Jia Horng Kao

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. ncbi request reprint GB virus C infection in hemodialysis patients: molecular evidence for nosocomial transmission
    J H Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan
    J Infect Dis 180:191-4. 1999
  2. ncbi request reprint Hepatitis B virus genotypes and hepatocellular carcinoma in Taiwan
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, Department of Internal Medicine and Department of Medical Research, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei 100, Taiwan
    Intervirology 46:400-7. 2003
  3. ncbi request reprint SEN virus infection in patients with chronic hepatitis C: preferential coinfection with hepatitis C genotype 2a and no effect on response to therapy with interferon plus ribavirin
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Infect Dis 187:307-10. 2003
  4. pmc Occult hepatitis B virus infection and clinical outcomes of patients with chronic hepatitis C
    Jia Horng Kao
    Graduate Institute of Clinical Medicine Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:4068-71. 2002
  5. ncbi request reprint Sequence analysis of pre-S/surface and pre-core/core promoter genes of hepatitis B virus in chronic hepatitis C patients with occult HBV infection
    Jia Horng Kao
    Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Med Virol 68:216-20. 2002
  6. pmc Hepatitis D virus genotypes in intravenous drug users in taiwan: decreasing prevalence and lack of correlation with hepatitis B virus genotypes
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:3047-9. 2002
  7. ncbi request reprint Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
    Gastroenterology 124:327-34. 2003
  8. ncbi request reprint Hepatitis B viral genotypes: clinical relevance and molecular characteristics
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, 7 Chung Shan South Road, Taipei 100, Taiwan
    J Gastroenterol Hepatol 17:643-50. 2002
  9. ncbi request reprint Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus
    J H Kao
    Graduate Institute of Clinical Medicine, Department of Internal Medicine and Hepatitis Research Center, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Hepatology 34:817-23. 2001
  10. pmc Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:1207-9. 2002

Detail Information

Publications136 found, 100 shown here

  1. ncbi request reprint GB virus C infection in hemodialysis patients: molecular evidence for nosocomial transmission
    J H Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan
    J Infect Dis 180:191-4. 1999
    ..These results suggest that GBV-C plays a minimal role in causing hepatitis in Taiwanese HD patients and in nosocomial transmission...
  2. ncbi request reprint Hepatitis B virus genotypes and hepatocellular carcinoma in Taiwan
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, Department of Internal Medicine and Department of Medical Research, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei 100, Taiwan
    Intervirology 46:400-7. 2003
    ....
  3. ncbi request reprint SEN virus infection in patients with chronic hepatitis C: preferential coinfection with hepatitis C genotype 2a and no effect on response to therapy with interferon plus ribavirin
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Infect Dis 187:307-10. 2003
    ..These results suggest that SENV has a specific link to HCV genotype 2a and that SENV infection has no apparent effect on coexisting chronic hepatitis C...
  4. pmc Occult hepatitis B virus infection and clinical outcomes of patients with chronic hepatitis C
    Jia Horng Kao
    Graduate Institute of Clinical Medicine Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:4068-71. 2002
    ..In conclusion, these data suggest that occult HBV infection does not have clinical significance in chronic hepatitis C patients residing in areas where HBV infection is endemic...
  5. ncbi request reprint Sequence analysis of pre-S/surface and pre-core/core promoter genes of hepatitis B virus in chronic hepatitis C patients with occult HBV infection
    Jia Horng Kao
    Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Med Virol 68:216-20. 2002
    ..001). In conclusion, the data suggest occult HBV infection is not uncommon in chronic hepatitis C patients in Taiwan, and a novel core promoter mutant may be associated with the absence of circulating HBsAg in these patients...
  6. pmc Hepatitis D virus genotypes in intravenous drug users in taiwan: decreasing prevalence and lack of correlation with hepatitis B virus genotypes
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:3047-9. 2002
    ..From 1986 to 1997, the average rate of decrease in the prevalence of HDV infection in this population was 4.7%/year...
  7. ncbi request reprint Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
    Gastroenterology 124:327-34. 2003
    ..We investigated the prevalence of T1762/A1764 basal core promoter mutant in a cohort of 250 genotype B- or C-infected HBV carriers with different stages of liver disease to clarify a possible role for this mutant in hepatocarcinogenesis...
  8. ncbi request reprint Hepatitis B viral genotypes: clinical relevance and molecular characteristics
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, 7 Chung Shan South Road, Taipei 100, Taiwan
    J Gastroenterol Hepatol 17:643-50. 2002
    ..Further studies to clarify the molecular virological factors that contribute to these differences are awaited...
  9. ncbi request reprint Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus
    J H Kao
    Graduate Institute of Clinical Medicine, Department of Internal Medicine and Hepatitis Research Center, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Hepatology 34:817-23. 2001
    ..8% (2 of 244) and 1.9% (2 of 103), respectively. In conclusion, superinfection of HBV on hepatitis B carriers indeed occurs and may cause acute exacerbations, albeit at a low frequency even in hyperendemic areas of HBV infection...
