Shun Fen Tzeng

Summary

Affiliation: National Cheng Kung University
Country: Taiwan

Publications

  1. ncbi request reprint Neural progenitors isolated from newborn rat spinal cords differentiate into neurons and astroglia
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan, Taiwan, ROC
    J Biomed Sci 9:10-6. 2002
  2. ncbi request reprint Inhibitors of DNA binding in neural cell proliferation and differentiation
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, 1 Ta Hsiueh Road, Tainan City, Taiwan 70101
    Neurochem Res 28:45-52. 2003
  3. ncbi request reprint Downregulation of inducible nitric oxide synthetase by neurotrophin-3 in microglia
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan City, Taiwan
    J Cell Biochem 90:227-33. 2003
  4. ncbi request reprint Prostaglandins and cyclooxygenases in glial cells during brain inflammation
    Shun Fen Tzeng
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    Curr Drug Targets Inflamm Allergy 4:335-40. 2005
  5. doi request reprint Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling
    Yu Peng Liu
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurochem 113:213-27. 2010
  6. ncbi request reprint Inhibition of lipopolysaccharide-induced microglial activation by preexposure to neurotrophin-3
    Shun Fen Tzeng
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurosci Res 81:666-76. 2005
  7. ncbi request reprint Regulation of microglial activities by glial cell line derived neurotrophic factor
    Yu Ping Chang
    Department of Life Sciences, National Cheng Kung University, No 1 Ta Hsueh Road, Tainan, Taiwan 70101
    J Cell Biochem 97:501-11. 2006
  8. ncbi request reprint Tumor necrosis factor-alpha and interleukin-18 modulate neuronal cell fate in embryonic neural progenitor culture
    Yu Peng Liu
    Department of Life Sciences, National Cheng Kung University, 1 Ta Hsueh Rd, Tainan 70101, Taiwan
    Brain Res 1054:152-8. 2005
  9. ncbi request reprint TNF-alpha/IFN-gamma-induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling
    Han Yun Hsiao
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    Glia 55:214-23. 2007
  10. doi request reprint Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia
    Wen Hsin Lu
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurosci Res 91:694-705. 2013

Collaborators

  • Chung Shi Yang
  • Henrich Cheng
  • Synthia H Sun
  • Shih Chieh Hung
  • Song Kun Shyue
  • Oi Tong Mak
  • Shih Hwa Chiou
  • De Maw Chuang
  • I Ming Jou
  • Jung Yu C Hsu
  • Jiunn Der Liao
  • Jau-Shyong Hong
  • Kuan Min Fang
  • Yu Peng Liu
  • Chih Yen Wang
  • Mei Chun Chen
  • Tsung I Lee
  • Kuan Ming Fang
  • Wen Hsin Lu
  • Ti Ju Chan
  • Jung Shun Lee
  • Yi Ting Wu
  • Jen Kun Chen
  • Chia Chun Wang
  • Shu Ping Lin
  • Hsin I Lin
  • Han Yun Hsiao
  • Ying Chao Chang
  • Yu Ping Chang
  • Wen Hsin Chen
  • Pi Ju Tsai
  • Ming Hong Tai
  • Peiyuan F Hsieh
  • Bo Cheng Tzou
  • Tzu Chien Lin
  • Jing Wen Wang
  • Shi Zhang Ma
  • Jun Jen Liu
  • Po See Chen
  • Wen Ruei Chang
  • Ti Chun Chan
  • Chun I Sze
  • Ching Lin Tsai
  • Seng Sheen Fan
  • Yu Min Kuo
  • Hsing Hong Chen
  • Lu Shiun Her
  • Chung Hua Tsai
  • Yi Hung Huang
  • Cheng Han Lin
  • Yi Ying Liu
  • Hung Jiun Liaw
  • Ying Lan Wang
  • Ming Chao Huang
  • May Jywan Tsai
  • Chia Hua Chen
  • Tsung Jung Wu
  • Jia Jin J Chen
  • A Min Huang
  • Lung Yu
  • Chao Ching Huang
  • Hsueh Te Lee
  • Chien Jung Ho
  • Wen Ying Chen
  • Wei Ming Liang
  • Ching Jiunn Tseng
  • Jon Son Kuo
  • Jen Pey Wu
  • Yuh Ling Liu
  • Pei Ru Lin
  • Ming Hong Chang
  • Dah Ren Ni
  • Lie Gan Chia
  • Yuh Pin Ho
  • Lee Ju Cheng

