Marie Lin

Summary

Affiliation: Mackay Memorial Hospital
Country: Taiwan

Publications

  1. ncbi request reprint Compatibility testing without a centrifuge: the slide Polybrene method
    Marie Lin
    Immunohematology Reference Laboratory, Mackay Memorial Hospital, 92 Section 2, Chuong Shan North Road, Taipei, Taiwan
    Transfusion 44:410-3. 2004
  2. ncbi request reprint Mitochondrial DNA association study of type 2 diabetes with or without ischemic stroke in Taiwan
    Jun Hun Loo
    Mackay Memorial Hospital, NO, 45, Minsheng Rd, Danshui District, New Taipei City, Taiwan
    BMC Res Notes 7:223. 2014
  3. pmc Association of HLA class I with severe acute respiratory syndrome coronavirus infection
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    BMC Med Genet 4:9. 2003
  4. ncbi request reprint The origin of Minnan and Hakka, the so-called "Taiwanese", inferred by HLA study
    M Lin
    Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 57:192-9. 2001
  5. doi request reprint Genetic variation in the vascular endothelial growth factor gene is associated with biliary atresia
    Hung Chang Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei Medical University, Nursing and Management College, Taipei, Taiwan
    J Clin Gastroenterol 44:135-9. 2010
  6. doi request reprint Gender-specific association of the interleukin 18 gene with symptomatic gallstone disease
    Shou Chuan Shih
    Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 28:744-9. 2013
  7. doi request reprint Lack of association of the vascular endothelial growth factor gene polymorphisms with Kawasaki disease in Taiwanese children
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, 45, Min Sheng Rd, Tamshui 25115, Taipei, Taiwan
    J Clin Immunol 28:322-8. 2008
  8. doi request reprint The -590 C/T and 8375 A/G interleukin-4 polymorphisms are not associated with Kawasaki disease in Taiwanese children
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 69:52-7. 2008
  9. doi request reprint Genetic variability of interleukin4 gene in Taiwanese children with biliary atresia
    Hung Chang Lee
    Department of Pediatrics, Mackay Memorial Hospital, New Taipei City, Taiwan
    Cytokine 57:402-5. 2012
  10. ncbi request reprint A novel IGnT allele responsible for the adult i phenotype
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 46:1982-7. 2006

Collaborators

Detail Information

Publications70

  1. ncbi request reprint Compatibility testing without a centrifuge: the slide Polybrene method
    Marie Lin
    Immunohematology Reference Laboratory, Mackay Memorial Hospital, 92 Section 2, Chuong Shan North Road, Taipei, Taiwan
    Transfusion 44:410-3. 2004
    ..SP is particularly suitable for use in developing countries where, due to limited resources, centrifuges and biologic reagents may not be readily available...
  2. ncbi request reprint Mitochondrial DNA association study of type 2 diabetes with or without ischemic stroke in Taiwan
    Jun Hun Loo
    Mackay Memorial Hospital, NO, 45, Minsheng Rd, Danshui District, New Taipei City, Taiwan
    BMC Res Notes 7:223. 2014
    ..We questioned whether mtDNA polymorphism, mitochondrial functions, age and gender influenced the occurrence of T2D with or without ischemic stroke (IS)...
  3. pmc Association of HLA class I with severe acute respiratory syndrome coronavirus infection
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    BMC Med Genet 4:9. 2003
    ....
  4. ncbi request reprint The origin of Minnan and Hakka, the so-called "Taiwanese", inferred by HLA study
    M Lin
    Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 57:192-9. 2001
    ..These observations suggests that this haplotype is the most well-conserved ancient haplotype of the Yueh...
  5. doi request reprint Genetic variation in the vascular endothelial growth factor gene is associated with biliary atresia
    Hung Chang Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei Medical University, Nursing and Management College, Taipei, Taiwan
    J Clin Gastroenterol 44:135-9. 2010
    ..We aimed to study the relationship between genetic variations of the VEGF gene and susceptibility to BA using both case-control and family-based methodologies...
  6. doi request reprint Gender-specific association of the interleukin 18 gene with symptomatic gallstone disease
    Shou Chuan Shih
    Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    J Gastroenterol Hepatol 28:744-9. 2013
    ..In this study, we investigated whether polymorphisms of the IL18 gene were associated with SGSD susceptibility...
