Yeong Shiau Pu

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. pmc Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    J Biomed Sci 19:39. 2012
  2. pmc Cadmium burden and the risk and phenotype of prostate cancer
    Yi Chun Chen
    Department of Health Management, I Shou University, Kaohsiung 824, Taiwan
    BMC Cancer 9:429. 2009
  3. pmc Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
    J Biomed Sci 16:82. 2009
  4. ncbi request reprint Prognostic factors for metastatic urothelial carcinoma treated with cisplatin and 5-fluorouracil-based regimens
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    Urology 69:479-84. 2007
  5. ncbi request reprint Urinary arsenic profile affects the risk of urothelial carcinoma even at low arsenic exposure
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    Toxicol Appl Pharmacol 218:99-106. 2007
  6. doi request reprint Arsenic methylation capability, heme oxygenase-1 and NADPH quinone oxidoreductase-1 genetic polymorphisms and the stage and grade of urothelial carcinomas
    Steven K Huang
    Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Urol Int 80:405-12. 2008
  7. doi request reprint Clinical outcome of Taiwanese men with clinically localized prostate cancer post-radical prostatectomy: a comparison with other ethnic groups
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Aging Male 13:10-7. 2010
  8. ncbi request reprint Long-term outcome of hand-assisted laparoscopic radical nephroureterectomy for upper-tract urothelial carcinoma: comparison with open surgery
    Shiu Dong Chung
    Department of Urology, Far Eastern Memorial Hospital, Ban Ciao, Taipei County, Taiwan
    J Endourol 21:595-9. 2007
  9. ncbi request reprint Cytotoxicity of arsenic trioxide to transitional carcinoma cells
    Yeong Shiau Pu
    Department of Urology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
    Urology 60:346-50. 2002
  10. ncbi request reprint Association of vitamin D receptor FokI polymorphism with prostate cancer risk, clinicopathological features and recurrence of prostate specific antigen after radical prostatectomy
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University, Kaohsiung, Taiwan
    Int J Cancer 119:1902-7. 2006

Collaborators

Detail Information

Publications79

  1. pmc Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    J Biomed Sci 19:39. 2012
    ..However, the correlation between PKCζ expression and the clinical outcome in RCC patients is unclear. We examined the level of PKCζ expression in human RCC...
  2. pmc Cadmium burden and the risk and phenotype of prostate cancer
    Yi Chun Chen
    Department of Health Management, I Shou University, Kaohsiung 824, Taiwan
    BMC Cancer 9:429. 2009
    ..Studies on the association between prostate cancer and cadmium exposure have yielded conflicting results. This study explored cadmium burden on the risk and phenotype of prostate cancer in men with no evident environmental exposure...
  3. pmc Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
    J Biomed Sci 16:82. 2009
    ..Our results suggest different locations of EGFR expression may be associated with human renal tumorigenesis...
  4. ncbi request reprint Prognostic factors for metastatic urothelial carcinoma treated with cisplatin and 5-fluorouracil-based regimens
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    Urology 69:479-84. 2007
    ..The present study sought to identify factors that predict for patient survival after treatment with P-HDFL-based regimens...
  5. ncbi request reprint Urinary arsenic profile affects the risk of urothelial carcinoma even at low arsenic exposure
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    Toxicol Appl Pharmacol 218:99-106. 2007
    ..Subjects who have an unfavorable urinary arsenic profile have an increased UC risk even at low exposure levels...
  6. doi request reprint Arsenic methylation capability, heme oxygenase-1 and NADPH quinone oxidoreductase-1 genetic polymorphisms and the stage and grade of urothelial carcinomas
    Steven K Huang
    Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Urol Int 80:405-12. 2008
    ..To explore the distribution of the arsenic methylation capability in patients with different stages and grades of UCs, 100 UC cases were recruited between September 2002 and May 2004 for this study...
