Wen Ying Lee

Summary

Affiliation: National Cheng Kung University
Country: Taiwan

Publications

  1. ncbi Diagnosing invasive cystic hypersecretory duct carcinoma of the breast with fine needle aspiration cytology. A case report
    W Y Lee
    Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
    Acta Cytol 43:273-6. 1999
  2. ncbi Cytology of abnormal nipple discharge: a cyto-histological correlation
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
    Cytopathology 14:19-26. 2003
  3. ncbi Frequent loss of BRCA1 nuclear expression in young women with breast cancer: an immunohistochemical study from an area of low incidence but early onset
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
    Appl Immunohistochem Mol Morphol 10:310-5. 2002
  4. ncbi Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
    Oncology 66:429-38. 2004
  5. ncbi Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients
    Wen Ying Lee
    Department of Pathology, College of Medicine, National Cheng Kung University, Chi Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan 710, Taiwan
    Clin Cancer Res 11:2222-8. 2005
  6. ncbi p53 and c-erbB-2 but not bcl-2 are predictive of metastasis-free survival in breast cancer patients receiving post-mastectomy adjuvant radiotherapy in Taiwan
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
    Jpn J Clin Oncol 32:332-9. 2002
  7. ncbi Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 63:1093-100. 2005
  8. doi Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIX
    Chi long Chen
    Department of Pathology, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Virchows Arch 457:53-61. 2010
  9. ncbi Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells
    Wen Ying Lee
    Department of Pathology, Yung Kung Campus, Chi MeiMedical Center, Tainan, 710, Taiwan
    Nutr Cancer 58:239-46. 2007
  10. doi Constitutive STAT5 activation correlates with better survival in cervical cancer patients treated with radiation therapy
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University, Medical College and Hospital, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 82:658-66. 2012

