Research Topics
Genomes and GenesSpecies | Chiun HsuSummaryAffiliation: National Taiwan University Country: Taiwan Publications
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Detail Information
Publications
Body size as a factor in different ages and breast cancer risk in TaiwanW C Chie
School of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan
Anticancer Res 18:565-70. 1998..The results of this study imply that adipose tissue may interfere with ovarian endocrine in the younger age group, and that there is increased hormonal production after obvious weight gain...
Quality of life of lung cancer patients: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-LC13Wei Chu Chie
School of Public Health and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Qual Life Res 13:257-62. 2004..The questionnaires could also detect expected adverse effects of radiotherapy, cisplatin, and paclitaxel...
Quality of life of breast cancer patients in Taiwan: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and EORTC QLQ-BR23Wei Chu Chie
School of Public Health and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taiwan
Psychooncology 12:729-35. 2003....
Quality of life in patients of nasopharyngeal carcinoma: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35W C Chie
School of Public Health and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Qual Life Res 12:93-8. 2003....
Oral contraceptives and breast cancer risk in Taiwan, a country of low incidence of breast cancer and low use of oral contraceptivesW C Chie
School of Public Health, College of Public Health, National Taiwan University, Taipei
Int J Cancer 77:219-23. 1998..Our results support the notion that OC use in early life for younger women and in early calendar years increase breast cancer risk...
Gemcitabine plus conventional-dose epirubicin versus gemcitabine plus cisplatin as first-line chemotherapy for stage IIIB/IV non-small cell lung carcinoma--a randomized phase II trialChiun Hsu
Department of Oncology, National Taiwan University Hospital, 7, Chung Shan South Road, Taipei, 100, Taiwan
Lung Cancer 62:334-43. 2008....
Multifractionated paclitaxel and cisplatin combined with 5-fluorouracil and leucovorin in patients with metastatic or recurrent esophageal squamous cell carcinomaChia Chi Lin
Department of Oncology, National Taiwan University, Taipei, Taiwan, ROC
Anticancer Drugs 18:703-8. 2007..3 and 8.9 months (range 1-50+), respectively. Twice-weekly TP-HDFL has the activity and toxicity profile similar to the previously reported same three-drug combination for advanced esophageal cancer...
A phase II trial of weekly paclitaxel and high-dose 5-fluorouracil plus leucovorin in patients with chemotherapy-pretreated metastatic breast cancerChia Chi Lin
Departments of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Anticancer Res 27:641-5. 2007..Weekly paclitaxel and infusional high-dose 5-fluorouracil/leucovorin (HDFL) are both effective regimens for metastatic breast cancer (MBC) patients...
Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinomaChih Hung Hsu
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
J Hepatol 53:126-31. 2010..This phase II study evaluated the efficacy and safety of combining metronomic tegafur/uracil with sorafenib in patients with advanced HCC...
Nuclear overexpression of mitotic regulatory proteins in biliary tract cancer: correlation with clinicopathologic features and patient survivalYing Chun Shen
Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan
Cancer Epidemiol Biomarkers Prev 18:417-23. 2009..Endogeneity testing suggested that nuclear overexpression of p53 and tumor type may influence patient survival through their interactions with Aurora-A/Aurora-B expression and tumor grade...
Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracilChao Yu Hsu
Department of Radiology, College of Medicine, National Taiwan University, Taipei, Taiwan
J Hepatol 55:858-65. 2011..This study evaluated the correlation of vascular response measured by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and the clinical outcome...
Phase II study of weekly paclitaxel and 24-hour infusion of high-dose 5-fluorouracil and leucovorin in the treatment of recurrent or metastatic gastric cancerKun-Huei Yeh
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Oncology 69:88-95. 2005..This paclitaxel-HDFL regimen is effective and well tolerated in the treatment of advanced gastric cancer...
Phase I study of biweekly gemcitabine followed by oxaliplatin and simplified 48-h infusion of fluorouracil/leucovorin for advanced pancreatic cancerChuan-Cheng Wang
Division of Cancer Research, National Health Research Institutes, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 21:874-9. 2006..3%, 95% confidence interval, 6.3-60.4%). CONCLUSION: Biweekly GOFL is a feasible regimen for advanced pancreatic cancer. For further phase II studies, the recommended dose of oxaliplatin is 85 mg/m2...