  7. doi request reprint Lack of association of the vascular endothelial growth factor gene polymorphisms with Kawasaki disease in Taiwanese children
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, 45, Min Sheng Rd, Tamshui 25115, Taipei, Taiwan
    J Clin Immunol 28:322-8. 2008
    ..This study hypothesized that specific VEGF gene polymorphisms and their haplotypes are associated with KD susceptibility and CAL development in Taiwanese children...
  8. doi request reprint The -590 C/T and 8375 A/G interleukin-4 polymorphisms are not associated with Kawasaki disease in Taiwanese children
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 69:52-7. 2008
    ..These results suggest that IL-4 -590 C/T and 8375 A/G SNPs do not confer a relevant role in the susceptibility or CAL development of KD in Taiwanese children...
  9. doi request reprint Genetic variability of interleukin4 gene in Taiwanese children with biliary atresia
    Hung Chang Lee
    Department of Pediatrics, Mackay Memorial Hospital, New Taipei City, Taiwan
    Cytokine 57:402-5. 2012
    ..These results suggest that the tested polymorphisms of IL4 gene are unlikely to contribute significantly to BA susceptibility in Taiwanese children...
  10. ncbi request reprint A novel IGnT allele responsible for the adult i phenotype
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 46:1982-7. 2006
    ..This report describes molecular genetic analysis of a Taiwanese person with the adult i phenotype but without congenital cataracts...
  11. doi request reprint Genetic polymorphisms in the CD40 ligand gene and Kawasaki disease
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, 45, Min Sheng Rd, Tamshui, 25115 Taipei, Taiwan
    J Clin Immunol 28:405-10. 2008
    ....
  12. doi request reprint Association of an IL-4 gene haplotype with Graves disease in children: experimental study and meta-analysis
    Yann Jinn Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 72:256-61. 2011
    ..Our study showed an association between the IL-4 gene and GD in children, but only using a haplotype-based method, suggesting that this might be a better approach than evaluating individual SNPs...
  13. doi request reprint Association of interferon-gamma gene polymorphisms in Taiwanese children with biliary atresia
    Hung Chang Lee
    Departments of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    J Clin Immunol 30:68-73. 2010
    ..Interferon-gamma (IFN-gamma) is a key cytokine that affects immune-mediated inflammatory responses...
  14. ncbi request reprint Influence of HLA-DRB1 genes and the shared epitope on genetic susceptibility to rheumatoid arthritis in Taiwanese
    Shih Chia Liu
    Department of Orthopedic Surgery, Mackay Memorial Hospital, Taipei, Taiwan
    J Rheumatol 34:674-80. 2007
    ..To investigate the association of predisposing and protective HLA-DRB1 alleles with rheumatoid arthritis (RA) and its clinical markers in a Taiwanese population...
  15. ncbi request reprint Association of CT60 polymorphism of the CTLA4 gene with Graves' disease in Taiwanese children
    Suei Tsau Tsai
    Department of Pediatrics, Taiwan Adventist Hospital, Taipei, Taiwan
    J Pediatr Endocrinol Metab 21:665-72. 2008
    ..The CTLA4 gene is involved in the activity of T cells...
  16. doi request reprint Association of polymorphisms in the Interleukin-18 gene with susceptibility to biliary atresia
    Hung Chang Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    J Pediatr Gastroenterol Nutr 52:607-11. 2011
    ..In this study, we investigated whether polymorphisms of the IL18 gene were associated with susceptibility to BA...
  17. ncbi request reprint Anti-"Mi(a)" immunization is associated with HLA-DRB1*0901
    Chen Chung Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 49:472-8. 2009
    ..Anti-"Mi(a)" is one of the most important irregular red blood cell antibodies found in Taiwan. The aim of this study was to investigate whether specific HLA-DRB1 alleles are associated with anti-"Mi(a)" production...
  18. ncbi request reprint The molecular genetics of the human I locus and molecular background explain the partial association of the adult i phenotype with congenital cataracts
    Lung Chih Yu
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, and the Institute of Biochemical Sciences, College of Science, National Taiwan University, Taipei, Taiwan
    Blood 101:2081-8. 2003
    ..The results also suggest that the human blood group I gene should be reassigned to the IGnTC form, not the IGnTB form, as described previously...