  10. pmc Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:1207-9. 2002
    ..002). In conclusion, patients with genotype C infection have a more aggressive clinical phenotype than do those with genotype B infection, which contributes to the former group's progressive liver disease and poor clinical outcomes...
  11. ncbi request reprint Transmission of hepatitis C virus in Asia: past and present perspectives
    J H Kao
    Graduate Institute of Clinical Medicine, Department of Internal Medicine and Hepatitis Research Center, National Taiwan University College of Medicine and Taipei
    J Gastroenterol Hepatol 15:E91-6. 2000
    ....
  12. ncbi request reprint Prevalence and implication of a newly identified infectious agent (SEN virus) in Taiwan
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei 100, Taiwan
    J Infect Dis 185:389-92. 2002
    ..These results suggest that SENV-D/H infection is common in high-risk groups in Taiwan but that SENV-D/H infection is not associated with hepatitis...
  13. pmc Clinical and virological aspects of blood donors infected with hepatitis B virus genotypes B and C
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, and Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 40:22-5. 2002
    ..Precore stop codon mutation is common in HBeAg-negative HBV carriers, irrespective of HBV genotypes. In contrast, precore C-1858 strains are rarely identified in Taiwanese HBV genotype C...
  14. doi request reprint Association of metabolic profiles with hepatic fibrosis in chronic hepatitis C patients with genotype 1 or 2 infection
    Ching Sheng Hsu
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, Taiwan
    J Gastroenterol Hepatol 25:970-7. 2010
    ..However, the influence of hepatitis C virus (HCV) genotypes, especially genotype 1 and 2, on the association between metabolic profiles and hepatic fibrosis remains unknown...
  15. doi request reprint Determinants of spontaneous surface antigen loss in hepatitis B e antigen-negative patients with a low viral load
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Hepatology 55:68-76. 2012
    ..2 (95% CI, 7.8-22.1) for HBsAg level <10 versus ≥ 1000 IU/mL. When compared to HBV DNA level by receiver operating characteristic curve analysis, HBsAg level served as a better predictor of both 5-year and 10-year HBsAg loss...
  16. doi request reprint Interleukin 28B genetic polymorphisms and viral factors help identify HCV genotype-1 patients who benefit from 24-week pegylated interferon plus ribavirin therapy
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Antivir Ther 17:477-84. 2012
    ..Whether these factors would identify those patients who can benefit from a shorter duration of therapy remains unclear...
  17. ncbi request reprint Mutations in the NS5A and E2-PePHD regions of hepatitis C virus genotype 1b and response to combination therapy of interferon plus ribavirin
    Sheng Shun Yang
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    Liver Int 23:426-33. 2003
    ..NS5A and E2 proteins of hepatitis C virus (HCV) may repress the IFN-induced RNA-dependent protein kinase (PKR), and thus have the potential to influence the response of HCV to IFN therapy; however, this issue remains controversial...
  18. ncbi request reprint Impact of hepatitis D virus infection on the long-term outcomes of patients with hepatitis B virus and HIV coinfection in the era of highly active antiretroviral therapy: a matched cohort study
    Wang Huei Sheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 44:988-95. 2007
    ..The influence of HDV infection on the responses to highly active antiretroviral therapy and hepatic complications in patients with HBV-HIV coinfection remains uncertain...
  19. ncbi request reprint Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan, ROC
    J Hepatol 43:235-42. 2005
    ..Adiponectin induces insulin sensitivity and modulates inflammatory responses. We thus studied the implications of adiponectin in patients with chronic hepatitis C virus (HCV) infection inherently linked to insulin resistance...
  20. ncbi request reprint Subgenotypes of hepatitis B virus genotype C do not correlate with disease progression of chronic hepatitis B in Taiwan
    Tai Chung Tseng
    Department of Internal Medicine, Division of Gastroenterology, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Liver Int 27:983-8. 2007
    ..Hepatitis B virus (HBV) genotype C (HBV/C) has two subgenotypes: HBV/Cs and Ce. The prevalence and clinical implications of subgenotype Cs and Ce in Taiwanese HBV carriers remain unknown...
  21. ncbi request reprint Prevalence and clinical implications of HFE gene mutations (C282Y and H63D) in patients with chronic hepatitis B and C in Taiwan
    Yone Han Mah
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan
    Liver Int 25:214-9. 2005
    ..The implication of hemochromatosis (HFE) gene mutations in chronic viral hepatitis remains controversial. We therefore studied the prevalence of HFE mutations and their impact on the progression of chronic viral hepatitis in Taiwan...
  22. ncbi request reprint Ribavirin and interferon is effective for hepatitis C virus clearance in hepatitis B and C dually infected patients
    Chun Jen Liu
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Hepatology 37:568-76. 2003
    ..In dually infected patients, the treatment may alter the dominant, ruling hepatitis virus...