Inferior survival of advanced pancreatic cancer patients who received gemcitabine-based chemotherapy but did not participate in clinical trialsShih Hung Yang
Department of Oncology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan, ROC
Oncology 81:143-50. 2011..Advanced pancreatic cancer, even when treated, is highly lethal. The best choice of gemcitabine-based therapy and the prognostic factors affecting the success of treatment remain uncertain...
Outcome of advanced nonsmall cell lung cancer patients receiving gemcitabine and weekly paclitaxel as first-line treatmentZhong Zhe Lin
Department of Oncology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
Lung Cancer 60:215-21. 2008..Combinations of gemcitabine and paclitaxel with various doses and schedules were shown to be effective treatment for these patients. Nevertheless, the survival outcome of these patients is not clear...
Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cellsDa Liang Ou
National Center of Excellence for Clinical Trial and Research, Department of Oncology, National Taiwan University Hospital, Graduate Institute of Toxicology, Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan
Cancer Res 70:9309-18. 2010..Together, our findings suggest that GADD45β induction contributes to sorafenib-induced apoptosis in HCC cells, prompting further studies to validate its potential value in predicting sorafenib efficacy...
High circulating endothelial progenitor levels associated with poor survival of advanced hepatocellular carcinoma patients receiving sorafenib combined with metronomic chemotherapyYu Yun Shao
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, ROC
Oncology 81:98-103. 2011..We examined whether circulating endothelial progenitor (CEP) and circulating endothelial cell (CEC) levels had associations with the survival of patients who received antiangiogenic therapy for advanced hepatocellular carcinoma (HCC)...
Difference in the incidence trend of nasopharyngeal and oropharyngeal carcinomas in Taiwan: implication from age-period-cohort analysisChiun Hsu
Department of Oncology and Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, Taiwan
Cancer Epidemiol Biomarkers Prev 15:856-61. 2006..67 for men and 2.69 for women. Change in lifestyle seemed to be an important factor for the difference in the incidence trend between nasopharyngeal and oropharyngeal carcinomas and between men and women...
Predictive and prognostic values of tau and ERCC1 in advanced breast cancer patients treated with paclitaxel and cisplatinYu Yun Shao
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Jpn J Clin Oncol 40:286-93. 2010..We studied tau and excision repair cross-complementing 1 expression to evaluate their predictive values in advanced breast carcinoma patients...
Serum vascular endothelial growth factor/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancerYu Ting Chang
Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
Pancreas 37:145-50. 2008....
Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinomaYu Yun Shao
Department of Oncology, National Taiwan University Hospital, and Cancer Research Center, National Taiwan University School of Medicine, Taipei, Taiwan
Cancer 116:4590-6. 2010..In this study, the authors investigated levels of alpha-fetoprotein (AFP) as a potential biomarker for treatment efficacy of antiangiogenic therapy...
Molecular targeted therapy for advanced hepatocellular carcinoma: current status and future perspectivesYing Chun Shen
National Center of Excellence for Clinical Trial and Research, National Taiwan University Hospital, Taipei, Taiwan
J Gastroenterol 45:794-807. 2010..Patient selection according to the individual molecular signature of the tumor and correlative biomarker studies are encouraged while planning a clinical trial of novel MTT...
Factors impacting prognosis prediction in BCLC stage C and Child-Pugh class A hepatocellular carcinoma patients in prospective clinical trials of systemic therapyZhong Zhe Lin
Department of Oncology, National Taiwan University, Taipei, Taiwan
Oncologist 17:970-7. 2012..The purpose of this study was to determine the prognostic significance of clinical factors and staging systems for survival of hepatocellular carcinoma (HCC) patients who are candidates for therapeutic clinical trials...
Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinomaDa Liang Ou
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Clin Cancer Res 15:5820-8. 2009..This study explored whether the efficacy of sorafenib can be improved by adding the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK) inhibitor CI-1040 to vertically block the Raf/MEK/ERK pathway...
Survival outcome and predictors of gefitinib antitumor activity in East Asian chemonaive patients with advanced nonsmall cell lung cancerChih-Hsin Yang
Department of Oncology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
Cancer 107:1873-82. 2006..Female gender, adenocarcinoma histology, and nonsmoking status all were independent predictors of gefitinib response. The survival outcome of these patients was similar to that of patients who initially received chemotherapy...
