Sheng Nan Wu

Summary

Affiliation: Kaohsiung Veterans General Hospital
Country: Taiwan

Publications

  1. request reprint
    Wu S, Chen H, Liu Y, Chiang H. Block of L-type Ca2+ current by beauvericin, a toxic cyclopeptide, in the NG108-15 neuronal cell line. Chem Res Toxicol. 2002;15:854-60 pubmed
    ..Under current-clamp configuration, beauvericin reduced the firing frequency of action potentials. Therefore, this study indicates that beauvericin is a relatively specific inhibitor of L-type Ca2+ current in NG108-15 cells. ..
  2. request reprint
    Wu S, Chen H, Lin Y. The mechanism of inhibitory actions of S-petasin, a sesquiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med. 2003;69:118-24 pubmed
    ..These results demonstrate that S-petasin can interact directly with L-type Ca2+ channels in NG108-15 cells. These effects could contribute to the regulation of neuronal activity if similar results were found in neurons in vivo. ..

Detail Information

Publications2

  1. request reprint
    Wu S, Chen H, Liu Y, Chiang H. Block of L-type Ca2+ current by beauvericin, a toxic cyclopeptide, in the NG108-15 neuronal cell line. Chem Res Toxicol. 2002;15:854-60 pubmed
    ..Under current-clamp configuration, beauvericin reduced the firing frequency of action potentials. Therefore, this study indicates that beauvericin is a relatively specific inhibitor of L-type Ca2+ current in NG108-15 cells. ..
  2. request reprint
    Wu S, Chen H, Lin Y. The mechanism of inhibitory actions of S-petasin, a sesquiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med. 2003;69:118-24 pubmed
    ..These results demonstrate that S-petasin can interact directly with L-type Ca2+ channels in NG108-15 cells. These effects could contribute to the regulation of neuronal activity if similar results were found in neurons in vivo. ..