  7. doi request reprint Clinical outcome of Taiwanese men with clinically localized prostate cancer post-radical prostatectomy: a comparison with other ethnic groups
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Aging Male 13:10-7. 2010
    ..We aimed to compare the clinical outcome in patient treated with RP among different ethnic groups and to identify significant prognostic factors in Taiwanese patients...
  8. ncbi request reprint Long-term outcome of hand-assisted laparoscopic radical nephroureterectomy for upper-tract urothelial carcinoma: comparison with open surgery
    Shiu Dong Chung
    Department of Urology, Far Eastern Memorial Hospital, Ban Ciao, Taipei County, Taiwan
    J Endourol 21:595-9. 2007
    ..To evaluate the efficacy and long-term outcome of hand-assisted laparoscopic radical nephroureterectomy (HALNU) in treating upper urinary-tract transitional-cell carcinoma (UT-TCC)...
  9. ncbi request reprint Cytotoxicity of arsenic trioxide to transitional carcinoma cells
    Yeong Shiau Pu
    Department of Urology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
    Urology 60:346-50. 2002
    ....
  10. ncbi request reprint Association of vitamin D receptor FokI polymorphism with prostate cancer risk, clinicopathological features and recurrence of prostate specific antigen after radical prostatectomy
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University, Kaohsiung, Taiwan
    Int J Cancer 119:1902-7. 2006
    ..Furthermore, the VDR polymorphism could be used as a prognostic marker for localized prostate cancer after radical prostatectomy...
  11. ncbi request reprint Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    Biochem Pharmacol 71:751-60. 2006
    ..In conclusion, the combination of paclitaxel and PD168393 produced a profound synergistic growth inhibition of AIPC cells. Combining PD168393 with paclitaxel may have clinical benefits and warrants further investigation...
  12. doi request reprint Polymorphism of inflammatory genes and arsenic methylation capacity are associated with urothelial carcinoma
    Chia Chang Wu
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan Department of Urology, Taipei Medical University Shuang Ho Hospital, Taipei, Taiwan
    Toxicol Appl Pharmacol 272:30-6. 2013
    ..In contrast, a significant decrease in UC risk was found in subjects who carried the IL-8 -251 T/T genotype for each SD increase in DMA%. ..
  13. doi request reprint Joint effect of arsenic methylation profile and NNK metabolites on urothelial carcinoma
    Chia Chang Wu
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan
    J Urol 188:1701-5. 2012
    ..We explored the joint effects of urinary NNK metabolites and arsenic species on urothelial carcinoma risk...
  14. doi request reprint The polymorphisms of P53 codon 72 and MDM2 SNP309 and renal cell carcinoma risk in a low arsenic exposure area
    Chao Yuan Huang
    Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 257:349-55. 2011
    ..Taken together, this is the first study to show that a variant genotype of p53 Arg(72)Pro or MDM2 SNP309 may modify the arsenic-related RCC risk even in a non-obvious arsenic exposure area...
  15. ncbi request reprint Laparoscopic radical prostatectomy monotherapy, a more aggressive yet less invasive option, is oncologically effective in selected men with high-risk prostate cancer having only one D'Amico risk factor: experience from an Asian tertiary referral center
    Huai Ching Tai
    1 Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    J Endourol 28:165-71. 2014
    ..To present oncologic results of laparoscopic radical prostatectomy (LRP) monotherapy for men with high-risk, localized prostate cancer, and to find factors associated with a good prognosis via surgery alone...
  16. ncbi request reprint Gemcitabine and ifosfamide as a second-line treatment for cisplatin-refractory metastatic urothelial carcinoma: a phase II study
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, ROC
    Anticancer Drugs 18:487-91. 2007
    ..The gemcitabine and ifosfamide regimen has an acceptable toxicity profile, but shows insufficient clinical activity in patients with cisplatin-refractory urothelial carcinoma to warrant further testing...
  17. ncbi request reprint High incidence of and risk factors for metachronous bilateral upper tract urothelial carcinoma in Taiwan
    Po Chien Huang
    Department of Urology, National Taiwan University Hospital, Taipei
    Int J Urol 13:864-9. 2006
    ..A higher rate of bilateral metachronous upper tract (UT) UC was noted in Taiwan. The incidence and risk factors were largely unknown and hence were explored in the study...
