Ching Yu Huang
Affiliation: National Health Research Institutes
- DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell developmentChing Yu Huang
Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
Eur J Immunol 42:476-88. 2012..More importantly, our data indicate that DUSP4 suppresses CD4(+) T-cell proliferation through novel regulations in STAT5 phosphorylation and IL-2 signaling...
- DUSPs, to MAP kinases and beyondChing Yu Huang
Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, 35053, Taiwan
Cell Biosci 2:24. 2012..Finally, we discuss briefly the potential roles of DUSPs in the regulation of non-MAP kinase targets, as well as in the modulation of tumorigenesis...
- The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cellsHuai Chia Chuang
Immunology Research Center, National Health Research Institutes, Zhunan, Taiwan
Nat Immunol 12:1113-8. 2011..Thus, GLK is a direct activator of PKC-θ, and activation of GLK-PKC-θ-IKK could be used as new diagnostic biomarkers and therapeutic targets for systemic lupus erythematosus...