Hsiao Ling Chen

Summary

Affiliation: Chung Shan Medical University
Country: Taiwan

Publications

  1. ncbi Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind trial
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Taichung, Taiwan, R O C
    J Am Coll Nutr 22:36-42. 2003
  2. ncbi Inhibitory effects of a soluble dietary fiber from Amorphophallus konjac on cytotoxicity and DNA damage induced by fecal water in Caco-2 cells
    Shu Lan Yeh
    School of Nutrition, Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan, ROC
    Planta Med 73:1384-8. 2007
  3. ncbi Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo-controlled, diet-controlled trial
    Hsiao Ling Chen
    Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan 402
    J Am Coll Nutr 27:102-8. 2008
  4. ncbi Antioxidative and hepatoprotective effects of fructo-oligosaccharide in d-galactose-treated Balb/cJ mice
    Hsiao Ling Chen
    School of Nutrition, Chung Shan Medical University, Taichung City, Taiwan, ROC
    Br J Nutr 105:805-9. 2011
  5. ncbi Comparative effects of cellulose and soluble fibers (pectin, konjac glucomannan, inulin) on fecal water toxicity toward Caco-2 cells, fecal bacteria enzymes, bile acid, and short-chain fatty acids
    Hsiao Ling Chen
    School of Nutrition, Chung Shan Medical University, and Department of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan
    J Agric Food Chem 58:10277-81. 2010
  6. ncbi Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults
    Hsiao Ling Chen
    Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan
    Nutrition 22:1112-9. 2006
  7. ncbi Unhydrolyzed and hydrolyzed konjac glucomannans modulated cecal and fecal microflora in Balb/c mice
    Hsiao Ling Chen
    School of Nutrition, Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan, Republic of China
    Nutrition 21:1059-64. 2005
  8. ncbi Effects of Taiwanese yam (Dioscorea japonica Thunb var. pseudojaponica Yamamoto) on upper gut function and lipid metabolism in Balb/c mice
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Chung Shan Medical University, Taichung, Taiwan, People s Republic of China
    Nutrition 19:646-51. 2003
  9. ncbi Fiber intake and food selection of the elderly in Taiwan
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Chung Shan Medical University, Republic of China, Taichung, Taiwan, Republic of China
    Nutrition 19:332-6. 2003
  10. ncbi Fructo-oligosaccharide systemically diminished D-galactose-induced oxidative molecule damages in BALB/cJ mice
    Chien Hsun Hsia
    Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, ROC
    Br J Nutr 107:1787-92. 2012

Collaborators

  • Wei Chen
  • Shu Lan Yeh
  • Wayne Huey Herng Sheu
  • Yung Po Liaw
  • You Chan
  • Je Ruei Liu
  • Shiow Luan Tsay
  • Chuan Mu Chen
  • Wen Tzu Wu
  • Chih Jie Shen
  • Yu Tang Tung
  • Chi Hua Yen
  • Fang Chueh Liu
  • Yi Wen Kuo
  • Cheng Wei Lai
  • Chih Ching Yen
  • Shinn Chih Wu
  • Sen Wei Tsai
  • Chien Hsun Hsia
  • Yun Hua Tseng
  • Meng Chih Lee
  • Yi Wen Lai
  • Winston T K Cheng
  • A Li Hsu
  • Ting Yu Tang
  • Chia Hui Chuang
  • Shang Hsun Yang
  • Ying Jui Ho
  • Cheng Hsin Wang
  • Tung Chou Tsai
  • Yu Ping Kuan
  • Han Chung Cheng
  • Chien Yu Lin
  • Wu Huei Hsu
  • Willie Lin
  • Kowit Yu Chong
  • Shih Rong Wang
  • Chuan-Mu Chen
  • Tien-Shuh Yang
  • Meng Fu Kuo
  • Chung Nan Weng
  • Chung-Nan Weng
  • Shih-Rong Wang
  • Chih-Ching Yen
  • Tien Shuh Yang
  • Meng-Fu Kuo
  • Shinn-Chih Wu