  23. ncbi request reprint Interferon alpha-2b with and without ribavirin in the treatment of hepatitis B e antigen-positive chronic hepatitis B: a randomized study
    Chun Jen Liu
    National Taiwan University College of Medicine and National Taiwan University Hospital, Taipai, Taiwan
    Hepatology 43:742-9. 2006
    ..0%; P = .002). In conclusion, for the treatment of HBeAg-positive chronic hepatitis B, adding ribavirin does not seem to increase the efficacy of IFN...
  24. ncbi request reprint Early viral kinetics during treatment of chronic hepatitis C virus infection with pegylated interferon alpha plus ribavirin in Taiwan
    Ching Sheng Hsu
    Department of Hepatogastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, Taiwan
    Intervirology 50:310-5. 2007
    ..Whether this functions in Taiwanese patients remains unknown. Studying the early HCV kinetics in Taiwanese patients may clarify this issue...
  25. ncbi request reprint Factors affecting early viral load decline of Asian chronic hepatitis C patients receiving pegylated interferon plus ribavirin therapy
    Ching Sheng Hsu
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei, Taiwan
    Antivir Ther 14:45-54. 2009
    ....
  26. ncbi request reprint Hepatitis B genotypes correlate with tumor recurrence after curative resection of hepatocellular carcinoma
    Jin De Chen
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Clin Gastroenterol Hepatol 2:64-71. 2004
    ..This study aims to investigate whether HBV genotypes influence the clinicopathologic features and long-term prognosis of patients after curative resection of HCC...
  27. ncbi request reprint Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men
    Ming Whei Yu
    Department of Public Health, Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan
    J Natl Cancer Inst 97:265-72. 2005
    ..Although chronic infection with hepatitis B virus (HBV) has been established as a cause of hepatocellular carcinoma (HCC), the roles of viral load and HBV genotype remain unclear...
  28. ncbi request reprint Dynamics of hepatitis B e antigen index ratio correlate with treatment response in chronic hepatitis B patients
    Chia Chi Wang
    Department of Internal Medicine, Division of Hepatogastroenterology, Buddhist Xindian Tzu Chi General Hospital, Taipei, Taiwan
    Liver Int 27:235-9. 2007
    ..Whether early dynamics of HBeAg index ratio could predict therapeutic endpoint of HBeAg seroconversion in patients receiving lamivudine remains unclear and thus deserves investigation...
  29. doi request reprint Young chronic hepatitis B patients with nucleos(t)ide analogue-induced hepatitis B e antigen seroconversion have a higher risk of HBV reactivation
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    J Infect Dis 206:1521-31. 2012
    ..It is unclear whether hepatitis B e antigen (HBeAg) seroconversion induced by nucleos(t)ide analogues (NUC) has a prognosis that is similar to that of spontaneous HBeAg seroconversion...
  30. ncbi request reprint Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Infect Dis 193:1258-65. 2006
    ..However, the independent and interactive effects of each known viral factor on the development of hepatocellular carcinoma (HCC) remain largely unknown...
  31. ncbi request reprint High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases
    Bing Fang Chen
    School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
    Gastroenterology 130:1153-68. 2006
    ..The interactions among pre-S deletion, precore (PC) mutation, and basal core promoter (BCP) mutation in various stages of chronic hepatitis B virus (HBV) infection remain unclear and were thus investigated in this study...
  32. pmc Serum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis C
    Tung Hung Su
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 10002, Taiwan
    Proc Natl Acad Sci U S A 110:7844-9. 2013
    ..025). In conclusion, serum miR-122 may serve as a surrogate of hepatic miR-122, and a higher pretreatment serum miR-122 level can help predict virologic responses to pegylated IFN plus ribavirin therapy...
  33. doi request reprint Distinct evolution and predictive value of hepatitis B virus precore and basal core promoter mutations in interferon-induced hepatitis B e antigen seroconversion
    Hung Chih Yang
    Department of Microbiology, Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, and Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Hepatology 57:934-43. 2013
    ..Conclusion: Quantitative analysis of PC and BCP mutants can predict IFN-induced HBeAg seroconversion and demonstrate their distinct evolution patterns during HBeAg seroconversion. (HEPATOLOGY 2013)...
  34. doi request reprint Risk stratification of hepatocellular carcinoma in hepatitis B virus e antigen-negative carriers by combining viral biomarkers
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, New Taipei, Taiwan
    J Infect Dis 208:584-93. 2013
    ..However, little is known regarding how well the combination of both viral biomarkers stratifies HCC risk...
  35. ncbi request reprint Noninvasive tests for the prediction of significant hepatic fibrosis in hepatitis C virus carriers with persistently normal alanine aminotransferases
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Liver Int 26:1087-94. 2006
    ..The diagnostic value of Doppler and various noninvasive indices in predicting significant hepatic fibrosis in hepatitis C virus (HCV) carriers with persistently normal alanine aminotransferases (PNALT) is unknown...
