Yao Haur Kuo
Affiliation: National Research Institute of Chinese Medicine
Kuo Y, Kuo Y, Yu A, Wu M, Ong C, Yang Kuo L, et al
. Two novel sesquiterpene lactones, cytotoxic vernolide-A and -B, from Vernonia cinerea. Chem Pharm Bull (Tokyo). 2003;51:425-6 pubmed
..02, 0.05, 0.53, 0.04 microg/ml for KB, DLD-1, NCI-661, and Hela, respectively); vernolide-B had marginal cytoxicity (ED(50)=3.78, 5.88, 6.42 microg/ml for KB, NCI-661, and Hela, respectively). ..
Kuo Y, Hwang S, Yang Kuo L, Lee Y, Li S, Shen Y. A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana. Chem Pharm Bull (Tokyo). 2002;50:1607-8 pubmed
..The structure of 1 was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively...