Shang Jyh Hwang

Summary

Affiliation: Kaohsiung Medical University
Country: Taiwan

Publications

  1. pmc CYP17A1 intron mutation causing cryptic splicing in 17α-hydroxylase deficiency
    Daw Yang Hwang
    Division of Nephrology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 6:e25492. 2011
  2. doi request reprint Impact of the clinical conditions at dialysis initiation on mortality in incident haemodialysis patients: a national cohort study in Taiwan
    Shang Jyh Hwang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 25:2616-24. 2010
  3. ncbi request reprint Endothelin-1 regulates parathyroid hormone expression of human parathyroid cells
    J M Chang
    Department of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Chung Ho Memorial Hospital, Taiwan
    Clin Nephrol 66:25-31. 2006
  4. doi request reprint Association of hyperuricemia with renal outcomes, cardiovascular disease, and mortality
    Wan Chun Liu
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Taiwan
    Clin J Am Soc Nephrol 7:541-8. 2012
  5. pmc Association of interleg BP difference with overall and cardiovascular mortality in hemodialysis
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 7:1646-53. 2012
  6. pmc Association of cholesterol levels with mortality and cardiovascular events among patients with CKD and different amounts of proteinuria
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Faculties of Medicine and, Renal Care, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 8:1915-26. 2013
  7. doi request reprint Significant correlation between ratio of brachial pre-ejection period to ejection time and left ventricular ejection fraction and mass index in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 26:1895-902. 2011
  8. doi request reprint Ratio of transmitral E-wave velocity to early diastole mitral annulus velocity with cardiovascular and renal outcomes in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC
    Nephron Clin Pract 123:52-60. 2013
  9. pmc Association of dyslipidemia with renal outcomes in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e55643. 2013
  10. pmc Echocardiographic parameters are independently associated with rate of renal function decline and progression to dialysis in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Tzyou First Road, Kaohsiung 807, Taiwan
    Clin J Am Soc Nephrol 6:2750-8. 2011

Collaborators

Detail Information

Publications80

  1. pmc CYP17A1 intron mutation causing cryptic splicing in 17α-hydroxylase deficiency
    Daw Yang Hwang
    Division of Nephrology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 6:e25492. 2011
    ..The IVS1 +2T>C mutation abolished most 17α-hydroxylase/17, 20-lyase enzyme activity by aberrant mRNA splicing to an intronic pseudo-exon, causing a frame shift and early termination...
  2. doi request reprint Impact of the clinical conditions at dialysis initiation on mortality in incident haemodialysis patients: a national cohort study in Taiwan
    Shang Jyh Hwang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 25:2616-24. 2010
    ..We studied factors potentially related to the mortality in incident haemodialysis (HD) patients...
  3. ncbi request reprint Endothelin-1 regulates parathyroid hormone expression of human parathyroid cells
    J M Chang
    Department of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Chung Ho Memorial Hospital, Taiwan
    Clin Nephrol 66:25-31. 2006
    ..We propose that ET-1 may regulate the pathogenesis of uremic hyperparathyroidism. However, this was not directly demonstrated in human parathyroid glands...
  4. doi request reprint Association of hyperuricemia with renal outcomes, cardiovascular disease, and mortality
    Wan Chun Liu
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Taiwan
    Clin J Am Soc Nephrol 7:541-8. 2012
    ..Hyperuricemia is an independent risk factor for mortality, cardiovascular disease, and renal disease in general population. However, the relationship between hyperuricemia with clinical outcomes in CKD remains controversial...
  5. pmc Association of interleg BP difference with overall and cardiovascular mortality in hemodialysis
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 7:1646-53. 2012
    ..This study investigated whether an interleg BP difference was associated with peripheral vascular disease and overall and cardiovascular mortality in hemodialysis patients...
  6. pmc Association of cholesterol levels with mortality and cardiovascular events among patients with CKD and different amounts of proteinuria
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Faculties of Medicine and, Renal Care, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 8:1915-26. 2013
    ..However, it is unclear whether the relationship of total cholesterol with cardiovascular events and mortality varies by proteinuria...
  7. doi request reprint Significant correlation between ratio of brachial pre-ejection period to ejection time and left ventricular ejection fraction and mass index in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 26:1895-902. 2011
    ..The aims of this study were to assess whether bPEP/bET is a useful parameter in evaluation of LVMI and LVEF in patients with CKD and to evaluate the diagnostic value of bPEP/bET in the prediction of LVEF < 50%...
