Yee Chun Chen

Summary

Affiliation: National Taiwan University
Country: Taiwan

Publications

  1. ncbi request reprint Treatment outcomes in patients receiving conventional amphotericin B therapy: a prospective multicentre study in Taiwan
    Chien Yuan Chen
    Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, Taiwan 100
    J Antimicrob Chemother 57:1181-8. 2006
  2. ncbi request reprint Adult methicillin-resistant Staphylococcus aureus bacteremia in Taiwan: clinical significance of non-multi-resistant antibiogram and Panton-Valentine leukocidin gene
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
    Diagn Microbiol Infect Dis 59:365-71. 2007
  3. doi request reprint Comparison of both clinical features and mortality risk associated with bacteremia due to community-acquired methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 46:799-806. 2008
  4. doi request reprint Influence of genospecies of Acinetobacter baumannii complex on clinical outcomes of patients with acinetobacter bacteremia
    Yu Chung Chuang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 52:352-60. 2011
  5. ncbi request reprint Community-onset candidemia at a university hospital, 1995-2005
    Hsiang Chi Kung
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 40:355-63. 2007
  6. pmc Clinical manifestations, laboratory findings, and treatment outcomes of SARS patients
    Jann Tay Wang
    National Taiwan University Hospital, Taipei, Taiwan
    Emerg Infect Dis 10:818-24. 2004
  7. ncbi request reprint Spinal epidural abscess due to Staphylococcus aureus: clinical manifestations and outcomes
    Wan Chin Chen
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital College of Medicine, Taipei, Taiwan
    J Microbiol Immunol Infect 41:215-21. 2008
  8. ncbi request reprint Trends and antimicrobial resistance of pathogens causing bloodstream infections among febrile neutropenic adults with hematological malignancy
    Chien Yuan Chen
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei
    J Formos Med Assoc 103:526-32. 2004
  9. ncbi request reprint Early empirical glycopeptide therapy for patients with methicillin-resistant Staphylococcus aureus bacteraemia: impact on the outcome
    Chi Tai Fang
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Antimicrob Chemother 57:511-9. 2006
  10. doi request reprint Microbiological and clinical characteristics of vancomycin-resistant Enterococcus faecium bacteraemia in Taiwan: implication of sequence type for prognosis
    Ching Lan Lu
    Department of Internal Medicine, National Taiwan University Hospital, Hsin Chu Branch, Hsin Chu, Taiwan
    J Antimicrob Chemother 67:2243-9. 2012

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Treatment outcomes in patients receiving conventional amphotericin B therapy: a prospective multicentre study in Taiwan
    Chien Yuan Chen
    Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, Taiwan 100
    J Antimicrob Chemother 57:1181-8. 2006
    ..To evaluate treatment outcomes and healthcare resource use with conventional amphotericin B therapy for invasive fungal infections (IFIs)...
  2. ncbi request reprint Adult methicillin-resistant Staphylococcus aureus bacteremia in Taiwan: clinical significance of non-multi-resistant antibiogram and Panton-Valentine leukocidin gene
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
    Diagn Microbiol Infect Dis 59:365-71. 2007
    ..Most PVL-positive MRSA isolates belonged to SCCmec V. PVL-positive CA-MRSA isolates could cause more deep-seated infections in patients presented with non-multi-resistant MRSA bacteremia...
  3. doi request reprint Comparison of both clinical features and mortality risk associated with bacteremia due to community-acquired methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 46:799-806. 2008
    ..No literature has been published on the clinical features and outcomes of adult patients with CA-MRSA bacteremia in comparison with patients with community-acquired methicillin-susceptible S. aureus (CA-MSSA) bacteremia...
  4. doi request reprint Influence of genospecies of Acinetobacter baumannii complex on clinical outcomes of patients with acinetobacter bacteremia
    Yu Chung Chuang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Infect Dis 52:352-60. 2011
    ..baumannii (genospecies 2) from other genospecies. Genospecies typing offers a potential tool to determine whether there are major differences in pathogenicity among the genospecies...