Detail Information

Publications27

  1. ncbi Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind trial
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Taichung, Taiwan, R O C
    J Am Coll Nutr 22:36-42. 2003
    ..6 g/day) for 28 days on blood lipid and glucose levels in hyperlipidemic type 2 diabetic patients and the possible mechanism for the reductions in blood lipid levels...
  2. ncbi Inhibitory effects of a soluble dietary fiber from Amorphophallus konjac on cytotoxicity and DNA damage induced by fecal water in Caco-2 cells
    Shu Lan Yeh
    School of Nutrition, Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan, ROC
    Planta Med 73:1384-8. 2007
    ..FF: fiber free FO: oligofructose KGM: konjac glucomannan...
  3. ncbi Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo-controlled, diet-controlled trial
    Hsiao Ling Chen
    Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan 402
    J Am Coll Nutr 27:102-8. 2008
    ..In addition, the mechanisms by which KGM modulated the bowel habit were explored...
  4. ncbi Antioxidative and hepatoprotective effects of fructo-oligosaccharide in d-galactose-treated Balb/cJ mice
    Hsiao Ling Chen
    School of Nutrition, Chung Shan Medical University, Taichung City, Taiwan, ROC
    Br J Nutr 105:805-9. 2011
    ....
  5. ncbi Comparative effects of cellulose and soluble fibers (pectin, konjac glucomannan, inulin) on fecal water toxicity toward Caco-2 cells, fecal bacteria enzymes, bile acid, and short-chain fatty acids
    Hsiao Ling Chen
    School of Nutrition, Chung Shan Medical University, and Department of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan
    J Agric Food Chem 58:10277-81. 2010
    ....
  6. ncbi Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults
    Hsiao Ling Chen
    Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan
    Nutrition 22:1112-9. 2006
    ..Konjac glucomannan (KGM) has been shown to relieve constipation, which could be associated with increased stool bulk and improved colonic ecology...
  7. ncbi Unhydrolyzed and hydrolyzed konjac glucomannans modulated cecal and fecal microflora in Balb/c mice
    Hsiao Ling Chen
    School of Nutrition, Institute of Nutritional Science, Chung Shan Medical University, Taichung, Taiwan, Republic of China
    Nutrition 21:1059-64. 2005
    ..Short-chain fatty acid concentrations in cecal content were also determined...
  8. ncbi Effects of Taiwanese yam (Dioscorea japonica Thunb var. pseudojaponica Yamamoto) on upper gut function and lipid metabolism in Balb/c mice
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Chung Shan Medical University, Taichung, Taiwan, People s Republic of China
    Nutrition 19:646-51. 2003
    ..This study investigated the effects of a Taiwanese yam, Dioscorea japonica Thunb var. pseudojaponica Yamamoto, on upper gut function and lipid metabolism in adult Balb/c mice...
  9. ncbi Fiber intake and food selection of the elderly in Taiwan
    Hsiao Ling Chen
    Institute of Nutritional Science, School of Nutrition, Chung Shan Medical University, Republic of China, Taichung, Taiwan, Republic of China
    Nutrition 19:332-6. 2003
    ..We assessed fiber intakes and determined the major food categories that contribute to dietary fiber intakes in the Taiwanese elderly. We also examined the association between fiber intake and health status...
  10. ncbi Fructo-oligosaccharide systemically diminished D-galactose-induced oxidative molecule damages in BALB/cJ mice
    Chien Hsun Hsia
    Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, ROC
    Br J Nutr 107:1787-92. 2012
    ..c. DG treatment in younger BALB/cJ mice resembled the oxidative status in older mice. FO supplementation systemically prevented DG-induced oxidative stress, probably through its fermentation products and prebiotic effect...
  11. ncbi Long-term supplementation of isomalto-oligosaccharides improved colonic microflora profile, bowel function, and blood cholesterol levels in constipated elderly people--a placebo-controlled, diet-controlled trial
    Chi Hua Yen
    Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan
    Nutrition 27:445-50. 2011
    ..We also assessed whether the effect of IO was sustained after its withdrawal...
  12. ncbi Konjac glucomannan and inulin systematically modulate antioxidant defense in rats fed a high-fat fiber-free diet
    Wen Tzu Wu
    School of Nutrition, Chung Shan Medical University, Taichung, Taiwan
    J Agric Food Chem 59:9194-200. 2011
    ..These results suggest that in vivo utilization of KGM and inulin stimulated both local and systemic antioxidative defense systems in rats...
  13. ncbi Effects of konjac glucomannan on putative risk factors for colon carcinogenesis in rats fed a high-fat diet
    Wen Tzu Wu
    School of Nutrition, Chung Shan Medical University, Taichung, Taiwan
    J Agric Food Chem 59:989-94. 2011
    ..Therefore, the present study suggests that KGM potentially attenuated the high fat-induced risk in colon carcinogenesis...
  14. ncbi Beneficial effects of fructo-oligosaccharides supplementation on fecal bifidobacteria and index of peroxidation status in constipated nursing-home residents--a placebo-controlled, diet-controlled trial
    Chi Hua Yen
    Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan
    Nutrition 27:323-8. 2011
    ..The associations of fecal bifidobacteria and blood measurements were also examined...
