Ching Yu Huang

Summary

Affiliation: National Health Research Institutes
Country: Taiwan

Publications

  1. pmc DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development
    Ching Yu Huang
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
    Eur J Immunol 42:476-88. 2012
  2. pmc DUSPs, to MAP kinases and beyond
    Ching Yu Huang
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, 35053, Taiwan
    Cell Biosci 2:24. 2012
  3. doi request reprint Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation
    Chia Yu Yang
    Immunology Research Center, National Health Research Institutes, Zhunan 35053, Taiwan
    J Immunol 192:1547-57. 2014
  4. pmc Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization
    Wan Yi Hsiao
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
    PLoS ONE 10:e0145880. 2015
  5. doi request reprint The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
    Huai Chia Chuang
    Immunology Research Center, National Health Research Institutes, Zhunan, Taiwan
    Nat Immunol 12:1113-8. 2011

Collaborators

  • Tse Hua Tan
  • Der Yuan Chen
  • Chia Yu Yang
  • Huai Chia Chuang
  • Wan Yi Hsiao
  • Ju Pi Li
  • Joung Liang Lan
  • Fang Hsuean Liao
  • Yi Chiao Chan
  • Yu Chun Lin
  • Li Li Chiu
  • Yi Ming Chen
  • Xiaohong Wang
  • Pao En Liu

Detail Information

Publications5

  1. pmc DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development
    Ching Yu Huang
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
    Eur J Immunol 42:476-88. 2012
    ..More importantly, our data indicate that DUSP4 suppresses CD4(+) T-cell proliferation through novel regulations in STAT5 phosphorylation and IL-2 signaling...
  2. pmc DUSPs, to MAP kinases and beyond
    Ching Yu Huang
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, 35053, Taiwan
    Cell Biosci 2:24. 2012
    ..Finally, we discuss briefly the potential roles of DUSPs in the regulation of non-MAP kinase targets, as well as in the modulation of tumorigenesis...
  3. doi request reprint Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation
    Chia Yu Yang
    Immunology Research Center, National Health Research Institutes, Zhunan 35053, Taiwan
    J Immunol 192:1547-57. 2014
    ..Thus, DUSP14 negatively regulates TCR signaling and immune responses by inhibiting TAB1 activation. ..
  4. pmc Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization
    Wan Yi Hsiao
    Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
    PLoS ONE 10:e0145880. 2015
    ..Our data thus provide the first genetic evidence that DUSP4 is important for helper T cell development. In addition, they also help uncover the novel, DUSP4-mediated regulation of STAT5 protein stability. ..
  5. doi request reprint The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
    Huai Chia Chuang
    Immunology Research Center, National Health Research Institutes, Zhunan, Taiwan
    Nat Immunol 12:1113-8. 2011
    ..Thus, GLK is a direct activator of PKC-θ, and activation of GLK-PKC-θ-IKK could be used as new diagnostic biomarkers and therapeutic targets for systemic lupus erythematosus...