Tong Rong Jan

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. ncbi Diosgenin, a steroidal sapogenin, enhances antigen-specific IgG2a and interferon-gamma expression in ovalbumin-sensitized BALB/c mice
    Tong Rong Jan
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, ROC
    Planta Med 73:421-6. 2007
  2. ncbi Suppressive effects of cannabidiol on antigen-specific antibody production and functional activity of splenocytes in ovalbumin-sensitized BALB/c mice
    Tong Rong Jan
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, ROC
    Int Immunopharmacol 7:773-80. 2007
  3. ncbi Cannabidiol-induced apoptosis in primary lymphocytes is associated with oxidative stress-dependent activation of caspase-8
    Hsin Ying Wu
    Department of Veterinary Medicine, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, Taiwan 106, ROC
    Toxicol Appl Pharmacol 226:260-70. 2008
  4. ncbi Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity
    Chien Chang Shen
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei
    Int J Nanomedicine 7:2729-37. 2012
  5. ncbi A role of cellular glutathione in the differential effects of iron oxide nanoparticles on antigen-specific T cell cytokine expression
    Chien Chang Shen
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Int J Nanomedicine 6:2791-8. 2011
  6. ncbi A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells
    Chi Ya Lee
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Int Immunopharmacol 8:732-40. 2008
  7. ncbi Diosgenin, a plant-derived sapogenin, enhances regulatory T-cell immunity in the intestine of mice with food allergy
    Chung Hsiung Huang
    Department and Graduate Institute of Veterinary Medicine, National Taiwan University, Taipei, Taiwan 106, Republic of China
    J Nat Prod 73:1033-7. 2010
  8. ncbi Areca nut extracts enhance the development of CD11b(+) Gr-1(+) cells with the characteristics of myeloid-derived suppressor cells in antigen-stimulated mice
    Chia Chi Wang
    Animal Cancer Center, Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei
    J Oral Pathol Med 40:769-77. 2011
  9. ncbi Methamphetamine and diazepam suppress antigen-specific cytokine expression and antibody production in ovalbumin-sensitized BALB/c mice
    Shiaw Pyng Wey
    Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, ROC
    Toxicol Lett 181:157-62. 2008
  10. ncbi Silibinin attenuates antigen-specific IgE production through the modulation of Th1/Th2 balance in ovalbumin-sensitized BALB/c mice
    Fu Hua Kuo
    Department and Graduate Institute of Veterinary Medicine, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei 10617, Taiwan, ROC
    Phytomedicine 16:271-6. 2009

Collaborators

  • Mei Ping Kung
  • Chung Tien Lin
  • NORBERT EDWARD KAMINSKI
  • Aimen K Farraj
  • Chia Chi Wang
  • Hsin Ying Wu
  • Chien Chang Shen
  • Chung Hsiung Huang
  • Shiaw Pyng Wey
  • Mei Hsiu Liao
  • Der Zen Liu
  • Hong Jen Liang
  • Chi Ya Lee
  • Hung Li Lin
  • Yuh Feng Lin
  • Li En Hsieh
  • Cheng Hsiang Yao
  • Fu Hua Kuo
  • Tsung Yun Liu
  • Chiung Hsiang Cheng
  • Chi-Ya Lee
  • Hsin-Ying Wu
  • Yi Chun Huang
  • Rea Min Chu
  • Miriam Mecha
  • Kathleen Goble
  • Carmen Guaza
  • Pei Rong Jiang
  • Ming Chung Deng
  • Li Ping Tseng
  • Fang I Hsieh
  • Ing Tsung Hsiao
  • Kun Ju Lin
  • Daniel Skovronsky
  • Ling Ling Chueh
  • Tzu Chen Yen
  • Chi Min Chen
  • Bi Ling Su
  • Chieh min HU
  • Chi Chang Weng
  • Dah Sheng Lin
  • Ching Ho Wang
  • Yi Shu Ting
  • Chun Yao Ku
  • Pei Ling Huang
  • Shu-Hong Lin
  • Shiaw-Pyng Wey
  • Wei-Lun Hsu
  • Kuang Wen Liao
  • Yu Shan Wang
  • Chia-Chi Wang
  • Shao Wen Hung
  • Rea-Min Chu
  • Shu Hong Lin
  • Mei-Hsiu Liao
  • Wei Lun Hsu
  • Fang Chia Chang