  5. ncbi request reprint Community-onset candidemia at a university hospital, 1995-2005
    Hsiang Chi Kung
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 40:355-63. 2007
    ..This retrospective study was conducted to describe predisposing factors and outcomes of community-onset candidemias...
  6. pmc Clinical manifestations, laboratory findings, and treatment outcomes of SARS patients
    Jann Tay Wang
    National Taiwan University Hospital, Taipei, Taiwan
    Emerg Infect Dis 10:818-24. 2004
    ..The overall case-fatality rate was 19.7%. By multivariate analysis, underlying disease and initial CRP level were predictive of death...
  7. ncbi request reprint Spinal epidural abscess due to Staphylococcus aureus: clinical manifestations and outcomes
    Wan Chin Chen
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital College of Medicine, Taipei, Taiwan
    J Microbiol Immunol Infect 41:215-21. 2008
    ..In this study, we describe the clinical features and outcomes of patients with spinal epidural abscess due to S. aureus...
  8. ncbi request reprint Trends and antimicrobial resistance of pathogens causing bloodstream infections among febrile neutropenic adults with hematological malignancy
    Chien Yuan Chen
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei
    J Formos Med Assoc 103:526-32. 2004
    ..The aim of this study was to clarify the trends and antimicrobial resistance among pathogens causing bloodstream infections in febrile neutropenic adults with hematological malignancies...
  9. ncbi request reprint Early empirical glycopeptide therapy for patients with methicillin-resistant Staphylococcus aureus bacteraemia: impact on the outcome
    Chi Tai Fang
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Antimicrob Chemother 57:511-9. 2006
    ..To evaluate whether appropriate early empirical glycopeptide therapy improves outcomes of patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia...
  10. doi request reprint Microbiological and clinical characteristics of vancomycin-resistant Enterococcus faecium bacteraemia in Taiwan: implication of sequence type for prognosis
    Ching Lan Lu
    Department of Internal Medicine, National Taiwan University Hospital, Hsin Chu Branch, Hsin Chu, Taiwan
    J Antimicrob Chemother 67:2243-9. 2012
    ..We aimed to examine whether there were newly introduced clones contributing to this increase and to assess the risk factors for mortality in patients with VREfm bacteraemia...
  11. ncbi request reprint Validation of a novel severe acute respiratory syndrome scoring system
    Chan Ping Su
    Department of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    Ann Emerg Med 43:34-42. 2004
    ..The objective of this study is to validate these scoring systems with a different set of patients...
  12. ncbi request reprint Predictive value of the serum bactericidal test for mortality in patients infected with multidrug-resistant Acinetobacter baumannii
    Chun Hsing Liao
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, 7 Chung Shan South Road, Taipei 100, Taiwan
    J Infect 55:149-57. 2007
    ..There are no standard tests to measure outcome in patients infected with these strains. Our aim was to determine whether a serum bactericidal test (SBT) could be used for this purpose...
  13. ncbi request reprint Longitudinal analysis of chlorhexidine susceptibilities of nosocomial methicillin-resistant Staphylococcus aureus isolates at a teaching hospital in Taiwan
    Jann Tay Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Antimicrob Chemother 62:514-7. 2008
    ..However, data on longitudinal surveillance of the susceptibility of MRSA isolates to chlorhexidine are limited...
  14. pmc Clinical and microbiological characteristics of perianal infections in adult patients with acute leukemia
    Chien Yuan Chen
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 8:e60624. 2013
    ..The epidemiology, microbiology, clinical manifestations and outcomes of perianal infection in leukemic patients are also rarely discussed...
  15. ncbi request reprint Changing characteristics of typhoid fever in Taiwan
    Chan Ping Su
    Department of Emergency Medicine, National Taiwan University Hospital, No 7 Chung Shan South Road, Taipei, Taiwan 100, ROC
    J Microbiol Immunol Infect 37:109-14. 2004
    ..It is important to include this disease in the differential diagnosis of febrile patients with abdominal symptoms...
  16. ncbi request reprint Septic Candida krusei thrombophlebitis of inferior vena cava with persistent fungemia successfully treated by new antifungal agents
    Sung Ching Pan
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Med Mycol 43:731-4. 2005
    ....