  19. ncbi request reprint CTLA-4 gene and susceptibility to human papillomavirus-16-associated cervical squamous cell carcinoma in Taiwanese women
    Tsung Hsien Su
    Department of Gynecology and Obstetrics, Mackay Memorial Hospital, Tamshui, Taipei, Taiwan
    Carcinogenesis 28:1237-40. 2007
    ..Our results suggest that the -318 C/T variant in the promoter region of the CTLA-4 gene is associated with HPV-16-associated CSCC in Taiwanese women...
  20. pmc Genetic affinities between the Yami tribe people of Orchid Island and the Philippine Islanders of the Batanes archipelago
    Jun Hun Loo
    Transfusion Medicine and Molecular Anthropology Research Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    BMC Genet 12:21. 2011
    ..Then mitochondrial DNA polymorphism was also analyzed to determine the matrilineal relationships between Yami, Ivatan, and other East Asian populations...
  21. doi request reprint Investigation of cytotoxic T-lymphocyte-associated protein 4 gene polymorphisms in symptomatic gallstone disease
    Shou Chuan Shih
    Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 72:355-8. 2011
    ..No significant associations between symptomatic GSD and these 3 SNPs were observed. Our data suggest that CTLA4-318 C/T, +49 A/G, and CT60 A/G SNPs do not confer increased susceptibility to symptomatic GSD...
  22. pmc Traces of archaic mitochondrial lineages persist in Austronesian-speaking Formosan populations
    Jean A Trejaut
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    PLoS Biol 3:e247. 2005
    ....
  23. doi request reprint Primary autoimmune neutropenia in children in Taiwan
    Lin Yen Wang
    Pediatric Hematology Oncology, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    Transfusion 49:1003-6. 2009
    ..This study reviewed our experience with autoimmune neutropenia in children and investigated possible associations with HLA-DR and HLA-DQ alleles...
  24. pmc Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles
    Pei Lung Chen
    Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan
    PLoS ONE 6:e16635. 2011
    ....
  25. ncbi request reprint A novel A allele with 664G>A mutation identified in a family with the Am phenotype
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 45:63-9. 2005
    ..The Am phenotype has been characterized as a weak expression of the A antigen on red blood cells but the presence of a normal quantity of the A antigen in saliva. This study describes a molecular genetic analysis of members of an Am family...
  26. pmc Taiwan Y-chromosomal DNA variation and its relationship with Island Southeast Asia
    Jean A Trejaut
    Mackay Memorial Hospital, Taipei, Molecular Anthropology Laboratory, 45 Min Sheng Road, 225115 Tamsui, New Taipei City, Taiwan
    BMC Genet 15:77. 2014
    ....
  27. pmc Ancient migration routes of Austronesian-speaking populations in oceanic Southeast Asia and Melanesia might mimic the spread of nasopharyngeal carcinoma
    Jean Trejaut
    Mackay Memorial Hospital, 45 Min Sheng Road, Tamsui 25115, Taiwan
    Chin J Cancer 30:96-105. 2011
    ..Outstanding findings were obtained on the routes of migration that occurred along with the spread of NPC during the settlement of insular Asia. The results of this analysis will be discussed using a conceptual approach...
  28. doi request reprint A novel HLA-DRB1 allele, DRB*090202, is identified in a Taiwanese family
    C C Chu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taiwan
    Tissue Antigens 74:262-3. 2009
    ..Human leukocyte antigen-DRB1*090202 has two synonymous nucleotide substitutions with DRB1*090201 at codons 57 and 58, which may be the result of a gene conversion...
  29. ncbi request reprint HLA-DQB1*0317 is a novel allele with an unusual DR-DQ haplotype
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 69:370-2. 2007
    ..HLA-DQB1*0317 may have arisen by gene conversion from the DQB1*030302 backbone, leading to one amino acid change from Leu to Gly at codon 26...
  30. doi request reprint Responses to booster hepatitis B vaccination are significantly correlated with genotypes of human leukocyte antigen (HLA)-DPB1 in neonatally vaccinated adolescents
    Tzu Wei Wu
    Department of Medicine, Mackay Medical College, No 46, Sec 3, Jhong Jheng Rd, San Jhih Dist, New Taipei City, 252, Taiwan
    Hum Genet 132:1131-9. 2013
    ..HLA-DBP1 may also determine the long-term persistence of response to HB vaccination. ..
  31. ncbi request reprint HLA-DRB1 alleles and cervical squamous cell carcinoma: experimental study and meta-analysis
    Yuh Cheng Yang
    Department of Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 67:331-40. 2006
    ..Larger studies may be needed, particularly in various ethnic groups, to further substantiate these associations...
