Li Yeh Chuang

Summary

Affiliation: I-Shou University
Country: Taiwan

Publications

  1. pmc hSAGEing: an improved SAGE-based software for identification of human tissue-specific or common tumor markers and suppressors
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 5:e14369. 2010
  2. pmc CpGPAP: CpG island predictor analysis platform
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Genet 13:13. 2012
  3. pmc URPD: a specific product primer design tool
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Res Notes 5:306. 2012
  4. doi request reprint Specific primer design for the polymerase chain reaction
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    Biotechnol Lett 35:1541-9. 2013
  5. ncbi request reprint Associate PCR-RFLP assay design with SNPs based on genetic algorithm in appropriate parameters estimation
    Li Yeh Chuang
    Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung 84008, Taiwan
    IEEE Trans Nanobioscience 12:119-27. 2013
  6. pmc SNP-RFLPing: restriction enzyme mining for SNPs in genomes
    Hsueh Wei Chang
    Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Taiwan
    BMC Genomics 7:30. 2006
  7. pmc LD2SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs
    Hsueh Wei Chang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Genet 10:26. 2009
  8. ncbi request reprint Improved binary PSO for feature selection using gene expression data
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung 840, Taiwan
    Comput Biol Chem 32:29-37. 2008
  9. pmc V-MitoSNP: visualization of human mitochondrial SNPs
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, 840, Taiwan
    BMC Bioinformatics 7:379. 2006
  10. doi request reprint Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan
    Gau Tyan Lin
    Department of Orthopedic Surgery, Kaohsiung Medical University, Chung Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    OMICS 13:165-72. 2009

Collaborators

Detail Information

Publications60

  1. pmc hSAGEing: an improved SAGE-based software for identification of human tissue-specific or common tumor markers and suppressors
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    PLoS ONE 5:e14369. 2010
    ..There are currently many well-developed SAGE tools. However, the cross-comparison of different tissues is seldom addressed, thus limiting the identification of common- and tissue-specific tumor markers...
  2. pmc CpGPAP: CpG island predictor analysis platform
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Genet 13:13. 2012
    ..Genomic islands play an important role in medical, methylation and biological studies. To explore the region, we propose a CpG islands prediction analysis platform for genome sequence exploration (CpGPAP)...
  3. pmc URPD: a specific product primer design tool
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Res Notes 5:306. 2012
    ..Here, we present a currently available software that is not located in analyzing large sequence but used for a rather straight-forward way of visualizing the primer design process for infrequent users...
  4. doi request reprint Specific primer design for the polymerase chain reaction
    Li Yeh Chuang
    Department of Chemical Engineering, Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    Biotechnol Lett 35:1541-9. 2013
    ..In addition, characteristics of population-based methods used in primer design are discussed in detail. ..
  5. ncbi request reprint Associate PCR-RFLP assay design with SNPs based on genetic algorithm in appropriate parameters estimation
    Li Yeh Chuang
    Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung 84008, Taiwan
    IEEE Trans Nanobioscience 12:119-27. 2013
    ..We have provided an easy and kindly interface to assist the researchers designing their PCR-RFLP assay for SNP genotyping. The program is implemented in JAVA and is freely available at http://bio.kuas.edu.tw/ganpd/...
  6. pmc SNP-RFLPing: restriction enzyme mining for SNPs in genomes
    Hsueh Wei Chang
    Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Taiwan
    BMC Genomics 7:30. 2006
    ..Here, we describe a web-based software, named SNP-RFLPing, which provides the restriction enzyme for RFLP assays on a batch of SNPs and genes from the human, rat, and mouse genomes...
  7. pmc LD2SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs
    Hsueh Wei Chang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    BMC Genet 10:26. 2009
    ..Linkage disequilibrium (LD) mapping is commonly used to evaluate markers for genome-wide association studies. Most types of LD software focus strictly on LD analysis and visualization, but lack supporting services for genotyping...
