Chi Rei Wu

Summary

Affiliation: China Medical College
Country: Taiwan

Publications

  1. ncbi request reprint The ameliorating effects of LiuWei Dihuang Wang on cycloheximide-induced impairment of passive avoidance performance in rats
    Chi Rei Wu
    Institute of Chinese Pharmaceutical Sciences, China Medical University, 91 Hsieh Shih Road, Taichung, Taiwan, ROC
    J Ethnopharmacol 113:79-84. 2007
  2. ncbi request reprint The ameliorating effect of the water layer of Fructus Schisandrae on cycloheximide-induced amnesia in rats: interaction with drugs acting at neurotransmitter receptors
    M T Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, 40421, Republic of China
    Pharmacol Res 43:17-22. 2001
  3. ncbi request reprint Analgesic and anti-inflammatory property of the methanol extract from Ligustrum morrisonense leaves in rodents
    Chi Rei Wu
    Graduate Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, Taiwan
    Am J Chin Med 39:335-48. 2011
  4. ncbi request reprint The ameliorating effects of cognition-enhancing Chinese herbs on scopolamine- and MK-801-induced amnesia in rats
    Ying Chih Lin
    Institute of Chinese Pharmaceutical Sciences, China Medical College Taichung, Taiwan, ROC
    Am J Chin Med 31:543-9. 2003
  5. ncbi request reprint Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats
    Ming Chin Lu
    Post Baccalaureate School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    J Ethnopharmacol 112:552-6. 2007
  6. ncbi request reprint Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
    Planta Med 68:901-5. 2002
  7. ncbi request reprint Osthole improves aspects of spatial performance in ovariectomized rats
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, 404, Taiwan, R O C
    Am J Chin Med 32:11-20. 2004
  8. ncbi request reprint The ameliorating effects of luteolin on beta-amyloid-induced impairment of water maze performance and passive avoidance in rats
    Fan Shiu Tsai
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taichung, Taiwan
    Am J Chin Med 38:279-91. 2010
  9. doi request reprint The chalcone flavokawain B induces G2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway
    You Cheng Hseu
    Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung, Taiwan
    J Agric Food Chem 60:2385-97. 2012
  10. doi request reprint Neuroprotective effect of luteolin on amyloid beta protein (25-35)-induced toxicity in cultured rat cortical neurons
    Hao Yuan Cheng
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taichung, Taiwan, R O C
    Phytother Res 24:S102-8. 2010