Collaborators

Detail Information

Publications17

  1. ncbi Diagnosing invasive cystic hypersecretory duct carcinoma of the breast with fine needle aspiration cytology. A case report
    W Y Lee
    Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
    Acta Cytol 43:273-6. 1999
    ..The lining epithelium of the cysts atypically proliferates to form intraductal carcinoma. Only four cases of invasive cystic hypersecretory carcinoma have been reported...
  2. ncbi Cytology of abnormal nipple discharge: a cyto-histological correlation
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
    Cytopathology 14:19-26. 2003
    ..The sensitivity and specificity of the nonpalpable and palpable breast lesions were similar. Nipple discharge cytology is very helpful in detecting an underlying breast lesion even if the case has no palpable mass in the breast...
  3. ncbi Frequent loss of BRCA1 nuclear expression in young women with breast cancer: an immunohistochemical study from an area of low incidence but early onset
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan
    Appl Immunohistochem Mol Morphol 10:310-5. 2002
    ..However, c-erbB-2 and p53 gene expressions seem to have no important role in the adverse tumor behavior of breast cancer in young women...
  4. ncbi Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer
    Wen Ying Lee
    Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
    Oncology 66:429-38. 2004
    ..To formulate individually tailored therapy for patients with early-stage breast cancer, it is necessary to identify biomarkers for predicting metastasis and survival...
  5. ncbi Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients
    Wen Ying Lee
    Department of Pathology, College of Medicine, National Cheng Kung University, Chi Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan 710, Taiwan
    Clin Cancer Res 11:2222-8. 2005
    ..We wanted to examine the clinical significance of RON and MET expression patterns in node-negative breast cancer...
  6. ncbi p53 and c-erbB-2 but not bcl-2 are predictive of metastasis-free survival in breast cancer patients receiving post-mastectomy adjuvant radiotherapy in Taiwan
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
    Jpn J Clin Oncol 32:332-9. 2002
    ..We conducted a study to evaluate p53, bcl-2 and c-erbB-2 as predictors of prognosis in breast cancer patients receiving post-mastectomy radiotherapy, which has not been well defined in the Taiwanese population...
  7. ncbi Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 63:1093-100. 2005
    ..To investigate the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in cervical cancer and their association with clinical outcome in patients treated with radical radiotherapy...
  8. doi Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIX
    Chi long Chen
    Department of Pathology, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Virchows Arch 457:53-61. 2010
    ..GLUT1 expression (glycolytic phenotype) and CAIX expression (acid-resistant phenotype) may result in a powerful adaptive advantage and represent an aggressive phenotype...
  9. ncbi Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells
    Wen Ying Lee
    Department of Pathology, Yung Kung Campus, Chi MeiMedical Center, Tainan, 710, Taiwan
    Nutr Cancer 58:239-46. 2007
    ..We conclude that genistein-induced alternations of gene expression involving metastasis may be exploited for devising chemopreventive and therapeutic strategies, particularly for early-stage breast cancer...
  10. doi Constitutive STAT5 activation correlates with better survival in cervical cancer patients treated with radiation therapy
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University, Medical College and Hospital, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 82:658-66. 2012
    ..This study investigated the expression patterns of STAT1, STAT3, and STAT5 in cervical cancer and their associations with clinical outcomes in patients treated with radical radiation therapy...
  11. ncbi Glucose transporter 1 protein detected by enzyme-linked immunosorbent assay and immunocytochemistry: a useful diagnostic tool for malignant pleural effusions
    Nai Ding Liao
    Department of Cytopathology, Chi Mei Medical Center, Tainan, Taiwan
    Cancer Cytopathol 121:695-702. 2013
    ..The objective of this study was to determine the role of GLUT1 protein in diagnosing malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry...
  12. doi The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide
    Wen Ying Lee
    Department of Pathology, Chi Mei Hospital, Tainan, Taiwan Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 274:55-62. 2014
    ..In conclusion, we provide novel evidence underlying HO-1's antitumor mechanism. CO, a byproduct of HO-1, suppresses HSP90 protein activity, and the induction of HO-1 may possess potential as a cancer therapeutic. ..
  13. ncbi IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness
    Yueh Mei Hsu
    Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan
    J Cell Physiol 210:626-36. 2007
    ..Thus, we conclude that KCC activation by IGF-1 plays an important role in IGF-1 receptor signaling to promote growth and spread of breast cancer cells...
  14. doi Detection of carbonic anhydrase IX protein in the diagnosis of malignant pleural effusion by enzyme-linked immunosorbent assay and immunocytochemistry
    Nai Ding Liao
    Devision of Cytopathology, Department of Pathology, Chi Mei Medical Center, Tainan, Taiwan
    Cancer Cytopathol 120:269-75. 2012
    ..The aim was to evaluate the utility of CAIX expression for the detection of malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry...
  15. doi Diagnostic value of metabolic phenotypes in malignant pleural effusions: expression of GLUT1 and CAIX by immunocytochemistry
    Nai Ding Liao
    Department of Cytopathology, Chi Mei Medical Center, Tainan, Taiwan
    Cancer Cytopathol 119:346-53. 2011
    ..GLUT1 and CAIX are the hallmarks of metabolic change in cancer cells. The aim of this study was to evaluate the usefulness of GLUT1 and CAIX expression to the detection of cancer cells in pleural effusions...
  16. ncbi Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer
    Helen H W Chen
    Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan
    Breast Cancer Res Treat 103:167-75. 2007
    ....
  17. ncbi Chromosomal gain of 3q and loss of 11q often associated with nodal metastasis in early stage cervical squamous cell carcinoma
    Kuo Feng Huang
    Department of Obstetrics and Gynecology, Chi Mei Medical Center, Tainan, Taiwan
    J Formos Med Assoc 106:894-902. 2007
    ..Delineation of genetic changes is critical to understanding the molecular basis of tumor progression, as well as for identifying genetic markers for early identification of patients at high risk for a poor outcome...