Research Topics
| Li Heng PaoSummaryAffiliation: National Defense Medical Center Country: Taiwan Publications
| Collaborators
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Detail Information
Publications
Herb-drug interaction of 50 Chinese herbal medicines on CYP3A4 activity in vitro and in vivoLi Heng Pao
School of Pharmacy, National Defense Medical Center, 161 MinchuanEast Road Section 6, Taipei, Taiwan
Am J Chin Med 40:57-73. 2012..Mu Dan Pi, Ji Shiee Terng and Huang Qi were observed to have greatly increased in the C(max) and AUC of midazolam. This study provides evidence of possible herb-drug interactions involved with certain single herbs...
Simultaneous quantification of triazolam and its metabolites in human urine by liquid chromatography-tandem mass spectrometryRyh Nan Pan
Department of Disaster Management, Taiwan Police College, 153 Shing Lung Rd, Section 3, Taipei, Taiwan
J Anal Toxicol 35:170-5. 2011..The within- and between-run precisions were less than 15%, and accuracy was -12.33% to 9.76%. The method was proved to be accurate and specific, and it was applied to a urinary excretion study of triazolam in healthy Chinese volunteers...
Evaluation of chinese-herbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1Chang Ching Lin
School of Pharmacy, National Defense Medical Center, Taipei 114, Taiwan
Evid Based Complement Alternat Med 2012:967182. 2012..Moreover, GZ showed concentration-dependent manners both in vitro and in vivo, and the decrease of rOAT1 mRNA expression indicated that GZ not only inhibited function of OAT1 but also suppressed expression of OAT1...
Validated LC-MS-MS method for the determination of quetiapine in human plasma: application to a pharmacokinetic studyRyh Nan Pan
Department of Disaster Management, Taiwan Police College, Taipei, Taiwan, Republic of China
J Chromatogr Sci 50:277-82. 2012..2%. The lower limit of quantification was 1 ng/mL. The extraction recoveries of quetiapine were over 90%. The method is proved to be accurate and specific, and was applied to the pharmacokinetic study in healthy Chinese volunteers...
Determination of p-aminohippuric acid in rat plasma by liquid chromatography-tandem mass spectrometryHsien Yuan Fan
School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, ROC
J Chromatogr B Analyt Technol Biomed Life Sci 878:1643-6. 2010..1-->110.1 for PAH and acetaminophen, respectively. Good linearity is observed over the concentration range of 0.1-500 microg/ml. The method was proved to be accurate and reliable and was applied to a pharmacokinetic study in rat...
Simultaneous determination of triazolam and its metabolites in human plasma by liquid chromatography-tandem mass spectrometryRyh Nan Pan
Department of Disaster Management, Taiwan Police College, Taipei, Taiwan, ROC
J Chromatogr B Analyt Technol Biomed Life Sci 872:58-62. 2008..The within- and between-run precisions were less than 15.26% and accuracy was -8.08% to 13.33%. The method proved to be accurate and specific, and was applied to the pharmacokinetic study of triazolam in healthy Chinese volunteers...
Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of p-aminohippuric acid and inulin in rat plasma for renal function studyChang Ching Lin
School of Pharmacy, National Defense Medical Center, 9F, 161 Minchuan East Road, Section 6, Taipei, Taiwan, 114, Republic of China
Anal Bioanal Chem 398:857-65. 2010..This application was proven to be reliable and accurate and was successfully applied to a renal function study...