  8. ncbi request reprint Improved binary PSO for feature selection using gene expression data
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung 840, Taiwan
    Comput Biol Chem 32:29-37. 2008
    ....
  9. pmc V-MitoSNP: visualization of human mitochondrial SNPs
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, 840, Taiwan
    BMC Bioinformatics 7:379. 2006
    ..The inherent problem associated with mtDNA sequences in BLAST of the NCBI database was also solved...
  10. doi request reprint Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan
    Gau Tyan Lin
    Department of Orthopedic Surgery, Kaohsiung Medical University, Chung Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    OMICS 13:165-72. 2009
    ....
  11. pmc SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
    Hsueh Wei Chang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    BMC Bioinformatics 11:173. 2010
    ....
  12. doi request reprint A combined bisulfite restriction analysis bioinformatics tool: methyl-typing
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    Methods Mol Biol 791:73-88. 2011
    ..It is a fast and efficient tool for providing all possible methylation sites of restriction enzymes...
  13. doi request reprint Dynamic programming for single nucleotide polymorphism ID identification in systematic association studies
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 25:165-76. 2009
    ..It is freely available at http://bio.kuas.edu.tw/SNPosition/...
  14. ncbi request reprint SNP ID-info: SNP ID searching and visualization platform
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Taiwan, ROC
    OMICS 12:217-26. 2008
    ..In conclusion, the SNP ID-info provides a visualized SNP ID environment for multiple inputs and assists systematic SNP association studies. The server and user manual are available at http://bio.kuas.edu.tw/snpid-info...
  15. doi request reprint Methyl-Typing: an improved and visualized COBRA software for epigenomic studies
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    FEBS Lett 584:739-44. 2010
    ..Therefore, the Methyl-Typing tool provides a comprehensive COBRA-restriction enzyme mining. It is freely available at http://bio.kuas.edu.tw/methyl-typing...
  16. ncbi request reprint Restriction enzyme mining for SNPs in genomes
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan, ROC
    Anticancer Res 28:2001-7. 2008
    ....
  17. ncbi request reprint Odds ratio-based genetic algorithms for generating SNP barcodes of genotypes to predict disease susceptibility
    Hsueh Wei Chang
    Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan
    OMICS 12:71-81. 2008
    ..Therefore, this paper introduces a powerful procedure for analysis of disease-associated SNP barcode in genome-wide genes...
  18. doi request reprint Features for computational operon prediction in prokaryotes
    Li Yeh Chuang
    Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I Shou University, Taiwan
    Brief Funct Genomics 11:291-9. 2012
    ....
  19. doi request reprint Seq-SNPing: multiple-alignment tool for SNP discovery, SNP ID identification, and RFLP genotyping
    Hsueh Wei Chang
    Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC
    OMICS 13:253-60. 2009
    ..The software is fully compatible with Microsoft Windows. The program and user manual are available at http://bio.kuas.edu.tw/Seq-SNPing for download...
  20. doi request reprint Evaluation of breast cancer susceptibility using improved genetic algorithms to generate genotype SNP barcodes
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung 80778, Taiwan
    IEEE/ACM Trans Comput Biol Bioinform 10:361-71. 2013
    ..A more specific SNP-SNP interaction profile for the risk of breast cancer is also provided. ..
  21. doi request reprint Chaotic particle swarm optimization for detecting SNP-SNP interactions for CXCL12-related genes in breast cancer prevention
    Li Yeh Chuang
    Institute of Biotechnology and Chemical Engineering, I Shou University, Taiwan
    Eur J Cancer Prev 21:336-42. 2012
    ..The CPSO method can effectively identify SNP-SNP interactions in complex biological relationships underlying the progression of breast cancer...
  22. pmc A hybrid BPSO-CGA approach for gene selection and classification of microarray data
    Li Yeh Chuang
    Department of Chemical Engineering, and Institute of Biotechnology and Chemical Engineering, I Shou University Kaohsiung, Taiwan
    J Comput Biol 19:68-82. 2012
    ..The experimental results indicate that the proposed method not only effectively reduce the number of genes expression level, but also achieves a low classification error rate...