  8. doi request reprint Ratio of transmitral E-wave velocity to early diastole mitral annulus velocity with cardiovascular and renal outcomes in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC
    Nephron Clin Pract 123:52-60. 2013
    ..This study is designed to assess whether the ratio of transmitral E-wave velocity (E) to early diastole mitral velocity (Ea) is associated with cardiovascular events and progression to dialysis in patients with CKD stages 3-5...
  9. pmc Association of dyslipidemia with renal outcomes in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e55643. 2013
    ..Our study demonstrated that certain levels of dyslipidemia were independently associated with RRT and rapid renal progression in CKD stage 3-5. Assessment of lipid profile may help identify high risk groups with adverse renal outcomes...
  10. pmc Echocardiographic parameters are independently associated with rate of renal function decline and progression to dialysis in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Tzyou First Road, Kaohsiung 807, Taiwan
    Clin J Am Soc Nephrol 6:2750-8. 2011
    ..This study is designed to assess whether echocardiographic parameters are associated with rate of renal function decline and progression to dialysis in CKD stage 3 to 5 patients...
  11. pmc Brachial-ankle pulse wave velocity and rate of renal function decline and mortality in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 6:724-32. 2011
    ..The aim of this study was to investigate whether there was an independent association between brachial-ankle pulse wave velocity (baPWV), a marker of arterial stiffness, and renal function progression in CKD patients...
  12. doi request reprint A new systolic parameter defined as the ratio of brachial pre-ejection period to brachial ejection time predicts overall and cardiovascular mortality in hemodialysis patients
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Hypertens Res 33:492-8. 2010
    ..Screening hemodialysis patients by means of bPEP/bET may help to identify a high-risk group for increased mortality...
  13. ncbi request reprint Hepatitis C viremia increases the association with type 2 diabetes mellitus in a hepatitis B and C endemic area: an epidemiological link with virological implication
    Jee Fu Huang
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, and Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Gastroenterol 102:1237-43. 2007
    ..This study aimed to elucidate the link between T2DM and viral hepatitis infections, especially HCV infection. It also aimed to analyze the associated virological characteristics and implication...
  14. pmc Predicting mortality of incident dialysis patients in Taiwan--a longitudinal population-based study
    Ping Hsun Wu
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 8:e61930. 2013
    ..The aim of this study is to perform a population-based cohort study to investigate the survival rate by age and Charlson comorbidity index (CCI) in incident dialysis patients...
  15. pmc Association of hsCRP, white blood cell count and ferritin with renal outcome in chronic kidney disease patients
    Yi Chun Tsai
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 7:e52775. 2012
    ..Instead, WBC count was not associated with renal outcome. In conclusion, elevated levels of hsCRP and ferritin are risk factors associated with RRT and rapid renal progression in advanced CKD patients...
  16. doi request reprint Ankle brachial index as a predictor for mortality in patients with chronic kidney disease and undergoing haemodialysis
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Nephrology (Carlton) 15:294-9. 2010
    ..The aim of this study was to investigate the predictors for mortality by using ABI value in patients with CKD and undergoing haemodialysis in Taiwan...
  17. ncbi request reprint Association of fluid overload with kidney disease progression in advanced CKD: a prospective cohort study
    Yi Chun Tsai
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Am J Kidney Dis 63:68-75. 2014
    ..Accordingly, the aim of the study was to assess the association of the severity of fluid status and kidney disease progression in an advanced CKD cohort...
  18. doi request reprint Performance of the Framingham risk score in patients receiving hemodialysis
    Jiun Chi Huang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrology (Carlton) 18:510-5. 2013
    ..Our objectives are to determine whether FRS is associated with overall and cardiovascular mortality and the role of new risk markers when they were added to a FRS model in hemodialysis patients...
  19. pmc Left atrial diameter and albumin with renal outcomes in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 812 Kaohsiung, Taiwan
    Int J Med Sci 10:575-84. 2013
    ..We examined the association between albumin and indexed LAD (indexed to height) and assessed whether the combination of indexed LAD and albumin was independently associated with renal outcomes in patients with CKD stages 3-5...
  20. pmc Framingham risk score with cardiovascular events in chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e60008. 2013
    ..Future study is needed to assess whether risk assessment enhanced by using these biomarkers and echocardiographic parameters might contribute to more effective prediction and better care for patients...