  17. ncbi request reprint Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome
    Wang Huei Sheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 104:715-23. 2005
    ..In order to elucidate the pathogenic mechanisms of SARS, we analyzed clinical manifestations and levels of serum cytokines of SARS patients...
  18. ncbi request reprint Community-acquired anaerobic bacteremia in adults: one-year experience in a medical center
    Min Nan Hung
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 38:436-43. 2005
    ..003), leukopenia (p=0.044) and absence of fever (p=0.047) were associated with mortality, only malignancy (p=0.007) was an independent risk factor in the multivariate analysis...
  19. ncbi request reprint Emerging fluoroquinolone-resistance for common clinically important gram-negative bacteria in Taiwan
    Wang Huei Sheng
    Section of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Diagn Microbiol Infect Dis 43:141-7. 2002
    ..Appropriate use of the new fluoroquinolones should be encouraged in order to prevent the rapid emergence and increase of fluoroquinolone-resistant bacteria...
  20. ncbi request reprint Molecular epidemiology and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus in Taiwan
    Jann Tay Wang
    Section of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Diagn Microbiol Infect Dis 42:199-203. 2002
    ..This might imply that more effort should be made to control the spread of MRSA in Taiwan...
  21. ncbi request reprint Species distribution and fluconazole susceptibility of Candida clinical isolates in a medical center in 2002
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC
    J Microbiol Immunol Infect 37:236-41. 2004
    ..However, the proportion of C. tropicalis increased from 14% during 1981-1993 to 22-23% during 1996-2002. Overall, the MIC50, MIC90 and the proportion of Candida blood isolates with fluconazole resistance remained stable during 1994-2002...
  22. pmc Infection control and SARS transmission among healthcare workers, Taiwan
    Yee Chun Chen
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
    Emerg Infect Dis 10:895-8. 2004
    ..Nonetheless, given that SARS has been highly transmissible on some occasions, we still recommend strict precautions...
  23. pmc Clinical characteristics and outcomes of Mycobacterium tuberculosis disease in adult patients with hematological malignancies
    Chien Yuan Chen
    Department of Internal Medicine, Division of Hematology, National TaiwanUniversity Hospital, Taipei, Taiwan
    BMC Infect Dis 11:324. 2011
    ..Diseases caused by Mycobacterium tuberculosis (TB) among adult patients with hematological malignancies have rarely been investigated...
  24. pmc Incidence of and risk factors for infection or colonization of vancomycin-resistant enterococci in patients in the intensive care unit
    Sung Ching Pan
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 7:e47297. 2012
    ..Strategies to reduce the duration of ICU stay and prudent usage of broad-spectrum antibiotics are the keys to controlling VRE transmission...
  25. ncbi request reprint Mycobacterium tuberculosis bacteremia in HIV-negative patients
    Yu Shin Chiu
    Division of Infectious Disease, Min Sheng General Hospital, Taoyuan, and Division of Infectious Disease, Department of Internal Medicine, Center for Infection Control, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 106:355-64. 2007
    ..Limited information exists about the epidemiologic characteristics of HIV-negative patients with Mycobacterium tuberculosis bacteremia (MTB)...
  26. pmc Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients
    Shan Chwen Chang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Clin Diagn Lab Immunol 12:1455-7. 2005
    ..The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive...
  27. ncbi request reprint Patient empowerment in a hand hygiene program: differing points of view between patients/family members and health care workers in Asian culture
    Sung Ching Pan
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Am J Infect Control 41:979-83. 2013
    ..Patient empowerment" is an important component of World Health Organization hand hygiene program, but little is known about the intentions and attitude of patients/families and health care workers (HCWs) regarding this...
  28. pmc SARS in hospital emergency room
    Yee Chun Chen
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
    Emerg Infect Dis 10:782-8. 2004
    ....
  29. ncbi request reprint Community-acquired bacteremic cellulitis caused by Acinetobacter baumannii
    Wen Chu Chiang
    Department of Emergency Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
    J Formos Med Assoc 102:650-2. 2003
    ..This case suggests that A. baumannii should be included among pathogens with the potential to cause complicated skin infection in the community...