  36. ncbi request reprint Genotypic dominance and novel recombinations in HBV genotype B and C co-infected intravenous drug users
    Bing Fang Chen
    School of Medicine, Fu Jen Catholic University, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Med Virol 73:13-22. 2004
    ..The impact of recombination on the evolution of HBV and their clinical significance remains to be studied...
  37. doi request reprint Differential clinical and virologic impact of hepatitis B virus genotypes B and C on HIV-coinfected patients receiving lamivudine-containing highly active antiretroviral therapy
    Wang Huei Sheng
    Department of Internal Medicine, Ntional Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Clin Infect Dis 54:548-55. 2012
    ..The impact of hepatitis B virus (HBV) genotypes B and C on the clinical, immunologic, and virologic outcomes of human immunodeficiency virus (HIV)-infected patients with chronic HBV infection remains largely unknown...
  38. ncbi request reprint Influence of metabolic syndrome, viral genotype and antiviral therapy on superimposed fatty liver disease in chronic hepatitis C
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Antivir Ther 10:405-15. 2005
    ..The prevalence and clinical implications of non-alcoholic fatty liver disease in patients with chronic hepatitis C remain unknown in Taiwan...
  39. doi request reprint Interleukin 28B genetic polymorphisms play a minor role in identifying optimal treatment duration in HCV genotype 1 slow responders to pegylated interferon plus ribavirin
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Antivir Ther 17:1059-67. 2012
    ..Whether interleukin 28B (IL28B) single nucleotide polymorphism (SNP) genotypes and on-treatment viral responses can identify non-rapid virological response (RVR) patients who benefit from 48 or 72 weeks of therapy remains unclear...
  40. ncbi request reprint High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C
    Ching Sheng Hsu
    Department of Hepatogastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, Taiwan
    Liver Int 28:271-7. 2008
    ..We thus studied the impact of host, metabolic and viral factors on IR in CHC patients...
  41. doi request reprint HBsAg profiles in patients receiving peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses
    Ming Lung Yu
    Department of Internal Medicine, Kaohsiung Municipal Ta Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Infect Dis 202:86-92. 2010
    ..2% of patients achieved clearance of hepatitis B surface antigen (HBsAg) at 6 months after treatment; however, reactivation of HBV DNA was observed in 36.3%. We investigated the predictive potential of HBsAg quantification...
  42. ncbi request reprint High prevalence of occult hepatitis B virus infection in Taiwanese intravenous drug users
    Chih Lin Lin
    Department of Gastroenterology, Ren Ai Branch, Taipei City Hospital, Taipei, Taiwan
    J Med Virol 79:1674-8. 2007
    ..In addition, intravenous drug users with occult mixed genotype B and C infections have significantly higher viral loads than those with occult infection of single HBV genotype...
  43. doi request reprint Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: a multicenter, randomized controlled trial
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 47:1260-9. 2008
    ..Whether a 48-week course of combination therapy shows a better SVR rate than a 24-week course of such therapy among Asian patients with HCV-1 infection has not been confirmed in multicenter, randomized studies...
  44. ncbi request reprint Secular trend of age-specific prevalence of hepatitis B surface and e antigenemia in pregnant women in Taiwan
    Ho Hsiung Lin
    Department of Obstetrics and Gynecology, College of Medicine and the Hospital, National Taiwan University, Taipei, Taiwan
    J Med Virol 69:466-70. 2003
    ....
  45. ncbi request reprint Basal core-promoter mutant of hepatitis B virus and progression of liver disease in hepatitis B e antigen-negative chronic hepatitis B
    Chih Lin Lin
    Department of Gastroenterology, Taipei Municipal Jen Ai Hospital, Taipei, Taiwan
    Liver Int 25:564-70. 2005
    ..We thus investigated the association of hepatitis B virus (HBV) genotypes as well as precore/basal core-promoter mutations with the clinical and virological characteristics of patients with HBeAg-negative chronic hepatitis B in Taiwan...
  46. doi request reprint Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B
    Chun Jen Liu
    Graduate Institute of Clinical Medicine, Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei
    J Infect Dis 199:742-9. 2009
    ..This study investigated the role that HBV genotype and basal core promoter (BCP) mutation play in the expression of HBcAg...
  47. ncbi request reprint Lack of interferon sensitivity-determining region in the genome of hepatitis B virus genotype Ba
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Antivir Ther 9:895-903. 2004
    ..We therefore performed full-length viral genomic comparison between HBVs obtained from IFN responders and non-responders...
  48. ncbi request reprint Transmission of occult hepatitis B virus by transfusion to adult and pediatric recipients in Taiwan
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, 1 Chang Te Street, Taipei 100, Taiwan
    J Hepatol 44:39-46. 2006
    ..To address this, we investigated the incidence of post-transfusion HBV infection after receiving screened blood units in Taiwan...
