Tsung Hsien Chang


Affiliation: Kaohsiung Veterans General Hospital
Country: Taiwan


  1. Chen B, Chang J, Huang T, Chen J, Chen Y, Jan M, et al. Parechovirus A Detection by a Comprehensive Approach in a Clinical Laboratory. Viruses. 2018;10: pubmed publisher
    ..In conclusion, this study established a protocol for enterovirus and HPeV virus identification that combines conventional and molecular methods and would be beneficial for HPeV diagnosis. ..
  2. Wei C, Wang S, Ye J, Hwang T, Cheng M, Sung P, et al. New Anti-Inflammatory Aporphine and Lignan Derivatives from the Root Wood of Hernandia nymphaeifolia. Molecules. 2018;23: pubmed publisher
    ..40 μg/ml. ..
  3. Chang T, Chen S, Yu C, Lin Y, Chen Y, Kubota T, et al. Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-?B activation to downregulate cytokine production. PLoS ONE. 2012;7:e41635 pubmed publisher
    ..To downregulate the host innate immunity, DENV-2 by itself is a weak inducer of type I IFN and cytokines, furthermore DENV-2 can also block the TLR-triggered ERK-NF-?B activation and cytokine production. ..
  4. Chiang A, Chen D, Cheng J, Chang T. Detection of human papillomavirus in squamous cell carcinoma arising from dermoid cysts. Taiwan J Obstet Gynecol. 2015;54:559-66 pubmed publisher
    ..Our data suggest that high-risk HPV infection might be a causal factor that induces malignant transformation of MCT into SCC of the ovary, although further investigation is still required. ..
  5. Chang J, Yang C, Chen B, Chen Y, Chang T. Complete genome sequence of the first human parechovirus type 3 isolated in Taiwan. J Chin Med Assoc. 2017;80:737-739 pubmed publisher
    ..All HPeV3 isolates possess at least 97% amino acid identity. The analysis of the genome sequence of HPeV3 VGHKS-2007 will facilitate future investigations of the epidemiology and pathogenicity of HPeV3 infection. ..
  6. Lin T, Su H, Kang H, Chang T. The Interactive Roles of Lipopolysaccharides and dsRNA/Viruses on Respiratory Epithelial Cells and Dendritic Cells in Allergic Respiratory Disorders: The Hygiene Hypothesis. Int J Mol Sci. 2017;18: pubmed publisher
    ..Several hygiene hypothesis-related phenomena, seemingly conflicting, are also discussed in this review, along with their proposed mechanisms. ..