  30. ncbi request reprint Survey of amphotericin B susceptibility of Candida clinical isolates determined by Etest
    Yu Shin Chiu
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 39:335-41. 2006
    ..We evaluated in vitro susceptibility of clinical isolates of Candida spp. to AmB using Etest and determined the distribution of AmB MICs in different species...
  31. doi request reprint Comparative in vitro antimicrobial susceptibilities and synergistic activities of antimicrobial combinations against carbapenem-resistant Acinetobacter species: Acinetobacter baumannii versus Acinetobacter genospecies 3 and 13TU
    Wang Huei Sheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
    Diagn Microbiol Infect Dis 70:380-6. 2011
    ..This knowledge will enable clinicians to select appropriate regimens for treating these infections...
  32. ncbi request reprint Impact of nosocomial infections on medical costs, hospital stay, and outcome in hospitalized patients
    Wang Huei Sheng
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 104:318-26. 2005
    ..The purpose of this study was to understand the economic and clinical impacts of nosocomial infections in Taiwan...
  33. doi request reprint Ertapenem in the treatment of bacteremia caused by extended-spectrum beta-lactamase-producing Escherichia coli: a propensity score analysis
    Un In Wu
    Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, 100, Taiwan
    Int J Infect Dis 16:e47-52. 2012
    ..This study assessed the impact of ertapenem and other carbapenems on mortality in patients with monomicrobial extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) bacteremia...
  34. ncbi request reprint Control of an outbreak of pandrug-resistant Acinetobacter baumannii colonization and infection in a neonatal intensive care unit
    Pei Chun Chan
    Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
    Infect Control Hosp Epidemiol 28:423-9. 2007
    ..To investigate the potential reservoir and mode of transmission of pandrug-resistant (PDR) Acinetobacter baumannii in a 7-day-old neonate who developed PDR A. baumannii bacteremia that was presumed to be the iceberg of a potential outbreak...
  35. ncbi request reprint Stable susceptibility of Candida blood isolates to fluconazole despite increasing use during the past 10 years
    Yee Chun Chen
    Department of Internal Medicine, National Taiwan University Hospital No 7, and College of Medicine, National Taiwan University, Taipei, Taiwan
    J Antimicrob Chemother 52:71-7. 2003
    ..These include low prevalence of C. krusei and C. glabrata, changing patterns of use of antifungal drugs and broad-spectrum antibiotics, and efforts to improve the rational use of antifungal agents at our hospital...
  36. pmc Distribution of Staphylococcal cassette chromosome mec Types and correlation with comorbidity and infection type in patients with MRSA bacteremia
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan
    PLoS ONE 5:e9489. 2010
    ..However, there is little information regarding the clinical features and outcomes of bacteremia patients with MRSA carrying different SCCmec types...
  37. pmc Detection of circulating galactomannan in serum samples for diagnosis of Penicillium marneffei infection and cryptococcosis among patients infected with human immunodeficiency virus
    Yu Tsung Huang
    Department of Internal Medicine, National Taiwan University Hospital, No 7 Chung Shan South Road, Taipei 100, Taiwan
    J Clin Microbiol 45:2858-62. 2007
    ..The use of the GM antigen assay may facilitate earlier diagnosis of Penicillium marneffei infection for HIV-infected patients in areas of endemicity...
  38. ncbi request reprint The usefulness of the Platelia Candida antigen in a patient with acute lymphocytic leukemia and chronic disseminated candidiasis
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Med Mycol 44:647-50. 2006
    ..Anti-mannan antibody remained undetectable up to 164 days after first positive blood culture despite the patient's recovery from neutropenia and recruitment of neutrophils in the tissue (skin)...
  39. pmc Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan
    Chien Yuan Chen
    Department of Internal Medicine, Division of Hematology, National Taiwan University Hospital, Taipei, Taiwan
    BMC Infect Dis 11:250. 2011
    ..Risk factors and outcomes in hematological patients who acquire invasive fungal sinusitis (IFS) are infrequently reported in the modern medical era...
  40. pmc Comparison of an automated repetitive-sequence-based PCR microbial typing system with pulsed-field gel electrophoresis for molecular typing of vancomycin-resistant Enterococcus faecium
    Yu Chung Chuang
    Department of Internal Medicine, National Taiwan University Hospital, No 7 Chung Shan South Road, Taipei, Taiwan
    J Clin Microbiol 48:2897-901. 2010
    ..PFGE remains the preferred method to confirm clonal spread...