  49. ncbi request reprint Evolution of Hepatitis B virus in an acute hepatitis B patient co-infected with genotypes B and C
    Bing Fang Chen
    School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
    J Gen Virol 87:39-49. 2006
    ..Recombination within the pre-S region emerged transiently and the pre-S deletion mutant was finally cleared...
  50. doi request reprint Association of lipid profiles with hepatitis C viral load in chronic hepatitis C patients with genotype 1 or 2 infection
    Ching Sheng Hsu
    Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei, Taiwan
    Am J Gastroenterol 104:598-604. 2009
    ..The aim of this study was to evaluate the impact of lipid profiles on HCV RNA levels in patients with genotypes 1 and 2...
  51. ncbi request reprint Clinical impact of GB virus C viremia on patients with HIV type 1 infection in the era of highly active antiretroviral therapy
    Wang Huei Sheng
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Clin Infect Dis 44:584-90. 2007
    ..The influence of GB virus C (GBV-C) viremia on clinical outcomes of patients with human immunodeficiency virus type 1 (HIV-1) infection remains controversial in the era of highly active antiretroviral therapy (HAART)...
  52. pmc Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy
    Ching Sheng Hsu
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei 23142, Taiwan
    Proc Natl Acad Sci U S A 108:3719-24. 2011
    ....
  53. doi request reprint Serum hepatitis B surface antigen concentration correlates with HBV DNA level in patients with chronic hepatitis B
    Tung Hung Su
    Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
    Antivir Ther 15:1133-9. 2010
    ..Therefore, we explored the possibility of hepatitis B surface antigen (HBsAg) quantification as a surrogate marker for HBV DNA level in CHB patients...
  54. ncbi request reprint Clinical aspects and outcomes of volunteer blood donors testing positive for hepatitis-C virus infection in Taiwan: a prospective study
    Chun Jen Liu
    Department of Internal Medicine, National Taiwan University College of Medicine, National Taiwan University Hospital, 1 Chang Te Street, Taipei 100, Taiwan
    Liver Int 23:148-55. 2003
    ..Whether previous or concurrent hepatitis-B virus (HBV) infection influences the natural history of HCV infection remains unknown. Thus, we followed the anti-HCV-positive blood donors who had past or concurrent HBV infection in Taiwan...
  55. ncbi request reprint Origin of serum hepatitis B virus in acute exacerbation: comparison with HBV in the liver and from other exacerbation
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Hepatology 40:310-17. 2004
    ..Supplementary material for this article can be found on the HEPATOLOGY website (http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html)...
  56. ncbi request reprint High prevalence of mixed genotype infections in hepatitis B virus infected intravenous drug users
    Bing Fang Chen
    School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
    J Med Virol 74:536-42. 2004
    ....
  57. ncbi request reprint End-of-treatment virologic response does not predict relapse after lamivudine treatment for chronic hepatitis B
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, China
    World J Gastroenterol 10:3574-8. 2004
    ..In HBeAg-negative patients, predictors for post-treatment relapse remain largely unknown. We therefore studied whether end-of-treatment virologic response correlated with relapse after lamivudine treatment...
  58. ncbi request reprint Hepatitis B virus genotypes and spontaneous hepatitis B e antigen seroconversion in Taiwanese hepatitis B carriers
    Jia Horng Kao
    Graduate Institute of Clinical Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    J Med Virol 72:363-9. 2004
    ....
  59. doi request reprint Pegylated interferon alfa-2a monotherapy for hemodialysis patients with acute hepatitis C
    Chen Hua Liu
    Department of Internal Medicine, Hepatitis Research Center, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 51:541-9. 2010
    ..Hemodialysis patients are at risk of hepatitis C virus (HCV) infection. However, little is known about the efficacy and safety of pegylated interferon (IFN) therapy for hemodialysis patients with acute hepatitis C...
  60. ncbi request reprint Naturally occurring hepatitis B surface gene variants in chronic hepatitis B virus infection: correlation with viral serotypes and clinical stages of liver disease
    Chun Jen Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taiwan
    J Med Virol 68:50-9. 2002
    ..Mutation hotspots differed between serotypes adw and adr. The FEQ of HBV surface protein is correlated positively with advancing age and severity of liver disease, and certain variants may contribute to the persistence of HBV infection...
  61. pmc Longitudinal change of HBsAg in HBeAg-negative patients with genotype B or C infection
    Tung Hung Su
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 8:e55916. 2013
    ..However, its role in disease monitoring of HBeAg-negative patients remains unclear. We aimed to investigate the longitudinal HBsAg change in HBeAg-negative carriers with HBV genotype B or C infection...
  62. doi request reprint Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Hepatology 57:441-50. 2013
    ..The annual incidence rate of HBeAg-negative hepatitis was lowered to 1.1% in patients with low levels of HBV DNA, HBsAg, and ALT...