  21. doi request reprint Association of symptoms of depression with progression of CKD
    Yi Chun Tsai
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan
    Am J Kidney Dis 60:54-61. 2012
    ..This study investigates the association of depressive symptoms with clinical outcomes in patients with CKD not requiring dialysis...
  22. doi request reprint Echocardiographic parameters are independently associated with increased cardiovascular events in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 27:1064-70. 2012
    ..The aim of this study is to assess whether echocardiographic parameters are independently associated with increased CV events in patients with CKD Stages 3-5...
  23. doi request reprint Slowing renal function decline in chronic kidney disease patients after nephrology referral
    Szu Chia Chen
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrology (Carlton) 13:730-6. 2008
    ..We aimed to study the decline in renal function and factors related to the change in renal function before and after referral...
  24. pmc Hypokalemia, its contributing factors and renal outcomes in patients with chronic kidney disease
    Hsiao Han Wang
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e67140. 2013
    ..In the chronic kidney disease (CKD) population, the impact of serum potassium (sK) on renal outcomes has been controversial. Moreover, the reasons for the potential prognostic value of hypokalemia have not been elucidated...
  25. doi request reprint Increasing prevalence of peripheral artery occlusive disease in hemodialysis patients: a 2-year follow-up
    Szu Chia Chen
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Med Sci 343:440-5. 2012
    ..9 is a reliable marker for PAOD. The aims of the 2-year longitudinal study were to assess whether there was a progression in PAOD and to find out the determinants of ABI progression in hemodialysis patients...
  26. doi request reprint Impact of late-stage CKD and aging on medical utilization in the elderly population: a closed-cohort study in Taiwan
    Ming Yen Lin
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Nephrol Dial Transplant 25:3230-5. 2010
    ..However, population-based research on how the elderly with CKD utilize medical services is still unexplored. We aimed to examine the effects of CKD severity and aging on medical utilizations in the elderly population...
  27. doi request reprint Increased risk of mortality in the elderly population with late-stage chronic kidney disease: a cohort study in Taiwan
    Shang Jyh Hwang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 23:3192-8. 2008
    ..However, the transition from chronic kidney disease (CKD) to death or ESRD remains unclear. This study aimed to investigate the impact of late-stage CKD on all-cause and cause-specific mortality by identifying the CKD population...
  28. ncbi request reprint A systolic parameter defined as the ratio of brachial pre-ejection period to brachial ejection time predicts cardiovascular events in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC
    Circ J 74:2206-10. 2010
    ..Brachial PEP (bPEP) and brachial ET (bET) can be automatically determined from an ankle-brachial index (ABI)-form device. The aim of this study is to investigate whether bPEP/bET is a useful predictor for CV events in patients with CKD...
  29. pmc The rs1014290 polymorphism of the SLC2A9 gene is associated with type 2 diabetes mellitus in Han Chinese
    Wan Chun Liu
    Department of Internal Medicine, Kaohsiung Municipal Hsiaokang Hospital, Kaohsiung, Taiwan
    Exp Diabetes Res 2011:527520. 2011
    ..UA was identified as a risk factor for type 2 diabetes mellitus (DM). We investigated whether the SLC2A9 gene variations are associated with type 2 DM in Han Chinese...
  30. ncbi request reprint 1-alpha,25-Dihydroxyvitamin D3 regulates inducible nitric oxide synthase messenger RNA expression and nitric oxide release in macrophage-like RAW 264.7 cells
    Jer Ming Chang
    Department of Nephrology, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Lab Clin Med 143:14-22. 2004
    ..In the case of tuberculosis infection, increased 1,25(OH)(2)D(3) synthesis may further contribute to the development of an unwanted phenomenon-hypercalcemia...
  31. ncbi request reprint Correlation of plasma homocysteine level with arterial stiffness and pulse pressure in hemodialysis patients
    Jer Chia Tsai
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, 100 Shih Chuan First Road, Kaohsiung, 807, Taiwan
    Atherosclerosis 182:121-7. 2005
    ..005, P=0.005, respectively) independent of other classic risk factors for atherosclerosis. In conclusion, plasma homocysteine, along with serum ferritin, may act as an important predictor for arterial stiffness and PP in HD patients...
  32. doi request reprint Prevalence and risk factors for CKD in spouses and relatives of hemodialysis patients
    Jer Chia Tsai
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Kidney Dis 55:856-66. 2010
    ..A higher prevalence of chronic kidney disease (CKD) has been found in genetic relatives of patients with end-stage renal disease. However, the risk of CKD in nongenetic spouses of patients with end-stage renal disease is still unknown...