  18. doi request reprint Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Int J Cancer 133:14-20. 2013
    ..In conclusion, AA-UUC patients tend to be younger and female, and have more advanced renal disease. Notably, AA exposure was associated with an increased risk for developing synchronous bilateral and metachronous contralateral UUC...
  19. doi request reprint Significant associations of prostate-specific antigen nadir and time to prostate-specific antigen nadir with survival in prostate cancer patients treated with androgen-deprivation therapy
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University Hospital, Taiwan
    Aging Male 15:34-41. 2012
    ..We evaluated the prognostic significance of PSA nadir and time to PSA nadir as well as their interactive effect on prostate cancer-specific mortality (PCSM) and all-cause mortality (ACM) after ADT...
  20. pmc 2-methoxyestradiol induces mitotic arrest, apoptosis, and synergistic cytotoxicity with arsenic trioxide in human urothelial carcinoma cells
    Kuan Lin Kuo
    Department of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    PLoS ONE 8:e68703. 2013
    ..The synergistic antitumor effect with As2O3 provides a novel implication in clinical treatment of UC. ..
  21. doi request reprint Protective effects of plasma alpha-tocopherols on the risk of inorganic arsenic-related urothelial carcinoma
    Chi Jung Chung
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan
    Sci Total Environ 409:1039-45. 2011
    ..These results suggest that plasma alpha-tocopherol might modify the risk of inorganic arsenic-related UC...
  22. ncbi request reprint Arsenic trioxide as a novel anticancer agent against human transitional carcinoma--characterizing its apoptotic pathway
    Yeong Shiau Pu
    Department of Urology, National Taiwan University Hospital and National Taiwan University College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan 100, ROC
    Anticancer Drugs 13:293-300. 2002
    ..The As(2)O(3)-mediated cytotoxicity appeared to go through the conventional apoptotic pathway. Our results have clinical implications and warrant further investigation...
  23. ncbi request reprint Phase II trial of weekly paclitaxel, cisplatin plus infusional high dose 5-fluorouracil and leucovorin for metastatic urothelial carcinoma
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    J Urol 177:84-9; discussion 89. 2007
    ..We tested the efficacy and toxicity of adding paclitaxel to that regimen...
  24. doi request reprint Urinary total arsenic and 8-hydroxydeoxyguanosine are associated with renal cell carcinoma in an area without obvious arsenic exposure
    Chao Yuan Huang
    Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 262:349-54. 2012
    ..002). In conclusion, higher urinary 8-OHdG was a strong predictor of the RCC. High levels of 8-OHdG combined with urinary total arsenic might be indicative of arsenic-induced RCC...
  25. ncbi request reprint Weekly paclitaxel and high-dose 5-fluorouracil plus leucovorin in hormone-refractory prostate cancer: in vitro combined effects and a phase II trial
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    Urol Oncol 25:207-13. 2007
    ..In vitro data suggest that the combined cytotoxicity may be sequence dependent. Thus, we explored the combined effects of the 2 agents, both in vitro and in vivo...
  26. ncbi request reprint Stopping smoking might reduce tumour recurrence in nonmuscle-invasive bladder cancer
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    BJU Int 100:281-6; discussion 286. 2007
    ....
  27. doi request reprint Gene polymorphisms of glutathione S-transferase omega 1 and 2, urinary arsenic methylation profile and urothelial carcinoma
    Chi Jung Chung
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan
    Sci Total Environ 409:465-70. 2011
    ..17; 95% CI, 0.03 - 0.88; p=0.03). Large-scale studies will be required to verify the association between the single nucleotide polymorphisms of arsenic-metabolism-related enzymes and UC risk...