  63. doi request reprint High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Gastroenterology 142:1140-1149.e3; quiz e13-4. 2012
    ..Patients with lower levels of hepatitis B surface antigen (HBsAg) have higher chances of losing HBsAg than those with high levels. However, little is known about whether higher levels of HBsAg increase risk for HCC...
  64. doi request reprint Serum hepatitis B virus-DNA levels correlate with long-term adverse outcomes in spontaneous hepatitis B e antigen seroconverters
    Tai Chung Tseng
    Department of Internal Medicine, Division of Gastroenterology, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    J Infect Dis 205:54-63. 2012
    ....
  65. ncbi request reprint Early acquisition of TT virus in infants: possible minor role of maternal transmission
    Ho Hsiung Lin
    Department of Obstetrics and Gynecology, College of Medicine and the Hospital, National Taiwan University, Taipei, Taiwan
    J Med Virol 66:285-90. 2002
    ..In conclusion, TTV viremia is common in pregnant Taiwanese women and their infants. However, the results suggest that maternal transmission may play only a minor role in early acquisition of TTV in infants...
  66. doi request reprint HCV core gene polymorphisms correlate with liver fibrosis but not sustained virological response in patients with genotype 1 infection
    Shih Jer Hsu
    Department of Internal Medicine, National Taiwan University Hospital, Yun Lin branch, Yun Lin County, Taiwan
    Antivir Ther 16:227-35. 2011
    ..Whether this phenomenon could be extrapolated to non-Japanese patients remains unclear. We evaluated the effect of aa substitutions in HCV-CR on clinicopathological features and treatment responses in Taiwanese patients...
  67. doi request reprint Peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses
    Chun Jen Liu
    National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Gastroenterology 136:496-504.e3. 2009
    ..We investigated the effects of combination therapy in patients infected with both HBV and HCV (genotypes 1, 2, or 3)...
  68. doi request reprint Serum hepatitis B surface antigen levels predict surface antigen loss in hepatitis B e antigen seroconverters
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Gastroenterology 141:517-25, 525.e1-2. 2011
    ..However, little is known about factors predicting HBsAg loss in patients who spontaneously clear hepatitis B e antigen (HBeAg)...
  69. doi request reprint The ratio of aminotransferase to platelets is a useful index for predicting hepatic fibrosis in hemodialysis patients with chronic hepatitis C
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Kidney Int 78:103-9. 2010
    ..Applying this simple index could decrease the need of percutaneous liver biopsy in this clinical setting...
  70. pmc Revisiting the stopping rule for hepatitis C genotype 1 patients treated with peginterferon plus ribavirin
    Ming Lung Yu
    Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 7:e52048. 2012
    ..We aimed to explore rapid stopping rules at week 4...
  71. doi request reprint Effect of host and viral factors on hepatitis B e antigen-positive chronic hepatitis B patients receiving pegylated interferon-α-2a therapy
    Tai Chung Tseng
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Antivir Ther 16:629-37. 2011
    ..However, baseline factors predicting favourable responses to PEG-IFN-α-2a remain largely unknown...
  72. doi request reprint A higher alanine aminotransferase level correlates with earlier hepatitis B e antigen seroconversion in lamivudine-treated chronic hepatitis B patients
    Tai Chung Tseng
    Department of Internal Medicine, Division of Hepatogastroenterology, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Liver Int 28:1034-41. 2008
    ..However, whether an even higher pretherapy serum ALT value or other viral factors could affect treatment responses remains unclear...
  73. ncbi request reprint Hepatitis B viral factors in HBeAg-negative carriers with persistently normal serum alanine aminotransferase levels
    Chih Lin Lin
    Department of Gastroenterology, Ren Ai Branch, Taipei City Hospital, and Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
    Hepatology 45:1193-8. 2007
    ..43, 95% CI, 1.18-5.03, P=0.016; 40-49 years: 4.22, 95% CI, 1.99-8.93, P<0.001; >or=50 years: 4.06, 95% CI, 1.69-9.78, P=0.002) and serum HBV DNA level>10(4) copies/ml (OR, 1.83; 95% CI, 1.07-3.13, P=0.027)...
  74. ncbi request reprint A prospective study characterizing full-length hepatitis B virus genomes during acute exacerbation
    Chun Jen Liu
    Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 1 Chang Te Street, Taipei 100, Taiwan
    Gastroenterology 124:80-90. 2003
    ..Hepatitis B virus (HBV) evolves rapidly in patients with chronic hepatitis B, and HBV variation may trigger acute exacerbation. To study this relationship, we investigated full-length viral sequences before, during, and after exacerbation...