A critical evaluation of the preventive effect of antiviral therapy on the development of hepatocellular carcinoma in patients with chronic hepatitis C or B: a novel approach by using meta-regressionYing Chun Shen
Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC
Oncology 82:275-89. 2012..The extent of the effect of antiviral therapy and its predictors in preventing hepatocellular carcinoma (HCC) development in patients with chronic hepatitis C (CHC) or B (CHB) remain unclear...
Survival of stage IIIB/IV non-small cell lung cancer patients who received chemotherapy but did not participate in clinical trialsSung-Hsin Kuo
Department of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung-Shan South Rd, Taipei, Taiwan
Lung Cancer 48:275-80. 2005..36; progression-free survival: P=0.57). Our data suggest that the survival of patients who received chemotherapy but did not participate in clinical trials was similar to patients participated in clinical trials...
Phase II study of combination doxorubicin, interferon-alpha, and high-dose tamoxifen treatment for advanced hepatocellular carcinomaYen-Shen Lu
Department of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Hepatogastroenterology 51:815-9. 2004..However, the data does not support that addition of interferon-alpha2b is superior to HTD regimen alone...
Diabetes mellitus is associated with increased mortality in patients receiving curative therapy for hepatocellular carcinomaWen Yi Shau
Division of Health Technology Assessment, Center for Drug Evaluation, Taipei, Taiwan
Oncologist 17:856-62. 2012..Diabetes mellitus (DM) is closely associated with hepatocarcinogenesis. This study explores the prognostic impact of DM in patients who received curative therapy for localized hepatocellular carcinoma (HCC)...
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathwayKuen Feng Chen
Department of Medical Research, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
J Biol Chem 284:11121-33. 2009..Together, bortezomib overcame TRAIL resistance at clinically achievable concentrations in hepatocellular carcinoma cells, and this effect is mediated at least partly via inhibition of the PI3K/Akt pathway...
Weekly cisplatin, infusional high-dose 5-fluorouracil and leucovorin for advanced, recurrent and metastatic cervical carcinomaSheng Mou Hsiao
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Pan Chiao, Taipei, Taiwan
Anticancer Res 28:1887-91. 2008....
Phase I-II trial of weekly gemcitabine plus high-dose 5-fluorouracil and leucovorin in advanced pancreatic cancerHer-Shyong Shiah
Division of Cancer Research, National Health Research Institutes, Veterans General Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 21:531-6. 2006..9 months, respectively. CONCLUSIONS: The GemFL24 regimen is a feasible and moderately active treatment with manageable toxicities for advanced pancreatic cancer, and could be a basis for further combination with other anticancer drugs...
Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): a meta-regression approachYing Chun Shen
Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan
J Hepatol 52:889-94. 2010..Adjuvant anti-viral therapy after curative therapy for HCC has been studied extensively but the true clinical benefit and the predictors of efficacy remain unclear...
Predictors of toxicity of weekly docetaxel in chemotherapy-treated non-small cell lung cancersJo Pai Chen
Department of Oncology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan
Lung Cancer 60:92-7. 2008..It should be given cautiously in elderly patients and in patients with chronic viral hepatitis or low white blood cell counts...
Vandetanib in patients with inoperable hepatocellular carcinoma: a phase II, randomized, double-blind, placebo-controlled studyChiun Hsu
Department of Oncology and Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
J Hepatol 56:1097-103. 2012..The present study evaluated the efficacy and safety of vandetanib, an oral inhibitor of both VEGFR and EGFR, in patients with unresectable advanced HCC...
Lack of efficacy to systemic chemotherapy for treatment of metaplastic carcinoma of the breast in the modern eraI C Chen
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Breast Cancer Res Treat 130:345-51. 2011..Tumor response to systemic chemotherapy remains generally poor for MCB patients. Taxanes may have modest activity, but need to be validated in further studies...
The Aurora kinase inhibitor VE-465 has anticancer effects in pre-clinical studies of human hepatocellular carcinomaZhong Zhe Lin
National Center of Excellence for Clinical Trial and Research, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan
J Hepatol 50:518-27. 2009..Recently, aberrant expression of Aurora kinases has been reported in various human cancers including HCC. We sought to investigate the potential of a potent and selective Aurora kinase inhibitor, VE-465, for targeted therapy of HCC...