Detail Information

Publications31

  1. ncbi request reprint Neural progenitors isolated from newborn rat spinal cords differentiate into neurons and astroglia
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan, Taiwan, ROC
    J Biomed Sci 9:10-6. 2002
    ..Thus, the neural progenitors isolated from newborn rat spinal cords in combination with neurotrophic factors may provide a tool for cell therapy in SCI patients...
  2. ncbi request reprint Inhibitors of DNA binding in neural cell proliferation and differentiation
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, 1 Ta Hsiueh Road, Tainan City, Taiwan 70101
    Neurochem Res 28:45-52. 2003
    ..Here we summarize recent findings regarding the regulation of Id proteins in neural cells and discuss the possible mechanisms of Id-regulated neurogenesis...
  3. ncbi request reprint Downregulation of inducible nitric oxide synthetase by neurotrophin-3 in microglia
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan City, Taiwan
    J Cell Biochem 90:227-33. 2003
    ..These findings indicate that NT-3 may serve as an anti-inflammatory factor to suppress microglial activation...
  4. ncbi request reprint Prostaglandins and cyclooxygenases in glial cells during brain inflammation
    Shun Fen Tzeng
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    Curr Drug Targets Inflamm Allergy 4:335-40. 2005
    ..In addition, the mechanism by which PGs mediate signaling is discussed...
  5. doi request reprint Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling
    Yu Peng Liu
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurochem 113:213-27. 2010
    ....
  6. ncbi request reprint Inhibition of lipopolysaccharide-induced microglial activation by preexposure to neurotrophin-3
    Shun Fen Tzeng
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurosci Res 81:666-76. 2005
    ..This suggests that an NT-enriched microenvironment may be favorable for preventing the inflammatory reaction of microglia...
  7. ncbi request reprint Regulation of microglial activities by glial cell line derived neurotrophic factor
    Yu Ping Chang
    Department of Life Sciences, National Cheng Kung University, No 1 Ta Hsueh Road, Tainan, Taiwan 70101
    J Cell Biochem 97:501-11. 2006
    ..Taken together, our results indicate that GDNF has a positive regulatory effect on microglial activities, such as phagocytosis and the upregulation of adhesion molecules...
  8. ncbi request reprint Tumor necrosis factor-alpha and interleukin-18 modulate neuronal cell fate in embryonic neural progenitor culture
    Yu Peng Liu
    Department of Life Sciences, National Cheng Kung University, 1 Ta Hsueh Rd, Tainan 70101, Taiwan
    Brain Res 1054:152-8. 2005
    ....
  9. ncbi request reprint TNF-alpha/IFN-gamma-induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling
    Han Yun Hsiao
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    Glia 55:214-23. 2007
    ..Collectively, PGE(2) may enhance T/I-induced astrocytic activation by augmenting iNOS/NO production through EP2-mediated cross-talk between cAMP/PKA and IP3/Ca(2+) signaling pathways...
  10. doi request reprint Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia
    Wen Hsin Lu
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurosci Res 91:694-705. 2013
    ..2013 Wiley Periodicals, Inc...
  11. ncbi request reprint Neuronal morphological change of size-sieved stem cells induced by neurotrophic stimuli
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan City, Taiwan ROC
    Neurosci Lett 367:23-8. 2004
    ..The findings indicate that neurotrophic signaling and cAMP-dependent signaling might promote the neuronal differentiation of SSCs...
  12. pmc Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury
    Chih Yen Wang
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Biomed Sci 18:13. 2011
    ..To consider an appropriate time window for giving a promising therapeutic treatment for subacute and chronic SCI, global changes of proteins in the injured center at the longer survival time points after SCI remains to be elucidated...
  13. ncbi request reprint Effects of malonate C60 derivatives on activated microglia
    Shun Fen Tzeng
    Department of Biology, National Cheng Kung University, Tainan City, Taiwan
    Brain Res 940:61-8. 2002
    ..Therefore, our results suggest that the C60 derivatives might increase microglial SOD enzymatic activity which causes microglial morphological transformation from the activated amoeboid phenotype to the resting ramified form...
  14. pmc Effects of combinatorial treatment with pituitary adenylate cyclase activating peptide and human mesenchymal stem cells on spinal cord tissue repair
    Kuan Min Fang
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    PLoS ONE 5:e15299. 2010
    ....
  15. doi request reprint Retinoic acid mediates the expression of glutamate transporter-1 in rat astrocytes through genomic RXR action and non-genomic protein kinase C signaling pathway
    Ti Ju Chan
    Department of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan
    J Neurochem 121:537-50. 2012
    ..These results suggest that RA reduces astrocytic GLT-1 levels through both RXR-mediated inhibition at the transcriptional level and triggering activation of protein kinase C which reduces cell surface GLT-1 levels...
  16. ncbi request reprint Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium
    Chung Shi Yang
    Center for Nanomedicine Research, National Health Research Institutes, Zhunan, Taiwan, ROC
    J Cell Biochem 103:825-34. 2008
    ..This information provides a useful approach for treating Cd(2+)-induced CNS neurological disorders...