  75. pmc Long-term effect of interferon plus ribavirin on hepatitis B surface antigen seroclearance in patients dually infected with hepatitis B and C viruses
    Ming Lun Yeh
    Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 6:e20752. 2011
    ..We aimed to investigate the rate of and the factors associated with HBsAg seroclearance during long-term follow-up after interferon-α/ribavirin combination therapy in HBV/HCV dually-infected patients...
  76. doi request reprint Clinical and histologic implications of delayed hepatobiliary enhancement on magnetic resonance imaging with gadolinium ethoxybenzyl diethylenetriaminepentaacetic Acid
    Bang Bin Chen
    Department of Radiology and Medical Imaging, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan
    Invest Radiol 47:649-55. 2012
    ....
  77. doi request reprint Functional impairment of dendritic cells in patients infected with hepatitis C virus genotype 1 who failed peginterferon plus ribavirin therapy
    Cheng Chao Liang
    Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan
    J Med Virol 83:1212-20. 2011
    ..The results suggest that low CD83 expression and high IL-10 production of DCs at the baseline may predict a poor virologic response to 24-week PEG-IFN plus ribavirin therapy in HCV genotype 1 patients...
  78. pmc Transient elastography to assess hepatic fibrosis in hemodialysis chronic hepatitis C patients
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Clin J Am Soc Nephrol 6:1057-65. 2011
    ..Using transient elastography (TE, Fibroscan(®)) to predict the severity of hepatic fibrosis has not been prospectively evaluated in these patients...
  79. ncbi request reprint Noninvasive diagnosis of hepatic fibrosis in patients with chronic hepatitis C by splenic Doppler impedance index
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Gastroenterol Hepatol 5:1199-1206.e1. 2007
    ..The value of Doppler ultrasonography to evaluate the severity of hepatic fibrosis in patients with chronic hepatitis C (CHC) remains controversial...
  80. ncbi request reprint Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma
    Chih Lin Lin
    Department of Gastroenterology, Ren Ai Branch, Taipei City Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 22:1098-103. 2007
    ..The correlation between pre-S deletion mutant and risk of hepatocellular carcinoma (HCC) in hepatitis B virus carriers remains unclear...
  81. doi request reprint Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma
    Jia Horng Kao
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Liver Int 32:1373-81. 2012
    ..Naturally occurring pre-S deletion mutants have been identified in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)...
  82. doi request reprint Association of hepatitis C virus infection and malnutrition-inflammation complex syndrome in maintenance hemodialysis patients
    Hung Bin Tsai
    Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
    Nephrol Dial Transplant 27:1176-83. 2012
    ..In the present study of Taiwanese MHD patients, we determined the clinical characteristics and influence of HCV infection on MICS by calculation of the malnutrition-inflammation score (MIS)...
  83. doi request reprint Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B
    Yi Wen Huang
    Liver Unit, Cathay General Hospital Medical Center, Taipei, Taiwan
    Antivir Ther 15:177-84. 2010
    ..In this study, we aimed to determine the detectability of serum HBV RNA during sequential combination therapy of interferon and lamivudine...
  84. ncbi request reprint Hepatitis B viral factors and clinical outcomes of chronic hepatitis B
    Chih Lin Lin
    Department of Gastroenterology, Ren Ai Branch, Taipei City Hospital, Taipei, Taiwan
    J Biomed Sci 15:137-45. 2008
    ..Further studies are needed to investigate the pathogenic mechanism of each viral factor...
  85. ncbi request reprint Hepatitis B virus-related hepatocellular carcinoma: epidemiology and pathogenic role of viral factors
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, R O C
    J Chin Med Assoc 70:141-5. 2007
    ..In this article, we thus review the epidemiology of HBV-related HCC and viral factors involved in hepatocarcinogenesis...
  86. doi request reprint Asymptomatic chronic hepatitis B virus infection does not increase the risk of diabetes mellitus: a ten-year observation
    Zei Shung Huang
    Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 25:1420-5. 2010
    ..We thus conducted this study to investigate the influence of asymptomatic chronic HBV infection on the incidence of diabetes in a longitudinal cohort...
  87. doi request reprint Human leukocyte antigen-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus
    Yi Wen Huang
    Liver Unit, Cathay General Hospital Medical Center, Taipei, Taiwan
    J Med Virol 81:588-93. 2009
    ..094). In male carriers harboring DRB1*1101, the distribution of hepatitis B viral genotype was comparable between the two groups. HLA-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus...
  88. doi request reprint Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects
    Jia Horng Kao
    Department of Internal Medicine, Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
    Adv Cancer Res 108:21-72. 2010
    ..In the future, through comprehensive and integrated approaches to analyze the genomes of human HCC, novel target genes or pathways critically involved in hepatocarcinogenesis may hopefully be identified...
  89. doi request reprint Aboriginal Taiwanese hepatitis B carriers have more favorable viral factors than Han Chinese carriers
    Hsiao Ching Nien
    Liver Disease Prevention and Treatment Research Foundation, Taipei, Taiwan
    J Med Virol 83:1326-31. 2011
    ..In conclusion, aboriginal Taiwanese HBV carriers have more favorable viral factors than Han Chinese carriers, which may be partly responsible for the lower standardized mortality rate of HCC in Taiwanese aborigines...