Detail Information

Publications25

  1. ncbi Diosgenin, a steroidal sapogenin, enhances antigen-specific IgG2a and interferon-gamma expression in ovalbumin-sensitized BALB/c mice
    Tong Rong Jan
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, ROC
    Planta Med 73:421-6. 2007
    ....
  2. ncbi Suppressive effects of cannabidiol on antigen-specific antibody production and functional activity of splenocytes in ovalbumin-sensitized BALB/c mice
    Tong Rong Jan
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, ROC
    Int Immunopharmacol 7:773-80. 2007
    ....
  3. ncbi Cannabidiol-induced apoptosis in primary lymphocytes is associated with oxidative stress-dependent activation of caspase-8
    Hsin Ying Wu
    Department of Veterinary Medicine, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei, Taiwan 106, ROC
    Toxicol Appl Pharmacol 226:260-70. 2008
    ..Collectively, the present study demonstrated that the apoptotic effect of CBD in primary lymphocytes is closely associated with oxidative stress-dependent activation of caspase-8...
  4. ncbi Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity
    Chien Chang Shen
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei
    Int J Nanomedicine 7:2729-37. 2012
    ..The present study aimed to investigate the effect of iron oxide nanoparticles on delayed-type hypersensitivity (DTH), whose pathophysiology requires the participation of T helper 1 cells and macrophages...
  5. ncbi A role of cellular glutathione in the differential effects of iron oxide nanoparticles on antigen-specific T cell cytokine expression
    Chien Chang Shen
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Int J Nanomedicine 6:2791-8. 2011
    ..The present study investigates the direct effect of iron oxide nanoparticles on antigen-specific cytokine expression by T cells, and potential underlying mechanisms...
  6. ncbi A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells
    Chi Ya Lee
    Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Int Immunopharmacol 8:732-40. 2008
    ..The results demonstrated that both thymocytes and EL-4 thymoma cells were susceptible to CBD-induced apoptosis and that ROS played a critical role in the apoptosis induction...
  7. ncbi Diosgenin, a plant-derived sapogenin, enhances regulatory T-cell immunity in the intestine of mice with food allergy
    Chung Hsiung Huang
    Department and Graduate Institute of Veterinary Medicine, National Taiwan University, Taipei, Taiwan 106, Republic of China
    J Nat Prod 73:1033-7. 2010
    ..These results suggest that the suppressive effect of 1 on allergen-induced intestinal Th2 responses is closely associated with an up-regulation of the regulatory T-cell immunity in the inflammatory site...
  8. ncbi Areca nut extracts enhance the development of CD11b(+) Gr-1(+) cells with the characteristics of myeloid-derived suppressor cells in antigen-stimulated mice
    Chia Chi Wang
    Animal Cancer Center, Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei
    J Oral Pathol Med 40:769-77. 2011
    ..As areca nut extracts (ANE) have been reported to induce a proinflammatory effect in antigen-stimulated mice, we hypothesized that ANE might enhance the development of MDSC...
  9. ncbi Methamphetamine and diazepam suppress antigen-specific cytokine expression and antibody production in ovalbumin-sensitized BALB/c mice
    Shiaw Pyng Wey
    Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, ROC
    Toxicol Lett 181:157-62. 2008
    ..These results indicated that the central depressant diazepam did not affect methamphetamine-mediated immunosuppression. Rather, both drugs markedly suppressed antigen-specific antibody production and T-cell reactivity...
  10. ncbi Silibinin attenuates antigen-specific IgE production through the modulation of Th1/Th2 balance in ovalbumin-sensitized BALB/c mice
    Fu Hua Kuo
    Department and Graduate Institute of Veterinary Medicine, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei 10617, Taiwan, ROC
    Phytomedicine 16:271-6. 2009
    ..Together, these results suggest that silibinin treatment polarizes the Th1/Th2 immune balance toward the Th1-dominant direction, which may be beneficial against IgE-mediated allergy...
  11. ncbi Highly oligomeric procyanidins from areca nut induce lymphocyte apoptosis via the depletion of intracellular thiols
    Chia Chi Wang
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Toxicol In Vitro 23:1234-41. 2009
    ....
  12. ncbi A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice
    Chien Chang Shen
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei
    Int J Nanomedicine 6:1229-35. 2011
    ..The present study investigated the effect of iron oxide nanoparticles on antigen-specific immune responses in mice sensitized with the T cell-dependent antigen ovalbumin (OVA)...
  13. ncbi Areca-nut extract modulates antigen-specific immunity and augments inflammation in ovalbumin-sensitized mice
    Chia Chi Wang
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Immunopharmacol Immunotoxicol 33:315-22. 2011
