Lih Chu Chiou
Affiliation: National Taiwan University
Chiou L, Ling J, Chang C. Chinese herb constituent beta-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices. Neurosci Lett. 1997;231:171-4 pubmed
..5 microM)-induced electrographic seizure activity. The potential of beta-eudesmol to serve as an antiepileptic or a conjuvant in phenytoin therapy is suggested. ..
Chiou L, Liao Y, Fan P, Kuo P, Wang C, Riemer C, et al
. Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications. Curr Drug Targets. 2007;8:117-35 pubmed
..This review summarizes the pharmacological characteristics of, and studies with, the available NOP receptor ligands and their possible clinical implications. ..
Chiou L, Fan S, Chuang K, Liao Y, Lee S. Pharmacological characterization of nociceptin/orphanin FQ receptors, a novel opioid receptor family, in the midbrain periaqueductal gray. Ann N Y Acad Sci. 2004;1025:398-403 pubmed
..Our functional studies of NOP receptor ligands at native brain NOP receptors reveal that some of them act differently from those at expressed receptors of cell cultures. ..
Lu G, Lee C, Chiou L. Orexin A induces bidirectional modulation of synaptic plasticity: Inhibiting long-term potentiation and preventing depotentiation. Neuropharmacology. 2016;107:168-180 pubmed publisher
Chiou L, How C. ATP-sensitive K+ channels and cellular actions of morphine in periaqueductal gray slices of neonatal and adult rats. J Pharmacol Exp Ther. 2001;298:493-500 pubmed
..The correlation between the insensitivity in K+ channel activation and the less antinociceptive response to morphine in adults was discussed...