  33. pmc Association of metabolic syndrome and albuminuria with cardiovascular risk in occupational drivers
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan
    Int J Mol Sci 14:21997-2010. 2013
    ..We investigated the prevalence of MetS, albuminuria and cardiovascular risk, and its associated risk factors in occupational drivers;..
  34. pmc Discrepancy between serological and virological analysis of viral hepatitis in hemodialysis patients
    Jer Ming Chang
    1 Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung, Taiwan 2 Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan 5 Renal Care, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Int J Med Sci 11:436-41. 2014
    ..Some patients categorized to have viral hepatitis were found to be non-viremic. To clarify the discrepancy between the serological tests in HD patients, we conducted the study...
  35. pmc Factors associated with CKD in the elderly and nonelderly population
    Ming Yen Lin
    Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 8:33-40. 2013
    ..The risk factors for CKD in different age groups remain unknown. This community-based study aimed to identify the risk factors for CKD in elderly and nonelderly patients...
  36. ncbi request reprint Difficulty in diagnosis and treatment of dengue hemorrhagic fever in patients with chronic renal failure: report of three cases of mortality
    Mei Chuan Kuo
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Trop Med Hyg 76:752-6. 2007
    ..However, to decrease mortality, the physician must pay great attention to ensure an early awareness of DHF/DSS and deliver a prompt and aggressive treatment of patients of dengue viral infections with chronic renal failure...
  37. pmc Stepwise increases in left ventricular mass index and decreases in left ventricular ejection fraction correspond with the stages of chronic kidney disease in diabetes patients
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Exp Diabetes Res 2012:789325. 2012
    ..This study was designed to assess the determinants of left ventricular mass index (LVMI) and left ventricular ejection fraction (LVEF) in diabetic patients at various stages of chronic kidney disease (CKD)...
  38. doi request reprint Chronic kidney disease care program improves quality of pre-end-stage renal disease care and reduces medical costs
    Shu Yi Wei
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Municipal United Hospital, Kaohsiung, Taiwan
    Nephrology (Carlton) 15:108-15. 2010
    ..Multidisciplinary care of patients with chronic kidney disease (CKD) provides better care outcomes. This study is to evaluate the effectiveness of a CKD care program on pre-end-stage renal disease (ESRD) care...
  39. pmc Significant correlation between ankle-brachial index and vascular access failure in hemodialysis patients
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Clin J Am Soc Nephrol 4:128-34. 2009
    ..The ankle-brachial index (ABI) is a reliable marker for atherosclerosis. The aim of this study was to evaluate the relationship between ABI <0.9 and VAF...
  40. doi request reprint Quality of life predicts risks of end-stage renal disease and mortality in patients with chronic kidney disease
    Yi Chun Tsai
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University
    Nephrol Dial Transplant 25:1621-6. 2010
    ..However, the prognostic role of QOL for survival in CKD remains unclear. We studied the relationship between QOL and risks of ESRD and mortality in CKD patients...
  41. ncbi request reprint P wave dispersion and maximum p wave duration are associated with renal outcomes in chronic kidney disease
    Jiun Chi Huang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 9:e101962. 2014
    ..Screening CKD patients on the basis of P wave dispersion and maximum P wave duration may help identify patients at high risk for worse renal outcomes. ..
  42. pmc Is fluid overload more important than diabetes in renal progression in late chronic kidney disease?
    Yi Chun Tsai
    Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 8:e82566. 2013
    ..In conclusion, fluid overload has a higher predictive value of an elevated risk for renal progression than diabetes in late CKD. ..
  43. ncbi request reprint HCV infection complicated with nephrotic syndrome, immune complex crescentic glomerulonephritis and acute renal failure: a case report
    Yi Chun Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Chun Ho Memorial Hospital, Taiwan
    Kaohsiung J Med Sci 21:470-4. 2005
    ..The attending clinicians faced what is a common dilemma, where an HCV-associated autoimmune disease inevitably switches to a lupus-like GN. Hence, we also discuss treatment...
  44. pmc High cost and low survival rate in high comorbidity incident elderly hemodialysis patients
    Yi Ting Lin
    Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Department of Public Health, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 8:e75318. 2013
    ..The aim of this study was to evaluate the long-term mortality of incident elderly dialysis patients using the Deyo-Charlson comorbidity index (CCI) and to assess the inpatient and outpatient visits along with non-dialysis costs...