Collaborators

Detail Information

Publications39

  1. ncbi request reprint The ameliorating effects of LiuWei Dihuang Wang on cycloheximide-induced impairment of passive avoidance performance in rats
    Chi Rei Wu
    Institute of Chinese Pharmaceutical Sciences, China Medical University, 91 Hsieh Shih Road, Taichung, Taiwan, ROC
    J Ethnopharmacol 113:79-84. 2007
    ..These results suggest that the ameliorating effects of LDW whose potency were parallel to treatment duration might be related to activating peripheral cholinergic neuronal system and modulating the central nervous system...
  2. ncbi request reprint The ameliorating effect of the water layer of Fructus Schisandrae on cycloheximide-induced amnesia in rats: interaction with drugs acting at neurotransmitter receptors
    M T Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, 40421, Republic of China
    Pharmacol Res 43:17-22. 2001
    ....
  3. ncbi request reprint Analgesic and anti-inflammatory property of the methanol extract from Ligustrum morrisonense leaves in rodents
    Chi Rei Wu
    Graduate Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, Taiwan
    Am J Chin Med 39:335-48. 2011
    ....
  4. ncbi request reprint The ameliorating effects of cognition-enhancing Chinese herbs on scopolamine- and MK-801-induced amnesia in rats
    Ying Chih Lin
    Institute of Chinese Pharmaceutical Sciences, China Medical College Taichung, Taiwan, ROC
    Am J Chin Med 31:543-9. 2003
    ..In conclusion, these Chinese herbs possess cognition-enhancing activities and anti-amnestic effects, but the mechanism of the effect of AB was different from those of OJ and CM...
  5. ncbi request reprint Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats
    Ming Chin Lu
    Post Baccalaureate School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    J Ethnopharmacol 112:552-6. 2007
    ....
  6. ncbi request reprint Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
    Planta Med 68:901-5. 2002
    ....
  7. ncbi request reprint Osthole improves aspects of spatial performance in ovariectomized rats
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, 404, Taiwan, R O C
    Am J Chin Med 32:11-20. 2004
    ..The action mechanism of the effects of osthole on performance deficits was related to the estrogen-like properties and activating the central cholinergic neuronal system...
  8. ncbi request reprint The ameliorating effects of luteolin on beta-amyloid-induced impairment of water maze performance and passive avoidance in rats
    Fan Shiu Tsai
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taichung, Taiwan
    Am J Chin Med 38:279-91. 2010
    ..The ameliorating mechanisms of luteolin on Abeta (1-40)-induced amnesia may be related to activating the anti-oxidation system...
  9. doi request reprint The chalcone flavokawain B induces G2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway
    You Cheng Hseu
    Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung, Taiwan
    J Agric Food Chem 60:2385-97. 2012
    ....
  10. doi request reprint Neuroprotective effect of luteolin on amyloid beta protein (25-35)-induced toxicity in cultured rat cortical neurons
    Hao Yuan Cheng
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taichung, Taiwan, R O C
    Phytother Res 24:S102-8. 2010
    ..Taken together, the results suggest that luteolin prevents Abeta (25-35)-induced apoptotic neuronal death through inhibiting the protein level of JNK, ERK and p38 MAP kinases and caspase 3 activations...
  11. doi request reprint Adherent properties and macrophage activation ability of 3 strains of lactic acid bacteria
    Wen Hsin Lin
    Dept of Pharmacy, School of Pharmacy, China Medical Univ, No 91, Hsueh Shih Rd, Taichung City 404, Taiwan, ROC
    J Food Sci 76:M1-7. 2011
    ....
  12. ncbi request reprint Effects of luteolin on learning acquisition in rats: involvement of the central cholinergic system
    Fan Shiu Tsai
    Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, Taiwan, ROC
    Life Sci 80:1692-8. 2007
    ..p.) on the deficits of passive avoidance performance induced by SCOP may be related to the increases in the activities of central muscarinic and nicotinic receptors...
  13. ncbi request reprint The ameliorating effects of acute and chronic administration of LiuWei Dihuang Wang on learning performance in rodents
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
    Biol Pharm Bull 26:156-61. 2003
    ..These results suggest that LDW possesses the anti-amnestic and cognitive-enhancing activities related to the memory processes, and these activities were parallel to treatment duration and dependent on the learning models...
  14. ncbi request reprint Anti-nociceptive and anti-inflammatory activity caused by Cistanche deserticola in rodents
    Li Wei Lin
    Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsieh Shih Road, Taichung, Taiwan, ROC
    J Ethnopharmacol 83:177-82. 2002
    ..Furthermore, the analgesic and anti-inflammatory effects of the butanolic layer of CD extract were not related to opioid receptors and immune system...
