Jiiang Huei Jeng


Affiliation: National Taiwan University
Country: Taiwan


  1. Chang M, Lin S, Pan Y, Lin L, Wang Y, Yeung S, et al. IL-1β-induced ICAM-1 and IL-8 expression/secretion of dental pulp cells is differentially regulated by IRAK and p38. J Formos Med Assoc. 2018;: pubmed publisher
    ..Blocking of IRAKs and p38 signaling may have potential to control inflammation of dental pulp in the future. ..
  2. Chang M, Chen Y, Lian Y, Chang B, Huang C, Huang W, et al. Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells. Int J Mol Sci. 2018;19: pubmed publisher
    ..These effects are possibly related to increased histone acetylation. These events are important in the pathogenesis and repair of periodontal and periapical destruction. ..
  3. Liao W, Lee Y, Tsai Y, Lin H, Chang M, Chang S, et al. Outcome assessment of apical surgery: A study of 234 teeth. J Formos Med Assoc. 2018;: pubmed publisher
    ..These results provide more detailed information for the clinical practitioners to make treatment plans and are important for clinical endodontic practices. ..
  4. Yeh C, Chen H, Chang M, Kok S, Lee J, Chang B, et al. Cytotoxicity and transformation of C3H10T1/2 cells induced by areca nut components. J Formos Med Assoc. 2016;115:108-12 pubmed publisher
    ..ANE is an effective tumor initiator and can induce malignant transformation of C3H10T1/2 cells in the presence of a tumor promoter. ANE may be involved in multistep chemical carcinogenesis by its malignant transformation capacity. ..
  5. Lin S, Lin L, Chang H, Chang M, Wang Y, Pan Y, et al. IL-1β induced IL-8 and uPA expression/production of dental pulp cells: Role of TAK1 and MEK/ERK signaling. J Formos Med Assoc. 2018;117:697-704 pubmed publisher
    ..These events are associated with TAK1 and MEK/ERK signaling. Blocking of TAK1 and MEK/ERK signaling has potential to control inflammation of dental pulp. ..
  6. Yeh C, Lin C, Chang M, Chen H, Kok S, Chang S, et al. Differences in oral habit and lymphocyte subpopulation affect malignant transformation of patients with oral precancer. J Formos Med Assoc. 2016;115:263-8 pubmed publisher
    ..Analysis of patient's lymphocyte populations may help predict the malignant transformation of oral precancer. ..
  7. Chang M, Lin S, Lin L, Chan C, Lee M, Wang T, et al. Prostaglandin E2 Stimulates EP2, Adenylate Cyclase, Phospholipase C, and Intracellular Calcium Release to Mediate Cyclic Adenosine Monophosphate Production in Dental Pulp Cells. J Endod. 2016;42:584-8 pubmed publisher
    ..These results are helpful for understanding the role of PGE2 in pulpal inflammation and repair and possible future drug intervention. ..
  8. Chang H, Chang M, Wu I, Huang G, Huang W, Wang Y, et al. Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1-modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth. J Endod. 2015;41:1272-80 pubmed publisher
    ..These results highlight the future use of TGF-β1 and SCAP for engineering of pulpal regeneration and apexogenesis. ..
  9. Chang M, Tsai Y, Chang H, Lee S, Lee M, Chang C, et al. IL-1β-induced MCP-1 expression and secretion of human dental pulp cells is related to TAK1, MEK/ERK, and PI3K/Akt signaling pathways. Arch Oral Biol. 2016;61:16-22 pubmed publisher
    ..These events are related to differential activation of TAK1, PI3K/Akt and MEK/ERK 1/2 signaling and COX activation. These results are important for future pharmacologic intervention of pulpal inflammatory diseases. ..

More Information


  1. Lin P, Chang H, Yeh C, Chang M, Chan C, Kuo H, et al. Transforming growth factor beta 1 increases collagen content, and stimulates procollagen I and tissue inhibitor of metalloproteinase-1 production of dental pulp cells: Role of MEK/ERK and activin receptor-like kinase-5/Smad signaling. J Formos Med Assoc. 2017;116:351-358 pubmed publisher
    ..These events are associated with activin receptor-like kinase-5/Smad2/3 and MEK/ERK signaling. ..
  2. Liao W, Tsai Y, Wang C, Chang M, Huang W, Lin H, et al. Clinical and Radiographic Characteristics of Vertical Root Fractures in Endodontically and Nonendodontically Treated Teeth. J Endod. 2017;43:687-693 pubmed publisher
    ..These results elucidated some clinical and radiographic and diagnostic features that facilitate VRF identification. ..
  3. Chang Y, Chang M, Chen Y, Liou J, Chang H, Huang W, et al. Basic Fibroblast Growth Factor Regulates Gene and Protein Expression Related to Proliferation, Differentiation, and Matrix Production of Human Dental Pulp Cells. J Endod. 2017;43:936-942 pubmed publisher
    ..bFGF may be involved in pulpal repair and regeneration by activation of FGFRs to regulate cell growth; stimulate cdc2, cyclin B1, and TIMP-1 expression; and inhibit ALP. These events are partly associated with MEK/ERK signaling. ..
  4. Lin P, Cheng R, Chang M, Lee J, Chang H, Huang W, et al. TGF-?1 stimulates cyclooxygenase-2 expression and PGE2 production of human dental pulp cells: Role of ALK5/Smad2 and MEK/ERK signal transduction pathways. J Formos Med Assoc. 2017;116:748-754 pubmed publisher
    ..The effect of TGF-?1 on COX-2 protein expression was associated with ALK5/Smad2/3 and MEK/ERK pathways. These events are important in the early inflammation, repair and regeneration of dental pulp in response to injury. ..
  5. Jeng P, Luzi A, Pitarch R, Chang M, Wu Y, Jeng J. Cemental tear: To know what we have neglected in dental practice. J Formos Med Assoc. 2018;117:261-267 pubmed publisher
    ..Dentists should understand the predisposing factors and clinical features of cemental tears for early diagnosis/treatment to prevent bone loss/tooth extraction. ..