Unexpected rapid progression of metastatic adenoid cystic carcinoma during treatment with imatinib mesylateChing-Hung Lin
Department of Oncology, National Taiwan University Hospital, National Taiwan University, No 7, Chung-Shan South Rd, Taipei 10016, Taiwan
Head Neck 27:1022-7. 2005..CONCLUSION: We observed an unexpected high progression rate of metastatic ACC within short periods during imatinib treatment. Use of imatinib to treat cancers without c-kit or PDGFR-alpha mutation should be approached with caution...
Issues and controversies of hepatocellular carcinoma-targeted therapy clinical trials in Asia: experts' opinionPei Jer Chen
National Taiwan University Hospital, Taipei, Taiwan
Liver Int 30:1427-38. 2010....
A revisit of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in non-Hodgkin's lymphoma: a randomized trialChiun Hsu
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Hepatology 47:844-53. 2008..CONCLUSION: Prophylactic lamivudine use, but not therapeutic use, reduces the incidence and severity of chemotherapy-related HBV reactivation in NHL patients...
Dose variation and regimen modification of adjuvant chemotherapy in daily practice affect survival of stage I-II and operable stage III Taiwanese breast cancer patientsSung Hsin Kuo
Department of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Breast 17:646-53. 2008..032) and OS (HR=0.54; P=0.025) than those treated with non-standard adjuvant chemotherapy. Breast cancer patients receiving standard adjuvant chemotherapy have a better DFS and OS than those receiving non-standard adjuvant chemotherapy...
ACCOMP: Augmented cell competition algorithm for breast lesion demarcation in sonographyJie Zhi Cheng
Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Number 1, Section 1, Jen Ai Road, Taipei 100, Taiwan
Med Phys 37:6240-52. 2010..This article aims to develop an image segmentation algorithm that provides quality delineation of breast lesions in sonography with a simple and friendly semiautomatic scheme...
The CYP19 TTTA repeat polymorphism is related to the prognosis of premenopausal stage I-II and operable stage III breast cancersChiun Sheng Huang
Department of Surgery, National Taiwan University Hospital, No 7, Chung Shan South Road, Taipei, Taiwan
Oncologist 13:751-60. 2008....
Overexpression of 14-3-3ε predicts tumour metastasis and poor survival in hepatocellular carcinomaBor Sheng Ko
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
Histopathology 58:705-11. 2011..However, it is not clear whether 14-3-3ε plays a role in tumour metastasis and patient outcome. The aim of this study was to determine whether 14-3-3ε is a marker for predicting hepatocellular carcinoma (HCC) metastasis and survival...
Significant difference in the trends of female breast cancer incidence between Taiwanese and Caucasian Americans: implications from age-period-cohort analysisYing-Chun Shen
Division of Medical Oncology and Hematology, Department of Internal Medicine, Far Eastern Memorial Hospital and Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan
Cancer Epidemiol Biomarkers Prev 14:1986-90. 2005..These findings indicate that a continued shift in the incidence and age distribution pattern of FIBC in Taiwanese toward that of Caucasian Americans should be anticipated...
Survival-weighted health profile for long-term survivors of acute myelogenous leukemiaChiun Hsu
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Qual Life Res 12:503-17. 2003..SWPS may be useful to evaluate the efficacy of different treatment strategies for AML. Confirmation of the relative merit of BMT vs. chemotherapy alone from prospective studies is needed...
Dynamic MRI signals in the second week of radiotherapy relate to treatment outcomes of hepatocellular carcinoma: a preliminary resultPo Chin Liang
Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
Liver Int 27:516-28. 2007..5 T before therapy, at 2 weeks of therapy, and 1 month (week 9) later. Initial first-pass enhancement slopes (slope) and peak enhancement ratios (peak) were measured...
Should adjuvant radiotherapy to the supraclavicular fossa be routinely given in patients with breast conservative treatment?Chun Wei Wang
Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
J Surg Oncol 96:144-50. 2007..To analyze the overall outcome, supraclavicular fossa (SCF) recurrence rate, and pattern of failure in breast cancer patients treated with conservative surgery and adjuvant radiotherapy excluding SCF treatment...
Phase II trial combining paclitaxel with 24-hour infusion cisplatin for chemotherapy-naïve patients with locally advanced or metastatic breast carcinomaChiun Hsu
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Cancer 95:2044-50. 2002..CONCLUSIONS: The combination of paclitaxel by 3-hour infusion and cisplatin by 24-hour infusion appears to be an active and well-tolerated regimen for chemotherapy-naïve patients with LABC or MBC...
