Jeffrey S Chang

Summary

Affiliation: National Health Research Institutes
Country: Taiwan

Publications

  1. pmc Medical risk factors associated with cholangiocarcinoma in Taiwan: a population-based case-control study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    PLoS ONE 8:e69981. 2013
  2. doi request reprint Allergy and risk of childhood acute lymphoblastic leukemia: a population-based and record-based study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    Am J Epidemiol 176:970-8. 2012
  3. doi request reprint Medically diagnosed infections and risk of childhood leukaemia: a population-based case-control study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC
    Int J Epidemiol 41:1050-9. 2012
  4. doi request reprint The role of alcohol dehydrogenase genes in head and neck cancers: a systematic review and meta-analysis of ADH1B and ADH1C
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan Republic of China
    Mutagenesis 27:275-86. 2012
  5. pmc FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia
    Patrick Chang
    Department of Epidemiology and Biostatistics, UCSF, Helen Diller Cancer Research Building, San Francisco, CA 94158, USA
    BMC Cancer 10:513. 2010
  6. pmc Profound deficit of IL10 at birth in children who develop childhood acute lymphoblastic leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94143 0520, USA
    Cancer Epidemiol Biomarkers Prev 20:1736-40. 2011
  7. pmc Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 19:2152-63. 2010
  8. pmc Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, Division of Neuroepidemiology, University of California San Francisco, San Francisco, CA 94143 1215, USA
    Carcinogenesis 30:78-87. 2009
  9. pmc Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia
    Catherine Metayer
    School of Public Health, University of California, Berkeley, 1995 University Avenue, Suite 460, Berkeley, CA 94704 7392, USA
    Cancer Causes Control 22:1243-58. 2011
  10. doi request reprint Maternal immunoglobulin E and childhood leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94143 1215, USA
    Cancer Epidemiol Biomarkers Prev 18:2221-7. 2009