  90. ncbi request reprint Association of chronic hepatitis B virus infection with insulin resistance and hepatic steatosis
    Chia Chi Wang
    Division of Gastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan
    J Gastroenterol Hepatol 23:779-82. 2008
    ..The present study therefore aimed to investigate the association of chronic HBV infection with insulin resistance and hepatic steatosis...
  91. ncbi request reprint Hepatitis B viral genotype in Taiwanese patients with acute hepatitis B
    Yi Wen Huang
    Liver Unit, Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan
    Hepatogastroenterology 55:633-5. 2008
    ..The correlation of HBV genotype with clinical outcome has been recognized in chronic hepatitis B patients. However, there are few reports on the distribution and clinical significance of HBV genotypes in acute hepatitis B patients...
  92. doi request reprint Hepatitis B e antigen seroconversion: a critical event in chronic hepatitis B virus infection
    Yun Fan Liaw
    Liver Research Unit, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taipei, 105, Taiwan
    Dig Dis Sci 55:2727-34. 2010
    ..The importance of HBeAg seroconversion is underscored by current CHB treatment guidelines that recommend limiting the duration of antiviral therapy in HBeAg-positive patients who achieve seroconversion...
  93. doi request reprint The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism
    Ya Hui Tsai
    Graduate Institute of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan
    J Hepatol 49:899-907. 2008
    ..In this study, we investigated whether the non-structural 5A protein (NS5A) of HCV genotypes 1 and 2 (1b-NS5A and 2a-NS5A, respectively) exerted differential counteractivities against IFN treatment...
  94. ncbi request reprint Selective transmission of hepatitis C virus quasi species through a needlestick accident in acute resolving hepatitis
    Chen Hua Liu
    Department of Internal Medicine, National Taiwan University Hospital, Yun Lin branch, Taiwan
    Clin Infect Dis 42:1254-9. 2006
    ..Little is known about the transmission of variant hepatitis C virus (HCV) genome through needlestick injuries...
  95. ncbi request reprint Association of baseline viral factors with response to lamivudine therapy in chronic hepatitis B patients with high serum alanine aminotransferase levels
    Tai Chung Tseng
    Division of Hepatogastroenterology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital Taipei Branch, Taipei, Taiwan
    Antivir Ther 14:203-10. 2009
    ..We thus studied the influence of pre-therapy viral factors on end-of-treatment responses to lamivudine...
  96. doi request reprint Risk factors of hepatitis during anti-tuberculous treatment and implications of hepatitis virus load
    Jann Yuan Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taiwan
    J Infect 62:448-55. 2011
    ..We evaluate the risk factors of HATT and the clinical implications of serum viral loads in those with concomitant hepatitis B or C viruses (HBV/HCV) infection...
  97. ncbi request reprint Serum p53 gene polymorphisms and severity of hepatitis B or C-related chronic liver diseases in Taiwan
    Yone Han Mah
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Hepatol Int 5:814-21. 2011
    ..We aimed to investigate the impact of p53 polymorphisms on disease progression by evaluating their prevalence among chronic hepatitis B (CHB) or hepatitis C (CHC) patients with different stages of liver disease...
  98. ncbi request reprint Evolution of hepatitis B serological markers in HIV-infected patients receiving highly active antiretroviral therapy
    Wang Huei Sheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 45:1221-9. 2007
    ..Evolution of serological markers of hepatitis B virus (HBV) carriage or infection has rarely been investigated among human immunodeficiency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART)...
  99. ncbi request reprint Application of hepatitis B virus genotyping and phylogenetic analysis in intrafamilial transmission of hepatitis B virus
    Chih Lin Lin
    Department of Gastroenterology, Taipei City Hospital, Taipei, Taiwan
    Clin Infect Dis 41:1576-81. 2005
    ..Therefore, we used HBV genotyping and phylogenetic analysis to elucidate the modes of intrafamilial HBV transmission in Taiwan...
  100. ncbi request reprint Precore/core promoter mutations and genotypes of hepatitis B virus in chronic hepatitis B patients with fulminant or subfulminant hepatitis
    Chun Jen Liu
    Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taiwan
    J Med Virol 72:545-50. 2004
    ..In conclusion, the genomic variability of HBV does not seem to contribute to the fulminant and subfulminant exacerbation of chronic hepatitis B in Taiwanese HBV carriers...
  101. ncbi request reprint Two decades of universal hepatitis B vaccination in taiwan: impact and implication for future strategies
    Yen Hsuan Ni
    Department of Pediatrics, Hospital and College of Medicine, National Taiwan University, Genomics Research Center, Taipei, Taiwan
    Gastroenterology 132:1287-93. 2007
    ....