C C Kuo

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. ncbi Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Republic of China
    Mol Pharmacol 51:1077-83. 1997
  2. ncbi Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan, Republic of China
    Biophys J 75:2845-57. 1998
  3. ncbi A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taiwan, Republic of China
    Mol Pharmacol 54:712-21. 1998
  4. ncbi Facilitation of recovery from inactivation by external Na+ and location of the activation gate in neuronal Na+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Republic of China
    J Neurosci 20:5639-46. 2000
  5. ncbi Inhibition of Na(+) current by diphenhydramine and other diphenyl compounds: molecular determinants of selective binding to the inactivated channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Taiwan
    Mol Pharmacol 57:135-43. 2000
  6. ncbi Recovery from inactivation of t-type ca2+ channels in rat thalamic neurons
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan
    J Neurosci 21:1884-92. 2001
  7. ncbi Zn2+ modulation of neuronal transient K+ current: fast and selective binding to the deactivated channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, National Taiwan University Hospital, Taipei 100, Taiwan, Republic of China
    Biophys J 77:2552-62. 1999
  8. ncbi Deactivation retards recovery from inactivation in Shaker K+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei 100, Taiwan, Republic of China
    J Neurosci 17:3436-44. 1997

Collaborators

Detail Information

Publications8

  1. ncbi Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Republic of China
    Mol Pharmacol 51:1077-83. 1997
    ....
  2. ncbi Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan, Republic of China
    Biophys J 75:2845-57. 1998
    ....
  3. ncbi A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taiwan, Republic of China
    Mol Pharmacol 54:712-21. 1998
    ..Thus, there may be correlative conformational changes for the making of the receptor on the extracellular side of the channel during the gating process...
  4. ncbi Facilitation of recovery from inactivation by external Na+ and location of the activation gate in neuronal Na+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Republic of China
    J Neurosci 20:5639-46. 2000
    ....
  5. ncbi Inhibition of Na(+) current by diphenhydramine and other diphenyl compounds: molecular determinants of selective binding to the inactivated channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei, Taiwan
    Mol Pharmacol 57:135-43. 2000
    ....
  6. ncbi Recovery from inactivation of t-type ca2+ channels in rat thalamic neurons
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, and Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan
    J Neurosci 21:1884-92. 2001
    ..T-channels thus might have a more rigid hinge and a more abrupt conformational change in the inactivation machinery associated with opening and closing of the pore...
  7. ncbi Zn2+ modulation of neuronal transient K+ current: fast and selective binding to the deactivated channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, National Taiwan University Hospital, Taipei 100, Taiwan, Republic of China
    Biophys J 77:2552-62. 1999
    ....
  8. ncbi Deactivation retards recovery from inactivation in Shaker K+ channels
    C C Kuo
    Department of Physiology, National Taiwan University College of Medicine, Taipei 100, Taiwan, Republic of China
    J Neurosci 17:3436-44. 1997
    ....