  28. doi request reprint A cocktail regimen of intravesical mitomycin-C, doxorubicin, and cisplatin (MDP) for non-muscle-invasive bladder cancer
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Urol Oncol 30:421-7. 2012
    ..To compare the efficacy and toxicity profiles of 3 intravesical regimens, including doxorubicin alone, bacillus Calmette-Guerin (BCG), and a cocktail regimen, in the prevention of bladder cancer recurrence...
  29. doi request reprint Long-term oncologic outcomes of hand-assisted retroperitoneoscopic radical nephrectomy to treat clinically localized renal cell carcinoma
    Shun Fa Hung
    Department of Urology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    J Formos Med Assoc 111:41-5. 2012
    ..To evaluate the long-term oncological outcomes of hand-assisted retroperitoneoscopic radical nephrectomy (HARRN) for treating clinically localized renal cell carcinoma...
  30. ncbi request reprint Environmental tobacco smoke and arsenic methylation capacity are associated with urothelial carcinoma
    Chia Chang Wu
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan Department of Urology, Taipei Medical University Shuang Ho Hospital, Taipei, Taiwan
    J Formos Med Assoc 112:554-60. 2013
    ..We investigated the combined effects of cigarette smoking, exposure to secondhand smoke, and the presence of urinary total arsenic on the risk of developing UC...
  31. doi request reprint Comparison of genome-wide DNA methylation in urothelial carcinomas of patients with and without arsenic exposure
    Tse Yen Yang
    Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan Genomics Research Center, Academia Sinica, Taipei, Taiwan Molecular and Genomic Epidemiology Center, China Medical University Hospital, Taichung, Taiwan China Medical University, Taichung, Taiwan
    Environ Res 128:57-63. 2014
    ..Arsenic is a well-documented carcinogen of human urothelial carcinoma (UC) with incompletely understood mechanisms...
  32. ncbi request reprint Long-term follow-up of hand-assisted laparoscopic radical nephrectomy for organ-confined renal cell carcinoma
    Shiu Dong Chung
    Department of Urology, Far Eastern Memorial Hospital, Ban Ciao, Taipei County, Taiwan
    Urology 69:652-5. 2007
    ..To evaluate the efficacy and long-term outcomes of hand-assisted laparoscopic radical nephrectomy (HALRN) in treating clinically localized renal cell carcinoma...
  33. doi request reprint Characteristics of female non-muscle-invasive bladder cancer in Taiwan: association with upper tract urothelial carcinoma and end-stage renal disease
    Chung Hsin Chen
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan
    Urology 71:1155-60. 2008
    ..Urothelial carcinogenic mechanisms may differ between men and women. We investigated gender differences in the pathological characteristics and clinical outcomes of non-muscle-invasive bladder urothelial carcinoma (UC)...
  34. ncbi request reprint Urinary 8-hydroxydeoxyguanosine and urothelial carcinoma risk in low arsenic exposure area
    Chi Jung Chung
    Graduate Institute of Public Health, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 226:14-21. 2008
    ..The results suggest that oxidative DNA damage was associated with arsenic exposure, even at low urinary level of arsenic...
  35. ncbi request reprint Clinical and pathological data of 10 malignant pheochromocytomas: long-term follow up in a single institute
    Kuo How Huang
    Department of Urology, National Taiwan University Hospital, No 7 Chung Shan S Road, Taipei 100, Taiwan
    Int J Urol 14:181-5. 2007
    ..Malignant pheochromocytomas are rare. Many controversies still exists in clinical practice. We report the clinical and histological data of long-term follow up in 10 patients with malignant pheochromocytoma...
  36. ncbi request reprint Intermediate follow-up of hand-assisted retroperitoneoscopic nephroureterectomy for management of upper urinary tract urothelial carcinoma: comparison with open nephroureterectomy
    Shiu Dong Chung
    Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, Taipei, Taiwan
    Urology 69:1030-4. 2007
    ..To evaluate the oncologic outcomes of hand-assisted retroperitoneoscopic nephroureterectomy (HARNU) for upper urinary tract urothelial carcinoma and compare them with the data from conventional open surgery...
  37. doi request reprint Comparison between hand-assisted laparoscopic and retroperitoneoscopic nephroureterectomy for the management of upper urinary tract urothelial carcinoma: analysis of an intermediate follow-up period
    Shiu Dong Chung
    Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Taipei County, Taipei, Taiwan
    Surg Laparosc Endosc Percutan Tech 18:49-53. 2008
    ....
  38. pmc Quinolone prophylaxis in transrectal ultrasound guided prostate biopsy: an eight-year single center experience
    Bing Juin Chiang
    Department of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, No 7, Chung Shan S Road Zhongshan S Road, Zhongzheng District, Taipei City 10002, Taiwan Department of Urology, Cardinal Tien Hospital, College of Medicine, Fu Jen Catholic University, No 362, Zhongzheng Road, Xindian District, New Taipei City 231, Taiwan
    ScientificWorldJournal 2013:452107. 2013
    ..001). E. coli was the most common pathogen in both groups. Levofloxacin remains effective and appears superior to pipemidic acid based prophylaxis...
  39. doi request reprint Ling-Zhi polysaccharides potentiate cytotoxic effects of anticancer drugs against drug-resistant urothelial carcinoma cells
    Chao Yuan Huang
    Department of Urology, National Taiwan University Hospital, and College of Medicine, National Taiwan University, Taipei, Taiwan
    J Agric Food Chem 58:8798-805. 2010
    ..These molecular events of combined effects involved significant and earlier induction of Fas, caspase 3 and 8 activation, Bax and Bad up-regulation, Bcl-2 and Bcl-x(L) down-regulatuion, and cytochrome c release...
  40. ncbi request reprint Down-regulated expression of RhoA in human conventional renal cell carcinoma
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan, ROC
    Anticancer Res 28:2039-43. 2008
    ..In this study, the significance of RhoA expression in human RCC was characterized...
  41. ncbi request reprint Complete response of urothelial carcinoma to chemotherapy in renal allograft recipients: a two-case study
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, ROC
    Anticancer Res 26:3191-5. 2006
    ..Standard regimens for UC (e.g., M-VAC) carry substantial toxicity, which could be exacerbated in patients with end-stage renal disease receiving kidney transplantation, because of the need to take immunosuppressants for life...
  42. doi request reprint Polymorphisms in one-carbon metabolism pathway genes, urinary arsenic profile, and urothelial carcinoma
    Chi Jung Chung
    School of Public Health, Taipei Medical University, Taipei, Taiwan
    Cancer Causes Control 21:1605-13. 2010
    ..Gene polymorphisms in the one-carbon metabolism pathway could contribute to arsenic methylation capability through plasma folate and homocysteine metabolism, thereby increasing the susceptibility to urothelial carcinoma (UC) risk...
  43. doi request reprint Radical cystectomy in the treatment of bladder cancer: oncological outcome and survival predictors
    Chen Hsun Ho
    Department of Urology, National Taiwan University Hospital and College of Medicine, and Division of Urology, Department of Surgery, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Formos Med Assoc 108:872-8. 2009
    ..To better understand the result of radical cystectomy in the treatment of bladder cancer, we analyzed our data and reported the oncological outcomes and survival predictors...
  44. ncbi request reprint Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21(WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation
    Tzyh Chyuan Hour
    Department of Urology, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei 100, Taiwan, Republic of China
    Prostate 51:211-8. 2002
    ..The modulatory effects and molecular mechanisms of curcumin (CCM) on the cytotoxicity of chemotherapeutic agents to prostate cancer cells were explored...
  45. pmc Celecoxib-induced cytotoxic effect is potentiated by inhibition of autophagy in human urothelial carcinoma cells
    Kuo How Huang
    Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 8:e82034. 2013
    ..Taken together, the inhibition of autophagy enhances therapeutic efficacy of celecoxib in UC cells, suggesting a novel therapeutic strategy against UC. ..