  23. doi request reprint Chaotic genetic algorithm for gene selection and classification problems
    Li Yeh Chuang
    Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan, P R China
    OMICS 13:407-20. 2009
    ..The experimental results show that the proposed method not only effectively reduced the number of gene expression levels, but also achieved lower classification error rates than other methods...
  24. doi request reprint Generating SNP barcode to evaluate SNP-SNP interaction of disease by particle swarm optimization
    Hsueh Wei Chang
    Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan
    Comput Biol Chem 33:114-9. 2009
    ..Therefore, this paper introduces a powerful procedure to analyze disease-associated SNP-SNP interaction in genome-wide genes...
  25. doi request reprint Particle swarm optimization algorithm for analyzing SNP-SNP interaction of renin-angiotensin system genes against hypertension
    Shyh Jong Wu
    Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan
    Mol Biol Rep 40:4227-33. 2013
    ..In conclusion, this study demonstrated that non-significant SNPs may generate the joint effect in association study. Our proposed PSO algorithm is effective to identify the best protective SNP barcodes against hypertension...
  26. doi request reprint Computational analysis of simulated SNP interactions between 26 growth factor-related genes in a breast cancer association study
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan, Republic of China
    OMICS 15:399-407. 2011
    ..01) for specific SNP barcodes with two to five SNPs. Therefore, we were able to identify potential combined growth factor-related genes together with their SNP barcodes that were protective against breast cancer by in silico analysis...
  27. pmc Conserved PCR primer set designing for closely-related species to complete mitochondrial genome sequencing using a sliding window-based PSO algorithm
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    PLoS ONE 6:e17729. 2011
    ..However, current algorithms and tools are mostly focused on the primer design for a local region in the genomic sequence. Accordingly, it is still challenging to provide the primer sets for the entire mtDNA...
  28. pmc An improved PSO algorithm for generating protective SNP barcodes in breast cancer
    Li Yeh Chuang
    Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    PLoS ONE 7:e37018. 2012
    ..However, this PSO does not guarantee to find the best result in every implement, especially when high-dimensional data is investigated for SNP-SNP interactions...
  29. doi request reprint Tabu search and binary particle swarm optimization for feature selection using microarray data
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    J Comput Biol 16:1689-703. 2009
    ..Experimental results show that our method simplifies features effectively and either obtains higher classification accuracy or uses fewer features compared to other feature selection methods...
  30. doi request reprint Tag SNP selection using particle swarm optimization
    Li Yeh Chuang
    Dept of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    Biotechnol Prog 26:580-8. 2010
    ..For STAMPA and SVM/STSA, BPSO effective improved prediction accuracy for smaller and larger scale data sets. These results demonstrate that the BPSO method selects tag SNP with higher accuracy no matter the scale of data sets is used...
  31. doi request reprint Novel generating protective single nucleotide polymorphism barcode for breast cancer using particle swarm optimization
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    Cancer Epidemiol 33:147-54. 2009
    ..Simultaneous analyses for multiple SNP interactions associated with many diseases and cancers are essential; however, these analyses are still computationally challenging...
  32. ncbi request reprint Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility
    Jin Bor Chen
    Division of Nephrology, Department of Internal Medicine, Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Mitochondrial DNA 25:231-7. 2014
    ..In this study, we aimed to improve the analysis of SNP-SNP interactions within the mitochondrial D-loop in chronic dialysis...
  33. ncbi request reprint An improved PCR method for gender identification of eagles
    Hsueh Wei Chang
    Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan
    Mol Cell Probes 22:184-8. 2008
    ..When used with 28 samples of S. cheela hoya, our improved universal primers provided a fast and precise gender identification assay...
