Research Topics
| Chih Jen ChangSummaryAffiliation: National Cheng Kung University Country: Taiwan Publications
| Collaborators
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Detail Information
Publications
Multiple mechanisms of GW-9508, a selective G protein-coupled receptor 40 agonist, in the regulation of glucose homeostasis and insulin sensitivityHorng Yih Ou
Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
Am J Physiol Endocrinol Metab 304:E668-76. 2013..Taken together, GW-9508 exerts a partial agonist effect to regulate blood glucose through multiple mechanisms. Investigation of chemicals that act on GPR40 might be a new strategy for the treatment of diabetes...- Increased fetuin-A concentrations in impaired glucose tolerance with or without nonalcoholic fatty liver disease, but not impaired fasting glucoseHorng Yih Ou
Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, Tainan 70403, Taiwan
J Clin Endocrinol Metab 97:4717-23. 2012..Both prediabetes and NAFLD are associated with increased cardiovascular risk, and their concurrence significantly impairs hepatic and adipose tissue insulin sensitivity... - Increased arterial stiffness in subjects with impaired glucose tolerance and newly diagnosed diabetes but not isolated impaired fasting glucoseChung Hao Li
Department of Family Medicine, National Cheng Kung University Hospital, 138 Sheng Li Road, Tainan, 70441 Taiwan, Republic of China
J Clin Endocrinol Metab 97:E658-62. 2012..Studies have shown that diabetes mellitus increased brachial-ankle pulse-wave velocity (baPWV), but the impact of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) remains controversial... 
Epidemiological evidence of increased bone mineral density in habitual tea drinkersChih Hsing Wu
Department of Family Medicine, National Cheng Kung University Hospital, 138 Sheng Li Rd, Tainan 70428, Taiwan
Arch Intern Med 162:1001-6. 2002..Hence, the relationship between habitual tea consumption and BMD is an interesting issue...- Low body mass index but high percent body fat in Taiwanese subjects: implications of obesity cutoffsC J Chang
Department of Family Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Int J Obes Relat Metab Disord 27:253-9. 2003..The corresponding BF% to BMI cutoffs of overweight and obesity will also be studied... 
The evaluation of a Taiwanese training program in smoking cessation and the trainees' adherence to a practice guidelineFei Ran Guo
Division of Geriatric Research, Institute of Population Health Sciences, Department of Family Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan
BMC Public Health 10:77. 2010..The program certified 6,009 physicians till 2007. The objective of this study is to evaluate the short- and long term efficacy of the training program...- In addition to obesity and insulin resistance, microalbuminuria and diminished insulin secretion are linked with the metabolic syndrome in community-dwelling nondiabetic Taiwanese subjectsYi Ching Yang
Department of Family Medicine, College of Medicine, National Cheng Kung University, 138 Sheng Li Rd, Tainan 704, Taiwan, ROC
Diabetes Res Clin Pract 76:102-10. 2007..Inadequate beta-cell function and microalbuminuria are plausible components of the metabolic syndrome in Taiwanese subjects... - Epidemiological evidence of altered cardiac autonomic function in subjects with impaired glucose tolerance but not isolated impaired fasting glucoseJin Shang Wu
Department of Family Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan, 70441, Taiwan, Republic of China
J Clin Endocrinol Metab 92:3885-9. 2007.... - Sleep duration is a potential risk factor for newly diagnosed type 2 diabetes mellitusChi Yuan Chao
Department of Family Medicine, Min Sheng General Hospital, Ching Kuo Campus, Taoyuan, Taiwan
Metabolism 60:799-804. 2011..83 (1.19-6.73), respectively. However, sleep duration was not found to relate to prediabetes. In conclusion, both short and long sleep durations were independently associated with newly diagnosed diabetes, but not with prediabetes... - Epidemiological study on the effect of pre-hypertension and family history of hypertension on cardiac autonomic functionJin Shang Wu
Department of Family Medicine, National Cheng Kung University, Taiwan, Republic of China
J Am Coll Cardiol 51:1896-901. 2008..This study sought to examine the hypothesis that cardiac autonomic function (CAF) is altered in pre-hypertensive subjects and normotensive subjects with a family history of hypertension (FHH)... - Endoplasmic reticulum stress induces the expression of fetuin-A to develop insulin resistanceHorng Yih Ou
Department of Internal Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan 70403, Taiwan
Endocrinology 153:2974-84. 2012..Moreover, ER stress induced by high glucose and palmitate increased the expression of fetuin-A and further contributed to the development of insulin resistance... - Population-based study on the prevalence and correlates of orthostatic hypotension/hypertension and orthostatic dizzinessJin Shang Wu
Department of Family Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
Hypertens Res 31:897-904. 2008..The risk of OHT increased with age and with supine systolic blood pressure in adults aged > or = 40 years. OH and OHT cannot be determined solely from the presence of OD because of their dissociation... - Population-based study on the prevalence and risk factors of orthostatic hypotension in subjects with pre-diabetes and diabetesJin Shang Wu