  41. pmc Primary liver abscess caused by one clone of Klebsiella pneumoniae with two colonial morphotypes and resistotypes
    Po Ren Hsueh
    Department of Laboratory Medicine, National Taiwan University Hospital, No 7 Chung Shan South Road, Taipei, Taiwan
    Emerg Infect Dis 8:100-2. 2002
    ..Primary liver abscess caused by second-generation cephalosporin-resistant K. pneumoniae strains may be an emerging problem in Taiwan...
  42. pmc Safety and efficacy of high-dose daptomycin as salvage therapy for severe gram-positive bacterial sepsis in hospitalized adult patients
    Chung Chih Lai
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    BMC Infect Dis 13:66. 2013
    ..Increasing the dosage of daptomycin may be advantageous in severe infection by enhancing bactericidal activity and pharmacodynamics. However, clinical data on using daptomycin at doses above 6 mg/kg in Asian population are limited...
  43. ncbi request reprint A prospective study of antimicrobial-related adverse drug reactions in hospitalized patients
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 41:151-9. 2008
    ..The present study aimed to assess the incidence, risk factors, clinical manifestations, and causative agents of antimicrobial-ADRs in hospitalized patients...
  44. pmc Effectiveness of tigecycline-based versus colistin- based therapy for treatment of pneumonia caused by multidrug-resistant Acinetobacter baumannii in a critical setting: a matched cohort analysis
    Yu Chung Chuang
    Department of Internal Medicine, National Taiwan University Hospital, NO, 7 Chung Shan South Road, Taipei 100, Taiwan
    BMC Infect Dis 14:102. 2014
    ..Colistin and tigecycline have both been shown good in vitro activity among multi-drug resistant Acinetobacter baumannii (MDRAB). A comparative study of colistin versus tigecycline for MDRAB pneumonia is lacking...
  45. ncbi request reprint Identification of a novel protein 3a from severe acute respiratory syndrome coronavirus
    Chia Jung Yu
    Department of Medical Research, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei 100, Taiwan
    FEBS Lett 565:111-6. 2004
    ..Our study demonstrates that SARS-CoV indeed expresses a novel protein 3a, which is present only in SARS-CoV and not in other known CoVs...
  46. ncbi request reprint Fever of unknown origin: a retrospective study of 78 adult patients in Taiwan
    Keh Sen Liu
    Section of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC
    J Microbiol Immunol Infect 36:243-7. 2003
    ..In conclusion, infection remains the most important cause of classic FUO in Taiwan, confirming the findings in previous series. The importance of tuberculosis and AIDS as frequent causes of FUO should be emphasized...
  47. ncbi request reprint Community-onset Escherichia coli and Klebsiella pneumoniae bacteremia: influence of health care exposure on antimicrobial susceptibility
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Diagn Microbiol Infect Dis 55:135-41. 2006
    ..coli strains than those without hospital exposure within the previous year. However, no difference in resistance was observed in K. pneumoniae isolates from patients in different clinical settings...
  48. doi request reprint Factors associated with development of complications among adults with influenza: a 3-year prospective analysis
    Un In Wu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 111:364-9. 2012
    ..This prospective study aimed to describe the clinical features, as well as outcomes, of adult patients with influenza of different severity, and to determine the predictors for development of complications...
  49. pmc Compliance of health care workers with hand hygiene practices: independent advantages of overt and covert observers
    Sung Ching Pan
    Center for Infection Control, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 8:e53746. 2013
    ..Covert observation offers the opportunity to decrease observer bias. In this study we conducted a one year hospital-wide HH promotion program that included medical students (MS) as covert observers...
  50. doi request reprint Bacteremia in previously hospitalized patients: prolonged effect from previous hospitalization and risk factors for antimicrobial-resistant bacterial infections
    Shey Ying Chen
    Department of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    Ann Emerg Med 51:639-46. 2008
    ..Our objectives are to determine the time from previous hospital discharge that affects subsequent antimicrobial susceptibility pattern and risk factors for antimicrobial-resistant infection in bacteremia in recently discharged patients...
