Research Topics
Genomes and Genes | Jen Hwey ChiuSummaryAffiliation: National Yang-Ming University Country: Taiwan Publications
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Detail Information
Publications
Electroacupuncture on PC6 (Neiguan) attenuates ischemia/reperfusion injury in rat heartsMeng-Ting Tsou
Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan
Am J Chin Med 32:951-65. 2004..05). We conclude that EA on bilateral PC6 (Neiguan) prevents and attenuates I/R injury to the heart, and that this approach may provide an applicable and preventative alternative for patients with ischemic heart disease...
Remote pharmacological preconditioning on median nerve territory increases Hsp32 expression and attenuates ischemia-reperfusion injury in rat heartJen Hwey Chiu
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taiwan, ROC
Life Sci 90:629-36. 2012..The aim of this study was to test the hypothesis that remote pharmacological preconditioning (RPP) induced myocardial heat shock protein (Hsp) 32 expression and attenuated the ischemia-reperfusion (I/R) injury of the heart in rats...
Different central manifestations in response to electroacupuncture at analgesic and nonanalgesic acupoints in rats: a manganese-enhanced functional magnetic resonance imaging studyJen Hwey Chiu
Institute of Traditional Medicine, National Yang Ming University, Number 155, Section 2, Li Nong Street, Peitou, Taipei, 112 Taiwan, Republic of China
Can J Vet Res 67:94-101. 2003....
Epimedium brevicornum Maxim extract relaxes rabbit corpus cavernosum through multitargets on nitric oxide/cyclic guanosine monophosphate signaling pathwayJ H Chiu
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Peitou, Taipei, Taiwan, ROC
Int J Impot Res 18:335-42. 2006..We concluded that extract of EbM relax the CC smooth muscle through multitargets in NO/cGMP/PDE 5 pathway and might bring into perspective the treatment strategy for those patients with erectile dysfunction...
Preconditioned somatothermal stimulation on median nerve territory increases myocardial heat shock protein 70 and protects rat hearts against ischemia-reperfusion injuryJen Hwey Chiu
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
J Thorac Cardiovasc Surg 125:678-85. 2003....
Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinomaAnn Ping Tsou
Institute of Biotechnology in Medicine, National Yang Ming University, Taipei, Taiwan
Oncogene 22:298-307. 2003..Taken together, these results strongly suggest that HURP is a potential novel cell cycle regulator that may play a role in the carcinogenesis of human cancer cells...
Trends in Chinese medicine use among prostate cancer patients under national health insurance in Taiwan: 1996-2008Yi Hsien Lin
Institute of Traditional Medicine, National Yang Ming University, Taipei, Taiwan, ROC
Integr Cancer Ther 10:317-27. 2011..Taiwan National Health Insurance (NHI) provides Western medicine and Chinese medicine (CM). This study aims to explore the trends of CM use among prostate cancer patients under NHI...
Quantification of electroacupuncture-induced neural activity by analysis of functional neural imaging with monocrystalline iron oxide nanocolloid enhancementShao Chang Ho
Institute of Traditional Chinese Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
Am J Chin Med 36:493-504. 2008..This study suggests that fMRI with AFNI is a good approach to quantifying brain activities. This innovative method brings new perspective into the mechanisms of acupuncture...
Effects of S/B remedy containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on hepatic interleukin-6 related signal transducer and activator of transcription 3 activation in mice through cell-cell interactionChang Yin Lee
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Japan
Biol Pharm Bull 34:727-33. 2011..The results provide important information on the molecular mechanisms of S/B remedy for treatment of human liver diseases...
Silibinin inhibits the invasion of IL-6-stimulated colon cancer cells via selective JNK/AP-1/MMP-2 modulation in vitroChiu Mei Lin
Department of Emergency Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
J Agric Food Chem 60:12451-7. 2012....
Effect of Epimedium brevicornum Maxim extract on elicitation of penile erection in the ratKuang Kuo Chen
Division of Urology, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Urology 67:631-5. 2006..To investigate the effect and mechanism of a Chinese medicine (Epimedium brevicornum Maxim [EbM]) on elicitation of penile erection in the rat...