  32. ncbi request reprint Diversity of HLA among Taiwan's indigenous tribes and the Ivatans in the Philippines
    C C Chu
    Transfusion Medicine Research Laboratory and Immunohematology Reference Laboratory, Mackay Memorial Hospital, 92, Sec. 2 Chung-Shan N. Road, Taipei, Taiwan
    Tissue Antigens 58:9-18. 2001
    ....
  33. ncbi request reprint Genetic variations of HLA-DRB1 and susceptibility to Kawasaki disease in Taiwanese children
    Fu Yuan Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 68:69-74. 2007
    ..If immunogenetic determinants are involved in this disease and its complications in Taiwanese children, they must involve genes other than HLA-DRB1...
  34. ncbi request reprint Taiwan experience suggests that RhD typing for blood transfusion is unnecessary in southeast Asian populations
    Marie Lin
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 46:95-8. 2006
    ..This report is the retrospective evaluation of the outcome of abolishing RhD typing for Taiwanese...
  35. doi request reprint Molecular genetics of the blood group I system and the regulation of I antigen expression during erythropoiesis and granulopoiesis
    Lung Chih Yu
    Institute of Biochemical Sciences, College of Life Science, National Taiwan University, Taipei, Taiwan
    Curr Opin Hematol 18:421-6. 2011
    ..The molecular genetics of the blood group I system and the regulation mechanism for I antigen expression in postnatal red blood cells are intriguing. This review summarizes their elucidation and recent findings...
  36. ncbi request reprint A novel HLA-DRB1 allele, DRB*1611, is identified in two Taiwanese individuals
    C C Chu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 74:175-6. 2009
    ..Human leukocyte antigen (HLA)-DRB1*1611 has one nucleotide change at codon 14 (GAG-->AAG) from DRB1*160201, resulting in a coding change from Glu to Lys...
  37. doi request reprint Identification of a novel HLA-B allele, B*460102, in three Taiwanese individuals
    C C Chu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 73:374-5. 2009
    ..We here report a new human leukocyte antigen (HLA)-B allele, B*460102, which differs from B*460101 by synonymous substitution at the third nucleotide of codon 74 (GAC-->GAT) and independently found in three Taiwanese individuals...
  38. ncbi request reprint Identification of two new HLA-DRB1 alleles: HLA-DRB1*1350 and DRB1*140502
    Z X Chen
    Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 64:300-3. 2004
    ..However, it causes no change in amino acid sequence and would therefore not have direct clinical implications...
  39. doi request reprint Molecular analysis of HLA-DRB1 allelic associations with systemic lupus erythematous and lupus nephritis in Taiwan
    C F Pan
    Departments of Nephrology, Mackay Memorial Hospital, Taipei Departments of Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    Lupus 18:698-704. 2009
    ..In Taiwanese people, the DRB1*0301 and DRB1*1501 alleles are significant risk factors for SLE, while the DRB1*1202 allele is protective for LN...
  40. ncbi request reprint Identification of a novel human leukocyte antigen-B allele, B*4048, in Taiwan
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 68:180-1. 2006
  41. doi request reprint Thomsen-Friedenreich activation in infants with necrotizing enterocolitis in Taiwan
    Lin Yen Wang
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 51:1972-6. 2011
    ..However, no data are available on the frequency of T activation in infants with NEC in Taiwan...
  42. ncbi request reprint Identification of two novel HLA-DRB1 alleles, DRB1*0903 and DRB1*1145
    C J Liu
    Oral and Maxillofacial Surgery, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 64:99-101. 2004
    ..Two complete exon 2 sequences of those new alleles had been deposited in the EMBL Sequence Database under accession number AY465114 and AY465115, respectively...
  43. ncbi request reprint Identification of two novel HLA-DRB1 alleles, HLA-DRB1*1214 and HLA-DRB1*1215, in two Taiwanese individuals
    H L Lee
    Transfusion Medicine and Molecular Anthropology Research Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Int J Immunogenet 35:423-6. 2008
    ....
  44. doi request reprint Identification of HLA-B*9521 in Taiwan
    C C Chu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taiwan
    Tissue Antigens 74:445-6. 2009
    ..We here report a new HLA-B allele, B*9521, which differs from B*1544 at codon 67 (TCC-->TGC)...