    ..Taken together, these results demonstrated that ANE modulated antigen-specific immune responses and promoted inflammatory reactions in vivo, which may contribute to immune deregulation associated with areca-related diseases...
  14. ncbi Cannabidiol hydroxyquinone-induced apoptosis of splenocytes is mediated predominantly by thiol depletion
    Hsin Ying Wu
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, No 1 Sec 4 Roosevelt Road, Taipei, Taiwan, ROC
    Toxicol Lett 195:68-74. 2010
    ....
  15. ncbi Cannabidiol-induced apoptosis in murine microglial cells through lipid raft
    Hsin Ying Wu
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
    Glia 60:1182-90. 2012
    ..Taken together, these results suggest that CBD induces a marked proapoptotic effect in primary microglia through lipid raft coalescence and elevated expression of GM1 ganglioside and caveolin-1...
  16. ncbi Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity
    Der Zen Liu
    Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, Taipei, Taiwan, China
    Acta Pharmacol Sin 31:1611-7. 2010
    ..to investigate the effects cannabidiol (CBD) on delayed-type hypersensitivity (DTH) reactions and antigen-induced T-cell cytokine expression...
  17. ncbi Diosgenin attenuates allergen-induced intestinal inflammation and IgE production in a murine model of food allergy
    Chung Hsiung Huang
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    Planta Med 75:1300-5. 2009
    ..These results demonstrated the IN VIVO anti-allergic activity of diosgenin, which is associated with the suppression of IgE production and mast cell infiltration and degranulation...
  18. ncbi CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells
    Yi Chun Huang
    Animal Cancer Research Center, Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, 1 Roosevelt Road, Section 4, Taipei 106, Taiwan
    J Leukoc Biol 84:1501-10. 2008
    ..Taken together, the CD5lo subset in canine PBL is closely related to canine NK cells, and CD5lo can be used as a phenotypic marker for an IL-2-dependent canine NK cell enrichment...
  19. ncbi Involvement of the mitochondrion-dependent pathway and oxidative stress in the apoptosis of murine splenocytes induced by areca nut extract
    Chia Chi Wang
    Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, ROC
    Toxicol In Vitro 23:840-7. 2009
    ..Collectively, these results demonstrated the pro-apoptotic effect of ANE in primary lymphocytes, which was mediated, at least in part, by the activation of the mitochondrion-dependent pathway and oxidative stress...
  20. ncbi GMP-compliant automated synthesis of [(18)F]AV-45 (Florbetapir F 18) for imaging beta-amyloid plaques in human brain
    Cheng Hsiang Yao
    Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital, Taiwan, ROC
    Appl Radiat Isot 68:2293-7. 2010
    ..The specific activity of [(18)F]AV-45 reached as high as 470+/-135 TBq/mmol (n=19). The present studies show that [(18)F]AV-45 can be manufactured under GMP-compliant conditions and could be widely available for routine clinical use...
  21. ncbi Synergistic antiviral effect of Galanthus nivalis agglutinin and nelfinavir against feline coronavirus
    Li En Hsieh
    Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan
    Antiviral Res 88:25-30. 2010
    ..These results suggest that the combined use of GNA and nelfinavir has therapeutic potential in the prophylaxis and treatment of cats with early-diagnosed FIP...
  22. ncbi Adjuvant effect of liposome in chicken result from induction of nitric oxide
    Yuh Feng Lin
    Taipei Medical University Shuang Ho Hospital, Taiwan
    Biomed Mater 6:015011. 2011
    ..This finding may be useful for developing potent mucosal vaccine delivery systems in the future...
  23. ncbi Attenuation of the ovalbumin-induced allergic airway response by cannabinoid treatment in A/J mice
    Tong Rong Jan
    Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48824, USA
    Toxicol Appl Pharmacol 188:24-35. 2003
    ....
  24. ncbi Immune responses in the lung and local lymph node of A/J mice to intranasal sensitization and challenge with adjuvant-free ovalbumin
    Aimen K Farraj
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824, USA
    Toxicol Pathol 31:432-47. 2003
    ..The results of this study indicate that A/J mice intranasally instilled with ovalbumin without adjuvant have the hallmark histopathologic and immunologic features of IgE-mediated allergic airway disease of humans...
  25. ncbi Cannabinol enhancement of interleukin-2 (IL-2) expression by T cells is associated with an increase in IL-2 distal nuclear factor of activated T cell activity
    Tong Rong Jan
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824, USA
    Mol Pharmacol 61:446-54. 2002
    ..Collectively, these results suggest that increased IL-2 secretion by CBN is mediated through the enhancement of IL-2 gene transcription by activation of NF-AT in a CB1/CB2-independent manner...