  45. doi request reprint B7-1 expression regulates the hypoxia-driven cytoskeleton rearrangement in glomerular podocytes
    Jer Ming Chang
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kango Hospital, Kaohsiung, Taiwan
    Am J Physiol Renal Physiol 304:F127-36. 2013
    ..These hypoxia-induced changes were prevented in B7-knockdown podocytes, and they highlighted the importance of B7-1 expression in the hypoxia-related podocyte injuries...
  46. doi request reprint Inadequate energy and excess protein intakes may be associated with worsening renal function in chronic kidney disease
    Meng Chuan Huang
    Department of Nutrition, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    J Ren Nutr 18:187-94. 2008
    ..Dietary energy and protein play important roles in chronic kidney disease (CKD). This study investigates the relationship between energy/protein intake status and renal function in CKD...
  47. doi request reprint Planned creation of vascular access saves medical expenses for incident dialysis patients
    Ling Chu Wu
    Department of Nursing, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 25:521-9. 2009
    ....
  48. pmc Hepatitis C virus infection increases risk of developing end-stage renal disease using competing risk analysis
    Jia Jung Lee
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Faculty of Renal Care, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 9:e100790. 2014
    ..The association of HCV and risk of developing end-stage renal disease (ESRD) has not been analyzed with competing risk model...
  49. pmc Association of relatives of hemodialysis patients with metabolic syndrome, albuminuria and framingham risk score
    Jiun Chi Huang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    PLoS ONE 9:e96362. 2014
    ..We investigated the association of relatives of hemodialysis (HD) patients with MetS, albuminuria, and the FRS...
  50. doi request reprint High hepatitis B virus surface antigen levels and favorable interleukin 28B genotype predict spontaneous hepatitis C virus clearance in uremic patients
    Ming Lung Yu
    Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan Faculty of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Hepatol 60:253-9. 2014
    ..Host and viral factors interplay in the spontaneous clearance of hepatitis C virus (HCV) infection. We aimed to explore the roles of IL28B genotypes and hepatitis B virus (HBV) infections in spontaneous HCV seroclearance...
  51. ncbi request reprint Allopurinol-induced severe hypersensitivity with acute renal failure
    I Hung Chen
    Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 21:228-32. 2005
    ..AHS should be considered in the differential diagnosis of acute renal and hepatic failure in patients with evidence of allergy and recent use of allopurinol...
  52. pmc Chronic kidney disease itself is a causal risk factor for stroke beyond traditional cardiovascular risk factors: a nationwide cohort study in Taiwan
    Yi Chun Chen
    Division of Nephrology, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
    PLoS ONE 7:e36332. 2012
    ..In Taiwan, CVD is dominated by strokes but there is no robust evidence for a causal relationship between CKD and stroke. This study aimed to explore such causal association...
  53. doi request reprint Epidemiology, impact and preventive care of chronic kidney disease in Taiwan
    Shang Jyh Hwang
    Department of Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, College of Medicine, Kaohsiung, Taiwan
    Nephrology (Carlton) 15:3-9. 2010
    ..Provision of a more comprehensive public health strategy and better care plan for CKD should be achieved by future international collaborative efforts and research...
  54. doi request reprint Incidence, prevalence and mortality trends of dialysis end-stage renal disease in Taiwan from 1990 to 2001: the impact of national health insurance
    Wu Chang Yang
    Division of Nephrology, Department of Medicine, Taipei Veteran General Hospital, School of Medicine, National Yang Ming University Taipei 11217, Taiwan
    Nephrol Dial Transplant 23:3977-82. 2008
    ..Our aim was to explore the impact of NHI on the status and trends of ESRD epidemiology in Taiwan...
  55. pmc Modification of Diet in Renal Disease (MDRD) Study and CKD Epidemiology Collaboration (CKD-EPI) Equations for Taiwanese Adults
    Ling I Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 9:e99645. 2014
    ....
  56. pmc Dyslipoproteinemia and impairment of renal function in diabetic kidney disease: an analysis of animal studies, observational studies, and clinical trials
    Chi Chih Hung
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan
    Rev Diabet Stud 10:110-20. 2013
    ..We show that special subgroups could benefit from the statin treatment. ..