  46. ncbi request reprint Prognostic significance of p53 and X-ray repair cross-complementing group 1 polymorphisms on prostate-specific antigen recurrence in prostate cancer post radical prostatectomy
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University Hospital, No 100 Shih chuan 1st Road, Kaohsiung, Taiwan
    Clin Cancer Res 13:6632-8. 2007
    ..We investigated the potential prognostic roles of p53 (codon 72) and XRCC1 (codons 194, 280, and 399) polymorphisms in clinical localized prostate cancer after radical prostatectomy...
  47. ncbi request reprint Resistance to paclitaxel is proportional to cellular total antioxidant capacity
    Balakrishnan Ramanathan
    Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
    Cancer Res 65:8455-60. 2005
    ..This, in turn, may then improve treatment outcomes by selecting out potentially responsive patients...
  48. doi request reprint Expression of stathmin in localized upper urinary tract urothelial carcinoma: correlations with prognosis
    Wei Chou Lin
    Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan
    Urology 74:1264-9. 2009
    ....
  49. ncbi request reprint Metallic ureteral stents in malignant ureteral obstruction: clinical factors predicting stent failure
    Po Ming Chow
    1 Department of Urology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    J Endourol 28:729-34. 2014
    ..Old age and high serum creatinine level are predictors for stent failure. Stents in patients with lower gastrointestinal cancers have longer functional duration. ..
  50. ncbi request reprint Malignant epithelioid angiomyolipoma of the kidney
    Kuo How Huang
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 106:S51-4. 2007
    ..Epithelioid AML is a potentially aggressive tumor. The prognosis is poor in metastatic disease. HMB-45 immunoreactivity is a useful marker to make diagnosis...
  51. ncbi request reprint Systemic therapy for metastatic urothelial carcinoma
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    BJU Int 101:795-803. 2008
  52. doi request reprint Washout gradient in dynamic contrast-enhanced MRI is associated with tumor aggressiveness of prostate cancer
    Yu Jen Chen
    Institute of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan
    J Magn Reson Imaging 36:912-9. 2012
    ....
  53. doi request reprint Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk
    Chi Jung Chung
    School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan
    Sci Total Environ 409:1638-42. 2011
    ..Furthermore, the NNAL-Gluc/free NNAL ratio was a better biomarker to evaluate UC risk than total NNAL...
  54. doi request reprint Diagnostic value of finger-guided prostate nodule biopsy combined with systemic random biopsy
    I Ni Chiang
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 108:713-8. 2009
    ....
  55. doi request reprint Long-term outcome of hand-assisted laparoscopic nephroureterectomy for pathologic T3 upper urinary tract urothelial carcinoma
    Shiu Dong Chung
    Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, Taipei, Taiwan
    J Endourol 23:75-80. 2009
    ..To determine the feasibility and long-term outcomes of hand-assisted laparoscopic nephroureterectomy (HALNU) compared with open nephroureterectomy (ONU) in the management of pT(3)N0 upper urinary tract urothelial carcinoma (UUT-UC)...
  56. doi request reprint Effect of urinary total arsenic level and estimated glomerular filtration rate on the risk of renal cell carcinoma in a low arsenic exposure area
    Chao Yuan Huang
    Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    J Urol 185:2040-4. 2011
    ..We explored the relationship between urinary total arsenic and risk of renal cell carcinoma, and investigated whether having hypertension or a low estimated glomerular filtration rate would modify the risk of renal cell carcinoma...
  57. ncbi request reprint Clinical outcome of Taiwanese men with metastatic prostate cancer compared with other ethnic groups
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Urology 72:1287-92. 2008
    ..We sought to compare the survival outcome in patients with metastatic prostate cancer among different ethnic groups and to identify independent prognostic factors affecting overall survival in Taiwanese patients...
  58. ncbi request reprint The 18th International Symposium: Controversies in Prostate Cancer Diagnosis and Treatment
    Yeong Shiau Pu
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Jpn J Clin Oncol 35:680-9. 2005
  59. ncbi request reprint Major complications and associated risk factors of transrectal ultrasound guided prostate needle biopsy: a retrospective study of 1875 cases in taiwan
    I Ni Chiang
    Department of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    J Formos Med Assoc 106:929-34. 2007
    ..We tried to determine the associated risk factors of patients who suffered from major complications that required hospitalization after TRUS guided prostate needle biopsies...