Use of Chinese medicine by women with breast cancer: a nationwide cross-sectional study in TaiwanYi Hsien Lin
School of Medicine, National Yang Ming University, No 155 Sec 2 Li Nong St, Peitou, Taipei, Taiwan
Complement Ther Med 19:137-43. 2011..The National Health Insurance (NHI) provided Western medicine (WM) and Chinese medicine (CM) in Taiwan. This study aims to explore CM use by women with breast cancer under NHI...
Clinical response and autonomic modulation as seen in heart rate variability in mechanical intermittent cervical traction: a pilot studyPo Jung Pan
Department of Physical Medicine and Rehabilitation, National Yang Ming University Hospital, Taipei, Taiwan
J Rehabil Med 44:229-34. 2012..To determine the influence of mechanical intermittent cervical traction on the autonomic system...
Protective effects of preconditioned local somatothermal stimulation on neuromuscular plasticity against ischemia--reperfusion injury in ratsPo Jung Pan
Department of Physical Medicine and Rehabilitation, National Yang Ming University Hospital, Taiwan, Republic of China
J Orthop Res 26:1670-4. 2008....
Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamstersChang Yin Lee
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
Liver Int 28:841-55. 2008....
Overexpression of a novel imprinted gene, PEG10, in human hepatocellular carcinoma and in regenerating mouse liversAnn Ping Tsou
Institute of Biotechnology in Medicine, National Yang Ming University, Nankang, Taipei, Taiwan
J Biomed Sci 10:625-35. 2003..Understanding the molecular basis of the abnormal imprinting of PEG10 will shed new light on the process that leads to liver disease...
Use of Chinese medicine among prostate cancer patients in Taiwan: a retrospective longitudinal cohort studyYi Hsien Lin
Division of Radiotherapy, Cheng Hsin General Hospital, Taipei, Taiwan
Int J Urol 18:383-6. 2011..The increase of CM use over the first year of prostate cancer diagnosis can be primarily attributed to an increase of new CM users, rather than of CM visits per users...
Proteomic analysis finds different myocardial protective mechanisms for median nerve stimulation by electroacupuncture and by local somatothermal stimulationMeng-Ting Tsou
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, No. 155 Li-Nong Street Section 2, Taipei 112, Taiwan, R.O.C
Int J Mol Med 14:553-63. 2004..We conclude that MNS by either EA or LSTS attenuates I/R injury in rat hearts through different protective mechanisms and that EA and LSTS might provide an alternative treatment strategy for ischemic heart disease...
The role of oxidative stress response revealed in preconditioning heat stimulation in skeletal muscle of ratsPo Jung Pan
Department of Physical Medicine and Rehabilitation, National Yang Ming University Hospital, I Lan, Taiwan
J Surg Res 176:108-13. 2012....
Baicalein protects chicken embryonic cardiomyocyte against hypoxia-reoxygenation injury via mu- and delta- but not kappa-opioid receptor signalingI Hua Tu
Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, ROC
Eur J Pharmacol 588:251-8. 2008..We conclude that the cardioprotective effect of baicalein is mediated via mu-, delta- but not kappa-opioid receptor and their related signal transduction pathways, such as protein kinase C and the KATP channel...
Coprescription of Chinese Herbal Medicine and Western Medications among Prostate Cancer Patients: A Population-Based Study in TaiwanYi Hsien Lin
School of Medicine, National Yang Ming University, Taipei 112, Taiwan
Evid Based Complement Alternat Med 2012:147015. 2012..In conclusion, use of CHM among prostate cancer patients was popular in Taiwan. Most CHMs were used with WM concurrently. The potential drug-herb interactions should be investigated, especially for patients with more prescriptions...
Ferulic acid augments angiogenesis via VEGF, PDGF and HIF-1 alphaChiu Mei Lin
Department of Emergency Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
J Nutr Biochem 21:627-33. 2010..Taken together, ferulic acid serves as an angiogenic agent to augment angiogenesis both in vitro and in vivo. This effect might be observed through the modulation of VEGF, PDGF and HIF-1 alpha...
Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysinHao Wei Wang
Department of Surgery, Faculty of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan
Int J Cancer 120:2019-27. 2007..Further studies are warranted to evaluate wogonin and chrysin as a potential adjuvant therapy for drug-resistant NSCLC, especially for those with AKR1C1/1C2 overexpression...