  51. ncbi request reprint Assessing the thoroughness of hand hygiene: "Seeing is believing"
    Sung Ching Pan
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan
    Am J Infect Control 42:799-801. 2014
    ..6%), followed by fingertips (17.4%). This stress-free "seeing is believing" program can encourage HCWs' active participation in sustaining the HH culture of health care institutions. ..
  52. ncbi request reprint Impacts of a mass vaccination campaign against pandemic H1N1 2009 influenza in Taiwan: a time-series regression analysis
    Un In Wu
    Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Zhongzheng District, Taipei 100, Taiwan
    Int J Infect Dis 23:82-9. 2014
    ....
  53. ncbi request reprint Comparison of epidemiology and treatment outcome of patients with candidemia at a teaching hospital in Northern Taiwan, in 2002 and 2010
    Pao Yu Chen
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan Center for Infection Control, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 47:95-103. 2014
    ....
  54. doi request reprint Medical students' perceptions of their role as covert observers of hand hygiene
    Sung Ching Pan
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    Am J Infect Control 42:231-4. 2014
    ..This report describes the students' experience and their views of the major factors that led to good or poor compliance...
  55. doi request reprint Combination antifungal therapy for disseminated fusariosis in immunocompromised patients : a case report and literature review
    Jyh You Liu
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Med Mycol 49:872-8. 2011
    ..Among 19 published cases in the last 10 years plus this patient, the patients in 14 cases (70%) responded positively to combination antifungal therapy. A clinical response was achieved in seven cases before resolution of neutropenia...
  56. pmc Effectiveness and limitations of hand hygiene promotion on decreasing healthcare-associated infections
    Yee Chun Chen
    Center for Infection Control, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 6:e27163. 2011
    ..We use a quasi-experimental, before and after, study design with prospective hospital-wide surveillance of HAIs to assess the cost effectiveness of HHPs...
  57. doi request reprint Changing epidemiology of nosocomial bloodstream infections in 11 teaching hospitals in Taiwan between 1993 and 2006
    Chia Ying Liu
    Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 43:416-29. 2010
    ..To understand the changing epidemiology of nosocomial bloodstream infections (BSI) in Taiwan, we retrospectively collected nosocomial infection data from 11 hospitals and examined the trends and changing patterns of nosocomial BSI...
  58. doi request reprint Changing incidence and clinical manifestations of Clostridium difficile-associated diarrhea detected by combination of glutamate dehydrogenase and toxin assay in Northern Taiwan
    Yi Chieh Lee
    Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 45:287-95. 2012
    ..This prospective study evaluates the incidence and clinical manifestation of CDAD following a hospital-wide hand hygiene promotion program in a 2,200-bed teaching hospital in northern Taiwan...
  59. doi request reprint Molecular epidemiology and antifungal susceptibility of Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis in Taiwan
    Yee Chun Chen
    Division of Infectious Diseases, Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Diagn Microbiol Infect Dis 68:284-92. 2010
    ..orthopsilosis and C. metapsilosis isolates expressed the isoleucine to valine substitution on the hot spot 2 region. However, the amino acid variations in these isolates did not correlate to their MIC values of echinocandin...
  60. doi request reprint In vitro activity of linezolid, tigecycline, and daptomycin on methicillin-resistant Staphylococcus aureus blood isolates from adult patients, 2006-2008: stratified analysis by vancomycin MIC
    Tsui Mai Kao
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 44:346-51. 2011
    ....
  61. ncbi request reprint Cryptococcus neoformans peritonitis in two patients with liver cirrhosis
    Shio Shin Jean
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 104:39-42. 2005
    ..Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis...
  62. pmc Association between contaminated faucets and colonization or infection by nonfermenting gram-negative bacteria in intensive care units in Taiwan
    Jiun Ling Wang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Clin Microbiol 47:3226-30. 2009
    ..The electrokaryotypes of four clinical isolates of C. meningosepticum were similar to those of faucet isolates. Measures directed at making the water supply safe may prevent infection by C. meningosepticum and other waterborne pathogens...
