Research Topics
Genomes and GenesSpecies | Wen Ying LeeSummaryAffiliation: National Cheng Kung University Country: Taiwan Publications
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Detail Information
Publications
Diagnosing invasive cystic hypersecretory duct carcinoma of the breast with fine needle aspiration cytology. A case reportW Y Lee
Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
Acta Cytol 43:273-6. 1999..The lining epithelium of the cysts atypically proliferates to form intraductal carcinoma. Only four cases of invasive cystic hypersecretory carcinoma have been reported...
Cytology of abnormal nipple discharge: a cyto-histological correlationWen Ying Lee
Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
Cytopathology 14:19-26. 2003..The sensitivity and specificity of the nonpalpable and palpable breast lesions were similar. Nipple discharge cytology is very helpful in detecting an underlying breast lesion even if the case has no palpable mass in the breast...
Frequent loss of BRCA1 nuclear expression in young women with breast cancer: an immunohistochemical study from an area of low incidence but early onsetWen Ying Lee
Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
Appl Immunohistochem Mol Morphol 10:310-5. 2002..However, c-erbB-2 and p53 gene expressions seem to have no important role in the adverse tumor behavior of breast cancer in young women...
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patientsWen Ying Lee
Department of Pathology, College of Medicine, National Cheng Kung University, Chi Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan 710, Taiwan
Clin Cancer Res 11:2222-8. 2005..We wanted to examine the clinical significance of RON and MET expression patterns in node-negative breast cancer...
Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIXChi long Chen
Department of Pathology, College of Medicine, Taipei Medical University, Taipei, Taiwan
Virchows Arch 457:53-61. 2010..GLUT1 expression (glycolytic phenotype) and CAIX expression (acid-resistant phenotype) may result in a powerful adaptive advantage and represent an aggressive phenotype...
Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cellsWen Ying Lee
Department of Pathology, Yung Kung Campus, Chi MeiMedical Center, Tainan, 710, Taiwan
Nutr Cancer 58:239-46. 2007..We conclude that genistein-induced alternations of gene expression involving metastasis may be exploited for devising chemopreventive and therapeutic strategies, particularly for early-stage breast cancer...
IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasivenessYueh Mei Hsu
Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan
J Cell Physiol 210:626-36. 2007..Thus, we conclude that KCC activation by IGF-1 plays an important role in IGF-1 receptor signaling to promote growth and spread of breast cancer cells...
Constitutive STAT5 activation correlates with better survival in cervical cancer patients treated with radiation therapyHelen H W Chen
Department of Radiation Oncology, National Cheng Kung University, Medical College and Hospital, Tainan, Taiwan
Int J Radiat Oncol Biol Phys 82:658-66. 2012..This study investigated the expression patterns of STAT1, STAT3, and STAT5 in cervical cancer and their associations with clinical outcomes in patients treated with radical radiation therapy...
Detection of carbonic anhydrase IX protein in the diagnosis of malignant pleural effusion by enzyme-linked immunosorbent assay and immunocytochemistryNai Ding Liao
Devision of Cytopathology, Department of Pathology, Chi Mei Medical Center, Tainan, Taiwan
Cancer Cytopathol 120:269-75. 2012..The aim was to evaluate the utility of CAIX expression for the detection of malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry...
Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancerHelen H W Chen
Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan
Breast Cancer Res Treat 103:167-75. 2007....
Diagnostic value of metabolic phenotypes in malignant pleural effusions: expression of GLUT1 and CAIX by immunocytochemistryNai Ding Liao
Department of Cytopathology, Chi Mei Medical Center, Tainan, Taiwan
Cancer Cytopathol 119:346-53. 2011..GLUT1 and CAIX are the hallmarks of metabolic change in cancer cells. The aim of this study was to evaluate the usefulness of GLUT1 and CAIX expression to the detection of cancer cells in pleural effusions...
Chromosomal gain of 3q and loss of 11q often associated with nodal metastasis in early stage cervical squamous cell carcinomaKuo Feng Huang
Department of Obstetrics and Gynecology, Chi Mei Medical Center, Tainan, Taiwan
J Formos Med Assoc 106:894-902. 2007..Delineation of genetic changes is critical to understanding the molecular basis of tumor progression, as well as for identifying genetic markers for early identification of patients at high risk for a poor outcome...
Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancerWen-Ying Lee
Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
Oncology 66:429-38. 2004..S100A4 expression appears to be an earlier step in the metastatic progression compared to Met expression in early-stage breast carcinoma...
p53 and c-erbB-2 but not bcl-2 are predictive of metastasis-free survival in breast cancer patients receiving post-mastectomy adjuvant radiotherapy in TaiwanHelen H W Chen
Department of Radiation Oncology, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
Jpn J Clin Oncol 32:332-9. 2002..CONCLUSION: Expressions of p53 and c-erbB-2 are independent predictors of MFS in this Taiwanese population. Further research should be conducted on their application in the treatment and follow-up of patients...