1,3,5-trihydroxy-4-prenylxanthone represses lipopolysaccharide-induced iNOS expression via impeding posttranslational modification of IRAK-1Wen Fei Chiou
National Research Institute of Chinese Medicine, Taipei, Taiwan
Biochem Pharmacol 81:752-60. 2011....
Salvianolic acid B enhances in vitro angiogenesis and improves skin flap survival in Sprague-Dawley ratsIng-Shiow Lay
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C
J Surg Res 115:279-85. 2003..We conclude that Sal B attenuates ischemia-reperfusion injury of skin flap, and provides therapeutic potential in reconstructive plastic surgery...
The relationship of subjective sleep quality and cardiac autonomic nervous system in postmenopausal women with insomnia under auricular acupressureYen Ying Kung
Institute of Traditional Medicine, National Yang Ming University, Taipei, Taiwan
Menopause 18:638-45. 2011..The aim of this study is to examine the relationship between the changes in self-reported sleep symptoms and cardiac sympathovagal activity among women with postmenopausal insomnia (PI) who received auricular acupressure (AA) therapy...
Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activityHsueh Ping Chao
Institute of Traditional Medicine, National Yang Ming University, Taipei, Taiwan
Planta Med 76:1827-33. 2010..In summary, our results indicate that andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity...
Prevalence, patterns, and costs of Chinese medicine use among prostate cancer patients: a population-based study in TaiwanYi Hsien Lin
Institute of Traditional Medicine, corrected National Yang Ming University, Taipei, Taiwan corrected
Integr Cancer Ther 9:16-23. 2010..Taiwan's National Health Insurance (NHI) is a comprehensive and universal program, providing Western medicine (WM) and Chinese medicine (CM). This study aims to explore CM use among prostate cancer patients in NHI...
Protective mechanism of salvia miltiorrhiza on carbon tetrachloride-induced acute hepatotoxicity in ratsTzung-Yan Lee
Institute of Traditional Medicine, National Yang-Ming University School of Medicine, Taiwan
J Pharmacol Sci 91:202-10. 2003..This effect may be due to its ability to decrease the metabolic activation of CCl(4) by an increase in P450 2E1 protein content and its antioxidant activity associated with less increase in hepatic iNOS protein content...
Gene expression profiling predicts liver responses to a herbal remedy after partial hepatectomy in miceJir-You Wang
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Peitou, Taipei, 112 Taiwan, R.O.C
Int J Mol Med 16:221-31. 2005..We conclude that in vivo gene expression profiling correlates with liver responses to a herbal remedy, which provides a new direction for pharmaceutical studies on human diseases...
Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulationShung-Haur Yang
Institute of Clinical, Taipei, Taiwan, ROC
J Surg Res 128:140-6. 2005..CONCLUSION: We conclude that anti-angiogenic effects of SM/SB are associated with the up-regulation of VEGFR-1 (Flt-1) gene expression and that they are good candidates for combination therapy to treat colorectal cancer...
Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathwaysChiu-Mei Lin
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Planta Med 72:708-14. 2006..Besides, chrysin concentration-dependently inhibited the auto-regulation loop of IL-6/IL-6R in LPS-treated HUVEC cells. We conclude that chrysin suppresses both IN VITRO and IN VIVO LPS-induced angiogenesis...
Si-Wu-Tang and its constituents promote mammary duct cell proliferation by up-regulation of HER-2 signalingChun-Ju Chang
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Menopause 13:967-76. 2006..This provides important information for perimenopausal women who are at risk of or have breast cancer or other growths in breast tissue...
Enhancing effects of Scutellaria baicalensis and some of its constituents on TGF-beta1 gene expression in RAW 264.7 murine macrophage cell lineHan-Ning Chuang
Institute of Traditional Medicine, National Yang-Ming University, Taiwan, ROC
Planta Med 71:440-5. 2005..7 cells through NF-kappaB and PKC pathways and this might provide evidence to explain the therapeutic effect and potential adverse effects on the clinical use of Scutellaria baicalensis Georgi...