  15. ncbi Aerosolized human extracellular superoxide dismutase prevents hyperoxia-induced lung injury
    Chih Ching Yen
    Department of Life Sciences, and Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan
    PLoS ONE 6:e26870. 2011
    ..The results encourage the use of an aerosol therapy with EC-SOD in intensive care units to reduce oxidative injury in patients with severe hypoxemic respiratory failure, including acute respiratory distress syndrome (ARDS)...
  16. ncbi Ameliorative effects of konjac glucomannan on human faecal β-glucuronidase activity, secondary bile acid levels and faecal water toxicity towards Caco-2 cells
    Wen Tzu Wu
    School of Nutrition, Chung Shan Medical University, No 110, Section 1, Jianguo North Road, Taichung City 402, Taiwan, ROC
    Br J Nutr 105:593-600. 2011
    ....
  17. ncbi Treadmill running upregulates the expression of acetylcholine receptor in rat gastrocnemius following botulinum toxin A injection
    Sen Wei Tsai
    Department of Life Sciences, Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan
    J Orthop Res 31:125-31. 2013
    ..The expression of genes associated with neurite and AChR regeneration following treadmill exercise was upregulated, which may have contributed to enhanced recovery of gastrocnemius strength...
  18. ncbi Differential differences in methylation status of putative imprinted genes among cloned swine genomes
    Chih Jie Shen
    Department of Life Sciences, and Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan
    PLoS ONE 7:e32812. 2012
    ..Understanding the aberrant pattern of gene imprinting would permit improvements in future cloning techniques...
  19. ncbi Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic mice
    Yu Tang Tung
    Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan
    Mol Nutr Food Res 55:1036-43. 2011
    ..We investigated the inhibition of pulmonary tumor formation through treatment with curcumin in transgenic mice...
  20. ncbi Application of porcine lipase secreted by pichia pastoris to improve fat digestion and growth performance of postweaning piglets
    Fang Chueh Liu
    Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan
    J Agric Food Chem 58:3322-9. 2010
    ..These results suggested that the porcine lipase protein yielded by transformed yeast cells may improve fat digestibility and enhance the growth performance in postweaning piglets...
  21. ncbi Production of recombinant porcine colipase secreted by Pichia pastoris and its application to improve dietary fat digestion and growth of postweaning piglets
    Fang Chueh Liu
    Dept of Life Sciences, National Chung Hsing University, Taichung, Taiwan
    Biotechnol Prog 24:1333-41. 2008
    ..16.37 mg/dL; P < 0.0001). These experimental data suggest that the use of recombinant porcine colipase as a dietary supplement provides an alternative approach for improving fat digestion and enhancing growth in postweaning piglets...
  22. ncbi Hypocholesterolaemic effects of milk-kefir and soyamilk-kefir in cholesterol-fed hamsters
    Je Ruei Liu
    Department of Biotechnology, National Formosa University, Taiwan
    Br J Nutr 95:939-46. 2006
    ..These findings demonstrate that soyamilk-kefir may be considered to be among the more promising food components in terms of preventing CVD through its hypocholesterolaemic action...
  23. ncbi Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance
    Shinn Chih Wu
    Department of Animal Science and Technology, National Taiwan University, Taipei 106, Taiwan
    J Agric Food Chem 55:4670-7. 2007
    ..Furthermore, this enhanced growth performance in suckling mice was proportional to the concentration of pLF present in milk...
  24. ncbi Recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonatal mice from a lethal challenge with enterovirus type 71
    Hsiao Ling Chen
    Department of Molecular Biotechnology, Da Yeh University, Changhwa 51501, Taiwan
    Vaccine 26:891-8. 2008
    ..Our data suggest that oral intake of pLF-enriched milk exhibited the ability to prevent infection with EV71. The study also provides an animal model for validating the protective effects of pLF...
  25. ncbi Synthetic porcine lactoferricin with a 20-residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans
    Hsiao-Ling Chen
    Department of Molecular Biotechnology, Da-Yeh University, Changhwa, Taiwan
    J Agric Food Chem 54:3277-82. 2006
    ..LFcin P-20 was 4 times more effective than human lactoferricin (LFcin H-20), but slightly less effective than bovine lactoferricin (LFcin B-20)...
  26. ncbi Production of recombinant porcine lactoferrin exhibiting antibacterial activity in methylotrophic yeast, Pichia pastoris
    Hsiao-Ling Chen
    Department of Molecular Biotechnology, Da-Yeh University, Changhwa, Taiwan
    J Mol Microbiol Biotechnol 8:141-9. 2004
    ..Our results suggested that the methylotrophic yeast-inducible system is suitable for large-scale production of active antibacterial rPLF glycoprotein...
  27. ncbi Effects of reflexotherapy on acute postoperative pain and anxiety among patients with digestive cancer
    Shiow Luan Tsay
    Graduate Institute of Nursing, National Taipei College of Nursing, Taipei, Taiwan
    Cancer Nurs 31:109-15. 2008
    ..05). Findings from this study provide nurses with an additional treatment to offer postoperative digestive cancer patients...