Collaborators

Detail Information

Publications30

  1. pmc Medical risk factors associated with cholangiocarcinoma in Taiwan: a population-based case-control study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    PLoS ONE 8:e69981. 2013
    ..This study utilized a population-based case-control design using data from the National Health Insurance Research Database (NHIRD) of Taiwan to assess the medical conditions associated with cholangiocarcinoma...
  2. doi request reprint Allergy and risk of childhood acute lymphoblastic leukemia: a population-based and record-based study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    Am J Epidemiol 176:970-8. 2012
    ..3, 95% CI: 1.1, 1.5), and before the age of 1 year (OR = 1.4, 95% CI: 1.1, 1.7). These results suggest that the pathogenesis of childhood ALL and allergy share a common biologic mechanism...
  3. doi request reprint Medically diagnosed infections and risk of childhood leukaemia: a population-based case-control study
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC
    Int J Epidemiol 41:1050-9. 2012
    ..The current study used a population-based and record-based case-control design to evaluate the association between childhood leukaemia and infections using the National Health Insurance Research Database of Taiwan...
  4. doi request reprint The role of alcohol dehydrogenase genes in head and neck cancers: a systematic review and meta-analysis of ADH1B and ADH1C
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan Republic of China
    Mutagenesis 27:275-86. 2012
    ..These results underscore the importance of ADH1B and ADH1C in the association between alcohol consumption and the risk for HNC...
  5. pmc FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia
    Patrick Chang
    Department of Epidemiology and Biostatistics, UCSF, Helen Diller Cancer Research Building, San Francisco, CA 94158, USA
    BMC Cancer 10:513. 2010
    ..The causes and timing of the mutations are not currently known. We evaluated the prevalence and timing of origin of FLT3 mutations in a population series of childhood leukemia patients from Northern California...
  6. pmc Profound deficit of IL10 at birth in children who develop childhood acute lymphoblastic leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94143 0520, USA
    Cancer Epidemiol Biomarkers Prev 20:1736-40. 2011
    ..The current study examines the association between neonatal cytokine profiles, a proxy measure for a child's prenatal immune development, and childhood ALL...
  7. pmc Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 19:2152-63. 2010
    ..The lack of immune priming in early childhood may result in abnormal immune responses to infections later in life and increase ALL risk...
  8. pmc Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, Division of Neuroepidemiology, University of California San Francisco, San Francisco, CA 94143 1215, USA
    Carcinogenesis 30:78-87. 2009
    ..This study suggests that there are genetic differences in the association between BER pathway and lung cancer between Latinos and African-Americans...
  9. pmc Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia
    Catherine Metayer
    School of Public Health, University of California, Berkeley, 1995 University Avenue, Suite 460, Berkeley, CA 94704 7392, USA
    Cancer Causes Control 22:1243-58. 2011
    ..We examined whether child's germline genetic variation in the folate pathway is associated with childhood acute lymphoblastic leukemia (ALL), and whether periconception maternal folate and alcohol intake modify the risk...
  10. doi request reprint Maternal immunoglobulin E and childhood leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94143 1215, USA
    Cancer Epidemiol Biomarkers Prev 18:2221-7. 2009
    ....
  11. pmc Allergies and risk of head and neck cancer: an original study plus meta-analysis
    Jenn Ren Hsiao
    Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    PLoS ONE 8:e55138. 2013
    ..It is not clear whether allergies can independently influence the risk of HNC in the presence of known strong environmental risk factors, including consumption of alcohol, betel quid, and cigarette...
  12. pmc SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system
    Alexander R Pico
    Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 37:D803-9. 2009
    ..We have found integration of SNP annotation in the context of pathway information and functional prediction scores to be a powerful approach to the analysis and interpretation of SNP-disease association data...
  13. pmc NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis
    Neela Guha
    Division of Epidemiology, School of Public Health, University of California, Berkeley, California 94704, USA
    Am J Epidemiol 168:1221-32. 2008
    ..Therefore, further research is warranted on the role of NQO1 polymorphisms in the etiology of childhood leukemia, especially among MLL-positive leukemias...
  14. pmc Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA
    Int J Cancer 123:2095-104. 2008
    ..61; 95% CI: 0.42-0.88). Our study suggests different elements of the NER pathway may be important in the different ethnic groups resulting either from different linkage relationship, genetic backgrounds and/or exposure histories...
  15. doi request reprint Investigating the association between oral hygiene and head and neck cancer
    Jeffrey S Chang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    Oral Oncol 49:1010-7. 2013
    ....
  16. pmc Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies
    Kyle M Walsh
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Genet Epidemiol 37:222-8. 2013
    ..These results highlight that the deficiencies of the candidate-gene approach lay in selecting both appropriate genes and relevant SNPs within these genes...