  34. doi request reprint Drug-SNPing: an integrated drug-based, protein interaction-based tagSNP-based pharmacogenomics platform for SNP genotyping
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    Bioinformatics 29:758-64. 2013
    ..Thus, users can enter any drug keywords/brand names to obtain immediate information that is highly relevant to genotyping for pharmacogenomics research...
  35. doi request reprint An introduction to mitochondrial informatics
    Hsueh Wei Chang
    Department of Biomedical Science and Environmental Biology, Center of Excellence for Environmental Medicine, Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan
    Methods Mol Biol 628:259-74. 2010
    ..Some databases with similar function are integrated and compared...
  36. doi request reprint Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratio-based genetic algorithms
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 28:362-8. 2012
    ..In conclusion, the proposed OR-GA method successfully generates SNP barcodes, which allow oral cancer risk to be evaluated and in the process the OR-GA method identifies possible SNP-SNP interactions...
  37. pmc Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    BMC Bioinformatics 11:509. 2010
    ..It is a time- and cost-effective SNP genotyping method that has the advantage of simplicity. However, computation of feasible CTPP primers is still challenging...
  38. pmc MDR-ER: balancing functions for adjusting the ratio in risk classes and classification errors for imbalanced cases and controls using multifactor-dimensionality reduction
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan
    PLoS ONE 8:e79387. 2013
    ..Consequently, results for classification error rates and odds ratios (OR) may provide surprising values in that the true positive (TP) value is often small...
  39. ncbi request reprint Fuzzy support vector machines for adaptive Morse code recognition
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung 807, Taiwan
    Med Eng Phys 28:925-31. 2006
    ..Statistical analyses demonstrated that the proposed method elicited a higher recognition rate than other algorithms in the literature...
  40. ncbi request reprint Morse code application for wireless environmental control systems for severely disabled individuals
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung 807, Taiwan, ROC
    IEEE Trans Neural Syst Rehabil Eng 11:463-9. 2003
    ..Experimental results revealed that three participants with physical handicaps were able to gain access to electronic facilities after two months' practice with the new system...
  41. pmc Identifying the association rules between clinicopathologic factors and higher survival performance in operation-centric oral cancer patients using the Apriori algorithm
    Jen Yang Tang
    Department of Radiation Oncology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Biomed Res Int 2013:359634. 2013
    ....
  42. doi request reprint Chemical composition and antibacterial activities of Illicium verum against antibiotic-resistant pathogens
    Jyh Ferng Yang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    J Med Food 13:1254-62. 2010
    ..These extracts from I. verum can be further developed into antibiotic medicines due to their proven antibacterial activity...
  43. pmc Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis
    Jin Bor Chen
    Division of Nephrology, Department of Internal Medicine, Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    PLoS ONE 7:e41125. 2012
    ..The aim of this study was to investigate the prevalence of single nucleotide polymorphisms (SNPs) within the D-loop among chronic dialysis patients and healthy controls...
  44. pmc Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome
    Li Yeh Chuang
    Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    PLoS ONE 6:e21036. 2011
    ..These islands are usually located in the 5' end of genes. Recently, several algorithms for the prediction of CpG islands have been proposed...
  45. doi request reprint Specific PCR product primer design using memetic algorithm
    Cheng Hong Yang
    Dept of Electronic Engineering, National Kaohsiung University of Applied Sciences, Taiwan
    Biotechnol Prog 25:745-53. 2009
    ..The results further indicate that the proposed method finds optimal or near-optimal primer sets and effective PCR products in a dry dock experiment. Related materials are available online at http://bio.kuas.edu.tw/ma-pd/...
  46. doi request reprint Genotype and antibiotic susceptibility patterns of drug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii isolates in Taiwan
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan, Republic of China
    Microb Drug Resist 14:281-8. 2008
    ..The results obtained from this study reveal that the majority of these isolates displayed multiple drug resistance phenotypes that were associated with their mutational gene profiles...
  47. doi request reprint A hybrid feature selection method for DNA microarray data
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung 80041, Taiwan
    Comput Biol Med 41:228-37. 2011
    ..The classification accuracy obtained by the proposed method was higher in ten out of the eleven gene expression data set test problems when compared to other classification methods from the literature...