  63. ncbi request reprint Using 18-fluoro-2-deoxyglucose positron emission tomography in detecting infectious endocarditis/endoarteritis: a preliminary report
    Ruoh Fang Yen
    Department of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No 7, Chung Shan South Road, Taipei 10016, Taiwan
    Acad Radiol 11:316-21. 2004
    ..We evaluated the effectiveness of positron emission tomography (PET) with 18-fluoro-2-deoxyglucose (FDG) in the detection of infectious endocarditis/endoarteritis...
  64. ncbi request reprint Predictive model of antimicrobial-resistant gram-negative bacteremia at the ED
    Wen Chu Chiang
    Department of Emergency Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
    Am J Emerg Med 25:597-607. 2007
    ....
  65. doi request reprint Severity of pandemic H1N1 2009 influenza virus infection may not be directly correlated with initial viral load in upper respiratory tract
    Un In Wu
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Influenza Other Respir Viruses 6:367-73. 2012
    ..We hypothesized that viral load in upper respiratory specimens obtained on presentation may not be correlated with disease severity...
  66. doi request reprint Prospective randomized study of efficacy of 1-day versus 3-day antibiotic prophylaxis for preventing surgical site infection after coronary artery bypass graft
    Mei Hsin Lin
    Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 110:619-26. 2011
    ..This study compared the efficacy of 1-day versus 3-day antibiotic prophylaxis in preventing surgical site infection (SSI) in patients undergoing coronary artery bypass graft (CABG)...
  67. ncbi request reprint Successful treatment of imported cerebral malaria with artesunate-mefloquine combination therapy
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University Hospital, Yun Lin branch, and National Taiwan University College of Medicine, Taipei, Taiwan, R O C
    J Formos Med Assoc 105:86-9. 2006
    ..The only adverse event associated with artesunate was transient reticulocytopenia, which resolved after discontinuation of therapy. Her vision completely recovered, along with renal and liver function...
  68. doi request reprint Performance of the BD GeneOhm methicillin-resistant Staphylococcus aureus (MRSA) PCR assay for detecting MRSA nasal colonization in Taiwanese adults
    Wei Ting Chen
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 43:372-7. 2010
    ....
  69. doi request reprint Cluster of parvovirus infection among hospital staff working in coronary care units
    Yee Chun Chen
    Department of Internal Medicine, National Taiwan University Hospital, Taiwan
    J Formos Med Assoc 109:886-94. 2010
    ..The virus is relatively conserved and nucleotide identity is expected in viruses that are epidemiologically related. Here, we describe the first cluster of parvovirus infection among hospital staff documented in Taiwan...
  70. doi request reprint Clinical presentations, laboratory results and outcomes of patients with Kikuchi's disease: emphasis on the association between recurrent Kikuchi's disease and autoimmune diseases
    Chien Yu Cheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 43:366-71. 2010
    ..Kikuchi's disease (KD), also known as histiocytic necrotizing lymphadenitis, is a benign and self-limiting disease of unknown etiology that mainly affects young women. There is limited data on the long-term prognosis of patients with KD...
  71. doi request reprint Risk factors for bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli
    Un In Wu
    Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, Taiwan
    J Microbiol Immunol Infect 43:310-6. 2010
    ..A case-control study was undertaken to identify the risk factors associated with bloodstream infections caused by ESBL producing E. coli...
  72. doi request reprint Causes, clinical symptoms, and outcomes of infectious diseases associated with hemophagocytic lymphohistiocytosis in Taiwanese adults
    Yu Tzu Tseng
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 44:191-7. 2011
    ..Few systematic reviews have been published on the clinical manifestations, causes, and indicators for prognosis of HLH caused by infections...
  73. doi request reprint Certainties and uncertainties facing emerging respiratory infectious diseases: lessons from SARS
    Yee Chun Chen
    Department of Internal Medicine, and Center for Infection Control, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, Taiwan
    J Formos Med Assoc 107:432-42. 2008
    ..Herein, we relate our perspective on useful lessons derived from a review of the SARS epidemic that may be useful to physicians, especially when looking ahead to the next epidemic...