Low-dose thalidomide treatment for advanced hepatocellular carcinomaChiun Hsu
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, ROC
Oncology 65:242-9. 2003..CONCLUSION: Low-dose thalidomide is safe and induces unequivocal tumor response in a minority of patients with advanced HCC...
Diagnostic value of 18F-FDG-PET/CT in indeterminate infiltrative hepatic lesions in an endemic area of viral hepatitisMei Fang Cheng
Department of Nuclear Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Nucl Med Commun 32:252-9. 2011....
Could Kinesio tape replace the bandage in decongestive lymphatic therapy for breast-cancer-related lymphedema? A pilot studyHan Ju Tsai
School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Zhongzheng District, Taipei 100, Taiwan, Republic of China
Support Care Cancer 17:1353-60. 2009....
Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: a multigenic study on cancer susceptibilityTing Chih Cheng
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Int J Cancer 113:345-53. 2005....
Clinicopathologic features and treatment outcome of non-Hodgkin lymphoma of the breast--a review of 42 primary and secondary cases in Taiwanese patientsYu Chin Lin
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Leuk Lymphoma 50:918-24. 2009..Further investigation of underlying mechanisms of young age- and stage IIE disease-related poor prognosis in patients with PBL is needed...
Molecular subtypes of breast cancer emerging in young women in Taiwan: evidence for more than just westernization as a reason for the disease in AsiaChing Hung Lin
Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
Cancer Epidemiol Biomarkers Prev 18:1807-14. 2009..As a first step to investigate the possible etiology, we examined the molecular subtypes of female breast cancer in Taiwan...
Radio-guided sentinel lymph node biopsy using periareolar injection technique for patients with early breast cancerRuoh Fang Yen
Department of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
J Formos Med Assoc 106:44-50. 2007..This study aimed to evaluate the accuracy of radio-guided sentinel LN (SLN) biopsy (SLNB) using the periareolar injection technique for predicting the histopathologic status of axillary LNs in early breast cancer patients...
Unique features of breast cancer in Asian women--breast cancer in Taiwan as an exampleChiun Sheng Huang
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
J Steroid Biochem Mol Biol 118:300-3. 2010..The frequency of the luminal-A subtype of breast cancer, characterized by estrogen receptor expression, is similar to that in breast cancer in Caucasian, supporting the usefulness of hormone-based therapy in Asian breast cancer...
Expression of the caudal-type homeodomain transcription factor CDX2 is related to clinical outcome in biliary tract carcinomaYu Ting Chang
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
J Gastroenterol Hepatol 22:389-94. 2007..The clinicopathological significance of CDX2 expression has hitherto remained unclear in biliary tract carcinoma (BTC). The aim of this study was to determine whether CDX2 expression in BTC indicates clinical outcome...
Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibilityJyh Cherng Yu
Departments of Surgery, Tri Service General Hospital, Taipei, Taiwan
J Biomed Sci 13:419-32. 2006..These epidemiological findings highlight the role of newly identified novel ER-related pathways in breast cancer development and provide a more comprehensive picture of the tumorigenic effect of estrogen in breast cancer development...
Comprehensive locoregional treatment and systemic therapy for postmastectomy isolated locoregional recurrenceSung Hsin Kuo
Department of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Int J Radiat Oncol Biol Phys 72:1456-64. 2008..To assess the impact of comprehensive locoregional therapy and systemic therapy on disease control and survival for postmastectomy patients with isolated locoregional recurrence (ILRR)...
Increased expression of SRp40 affecting CD44 splicing is associated with the clinical outcome of lymph node metastasis in human breast cancerChiun Sheng Huang
Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
Clin Chim Acta 384:69-74. 2007..Regulation of pre-mRNA splicing by serine-arginine (SR)-rich phosphoprotein is hypothesized to be associated with tumor cell metastasis...
Rapid image stitching and computer-aided detection for multipass automated breast ultrasoundRuey Feng Chang
Department of Computer Science and Information Engineering, Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan 10617
Med Phys 37:2063-73. 2010..In this study, an image stitching technique is proposed for combining multipass images of the whole breast into a series of full-view images, and a fully automatic screening system that works off these images is also presented...