Crude extract of Salvia miltiorrhiza and salvianolic acid B enhance in vitro angiogenesis in murine SVR endothelial cell lineIng-Shiow Lay
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Planta Med 69:26-32. 2003..We conclude that the crude extract of SM and Sal B enhance angiogenic processes on SVR cells through up-regulation of VEGF and VEGF receptors genes...
Long-term administration of Salvia miltiorrhiza ameliorates carbon tetrachloride-induced hepatic fibrosis in ratsTzung-Yan Lee
Institute of Traditional Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
J Pharm Pharmacol 55:1561-8. 2003..In conclusion, long-term administration of Salvia miltiorrhiza in rats ameliorated the CCl4-induced hepatic injury that probably related to a reduced oxidant stress and degree of hepatic fibrosis...
Antiproliferation and radiosensitization of caffeic acid phenethyl ester on human medulloblastoma cellsYi-Hsien Lin
Institute of Traditional Medicine, National Yang-Ming University, 155. Sec. 2, Li-Nong St, Peitou, Taipei, 112, Taiwan
Cancer Chemother Pharmacol 57:525-32. 2006..CONCLUSIONS: These findings demonstrate the antiproliferative and radiosensitizing effects of CAPE for Daoy cells, which might bring improvement to the treatment of MB. For clinical application, in vivo models are expected...
Localization of cholecystokinin and vasoactive intestinal peptide in lower biliary tract in cats following electroacupuncture on right Qimen (LR14) and Riyue (GB 24): an immunohistochemistry studyYung-Ling Kuo
Institute of Chinese Medicine Science, China Medical College, Taichung, Taiwan, Republic of China
Acupunct Electrother Res 30:15-25. 2005..We conclude that EA regulates the biliary motility though increasing the distribution of CCK- and VIP-containing cells in duodenum and the sphincter of Oddi...
Effects of Scutellaria baicalensis Georgi on macrophage-hepatocyte interaction through cytokines related to growth control of murine hepatocytesJir-You Wang
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, 112 Taiwan, R.O.C
Exp Biol Med (Maywood) 231:444-55. 2006....
Chinese medicinal herbs Muh-Shiang Bin-Lang-Wan increases the motility of sphincter of Oddi in anesthetized rabbits through activation of M1 muscarinic receptorsYung-ing Kuo
Institute of Chinese Medicine Science, China Medical University, Taichung, Taiwan, ROC
Life Sci 74:533-42. 2003..We conclude that MSBLW is effective in increasing the SO motility in rabbits through activation of M1 muscarinic receptors. However, potential application of MSBLW in the treatment of human biliary disorders needs further evaluation...
Biological effect of far-infrared therapy on increasing skin microcirculation in ratsShi-Yau Yu
Institute of Molecular and Cellular Biology, Department of Life Science, National Tsing-Hua University, Hsinchu, and Division of General Surgery, Department of Surgery, Veterans General Hospital, Taipei, Taiwan
Photodermatol Photoimmunol Photomed 22:78-86. 2006..This might bring into perspective the clinical application of FIR to treat ischemic disease by augmenting L-arginine/NO pathway...
Preconditioned hyperbaric oxygenation protects the liver against ischemia-reperfusion injury in ratsShi-Yau Yu
School of Life Science, National Tsing-Hua University, Hsinchu, Taiwan
J Surg Res 128:28-36. 2005..Our results showed preconditioning by one-dose HBO protects rat liver against subsequent ischemia-reperfusion injury...
Water-soluble extract of Salvia miltiorrhiza ameliorates carbon tetrachloride-mediated hepatic apoptosis in ratsTzung-Yan Lee
Graduate Institute of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
J Pharm Pharmacol 58:659-65. 2006..miltiorrhiza extract. These results indicated that chronic administration of S. miltiorrhiza ameliorated CCl4-mediatd hepatic apoptosis in rats. This effect may be related to the antioxidant properties of S. miltiorrhiza...
Tumor necrosis factor-producing activity of wogonin in RAW 264.7 murine macrophage cell lineJen-Hwey Chiu
Planta Med 68:1036-9. 2002..We conclude that a low concentration of wogonin up-regulates NOS2 and TNF-alpha gene expression through NF-kappaB pathway...