  17. doi request reprint Allergies and childhood leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, 44 Page Street, University of California San Francisco, San Francisco, CA 94143 1215, USA
    Blood Cells Mol Dis 42:99-104. 2009
    ..In addition, the utilities of genetic and molecular studies to disentangle the association between allergies and childhood leukemia and to elucidate the biological mechanisms are also discussed...
  18. doi request reprint Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, 44 Page Street, Suite 503, San Francisco, CA 94143 1215, USA
    Cancer Epidemiol Biomarkers Prev 17:1368-73. 2008
    ..Despite less than complete inclusion of genes and SNPs relevant to glioma and a small sample size, RF analysis identified one important biological pathway and several SNPs potentially associated with the development of glioblastoma...
  19. pmc Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
    Margaret Wrensch
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
    Nat Genet 41:905-8. 2009
    ..85 x 10(-10). On 20q13.3, rs6010620 intronic to RTEL1 had discovery P = 1.5 x 10(-7), replication P = 0.00035 and combined P = 3.40 x 10(-9). For both SNPs, the direction of association was the same in discovery and replication phases...
  20. pmc The epidemiology of neuroendocrine tumors in Taiwan: a nation-wide cancer registry-based study
    Hui Jen Tsai
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    PLoS ONE 8:e62487. 2013
    ..The epidemiology of neuroendocrine tumors (NETs) is not well illustrated, particularly for Asian countries...
  21. pmc Second cancers in patients with neuroendocrine tumors
    Hui Jen Tsai
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e86414. 2013
    ..In this nationwide population-based study, we used data recorded by the Taiwan Cancer Registry (TCR) to analyze the incidence and distribution of second cancers after the diagnosis of NETs...
  22. pmc Tobacco smoke exposure and the risk of childhood acute lymphoblastic and myeloid leukemias by cytogenetic subtype
    Catherine Metayer
    School of Public Health, University of California, 1995 University Avenue, Suite 460, Berkeley, CA94704 7392, USA
    Cancer Epidemiol Biomarkers Prev 22:1600-11. 2013
    ....
  23. ncbi request reprint Parental smoking and the risk of childhood leukemia
    Jeffrey S Chang
    School of Public Health, University of California, Berkeley, CA 94720 7380, USA
    Am J Epidemiol 163:1091-100. 2006
    ..004). These results strongly suggest that exposure to paternal preconception smoking alone or in combination with postnatal passive smoking may be important in the risk of childhood leukemia...
  24. pmc Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia
    Joseph L Wiemels
    Laboratory for Molecular Epidemiology, Department of Epidemiology and Biostatistics, and Helen Diller Comprehensive Cancer Center, University of California San Francisco, CA 94158, USA
    Blood Cells Mol Dis 45:186-91. 2010
    ..We posit a natural history for hyperdiploid leukemia in which prenatal mitotic catastrophe is followed by a postnatal RAS mutation to produce the leukemic cell phenotype...
  25. doi request reprint Parental smoking and childhood leukemia
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
    Methods Mol Biol 472:103-37. 2009
    ..g., asthma, respiratory tract infection, and otitis media) that are much more prevalent than childhood leukemia...
  26. doi request reprint The epidemiology of gastrointestinal stromal tumors in Taiwan, 1998-2008: a nation-wide cancer registry-based study
    Nai Jung Chiang
    National Institute of Cancer Research, National Health Research Institutes, 2 F, NO, 367, Sheng Li Road, Tainan 70456, Taiwan
    BMC Cancer 14:102. 2014
    ..To investigate the incidence of gastrointestinal stromal tumors (GISTs) in Taiwan and the impact of imatinib on the overall survival (OS) of GIST patients...
  27. doi request reprint Arginine deprivation as a new treatment strategy for head and neck cancer
    Cheng Chih Huang
    Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Oral Oncol 48:1227-35. 2012
    ..Argininosuccinate synthetase (ASS) is the rate-limiting enzyme for de novo arginine production. The expression pattern of ASS and the feasibility of arginine deprivation therapy in head and neck cancer have not been investigated...
  28. doi request reprint Differences in the frequencies of K-ras c12-13 genotypes by gender and pathologic phenotypes in colorectal tumors measured using the allele discrimination method
    Lihui Chow
    National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan
    Environ Mol Mutagen 53:22-31. 2012
    ..Using this method, we demonstrate differences in the frequencies of K-ras genotypes by gender and pathologic phenotypes of CRC...
  29. ncbi request reprint Breast cancer and dietary factors in Taiwanese women
    Marion M Lee
    Department of Epidemiology and Biostatistics, University of California at San Francisco, MU 420 West, San Francisco, CA 94143 0560, USA
    Cancer Causes Control 16:929-37. 2005
    ..To examine the effect of the consumption of dietary factors on the risk of breast cancer in a case-control study in Taiwan...
  30. doi request reprint Phase II study of concomitant thalidomide during radiotherapy for hepatocellular carcinoma
    Hui Ju Ch'ang
    National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    Int J Radiat Oncol Biol Phys 82:817-25. 2012
    ..The objective of the present study was to determine whether the combined treatment of thalidomide with radiotherapy (RT) is associated with acceptable toxicity and an improved clinical outcome in HCC patients...