Department of Family Medicine, College of Medicine, National Cheng Kung University, Taiwan, Republic of China
Diabetes Care 32:69-74. 2009.... - Altered cardiac autonomic function may precede insulin resistance in metabolic syndromeChih Jen Chang
Department of Family Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Am J Med 123:432-8. 2010..We explored the alteration of cardiac autonomic function and insulin resistance in predisease community dwellers with different numbers of metabolic abnormalities... - Short sleep duration associated with a higher prevalence of metabolic syndrome in an apparently healthy populationMan Chun Wu
Department of Family Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan, 70403, Taiwan, ROC
Prev Med 55:305-9. 2012..To examine the association between sleep duration and metabolic syndrome in an apparently healthy Chinese population... - Serum fetuin-A concentrations are elevated in subjects with impaired glucose tolerance and newly diagnosed type 2 diabetesHorng Yih Ou
Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Clin Endocrinol (Oxf) 75:450-5. 2011..The aim of this study is to investigate the relationship among serum fetuin-A concentrations, IFG, IGT and NDD in Chinese subjects without nonalcoholic fatty liver disease (NAFLD)... - The correlates of leisure time physical activity among an adults population from southern TaiwanYi Ju Chen
Graduate Institute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Taiwan, Republic of China
BMC Public Health 11:427. 2011..The goal of this study was thus to explore the determinants influencing adults' leisure time physical activity (LTPA) in a city in southern Taiwan... - Prevalence of hearing impairment in an adult population in Southern TaiwanCheng Yu Lin
Department of Otolaryngology, Tainan Municipal Hospital, Tainan, Taiwan
Int J Audiol 46:732-7. 2007..1%) than in western populations (11.5%), but differences in the definition of hearing impairment severity and variation in sex distribution among studies may account for this higher prevalence... - 4G/5G promoter polymorphism of plasminogen activator inhibitor-1, lipid profiles, and ischemic strokeChih Hung Chen
Department of Neurology, Family Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
J Lab Clin Med 142:100-5. 2003..001) levels. Our findings suggest that PAI-1 4G/5G promoter polymorphism alone is not associated with ischemic stroke. However, this polymorphism influences lipid levels, and the underlying mechanism must be determined... - Non-leisure time physical activity is an independent predictor of longevity for a Taiwanese elderly population: an eight-year follow-up studyYu Pei Lin
Department of Family Medicine, Kaohsiung Municipal Min Shen Hospital, Kaohsiung, Taiwan
BMC Public Health 11:428. 2011..The aim of this study is to determine the relationship between leisure time physical activity (LTPA) and non-leisure time physical activity (NLTPA) on mortality among the elderly in Taiwan... - The association of serum lipids with the histological pattern of rectosigmoid adenoma in Taiwanese adultsZih Jie Sun
Department of Family Medicine, National Cheng Kung University College of Medicine and Hospital, Dou Liou Branch, No 345, Douliou City, Yunlin County 640, Taiwan
BMC Gastroenterol 11:54. 2011..Colorectal cancer mostly arises from adenomatous polyps of left colon. The aim of our study was to examine the association of serum lipids with the histological pattern of rectosigmoid adenoma... - Efficacy and safety of very-low-calorie diet in Taiwanese: a multicenter randomized, controlled trialWen Yuan Lin
Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan
Nutrition 25:1129-36. 2009..Very-low-calorie diets (VLCDs) are an effective method for weight reduction in Caucasians. This study investigated the efficacy and safety of two different VLCDs (450 or 800kcal/d) in obese Taiwanese... - The relationship between impaired fasting glucose and self-reported sleep quality in a Chinese populationHao Chang Hung
Division of Endocrinology and Metabolism, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Clin Endocrinol (Oxf) 78:518-24. 2013..However, there is limited research on the association between prediabetes and sleep quality. The aim of this study is to investigate this relationship in a Chinese population... - The association between self-reported sleep quality and metabolic syndromeHao Chang Hung
Division of Endocrinology and Metabolism, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
PLoS ONE 8:e54304. 2013..Short and long sleep duration are associated with metabolic syndrome. However, there is limited research on the association between sleep quality and metabolic syndrome, and thus the aim of this study is to investigate this relationship... - The relationship between psychiatric symptoms and glycemic status in a Chinese populationChung Hung Tsai
Department of Family Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan, Taiwan, ROC
J Psychiatr Res 46:927-32. 2012.... - Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the -308 tumor necrosis factor-alpha promoter geneSheng Yow Ho
Department of Radiation Oncology, Sin Lau Christian Hospital, Tainan, Taiwan
Cancer Causes Control 15:657-63. 2004..We conducted a study to evaluate the association between this polymorphism and hepatocellular carcinoma (HCC)...