  45. ncbi request reprint Identification of a new HLA-DRB1 allele, HLA-DRB1*0436
    C C Chu
    Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 63:279-81. 2004
    ..These substitutions constitute a motif that is also seen in other DRB1*11 alleles. It is possible that the new allele resulted from a gene conversion event...
  46. ncbi request reprint A newly identified HLA-C allele: Cw*1210, and confirmation of HLA-Cw*080102
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 66:61-3. 2005
    ....
  47. ncbi request reprint A*1126: a novel HLA-A11 variant identified by sequence-based typing method
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 68:263-5. 2006
  48. ncbi request reprint A novel HLA-A2 variant, A*9203, identified by sequence-based typing
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Int J Immunogenet 34:13-5. 2007
    ..Since this substitution motif is also seen in A*11 and A*03, it is likely that a gene conversion event from A*11 or A*03 to a A*0207 backbone may have been the process used in generating HLA-A*9203...
  49. ncbi request reprint Molecular genetic analysis for the B(3) allele
    Lung Chih Yu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Tamshui, Taipei, Taiwan
    Blood 100:1490-2. 2002
    ..The B(3) transcript without exon 3 predicts a B-transferase product that lacks 19 amino acids in the N-terminal segment...
  50. ncbi request reprint The use of genotyping to predict the phenotypes of human platelet antigens 1 through 5 and of neutrophil antigens in Taiwan
    C C Chu
    Transfusion Medicine Research Laboratory and the Immunohematology Reference Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 41:1553-8. 2001
    ..In Taiwan, all of the HNA-1 null found was due to the deletion of the FCGR3B gene, and this deletion may be widely distributed in the Ami tribe...
  51. ncbi request reprint Polymorphism and distribution of the Secretor alpha(1,2)-fucosyltransferase gene in various Taiwanese populations
    L C Yu
    Transfusion Medicine Research Laboratory, the Immunohematology Reference Laboratory, and the Blood Bank, Mackay Memorial Hospital, Taipei, Taiwan
    Transfusion 41:1279-84. 2001
    ..The distribution of various Lewis phenotypes among the Taiwanese population groups has been shown to vary considerably...
  52. ncbi request reprint A novel HLA-B allele, B*5612, identified by sequence-based typing method
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taiwan
    Int J Immunogenet 33:343-5. 2006
    ..As this sequence motif was not found in the Asian population, it is likely that HLA-B*5612 is the product of a complex mechanism of implying a dual gene conversion event...
  53. doi request reprint Identification of HLA-B*5410 in Taiwan
    C C Chu
    Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 73:611-2. 2009
    ..A new human leukocyte antigen-B allele, B*5410, has been detected in Taiwan. It has one nucleotide change from B*5401 at codon 156 (CTG-->CGG), resulting in one amino acid change (L-->R)...
  54. ncbi request reprint Two novel HLA-DRB1 alleles identified using a sequence-based typing: HLA-DRB1*1443 and HLA-DRB1*1351*
    C C Chu
    Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 64:308-10. 2004
    ..Both new alleles present unique polymorphisms, which have not been seen among other DRB1 alleles and which have no known effect on peptide binding...
  55. ncbi request reprint Cytokine gene polymorphisms in Taiwan
    J A Trejaut
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 64:492-9. 2004
    ..Little differences were observed between the Minnan and the Hakka. On the other hand, the Minnan and Hakka showed significant differences with the indigenous people...
  56. ncbi request reprint A novel HLA-DRB1 allele, DRB1*0832, identified by sequence-based typing method
    C W Dang
    Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Tissue Antigens 70:527-9. 2007
    ..Human leukocyte antigen-DRB1*0832 may have arisen by gene conversion from a DRB1*080302 backbone, leading to amino acid changes at codons 26, 28, 30, 32, 37, and 38...
  57. ncbi request reprint Molecular basis of the Kell-null phenotype: a mutation at the splice site of human KEL gene abolishes the expression of Kell blood group antigens
    L C Yu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taipei 251, Taiwan
    J Biol Chem 276:10247-52. 2001
    ..The segment contains all of the known positions responsible for characterizing different Kell antigens, and this explains the lack of all Kell antigens in Ko red cells...
  58. ncbi request reprint Alloimmunization among patients with transfusion-dependent thalassemia in Taiwan
    L Y Wang
    Division of Pediatric Hematology Oncology, Mackay Memorial Hospital, Taipei, Taiwan
    Transfus Med 16:200-3. 2006
    ..Alloimmunization to erythrocyte antigens is a frequent complication in transfusion-dependent thalassemia...