  17. doi request reprint Microglial phagocytosis attenuated by short-term exposure to exogenous ATP through P2X receptor action
    Kuan Min Fang
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurochem 111:1225-37. 2009
    ....
  18. doi request reprint Expression of macrophage inflammatory protein-1α and monocyte chemoattractant protein-1 in glioma-infiltrating microglia: involvement of ATP and P2X₇ receptor
    Kuan Min Fang
    Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
    J Neurosci Res 89:199-211. 2011
    ....
  19. doi request reprint Mps one binder 2 gene upregulation in the stellation of astrocytes induced by cAMP-dependent pathway
    Kuan Min Fang
    Institute of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan
    J Cell Biochem 113:3019-28. 2012
    ..Based on our findings, we suggest that Mob2 is involved in PKA signaling-mediated astrocytic stellation...
  20. doi request reprint Inhibitory regulation of glutamate aspartate transporter (GLAST) expression in astrocytes by cadmium-induced calcium influx
    Yu Peng Liu
    Department of Life Sciences, National Cheng Kung University, Tainan City, Taiwan
    J Neurochem 105:137-50. 2008
    ....
  21. doi request reprint Delayed granulocyte colony-stimulating factor treatment promotes functional recovery in rats with severe contusive spinal cord injury
    Jung Shun Lee
    Department of Surgery Division of Neurosurgery, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Spine (Phila Pa 1976) 37:10-7. 2012
    ....
  22. doi request reprint Reactive oxygen species-induced cell death of rat primary astrocytes through mitochondria-mediated mechanism
    Chia Chun Wang
    Department of Life Sciences, National Cheng Kung University, Tainan City, Taiwan
    J Cell Biochem 107:933-43. 2009
    ..This mitochondria-mediated but caspase-3-independent apoptotic pathway may be involved in oxidative stress-induced astrocytic cell death in the injured CNS...
  23. doi request reprint Enhanced cell growth and tumorigenicity of rat glioma cells by stable expression of human CD133 through multiple molecular actions
    Kuan Min Fang
    Institute of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan
    Glia 61:1402-17. 2013
    ....
  24. doi request reprint Role of ciliary neurotrophic factor in microglial phagocytosis
    Tsung I Lee
    Department of Life Sciences, National Cheng Kung University, Tainan City, 70101, Taiwan
    Neurochem Res 34:109-17. 2009
    ..Our results also suggest that the upregulation of alphav integrin by CNTF could be involved in the increased phagocytotic activity of microglia...
  25. ncbi request reprint Pituitary adenylate cyclase-activating polypeptide prevents cell death in the spinal cord with traumatic injury
    Wen Hsin Chen
    Department of Life Sciences, National Cheng Kung University, 1 Ta Hsueh Road, Tainan 70101, Taiwan
    Neurosci Lett 384:117-21. 2005
    ..Our findings indicate the beneficial effect of PACAP for the treatment of spinal cord injury (SCI)...
  26. ncbi request reprint Characterization of surface modification on microelectrode arrays for in vitro cell culture
    Shu Ping Lin
    Institute of Biomedical Engineering, National Cheng Kung University, No 1 Ta Hsueh Road, Tainan, Taiwan, Republic of China
    Biomed Microdevices 10:99-111. 2008
    ....
  27. ncbi request reprint Behavior, neurochemistry and histology after intranigral lipopolysaccharide injection
    Peiyuan F Hsieh
    Division of Neurology, 160 Chung Kang Road Section 3, Taichung, Taiwan 40705, ROC
    Neuroreport 13:277-80. 2002
    ..Unilateral LPS decreased dopamineric neurons ipsilaterally but increased contralaterally. This study provides the first evidence of behavioral hyperactivity, epinephrine suppression and neuronal plasticity in the LPS model of PD...
  28. ncbi request reprint Gene transfer of glial cell line-derived neurotrophic factor promotes functional recovery following spinal cord contusion
    Ming Hong Tai
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Exp Neurol 183:508-15. 2003
    ..This research should provide information for developing a clinical strategy for GDNF gene therapy...
  29. ncbi request reprint Early-life fluoxetine exposure reduced functional deficits after hypoxic-ischemia brain injury in rat pups
    Ying Chao Chang
    Department of Pediatrics, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Guang University College of Medicine, Kaohsiung, Taiwan
    Neurobiol Dis 24:101-13. 2006
    ..These findings suggest that functional deficits after HI in the developing brain can be reduced by agents that enhance neural plasticity and neurogenesis through CREB activation...
  30. ncbi request reprint Neuroprotection of glial cell line-derived neurotrophic factor in damaged spinal cords following contusive injury
    Henrich Cheng
    Neural Regeneration Laboratory, Neurological Institute, Taipei Veterans General Hospital, Taiwan
    J Neurosci Res 69:397-405. 2002
    ..Together our results show that GDNF exerts behavioral and anatomic neuroprotection following SCI. Additionally, GDNF-activated MAP kinase and Bcl-2 signaling may contribute to neuronal survival after spinal cord contusion...
  31. ncbi request reprint Experimental spinal cord injury induced an increase of extracellular ascorbic acid concentration in anesthetized rats: a microdialysis study
    Pi Ju Tsai
    Department of Education and Research, Taichung Veterans General Hospital, Taiwan
    Clin Chim Acta 362:94-100. 2005
    ..This on-line, continuous and automatic monitoring system can be applied to future investigations on the roles of ascorbic acid in spinal cord injuries...