Shi Hong Gu

Summary

Affiliation: National Museum of Natural Science
Country: Taiwan

Publications

  1. Gu S, Yeh W, Young S, Lin P, Li S. TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2012;42:296-303 pubmed publisher
    ..These results suggest that PTTH/PI3K/TOR/4E-BP (S6K) signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in B. mori. ..
  2. Gu S, Lin P, Hsieh H. Bombyxin/Akt signaling in relation to the embryonic diapause process of the silkworm, Bombyx mori. J Insect Physiol. 2019;116:32-40 pubmed publisher
    ..mori eggs. To our knowledge, this is the first study to demonstrate the potential correlation between bombyxin/Akt signaling and the embryonic diapause process. ..
  3. Gu S, Chen C, Lin P, Hsieh H. Role of protein phosphatase 2A in PTTH-stimulated prothoracic glands of the silkworm, Bombyx mori. Gen Comp Endocrinol. 2019;274:97-105 pubmed publisher
    ..From these results, we hypothesize that PTTH-regulated PP2A signaling is a necessary component for the stimulation of ecdysteroidogenesis, potentially by mediating the link between ERK and TOR signaling pathways. ..
  4. Hsieh H, Gu S. Expression of calcineurin in relation to the embryonic diapause process in the silkworm, Bombyx mori. Comp Biochem Physiol A Mol Integr Physiol. 2019;228:35-42 pubmed publisher
    ..mori. ..
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    Gu S. Autocrine activation of DNA synthesis in prothoracic gland cells of the silkworm, Bombyx mori. J Insect Physiol. 2006;52:136-45 pubmed
    ..Injection of concentrated putative growth-promoting factor into day 4 last instar-ligated larvae greatly increased cell DNA synthesis of the prothoracic glands, indicating the in vivo function of the present autocrine factor. ..
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    Gu S. Autocrine activation of ecdysteroidogenesis in the prothoracic glands of the silkworm, Bombyx mori. J Insect Physiol. 2007;53:538-49 pubmed
  7. Gu S, Chen C, Hsieh Y, Lin P, Young S. Modulatory effects of bombyxin on ecdysteroidogenesis in Bombyx mori prothoracic glands. J Insect Physiol. 2015;72:61-9 pubmed publisher
    ..These results suggest that bombyxin modulates ecdysteroidogenesis in B. mori PGs during development. ..
  8. Gu S, Hsieh Y. Regulation of histone H3 phosphorylation at serine 10 in PTTH-stimulated prothoracic glands of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2015;57:27-33 pubmed publisher
    ..Taken together, these results suggest that PTTH-stimulated histone H3 phosphorylation at serine 10 is mediated by Ca(2+)/ERK signaling in B. mori PGs. ..
  9. Gu S, Lin J, Lin P, Chen C. Insulin stimulates ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2009;39:171-9 pubmed publisher
    ..These results suggest that in silkworm prothoracic glands, in addition to the PTTH and an autocrine factor, ecdysteroidogenesis is also stimulated by insulin during development...

More Information

Publications16

  1. Gu S, Lin J, Lin P. PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca(2+)/calmodulin and receptor tyrosine kinase. J Insect Physiol. 2010;56:93-101 pubmed publisher
  2. Gu S, Young S, Lin J, Lin P. Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2011;41:197-202 pubmed publisher
    ..mori prothoracic glands between insulin and PTTH signaling, which may play a critical role in precisely regulated ecdysteroidogenesis during development...
  3. Gu S, Young S, Tsai W, Lin J, Lin P. Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori. J Insect Physiol. 2011;57:978-85 pubmed publisher
    ..mori...
  4. Gu S, Hsieh Y, Lin P. Stimulation of orphan nuclear receptor HR38 gene expression by PTTH in prothoracic glands of the silkworm, Bombyx mori. J Insect Physiol. 2016;90:8-16 pubmed publisher
    ..The present study proposes a potential cross talk mechanism between PTTH and ecdysone signaling to regulate insect development and lays a foundation for a better understanding of the mechanisms of PTTH's actions. ..
  5. Gu S, Hsieh Y, Lin P. Signaling involved in PTTH-stimulated 4E-BP phosphorylation in prothoracic gland cells of Bombyx mori. J Insect Physiol. 2017;96:1-8 pubmed publisher
    ..Altogether, these results indicate interconnections among Ca2+ signaling, AMPK, and 4E-BP phosphorylation in PTTH-activated PGs of B. mori. ..
  6. Gu S, Hsieh H, Lin P. Regulation of protein phosphatase 2A during embryonic diapause process in the silkworm, Bombyx mori. J Insect Physiol. 2017;103:117-124 pubmed publisher
    ..These results demonstrate that the higher PP2A gene expression and PP2A A and B subunit protein levels and increased enzymatic activity are related to embryonic development of B. mori. ..
  7. Young S, Yeh W, Gu S. Transcriptional regulation of the PTTH receptor in prothoracic glands of the silkworm, Bombyx mori. J Insect Physiol. 2012;58:102-9 pubmed publisher