  57. ncbi request reprint Association of death from renal failure with calcium levels in drinking water
    Shang Jyh Hwang
    Department of Nephrology, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Toxicol Environ Health A 66:2327-35. 2003
    ..1 and 43.0 mg/L and 1.34 (1.12-1.60) for the group with calcium levels of 43.3 mg/L or more. There was a significant trend for increased risk of death from RF with higher calcium levels in drinking water...
  58. doi request reprint Chronic kidney disease prevention--a challenge for Asian countries: report of the Third Asian Forum of Chronic Kidney Disease Initiatives
    Jer Ming Chang
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung, Taiwan
    Clin Exp Nephrol 16:187-94. 2012
    ..In Theme 4, the care plan, strategies, and outcomes of timely initiation of dialysis in different countries were discussed. The final session started with a concise summary of all speeches and ended with a position statement...
  59. ncbi request reprint Vitamin D-mediated hypercalcemia as the initial manifestation of pulmonary cryptococcosis in an HIV-uninfected patient
    Jiun Chi Huang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan
    Intern Med 51:1793-6. 2012
    ..In summary, although HIV infection is a major risk factor for cryptococcosis, vitamin D-mediated hypercalcemia could be the initial presentation of pulmonary cryptococcosis in HIV-negative patients...
  60. doi request reprint False elevation of blood glucose levels measured by GDH-PQQ-based glucometers occurs during all daily dwells in peritoneal dialysis patients using icodextrin
    Chiu Yeh Tsai
    Department of Nursing, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Perit Dial Int 30:329-35. 2010
    ..We aimed to study blood glucose levels measured simultaneously using different methods in PD patients with switching of icodextrin, and throughout daily exchanges either using icodextrin or not...
  61. doi request reprint Association of hepatitis C and B virus infection with CKD in an endemic area in Taiwan: a cross-sectional study
    Jia Jung Lee
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Kidney Dis 56:23-31. 2010
    ..Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections may lead to nephropathy. However, the association between different types of viral hepatitis and chronic kidney disease (CKD) is not well established...
  62. doi request reprint Effects of a self-management program on patients with early-stage chronic kidney disease: a pilot study
    Chiu Chu Lin
    Kaohsiung Medical University, Chung Hwa University of Medical Technology, Fooyin University, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Appl Nurs Res 26:151-6. 2013
    ..Without intervention, renal function deteriorates in patients with chronic kidney disease (CKD)...
  63. pmc Impact of renal failure on the outcome of dengue viral infection
    Mei Chuan Kuo
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan
    Clin J Am Soc Nephrol 3:1350-6. 2008
    ..Physicians faced difficulty in diagnosis and treatment of these patients; however, the impacts of RF on the clinical presentations and outcomes of dengue infection have not been reported previously...
  64. ncbi request reprint Chylous ascites and chylothorax due to the existence of transdiaphragmatic shunting in an adult with nephrotic syndrome
    Yi Chun Chen
    Division of Nephrology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan
    Nephrol Dial Transplant 20:1501-2. 2005
  65. doi request reprint Comparison of ankle-brachial index and brachial-ankle pulse wave velocity between patients with chronic kidney disease and hemodialysis
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, KMU, Kaohsiung, Taiwan, ROC
    Am J Nephrol 29:374-80. 2009
    ....
  66. pmc Molecular and epidemiologic analysis of a county-wide outbreak caused by Salmonella enterica subsp. enterica serovar Enteritidis traced to a bakery
    Po Liang Lu
    Department of Internal Medicine, Kaohsiung Medical University Hospital, 100 Tzyou 1st Rd, Kaohsiung, Taiwan
    BMC Infect Dis 4:48. 2004
    ..Molecular and epidemiological surveys were performed to trace the possible source of infection...
  67. pmc Association between insulin resistance and development of microalbuminuria in type 2 diabetes: a prospective cohort study
    Chih Cheng Hsu
    Division of Health Policy Research and Development, Institute of Population Health Sciences, National Health Research Institutes, Taiwan
    Diabetes Care 34:982-7. 2011
    ..An association between insulin resistance and microalbuminuria in type 2 diabetes has often been found in cross-sectional studies. We aimed to reassess this relationship in a prospective Taiwanese cohort of type 2 diabetic subjects...
  68. ncbi request reprint Plasma and urinary endothelin-1 in focal segmental glomerulosclerosis
    H C Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Clin Lab Anal 15:59-63. 2001
    ..The same changes in plasma and urinary ET-1 levels were not observed in control rats injected with normal saline at the same frequency. Our results suggest that ET-1 may be involved in the pathogenesis of FSGS in both humans and rats...