  15. ncbi request reprint Psoralen and isopsoralen, two coumarins of Psoraleae Fructus, can alleviate scopolamine-induced amnesia in rats
    Chi Rei Wu
    Institute of Chinese Pharmaceutical Sciences, Department of Pharmacy, China Medical University, and Taichung Hospital, Department of Health, Taiwan R O C
    Planta Med 73:275-8. 2007
    ....
  16. ncbi request reprint Effects of ferulic acid on the impairment of inhibitory avoidance performance in rats
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, R O C
    Planta Med 68:754-6. 2002
    ..Thus, the attenuating effects of ferulic acid on the avoidance performance impairment were related to memory processes, and might be enhancing the cholinergic activities and cerebral blood circle...
  17. doi request reprint Petroleum ether extract of Cnidium monnieri ameliorated scopolamine-induced amnesia through adrenal gland-mediated mechanism in male rats
    Chi Rei Wu
    Graduate Institute of Chinese Pharmaceutical Sciences, China Medical University, 91, Hsueh Shih Road, Taichung 40421, Taiwan, ROC
    J Ethnopharmacol 117:403-7. 2008
    ..Our previous study indicated petroleum ether layer of Cnidium monnieri L. Cuss. (CM) and its ingredient osthole could alleviate scopolamine-induced amnesia in female rats...
  18. doi request reprint Antioxidant phenolic profile from ethyl acetate fraction of Fructus Ligustri Lucidi with protection against hydrogen peroxide-induced oxidative damage in SH-SY5Y cells
    Heng Yin Ju
    The School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, and Taichung Hospital, Department of Health, No 91, Hsueh Shih Road, Taichung 40402, Taiwan, ROC
    Food Chem Toxicol 50:492-502. 2012
    ....
  19. ncbi request reprint Differential gene expression of scopolamine-treated rat hippocampus-application of cDNA microarray technology
    Ming Tsuen Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung 404, Taiwan, ROC
    Life Sci 73:1007-16. 2003
    ..Our result should provide an insight into the molecular study of scopolamine-induced memory impairment...
  20. doi request reprint Triterpenoid contents and anti-inflammatory properties of the methanol extracts of ligustrum species leaves
    Chi Rei Wu
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, 91 Hsieh Shih Road, Taichung 40402, Taiwan
    Molecules 16:1-15. 2011
    ..The effects of LP are partially related to the inhibition of cyclooxygenase-2 activity and a decrease in microvascular permeability via the actions of autocrines and kinins...
  21. doi request reprint Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes
    You Cheng Hseu
    Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung 40402, Taiwan
    Food Chem Toxicol 50:1245-55. 2012
    ..Nrf2 knockdown diminished the protective effects of ellagic acid. Therefore, ellagic acid may be useful for the treatment of UVA-induced skin damage...
  22. doi request reprint Review on experimental research of herbal medicines with anti-amnesic activity
    Ming Tsuen Hsieh
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taichung, Taiwan
    Planta Med 76:203-17. 2010
    ..Developing new drugs from herbal medicines for the treatment of amnesia is a hopeful attempt to meet the unmet medical needs...
  23. doi request reprint Induced apoptosis of Th2 lymphocytes and inhibition of airway hyperresponsiveness and inflammation by combined lactic acid bacteria treatment
    Wen Hsin Lin
    School of Pharmacy, China Medical University, Taichung, Taiwan
    Int Immunopharmacol 15:703-11. 2013
    ..This study may provide a basis for developing a novel therapeutic or protective method for airway allergic disease...
  24. ncbi request reprint Anxiolytic effect of berberine on exploratory activity of the mouse in two experimental anxiety models: interaction with drugs acting at 5-HT receptors
    Wen Huang Peng
    Graduated Institute of Chinese Pharmaceutical Sciences, China Medical University, 91 Hsueh Shih Rd, Taichung 404, Taiwan, ROC
    Life Sci 75:2451-62. 2004
    ..Moreover, BER decreased serotonergic system activity via activation of somatodendritic 5-HT1A autoreceptors and inhibition of postsynaptic 5-HT1A and 5-HT2 receptors...
  25. doi request reprint Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro
    Chi Rei Wu
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, No 91, Hsueh Shih Road, Taichung, 40402, Taiwan, ROC Electronic address
    Food Chem 127:564-71. 2011
    ..Among all Ligustrum species from Taiwan, Ligustrum morrisonense is presented as potential source of natural antioxidants...
  26. doi request reprint Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid
    Bor Ren Huang
    Department of Neurosurgery, Buddhist Tzu Chi General Hospital, Taichung Branch, Taichung, Taiwan
    Toxicol Appl Pharmacol 269:43-50. 2013
    ..HO-1 activator CoPP IX dramatically reversed LTA-induced iNOS expression. Our results provided mechanisms linking LTA and inflammation/anti-inflammation, and indicated that LTA plays a regulatory role in microglia activation...
  27. doi request reprint Carnosic acid prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells via mediation of glutathione synthesis