  60. ncbi request reprint Primary amyloidosis of the urinary bladder
    Chao Yuan Huang
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan, ROC
    J Formos Med Assoc 105:164-7. 2006
    ..Correct diagnosis relies on clinical alertness and the use of a special staining technique during pathologic examination...
  61. ncbi request reprint Plasma folate level, urinary arsenic methylation profiles, and urothelial carcinoma susceptibility
    Yung Kai Huang
    Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Food Chem Toxicol 46:929-38. 2008
    ..The results of this study may identify the susceptible subpopulations and provide insight into the carcinogenic mechanisms of arsenic even at low arsenic exposure...
  62. doi request reprint Targeting epidermal growth factor receptor/human epidermal growth factor receptor 2 signalling pathway by a dual receptor tyrosine kinase inhibitor afatinib for radiosensitisation in murine bladder carcinoma
    Yu Chieh Tsai
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    Eur J Cancer 49:1458-66. 2013
    ..Afatinib has therapeutic value as a radiosensitiser of murine bladder cancer cells. The synergism between afatinib and radiation likely enhances DNA damage, leading to increased cell apoptosis...
  63. doi request reprint Impact of prostate-specific antigen (PSA) nadir and time to PSA nadir on disease progression in prostate cancer treated with androgen-deprivation therapy
    Shu Pin Huang
    Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Prostate 71:1189-97. 2011
    ..We evaluated the prognostic significance of PSA nadir and time to PSA nadir as well as their potential interactive effect on the progression of disease after ADT...
  64. pmc Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells
    Kuo How Huang
    Graduate Institute of Toxicology, College of Medicine, National Taiwan University, and National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 7:e33615. 2012
    ..The down-regulation of ER chaperone GRP78 by siRNA, EGCG, or proteosome inhibitor potentiated the cytotoxicity of celecoxib in UC cells. These findings provide a new treatment strategy against UC...
  65. doi request reprint Comparative genomic hybridization study of arsenic-exposed and non-arsenic-exposed urinary transitional cell carcinoma
    Ling I Hsu
    The Genomics Research Center, Academia Sinica, Taipei, Taiwan
    Toxicol Appl Pharmacol 227:229-38. 2008
    ..The findings suggest that long-term arsenic exposure may increase the chromosome abnormality in TCC, and 17p loss plays an important role in arsenic-induced urinary carcinogenesis...
  66. doi request reprint Diffusion MRI predicts transrectal ultrasound biopsy results in prostate cancer detection
    Yu Jen Chen
    Institute of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan
    J Magn Reson Imaging 33:356-63. 2011
    ..To evaluate the ability of diffusion tensor imaging (DTI) to predict the transrectal ultrasound (TRUS) biopsy outcomes in persons who have no history of previous TRUS biopsy and present with elevated prostate-specific antigen (PSA) levels...
  67. pmc Aristolochic acid-associated urothelial cancer in Taiwan
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan 10002
    Proc Natl Acad Sci U S A 109:8241-6. 2012
    ..We conclude that exposure to aristolochic acid contributes significantly to the incidence of UUC in Taiwan, a finding with significant implications for global public health...
  68. pmc Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7
    Yung Ho Hsu
    Department of Internal Medicine, Taipei Medical University Shuang Ho Medical Center, Taipei, Taiwan
    Am J Pathol 176:3050-61. 2010
    ..Therefore, podocalyxin can serve as a biomarker to identify renal cell carcinoma patients with higher metastatic potential for more aggressive intervention at earlier clinical stages...
  69. ncbi request reprint 8-Oxoguanine DNA glycosylase and MutY homolog are involved in the incision of arsenite-induced DNA adducts
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei 10002, Taiwan, ROC
    Toxicol Sci 95:376-82. 2007
    ..These results suggest that As(2)O(3) induces the formation of only oxidative DNA adducts and that OGG1 and MYH are involved in this incision process...