  48. pmc Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress
    Chi Chen Yeh
    Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
    BMC Complement Altern Med 12:142. 2012
    ..Previously, we found that water extract of G. tenuistipitata was able to modulate oxidative stress-induced DNA damage and its related cellular responses...
  49. pmc Binary particle swarm optimization for operon prediction
    Li Yeh Chuang
    Department of Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    Nucleic Acids Res 38:e128. 2010
    ..This method has enabled us to predict operons with high accuracy for these three genomes, for which only limited data on the properties of the operon structure exists...
  50. ncbi request reprint PPO: predictor for prokaryotic operons
    Li Yeh Chuang
    Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan
    Bioinformatics 26:3127-8. 2010
    ....
  51. ncbi request reprint SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women
    Gau Tyan Lin
    Department of Orthopaedic Surgery, Chung Ho Memorial Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
    Chin J Physiol 51:32-41. 2008
    ..54- to 4.68-fold increased risk for low BMD, comparing to other SNP combinations. In conclusion, our data suggest that several gene polymorphisms may be cooperatively involved in the development of osteoporosis...
  52. doi request reprint A two-stage feature selection method for gene expression data
    Li Yeh Chuang
    Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung, Taiwan, Republic of China
    OMICS 13:127-37. 2009
    ..The experimental results show that the proposed method can effectively select relevant gene subsets, and achieves higher classification accuracy than previous studies...
  53. pmc Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer
    Li Yeh Chuang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, 415 Chien Kung Road, Kaohsiung 80778, Taiwan
    J Clin Bioinforma 3:4. 2013
    ..e., the high/low risk combinations of SNPs...
  54. pmc Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung 80778, Taiwan
    Biomed Res Int 2014:172049. 2014
    ..This study indicates that DBM-PSO is a robust and precise algorithm for determination of gene-gene interaction models for breast cancer. ..
  55. doi request reprint Operon prediction using chaos embedded particle swarm optimization
    Li Yeh Chuang
    I Shou University, Kaohsiung
    IEEE/ACM Trans Comput Biol Bioinform 10:1299-309. 2013
    ..The proposed method also achieved a good balance between sensitivity and specificity when compared to methods from the literature. ..
  56. doi request reprint Antioxidant activity of various parts of Cinnamomum cassia extracted with different extraction methods
    Cheng Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung 807, Taiwan
    Molecules 17:7294-304. 2012
    ..Based on the results, the ethanol extracts of Cinnamon barks have potential value as an antioxidant substitute and this study also provide a better technique to extract the natural antioxidant substances from C. cassia...
  57. doi request reprint Fast quantification of S-adenosyl-L-methionine in dietary health products utilizing reversed-phase high-performance liquid chromatography: teaching an old method new tricks
    Jing Ru Liou
    Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
    Planta Med 80:243-8. 2014
    ..The developed protocol is robust, fast, and suitable for the quality control analysis of yeast and commercial S-adenosyl-L-methionine products. ..
  58. ncbi request reprint Counter-propagation network with variable degree variable step size LMS for single switch typing recognition
    Cheng Huei Yang
    Department of Electronics Communication Engineering, National Kaohsiung Institute of Marine Technology, Taiwan
    Biomed Mater Eng 14:23-32. 2004
    ..Statistical analyses demonstrated that the proposed method elicited a better recognition rate in comparison to alternative methods in the literature...
  59. doi request reprint Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan
    Ching Yu Yen
    Department of Oral and Maxillofacial Surgery, Chi Mei Medical Center, Tainan, and School of Dentistry, Taipei Medical University, Taipei, Taiwan
    J Oral Pathol Med 37:271-7. 2008
    ..In this study, we focused on the joint effect for SNP combinations of four DNA repair genes, X-ray repair cross-complementing groups (XRCCs) 1-4, involved in major cancer-related pathways...