  69. ncbi request reprint Combined herpes viral and candidal esophagitis in a CAPD patient: case report and review of literature
    Ling I Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Med Sci 333:191-3. 2007
    ..This is the first report of a dual infectious esophagitis in a uremic patient. Since infectious esophagitis may cause severe complications, early diagnosis and aggressive treatment are important...
  70. doi request reprint Reappraisal of the characteristics of glucose abnormalities in patients with chronic hepatitis C infection
    Jee Fu Huang
    Department of Internal Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Gastroenterol 103:1933-40. 2008
    ..It also aimed to investigate the related clinical, virological, and histological features of glucose abnormalities in HCV infection...
  71. ncbi request reprint Nail-patella syndrome with renal involvement and antecubital pterygia
    Jia Jung Lee
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Formos Med Assoc 101:655-60. 2002
    ..Both daughters also had the characteristic features of NPS. During follow-up 30 months after the initial examination, the patient had stable renal function and mild proteinuria...
  72. ncbi request reprint Changes of renal cortical Na-K ATPase activity, protein, and mRNA expression in ureteral obstruction
    Shang Jyh Hwang
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, No 100, Shih Chuan 1st Rd, Kaohsiung 807, Taiwan
    Kaohsiung J Med Sci 18:273-80. 2002
    ....
  73. doi request reprint Pharmacological dose of vitamin B12 is as effective as low-dose folinic acid in correcting hyperhomocysteinemia of hemodialysis patients
    Yi Wen Chiu
    Division of Nephrology, Departments of Internal Medicine and Renal Care, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Ren Fail 31:278-83. 2009
    ..9% respectively. Our study showed that IV pharmacologic dose of Vit B12 alone is as effective as low-dose folic acid in correcting hyperhomocysteinemia in chronic HD patients, and combining both drugs in low doses may have added effects...
  74. doi request reprint Pneumothorax in a female with renal angiomyolipoma
    Ping Hsun Wu
    Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan
    Kaohsiung J Med Sci 27:469-72. 2011
    ..Because of the nonspecific symptoms and high rate of complications, we should consider the possibility of LAM in patients diagnosed with AML. The association between renal AML and pulmonary LAM is reviewed...
  75. pmc The chronic kidney disease self-efficacy (CKD-SE) instrument: development and psychometric evaluation
    Chiu Chu Lin
    College of Nursing, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 27:3828-34. 2012
    ..A valid and reliable instrument for measuring CKD patients' self-efficacy is needed. This study aims to develop and test a new instrument to measure the DSE of patients with early stage CKD...
  76. doi request reprint Acute renal failure and its risk factors in Stevens-Johnson syndrome and toxic epidermal necrolysis
    Chi Chih Hung
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC
    Am J Nephrol 29:633-8. 2009
    ....
  77. doi request reprint Adherence to a diabetic care plan provides better glycemic control in ambulatory patients with type 2 diabetes
    Yi Wen Chiu
    Department of Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 25:184-92. 2009
    ..05). Diabetes care, with reinforcement from certified diabetes educators, significantly improved and maintained the effects on glycemic control in ambulatory patients with type 2 diabetes...
  78. doi request reprint Prescriptions for angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and monitoring of serum creatinine and potassium in patients with chronic kidney disease
    Pei Tzu Wang
    Department of Pharmacy, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 28:477-83. 2012
    ..In conclusion, prescription of ACEIs/ARBs was common in all stages of CKD. Most patients underwent Scr monitoring, but potassium monitoring was less frequent, and this should be improved in clinical practice...
  79. doi request reprint A comparative assessment of survival between propensity score-matched patients with peritoneal dialysis and hemodialysis in Taiwan
    Yu Kang Chang
    Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan
    Medicine (Baltimore) 91:144-51. 2012
    ..Studies in which patients who are appropriate for either modality are randomly assigned to HD or PD may provide helpful information to clinicians and patients...
  80. ncbi request reprint Hepatitis C viral genotype influences the clinical outcome of patients with acute posttransfusion hepatitis C
    S J Hwang
    Department of Family Medicine, Veterans General Hospital-Taipei, National Yang-Ming University School of Medicine, 201 Shih-Pai Road, Section 2, Taipei, 11217, Taiwan, Republic of China
    J Med Virol 65:505-9. 2001
    ..Therefore, the HCV genotype can influence the outcome of patients with acute HCV infection...