  74. doi request reprint Human immunodeficiency virus testing among patients with tuberculosis at a university hospital in Taiwan, 2000 to 2006
    Hsiang Chi Kung
    Department of Internal Medicine, National Taiwan University Hospital, Yun Lin branch, Yun Lin, Taiwan
    J Formos Med Assoc 108:320-7. 2009
    ..This study assessed the frequency and results of HIV testing among patients diagnosed with TB at a university hospital from 2000 to 2006...
  75. doi request reprint Infections occurring during extracorporeal membrane oxygenation use in adult patients
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    J Thorac Cardiovasc Surg 140:1125-32.e2. 2010
    ..The application of extracorporeal membrane oxygenation in adults has been increasing, but infections occurring during extracorporeal membrane oxygenation use are rarely described...
  76. ncbi request reprint Characteristics and outcomes of community-onset septic arthritis in adults
    Yu Chung Chuang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 42:258-64. 2009
    ..This study compared the demographic characteristics, risk factors, and outcomes of patients with community-onset septic arthritis due to Gram-positive and Gram-negative bacteria...
  77. ncbi request reprint Differential secretion of Sap4-6 proteins in Candida albicans during hyphae formation
    Yee Chun Chen
    Section of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Microbiology 148:3743-54. 2002
    ..This study provides the first evidence that Sap4-6 proteins in C. albicans are differentially produced and secreted during hyphae formation...
  78. doi request reprint Safety and efficacy of intravenous colistin (colistin methanesulphonate) for severe multidrug-resistant Gram-negative bacterial infections
    Chien Yu Cheng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Int J Antimicrob Agents 35:297-300. 2010
    ..Clinical outcomes are associated with the severity of infection and underlying diseases. Compared with previous reports, this study showed a lower incidence of nephrotoxicity and neurotoxicity...
  79. doi request reprint The first case of severe novel H1N1 influenza successfully rescued by extracorporeal membrane oxygenation in Taiwan
    Tsui Mai Kao
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 108:894-8. 2009
    ..Hospital course was uneventful and he was discharged 26 days after transfer to Hospital B. This experience showed that ECMO can be life-saving for severe novel H1N1 infection...
  80. doi request reprint Identification of distinct ciprofloxacin susceptibility in Acinetobacter spp. by detection of the gyrA gene mutation using real-time PCR
    Wang Huei Sheng
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Mol Cell Probes 23:154-6. 2009
    ..5 degrees C. The assay can rapidly and accurately identify the mutated QRDR of gyrA gene in CipR Acinetobacter spp., and potentially increase the rate of the appropriate therapy for Acinetobacter infections...
  81. pmc Staphylococcal cassette chromosome mec in MRSA, Taiwan
    Jann Tay Wang
    National Taiwan University Hospital, Taipei, Taiwan, Republic of China
    Emerg Infect Dis 13:494-7. 2007
    ..We found a shift from type IV to type III SCCmec element during 1992-2003, perhaps caused by selective pressure from indiscriminate use of antimicrobial drugs...
  82. ncbi request reprint Functional characterization and localization of acetyl-CoA hydrolase, Ach1p, in Saccharomyces cerevisiae
    Leh Miauh Buu
    Institute of Molecular Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, 7 Chung Shan South Road, Taipei 100, Taiwan
    J Biol Chem 278:17203-9. 2003
    ..We infer that Ach1p may be involved in a novel acetyl-CoA biogenesis and/or acetate utilization in mitochondria and thereby indirectly affect pseudohyphal development in yeast...
  83. ncbi request reprint In vitro activities of 16 antimicrobial agents against clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in two regional hospitals in Taiwan
    Chun Hsing Liao
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 39:59-66. 2006
    ..Local knowledge of antimicrobial susceptibilities of these organisms is important for implementation of effective hospital anti-infective policies...
  84. ncbi request reprint Clinical experience of 17 cases of imported malaria at a Taiwan university hospital, 1999-2005
    Hsing Chun Chung
    Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    J Microbiol Immunol Infect 40:209-15. 2007
    ..Malaria had been eradicated in Taiwan since 1965, but there are currently 30 to 50 imported cases annually. The management of imported malaria continues to be challenging due to evolving drug resistance of Plasmodium parasites...