    Jing Hsien Chen
    Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan
    Chem Res Toxicol 25:1893-901. 2012
    ..The CA compound may be a promising candidate for neuroprotection in Parkinson's disease...
  28. ncbi request reprint Schizandrin protects primary cultures of rat cortical cells from glutamate-induced excitotoxicity
    Hao Yuan Cheng
    Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, Taiwan
    J Pharmacol Sci 107:21-31. 2008
    ..Taken together, these results suggest that schizandrin protected primary cultures of rat cortical cells against Glu-induced apoptosis through a mitochondria-mediated pathway and oxidative stress...
  29. doi request reprint Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis
    You Cheng Hseu
    Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung, Taiwan
    J Ethnopharmacol 135:762-71. 2011
    ..In this study, the ability of P. angulata to inhibit tumor metastasis and angiogenesis was investigated...
  30. ncbi request reprint Effects of noise on monoamine levels in the rat brain using in vivo microdialysis
    Huei Yann Tsai
    Institute of Medical Science and Department of Pharmacology, China Medical University, 91 Hsueh Shih Road, Taichung, Taiwan, R O C
    Pflugers Arch 450:83-7. 2005
    ..Other neurotransmitters (norepinephrine etc.) did not change significantly in any region. These results suggest that noise influences monoamine levels differently in different brain regions...
  31. pmc Guizhi-Fuling-Wan, a Traditional Chinese Herbal Medicine, Ameliorates Memory Deficits and Neuronal Apoptosis in the Streptozotocin-Induced Hyperglycemic Rodents via the Decrease of Bax/Bcl2 Ratio and Caspase-3 Expression
    Kuo Jen Wu
    Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, Taichung 40402, Taiwan
    Evid Based Complement Alternat Med 2012:656150. 2012
    ..GFW may have therapeutic effects in patients with diabetes-mellitus-induced neuropathology...
  32. ncbi request reprint The ameliorating effects of the cognitive-enhancing Chinese herbs on scopolamine-induced amnesia in rats
    M T Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taiwan, R O C
    Phytother Res 14:375-7. 2000
    ..Of ten Chinese herbs, only PG, PNG, GE and CC prolonged the SCOP-shortened STL. These results revealed that PG, PNG GE and CC administered orally for 1 week improved the SCOP-induced learning and memory deficit in rats...
  33. pmc Balanophora spicata and Lupeol Acetate Possess Antinociceptive and Anti-Inflammatory Activities In Vivo and In Vitro
    Yuh Fung Chen
    Department of Pharmacology, China Medical University, No 91 Hsueh Shih Road, Taichung 40402, Taiwan Department of Pharmacy, China Medical University Hospital, Taichung 40427, Taiwan
    Evid Based Complement Alternat Med 2012:371273. 2012
    ....
  34. pmc Green Tea Extract Ameliorates Learning and Memory Deficits in Ischemic Rats via Its Active Component Polyphenol Epigallocatechin-3-gallate by Modulation of Oxidative Stress and Neuroinflammation
    Kuo Jen Wu
    School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, 91 Hsueh Shih Road, Taichung 40402, Taiwan
    Evid Based Complement Alternat Med 2012:163106. 2012
    ..GTex and its active polyphenol EGCG improved learning and memory deficits in a cerebral ischemia animal model and such protection may be due to the reduction of oxidative stress and neuroinflammation...
  35. ncbi request reprint Antioxidant and antiproliferative activities of Desmodium triflorum (L.) DC
    Shang Chih Lai
    Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung, Taiwan
    Am J Chin Med 38:329-42. 2010
    ..The above experimental data indicated that D. triflorum was a potent antioxidant medicinal plant, and such efficacy may be mainly attributed to its polyphenolic compounds...
  36. ncbi request reprint Comparison with various parts of Broussonetia papyrifera as to the antinociceptive and anti-inflammatory activities in rodents
    Li Wei Lin
    Graduate School of Nursing, Hungkuang University, Taichung, Taiwan, ROC
    Biosci Biotechnol Biochem 72:2377-84. 2008
    ....
  37. ncbi request reprint p-Hydroxybenzyl alcohol attenuates learning deficits in the inhibitory avoidance task: involvement of serotonergic and dopaminergic systems
    C R Wu
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
    Chin J Physiol 39:265-73. 1996
    ..Such findings suggest that HBA may act through suppressing dopaminergic and serotonergic activities and thus improves learning...
  38. doi request reprint Anti-Helicobacter pylori activity of fermented milk with lactic acid bacteria
    Wen Hsin Lin
    School of Pharmacy, China Medical University, No 91, Hsueh Shih Road, Taichung City 404, Taiwan
    J Sci Food Agric 91:1424-31. 2011
    ..In addition, the exclusion effect of SCS against H. pylori infection of human gastric epithelial AGS cells was assayed...
  39. ncbi request reprint Reversal caused by n-butylidenephthalide from the deficits of inhibitory avoidance performance in rats
    M T Hsieh
    Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, ROC
    Planta Med 67:38-42. 2001
    ....