...
  8. ncbi Inhibition of amyloid fibril formation of beta-amyloid peptides via the amphiphilic surfactants
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei 10617, Taiwan
    Biochim Biophys Acta 1741:307-13. 2005
    ..We believe that the outcome from this work will aid in the development and/or design of potential inhibitory agents against amyloid formation associated with Alzheimer's and other amyloid diseases...
  9. ncbi The influence of phospholipid membranes on bovine calcitonin peptide's secondary structure and induced neurotoxic effects
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1 Sec 4, Roosevelt Rd, Taipei 10617, Taiwan
    Int J Biochem Cell Biol 37:1656-69. 2005
    ....
  10. ncbi The influence of phospholipid membranes on bovine calcitonin secondary structure and amyloid formation
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, Taiwan 10617
    Protein Sci 14:1419-28. 2005
    ....
  11. ncbi Amyloid fibrillation and cytotoxicity of insulin are inhibited by the amphiphilic surfactants
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    Biochim Biophys Acta 1802:519-30. 2010
    ..The results from this work may contribute to the understanding of the molecular factors affecting amyloid fibrillation and the molecular mechanism(s) of the interactions between the membrane and amyloid proteins...
  12. ncbi Examining the influence of ultraviolet C irradiation on recombinant human γD-crystallin
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Mol Vis 16:2777-90. 2010
    ..Exposure to ultraviolet (UV) light is thought to perturb protein structure and eventually lead to aggregation. This work is aimed at exploring the effects of UV-C irradiation on recombinant human γD-crystallin (HGDC)...
  13. ncbi Exploring the inhibitory activity of short-chain phospholipids against amyloid fibrillogenesis of hen egg-white lysozyme
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    Biochim Biophys Acta 1811:301-13. 2011
    ....
  14. ncbi Curcumin's pre-incubation temperature affects its inhibitory potency toward amyloid fibrillation and fibril-induced cytotoxicity of lysozyme
    Kuan Nan Liu
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biochim Biophys Acta 1820:1774-86. 2012
    ..The research reported here is aimed at exploring the connection between curcumin's thermostability and its inhibitory activity toward the amyloid fibrillation of hen egg-white lysozyme (HEWL)...
  15. ncbi Inhibition of amyloid fibrillization of hen egg-white lysozymes by rifampicin and p-benzoquinone
    Valerie H Lieu
    Department of Chemical Engineering National Taiwan University, Taipei 10617, Taiwan
    Biotechnol Prog 23:698-706. 2007
    ....
  16. ncbi Effects of copolypeptides on amyloid fibrillation of hen egg-white lysozyme
    Wen Sing Wen
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Biopolymers 97:107-16. 2012
    ..The results of this work may contribute to the understanding of the molecular factors affecting amyloid fibrillation and the molecular mechanism(s) of the interactions between the unstructured polypeptides and the amyloid proteins...
  17. ncbi Stability of hen egg white lysozyme during denaturation is enhanced by pretreatment with supercritical carbon dioxide
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1 Sec 4 Roosevelt Road, Taipei, Taiwan
    J Biosci Bioeng 107:355-9. 2009
    ..The result of this study may provide supporting evidence that supercritical fluids serve as potential media for enhancing the activity of enzymes used in a variety of biochemical applications...
  18. ncbi Effect of sample loop dimension on lysozyme refolding in size-exclusion chromatography
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    J Chromatogr A 1161:56-63. 2007
    ..We believe that the outcome from this work may shed light on the development of a more effective strategy for refolding processes...
  19. ncbi L-Arginine reduces thioflavin T fluorescence but not fibrillation of bovine serum albumin
    Kuan Nan Liu
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Rd, Taipei, 10617, Taiwan
    Amino Acids 39:821-9. 2010
    ..Moreover, the use of ThT fluorescence assay to screen for potential inhibitors against amyloid fibrillation can give misleading results...
  20. ncbi Using isothermal titration calorimetry to real-time monitor the heat of metabolism: a case study using PC12 cells and Aβ(1-40)
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
    Colloids Surf B Biointerfaces 83:307-12. 2011
    ..This approach with rapid and direct measurement may provide not only real-time information for the effects of Aβ species on living cells but also a platform for the screening of drug candidates for AD...
  21. ncbi A highly sensitive peptide substrate for detecting two Aß-degrading enzymes: neprilysin and insulin-degrading enzyme
    Po Ting Chen
    Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan
    J Neurosci Methods 190:57-62. 2010
    ..As low as 0.1 nM of neprilysin and 0.2 nM of insulin-degrading enzyme can be detected...
  22. ncbi Deactivation of isoamylase and β-amylase in the agitated reactor under supercritical carbon dioxide
    Steven S S Wang
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, 10617, Taiwan
    Bioprocess Biosyst Eng 33:1007-15. 2010
    ..We believe that the outcome from this work may provide a better understanding of the effects of agitation and pressure in enzyme deactivation behavior under SC-CO2...
  23. ncbi Hydrogen exchange-mass spectrometry analysis of beta-amyloid peptide structure
    Steven S-S Wang
    Department of Chemical Engineering, Texas A and M University, College Station, Texas 77843-3122, USA
    Biochemistry 42:9507-14. 2003
    ....
  24. ncbi A Kinetic Analysis of the Mechanism of beta-Amyloid Induced G Protein Activation
    Steven S-S Wang
    Department of Chemical Engineering, Texas A> and M University, College Station, TX 77843-3122, USA
    J Theor Biol 221:269-78. 2003
    ..This work demonstrates the utility of an engineering approach to examining steps in the mechanism of A beta-induced cell toxicity and could provide insight into our understanding of the mechanism of Alzheimer's disease...
  25. ncbi Investigation of the mechanism of beta-amyloid fibril formation by kinetic and thermodynamic analyses
    Ming Shen Lin
    Department of Chemical and Materials Engineering, National Central University, Jhong Li, Taiwan 320
    Langmuir 24:5802-8. 2008
    ..Our study provides an insight into the discriminative mechanisms of beta-amyloid aggregation via kinetics and thermodynamics, especially the first reported thermodynamics information obtained by ITC...
  26. ncbi Poly-L-lysine templated silicas: using polypeptide secondary structure to control oxide pore architectures
    Kristy M Hawkins
    Department of Chemical Engineering, Texas A and M University, College Station, 77843, USA
    J Am Chem Soc 126:9112-9. 2004
    ..3-1.7 nm in size, in good agreement with expected values. Our results suggest a new avenue for synthesizing porous oxides with highly tuneable pore sizes and shapes under mild conditions...
  27. ncbi Kinetics and enthalpy measurements of interaction between beta-amyloid and liposomes by surface plasmon resonance and isothermal titration microcalorimetry
    Ming Shen Lin
    Department of Chemical and Materials Engineering, National Central University, Jhong Li 320, Taiwan
    Colloids Surf B Biointerfaces 58:231-6. 2007
    ..When the composition of liposomes is zwitterionic lipids, the interaction of Abeta with liposomes is predominantly hydrophobic force. In contrast, the driving force of interaction of charged lipids with Abeta is electrostatic...
  28. ncbi Development of a novel diffusion-based method to estimate the size of the aggregated Abeta species responsible for neurotoxicity
    Steven S-S Wang
    Department of Chemical Engineering, Texas A and M University, TAMU 3122, College Station, Texas 77843-3122, USA
    Biotechnol Bioeng 80:50-9. 2002
    ....