  59. ncbi request reprint Molecular basis of the adult i phenotype and the gene responsible for the expression of the human blood group I antigen
    L C Yu
    Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Blood 98:3840-5. 2001
    ....
  60. ncbi request reprint Change in demographic picture and increase of drug resistance in pulmonarytuberculosis in a 10-year interval in Taiwan
    T C Y Tsao
    Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
    Infection 30:75-80. 2002
    ..This study was designed to compare the change in demographics, medical characteristics and drug resistance of patients with active pulmonary tuberculosis (TB) between two time periods within a 10-year interval...
  61. ncbi request reprint The molecular basis for the B(A) allele: an amino acid alteration in the human histoblood group B alpha-(1,3)-galactosyltransferase increases its intrinsic alpha-(1,3)-N-acetylgalactosaminyltransferase activity
    L C Yu
    Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    Biochem Biophys Res Commun 262:487-93. 1999
    ..This new B(A) allele shows that not only the four critical residues but also the neighboring areas may influence the specificity of the A and B transferases...
  62. doi request reprint Effects of financing smoking cessation outpatient services in Taiwan
    F C Chang
    Bureau of Health Promotion, Department of Health, Taiwan, 2, Chang ching Street, Shin juang City, Taipei, Taiwan
    Tob Control 17:183-9. 2008
    ..This study assesses the effects of a 2005 increase in funding for smoking cessation services on provider participation, patient utilisation of smoking cessation services and cessation outcome at a six-month follow-up...
  63. ncbi request reprint The incidence and significance of anti-"Mia" in Taiwan
    R E Broadberry
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan, Republic of China
    Transfusion 34:349-52. 1994
    ..CONCLUSION: It may be important to include the Mill phenotype in the antibody screening of sera from Chinese patients...
  64. doi request reprint Frequencies of the JKnull (IVS5-1g>a) allele in Taiwanese, Fujian, Filipino, and Indonesian populations
    Marie Lin
    Transfusion 48:1768. 2008
  65. ncbi request reprint Molecular genetic analysis for the Ae1 and A3 alleles
    Chien Feng Sun
    Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan County, Taiwan
    Transfusion 43:1138-44. 2003
    ..In addition to the common ABO phenotypes, numerous phenotypes with a weak expression of the A or B antigens on RBCs have been found. This study describes the molecular genetic analysis of the Ael and the A3 phenotypes...
  66. doi request reprint Climate change and postglacial human dispersals in southeast Asia
    Pedro Soares
    Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK
    Mol Biol Evol 25:1209-18. 2008
    ..This suggests that global warming and sea-level rises at the end of the Ice Age, 15,000-7,000 years ago, were the main forces shaping modern human diversity in the region...
  67. pmc HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
    Shuen Iu Hung
    Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan
    Proc Natl Acad Sci U S A 102:4134-9. 2005
    ..Our results indicated that allopurinol-SCAR is strongly associated with a genetic predisposition in Han Chinese. In particular, HLA-B*5801 allele is an important genetic risk factor for this life-threatening condition...
  68. ncbi request reprint Haplotype frequencies of nine Y-chromosome STR loci in the Taiwanese Han population
    Li Chin Tsai
    Department of Forensic Science, Central Police University, 56 Shu Jen Road, Kwei San, Taoyuan, 33334, Taiwan, ROC
    Int J Legal Med 116:179-83. 2002
    ..The haplotype diversity (99.99%) and discrimination capacity (88.5%) were calculated. A family study of 109 father/son pairs in 100 families showed 2 mutational events in the DYS389II locus and 1 in the DYS392 locus...
  69. ncbi request reprint Immunoglobulin allotypes among Taiwan aborigines: evidence of malarial selection could affect studies of population affinity
    Moses S Schanfield
    Department of Human Genetics University of Michigan, Ann Arbor, USA
    Hum Biol 74:363-79. 2002
    ....
  70. ncbi request reprint The CBLB gene and Graves' disease in children
    Chia Ching Chen
    Department of Pediatrics, Chiayi Christian Hospital, Chiayi, Taiwan
    J Pediatr Endocrinol Metab 18:1119-26. 2005
    ..This study demonstrates that the C/T polymorphism in exon 10 of the CBLB gene is not associated with Graves' disease in children...