  70. ncbi request reprint Set-up errors due to endorectal balloon positioning in intensity modulated radiation therapy for prostate cancer
    Chun Wei Wang
    Institute of Electrical Engineering, National Taiwan University, Taipei, Taiwan
    Radiother Oncol 84:177-84. 2007
    ..To investigate the set-up errors and deformation associated with daily placement of endorectal balloons in prostate radiotherapy...
  71. ncbi request reprint Using age-referenced prostate-specific antigen percentile to predict survival outcomes in screened Taiwanese men
    Chung Hsin Chen
    Department of Urology, National Taiwan University Hospital, Taipei, Taiwan
    Int J Cancer 132:1927-32. 2013
    ..The 10-year PCM rate for men with ≥ the 99th age-referenced PSA percentile was 3.9%, which was significantly higher than the rate of ≤ 0.5% in the lower percentile groups...
  72. doi request reprint Polymorphisms in cell cycle regulatory genes, urinary arsenic profile and urothelial carcinoma
    Chi Jung Chung
    Graduate Institute of Public Health, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 232:203-9. 2008
    ..The goal of our study was to evaluate the roles of cell cycle regulatory gene polymorphisms in the carcinogenesis of arsenic-related urothelial carcinoma (UC)...
  73. ncbi request reprint Enhanced suppression of prostate tumor growth by combining C-CAM1 gene therapy and angiogenesis inhibitor TNP-470
    Yeong Shiau Pu
    Department of Urology, National Taiwan University College of Medicine, Taipei, Taiwan 100, ROC
    Anticancer Drugs 13:743-9. 2002
    ..The novel strategy may have clinical implications for the treatment of prostate cancer...
  74. ncbi request reprint Choosing the ideal length of a double-pigtail ureteral stent according to body height: study based on a Chinese population
    Chen Hsun Ho
    Department of Urology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
    Urol Int 83:70-4. 2009
    ..We conducted this study to determine the ideal stent length according to body height, as data are limited...
  75. doi request reprint Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production
    Chen Hsun Ho
    Department of Urology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
    Urology 71:984.e7-8. 2008
    ..Postoperatively, her serum CEA level gradually returned to the normal range, and she had had no recurrence by 9 months postoperatively...
  76. doi request reprint Clinicopathological characteristics and survival outcome of arsenic related bladder cancer in taiwan
    Chung Hsin Chen
    Department of Urology, National Taiwan University College of Medicine and Hospital, Division of Urology, Taoyuan General Hospital, Taipei, Taiwan
    J Urol 181:547-52; discussion 553. 2009
    ..We compared clinicopathological characteristics and outcomes in patients with bladder cancer who were exposed to graded arsenic levels in drinking water...
  77. doi request reprint Acute encephalopathy following arsenic trioxide for metastatic urothelial carcinoma
    Chia Chi Lin
    Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
    Urol Oncol 26:659-61. 2008
    ..Arsenic trioxide in this dose and schedule can cause acute encephalopathy in patients with metastatic urothelial carcinoma who have received previous chemotherapy...
  78. ncbi request reprint A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
    Wei Chien Yuan
    Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
    Cancer Cell 20:214-28. 2011
    ..Our study indicates that the KLHL20-mediated PML degradation and HIF-1α autoregulation play key roles in tumor progression...
  79. doi request reprint Comparison of 6- and 12-core prostate biopsy in Taiwanese men: impact of total prostate-specific antigen, prostate-specific antigen density and prostate volume on prostate cancer detection
    I Ni Chiang
    Department of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    Urol Int 82:270-5. 2009
    ..We retrospectively compared 6- and 12-core prostate biopsies in Taiwanese men and evaluated the impact of prostate volume (PV), prostate-specific antigen (PSA), and PSA density (PSAD) on the prostate cancer detection rate (PCDR)...